-
1
-
-
35348834158
-
Application of incretin mimetics and dipeptidyl peptidase IV inhibitors in managing type 2 diabetes mellitus
-
Boyle PJ, Freeman JS. Application of incretin mimetics and dipeptidyl peptidase IV inhibitors in managing type 2 diabetes mellitus. J Am Osteopath Assoc 2007; 107(suppl 3):S10-S16.
-
(2007)
J Am Osteopath Assoc
, vol.107
, Issue.SUPPL. 3
-
-
Boyle, P.J.1
Freeman, J.S.2
-
2
-
-
35348922883
-
The pathophysiologic role of incretins
-
Freeman JS. The pathophysiologic role of incretins. J Am Osteopath Assoc 2007; 107(suppl 3):S6-S9.
-
(2007)
J Am Osteopath Assoc
, vol.107
, Issue.SUPPL. 3
-
-
Freeman, J.S.1
-
3
-
-
33846006173
-
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
-
Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006; 368:1696-1705.
-
(2006)
Lancet
, vol.368
, pp. 1696-1705
-
-
Drucker, D.J.1
Nauck, M.A.2
-
4
-
-
9444244529
-
Gastric inhibitory polypeptide and glucagon-like peptide-1 in the pathogenesis of type 2 diabetes
-
Nauck MA, Baller B, Meier JJ. Gastric inhibitory polypeptide and glucagon-like peptide-1 in the pathogenesis of type 2 diabetes. Diabetes 2004; 53(suppl 3):S190-S196.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Nauck, M.A.1
Baller, B.2
Meier, J.J.3
-
5
-
-
48749089599
-
Emerging incretin based therapies for type 2 diabetes: incretin mimetics and DPP-4 inhibitors
-
Stonehouse A, Okerson T, Kendall D, Maggs D. Emerging incretin based therapies for type 2 diabetes: incretin mimetics and DPP-4 inhibitors. Curr Diabetes Rev 2008; 4:101-109.
-
(2008)
Curr Diabetes Rev
, vol.4
, pp. 101-109
-
-
Stonehouse, A.1
Okerson, T.2
Kendall, D.3
Maggs, D.4
-
6
-
-
33645961903
-
Gut peptides and the regulation of appetite
-
Huda MS, Wilding JP, Pinkney JH. Gut peptides and the regulation of appetite. Obes Rev 2006; 7:163-182.
-
(2006)
Obes Rev
, vol.7
, pp. 163-182
-
-
Huda, M.S.1
Wilding, J.P.2
Pinkney, J.H.3
-
8
-
-
34248223285
-
Biology of incretins: GLP-1 and GIP
-
Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007; 132:2131-2157.
-
(2007)
Gastroenterology
, vol.132
, pp. 2131-2157
-
-
Baggio, L.L.1
Drucker, D.J.2
-
10
-
-
0023638829
-
Glucagonlike peptide-1 7-36: a physiological incretin in man
-
Kreymann B, Williams G, Ghatei MA, Bloom SR. Glucagonlike peptide-1 7-36: a physiological incretin in man. Lancet 1987; 2:1300-1304.
-
(1987)
Lancet
, vol.2
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
11
-
-
0022461548
-
Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses
-
Nauck MA, Homberger E, Siegel EG, et al. Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab 1986; 63:492-498.
-
(1986)
J Clin Endocrinol Metab
, vol.63
, pp. 492-498
-
-
Nauck, M.A.1
Homberger, E.2
Siegel, E.G.3
-
12
-
-
0345374580
-
Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets
-
Farilla L, Bulotta A, Hirshberg B, et al. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology 2003; 144:5149-5158.
-
(2003)
Endocrinology
, vol.144
, pp. 5149-5158
-
-
Farilla, L.1
Bulotta, A.2
Hirshberg, B.3
-
13
-
-
44949134945
-
Exploiting the antidiabetic properties of incretins to treat type 2 diabetes mellitus: glucagon-like peptide 1 receptor agonists or insulin for patients with inadequate glycemic control?
-
Van Gaal LF, Gutkin SW, Nauck MA. Exploiting the antidiabetic properties of incretins to treat type 2 diabetes mellitus: glucagon-like peptide 1 receptor agonists or insulin for patients with inadequate glycemic control? Eur J Endocrinol 2008; 158:773-784.
-
(2008)
Eur J Endocrinol
, vol.158
, pp. 773-784
-
-
Van Gaal, L.F.1
Gutkin, S.W.2
Nauck, M.A.3
-
14
-
-
0028803336
-
Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects
-
Deacon CF, Nauck MA, Toft-Nielsen M, Pridal L, Willms B, Holst JJ. Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects. Diabetes 1995; 44:1126-1131.
-
(1995)
Diabetes
, vol.44
, pp. 1126-1131
-
-
Deacon, C.F.1
Nauck, M.A.2
Toft-Nielsen, M.3
Pridal, L.4
Willms, B.5
Holst, J.J.6
-
15
-
-
43149126332
-
Non-linear increase in GLP-1 levels in response to DPP-IV inhibition in healthy adult subjects
-
Dai H, Gustavson SM, Preston GM, Eskra JD, Calle R, Hirshberg B. Non-linear increase in GLP-1 levels in response to DPP-IV inhibition in healthy adult subjects. Diabetes Obes Metab 2008; 10:506-513.
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 506-513
-
-
Dai, H.1
Gustavson, S.M.2
Preston, G.M.3
Eskra, J.D.4
Calle, R.5
Hirshberg, B.6
-
17
-
-
0026721478
-
Rapid gastric emptying of an oral glucose solution in type 2 diabetic patients
-
Phillips WT, Schwartz JG, McMahan CA. Rapid gastric emptying of an oral glucose solution in type 2 diabetic patients. J Nucl Med 1992; 33:1496-1500.
-
(1992)
J Nucl Med
, vol.33
, pp. 1496-1500
-
-
Phillips, W.T.1
Schwartz, J.G.2
McMahan, C.A.3
-
18
-
-
0034880655
-
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients
-
Toft-Nielsen MB, Damholt MB, Madsbad S, et al. Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients. J Clin Endocrinol Metab 2001; 86:3717-3723.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3717-3723
-
-
Toft-Nielsen, M.B.1
Damholt, M.B.2
Madsbad, S.3
-
19
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Orskov C, Holst JJ, Ebert R, Creutzfeldt W. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 1993; 91:301-307.
-
(1993)
J Clin Invest
, vol.91
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
20
-
-
0037268159
-
A novel pathway for regulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in beta cells
-
Lynn FC, Thompson SA, Pospisilik JA, et al. A novel pathway for regulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in beta cells. FASEB J 2003; 17:91-93.
-
(2003)
FASEB J
, vol.17
, pp. 91-93
-
-
Lynn, F.C.1
Thompson, S.A.2
Pospisilik, J.A.3
-
21
-
-
0029856880
-
Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)-evidence for decreased glucagon-like peptide-1 secretion during oral glucose ingestion in NIDDM twins
-
Vaag AA, Holst JJ, Vølund A, Beck-Nielsen HB. Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)-evidence for decreased glucagon-like peptide-1 secretion during oral glucose ingestion in NIDDM twins. Eur J Endocrinol 1996; 135:425-432.
-
(1996)
Eur J Endocrinol
, vol.135
, pp. 425-432
-
-
Vaag, A.A.1
Holst, J.J.2
Vølund, A.3
Beck-Nielsen, H.B.4
-
22
-
-
0037667613
-
Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes
-
Meier JJ, Gallwitz B, Salmen S, et al. Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes. J Clin Endocrinol Metab 2003; 88:2719-2725.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2719-2725
-
-
Meier, J.J.1
Gallwitz, B.2
Salmen, S.3
-
23
-
-
0027248866
-
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
-
Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993; 36:741-744.
-
(1993)
Diabetologia
, vol.36
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Orskov, C.3
Holst, J.J.4
Willms, B.5
Creutzfeldt, W.6
-
24
-
-
34547586659
-
Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?
-
Knop FK, Vilsbøll T, Højberg PV, et al. Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state? Diabetes 2007; 56:1951-1959.
-
(2007)
Diabetes
, vol.56
, pp. 1951-1959
-
-
Knop, F.K.1
Vilsbøll, T.2
Højberg, P.V.3
-
25
-
-
34249741098
-
Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis
-
Lee YS, Shin S, Shigihara T, et al. Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis. Diabetes 2007; 56:1671-1679.
-
(2007)
Diabetes
, vol.56
, pp. 1671-1679
-
-
Lee, Y.S.1
Shin, S.2
Shigihara, T.3
-
26
-
-
48449093468
-
Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients
-
Muscelli E, Mari A, Casolaro A, et al. Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients. Diabetes 2008; 57:1340-1348.
-
(2008)
Diabetes
, vol.57
, pp. 1340-1348
-
-
Muscelli, E.1
Mari, A.2
Casolaro, A.3
-
27
-
-
0026542396
-
Insulinotropic action of glucagonlike peptide-I-(7-37) in diabetic and nondiabetic subjects
-
Nathan DM, Schreiber E, Fogel H, Mojsov S, Habener JF. Insulinotropic action of glucagonlike peptide-I-(7-37) in diabetic and nondiabetic subjects. Diabetes Care 1992; 15:270-276.
-
(1992)
Diabetes Care
, vol.15
, pp. 270-276
-
-
Nathan, D.M.1
Schreiber, E.2
Fogel, H.3
Mojsov, S.4
Habener, J.F.5
-
28
-
-
0038497464
-
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
-
Kolterman OG, Buse JB, Fineman MS, et al. Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 2003; 88:3082-3089.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3082-3089
-
-
Kolterman, O.G.1
Buse, J.B.2
Fineman, M.S.3
-
29
-
-
0037045845
-
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study
-
Zander M, Madsbad S, Madsen JL, Holst JJ. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. Lancet 2002; 359:824-830.
-
(2002)
Lancet
, vol.359
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Madsen, J.L.3
Holst, J.J.4
-
30
-
-
15444367142
-
Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus
-
Kolterman OG, Kim DD, Shen L, et al. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus. Am J Health Syst Pharm 2005; 62:173-181.
-
(2005)
Am J Health Syst Pharm
, vol.62
, pp. 173-181
-
-
Kolterman, O.G.1
Kim, D.D.2
Shen, L.3
-
31
-
-
7444228521
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
-
Buse JB, Henry RR, Han J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004; 27:2628-2635.
-
(2004)
Diabetes Care
, vol.27
, pp. 2628-2635
-
-
Buse, J.B.1
Henry, R.R.2
Han, J.3
-
33
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
-
DeFronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005; 28:1092-1100.
-
(2005)
Diabetes Care
, vol.28
, pp. 1092-1100
-
-
DeFronzo, R.A.1
Ratner, R.E.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
34
-
-
17144371646
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
-
Kendall DM, Riddle MC, Rosenstock J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 2005; 28:1083-1091.
-
(2005)
Diabetes Care
, vol.28
, pp. 1083-1091
-
-
Kendall, D.M.1
Riddle, M.C.2
Rosenstock, J.3
-
35
-
-
34247259577
-
The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial
-
Zinman B, Hoogwerf BJ, Durán García S, et al. The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial. Ann Intern Med 2007; 146:477-485.
-
(2007)
Ann Intern Med
, vol.146
, pp. 477-485
-
-
Zinman, B.1
Hoogwerf, B.J.2
Durán García, S.3
-
36
-
-
27744541052
-
Exenatide augments first-and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
-
Fehse F, Trautmann M, Holst JJ, et al. Exenatide augments first-and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 2005; 90:5991-5997.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 5991-5997
-
-
Fehse, F.1
Trautmann, M.2
Holst, J.J.3
-
37
-
-
0035340019
-
Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro
-
Parkes DG, Pittner R, Jodka C, Smith P, Young A. Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro. Metabolism 2001; 50:583-589.
-
(2001)
Metabolism
, vol.50
, pp. 583-589
-
-
Parkes, D.G.1
Pittner, R.2
Jodka, C.3
Smith, P.4
Young, A.5
-
38
-
-
56549107405
-
Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes
-
Linnebjerg H, Park S, Kothare PA, et al. Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes. Regul Pept 2008; 151:123-129.
-
(2008)
Regul Pept
, vol.151
, pp. 123-129
-
-
Linnebjerg, H.1
Park, S.2
Kothare, P.A.3
-
39
-
-
45549101449
-
Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes
-
Cervera A, Wajcberg E, Sriwijitkamol A, et al. Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes. Am J Physiol Endocrinol Metab 2008; 294:E846-E852.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Cervera, A.1
Wajcberg, E.2
Sriwijitkamol, A.3
-
41
-
-
34249891874
-
Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes
-
Kim D, MacConell L, Zhuang D, et al. Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes. Diabetes Care 2007; 30:1487-1493.
-
(2007)
Diabetes Care
, vol.30
, pp. 1487-1493
-
-
Kim, D.1
MacConell, L.2
Zhuang, D.3
-
42
-
-
53249142132
-
Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study
-
Drucker DJ, Buse JB, Taylor K, et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 2008; 372:1240-1250.
-
(2008)
Lancet
, vol.372
, pp. 1240-1250
-
-
Drucker, D.J.1
Buse, J.B.2
Taylor, K.3
-
43
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
Knudsen LB, Nielsen PF, Huusfeldt PO, et al. Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J Med Chem 2000; 43:1664-1669.
-
(2000)
J Med Chem
, vol.43
, pp. 1664-1669
-
-
Knudsen, L.B.1
Nielsen, P.F.2
Huusfeldt, P.O.3
-
44
-
-
62449169287
-
Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study
-
for the LEAD-2 Study Group
-
Nauck M, Frid A, Hermansen K, et al; for the LEAD-2 Study Group. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study. Diabetes Care 2009; 32:84-90.
-
(2009)
Diabetes Care
, vol.32
, pp. 84-90
-
-
Nauck, M.1
Frid, A.2
Hermansen, K.3
-
45
-
-
74249116605
-
-
Committee for Medicinal Products for Human Use: Summary of Positive Opinion for Victoza. European Medicines Agency Web site Published April 23, 2009. Accessed September 21
-
Committee for Medicinal Products for Human Use: Summary of Positive Opinion for Victoza. European Medicines Agency Web site. http://www.emea.europa.eu/pdfs/human/opinion/Victoza_14168909 en.pdf. Published April 23, 2009. Accessed September 21, 2009.
-
(2009)
-
-
-
46
-
-
59449101432
-
Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial
-
Garber A, Henry R, Ratner R, et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial. Lancet 2009; 373:473-481.
-
(2009)
Lancet
, vol.373
, pp. 473-481
-
-
Garber, A.1
Henry, R.2
Ratner, R.3
-
47
-
-
62449129181
-
Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU)
-
Marre M, Shaw J, Brändle M, et al. Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU). Diabet Med 2009; 26:268-278.
-
(2009)
Diabet Med
, vol.26
, pp. 268-278
-
-
Marre, M.1
Shaw, J.2
Brändle, M.3
-
48
-
-
33845472504
-
Effect of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy on glycemic control in patients with type 2 diabetes
-
for the Sitagliptin 021 Study Group
-
Aschner P, Kipnes MS, Lunceford JK, et al; for the Sitagliptin 021 Study Group. Effect of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy on glycemic control in patients with type 2 diabetes. Diabetes Care 2006; 29:2632-2637.
-
(2006)
Diabetes Care
, vol.29
, pp. 2632-2637
-
-
Aschner, P.1
Kipnes, M.S.2
Lunceford, J.K.3
-
49
-
-
33845476757
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone
-
for the Sitagliptin Study 020 Group
-
Charbonnel B, Karasik A, Liu J, Wu M, Meininger G; for the Sitagliptin Study 020 Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone. Diabetes Care 2006; 29:2638-2643.
-
(2006)
Diabetes Care
, vol.29
, pp. 2638-2643
-
-
Charbonnel, B.1
Karasik, A.2
Liu, J.3
Wu, M.4
Meininger, G.5
-
50
-
-
33845489598
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus
-
Raz I, Hanefeld M, Xu L, et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus. Diabetologia 2006; 49:2564-2571.
-
(2006)
Diabetologia
, vol.49
, pp. 2564-2571
-
-
Raz, I.1
Hanefeld, M.2
Xu, L.3
-
51
-
-
33751557143
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study
-
for the Sitagliptin Study 019 Group
-
Rosenstock J, Brazg R, Andryuk PJ, Lu K, Stein P; for the Sitagliptin Study 019 Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Clin Ther 2006; 28:1556-1568.
-
(2006)
Clin Ther
, vol.28
, pp. 1556-1568
-
-
Rosenstock, J.1
Brazg, R.2
Andryuk, P.J.3
Lu, K.4
Stein, P.5
-
52
-
-
55549136417
-
Effects of exenatide versus sitagliptin on post-prandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study
-
DeFronzo RA, Okerson T, Viswanathan P, Guan X, Holcombe JH, MacConell L. Effects of exenatide versus sitagliptin on post-prandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study. Curr Med Res Opin 2008; 24:2943-2952.
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 2943-2952
-
-
DeFronzo, R.A.1
Okerson, T.2
Viswanathan, P.3
Guan, X.4
Holcombe, J.H.5
MacConell, L.6
-
53
-
-
28844482322
-
Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses
-
Herman GA, Stevens C, Van Dyck K, et al. Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses. Clin Pharmacol Ther 2005; 78:675-688.
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 675-688
-
-
Herman, G.A.1
Stevens, C.2
Van Dyck, K.3
-
54
-
-
77951589773
-
ADA 2008 incretin-based therapeutics
-
MedscapeCME Web site Accessed September 18
-
Baggio LL, Drucker DJ, Maida A, Lamont BJ. ADA 2008: incretin-based therapeutics. MedscapeCME Web site. http://www.medscape.com/viewprogram/15786. Accessed September 18, 2009.
-
(2009)
-
-
Baggio, L.L.1
Drucker, D.J.2
Maida, A.3
Lamont, B.J.4
-
55
-
-
74249115055
-
-
US Department of Health and Human Services US Food and Drug Administration Web site Published July 31, 2009. Accessed September 18
-
US Department of Health and Human Services. FDA approves new drug treatment for type 2 diabetes. US Food and Drug Administration Web site. http://www.fda.gov/newsevents/newsroom/pressannouncements/ucm174780.htm. Published July 31, 2009. Accessed September 18, 2009.
-
(2009)
FDA approves new drug treatment for type 2 diabetes
-
-
-
56
-
-
41649083174
-
Pharmacokinetic, pharmacodynamic, and tolerability profiles of the dipeptidyl peptidase-4 inhibitor alogliptin: a randomized, double-blind, placebo-controlled, multiple-dose study in adult patients with type 2 diabetes
-
Covington P, Christopher R, Davenport M, et al. Pharmacokinetic, pharmacodynamic, and tolerability profiles of the dipeptidyl peptidase-4 inhibitor alogliptin: a randomized, double-blind, placebo-controlled, multiple-dose study in adult patients with type 2 diabetes. Clin Ther 2008; 30:499-512.
-
(2008)
Clin Ther
, vol.30
, pp. 499-512
-
-
Covington, P.1
Christopher, R.2
Davenport, M.3
-
57
-
-
58149171060
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes and inadequate glycemic control: a randomized, double-blind, placebo-controlled study
-
on behalf of the Alogliptin Study 010 Group
-
DeFronzo RA, Fleck PR, Wilson CA, Mekki Q; on behalf of the Alogliptin Study 010 Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes and inadequate glycemic control: a randomized, double-blind, placebo-controlled study. Diabetes Care 2008; 31:2315-2317.
-
(2008)
Diabetes Care
, vol.31
, pp. 2315-2317
-
-
DeFronzo, R.A.1
Fleck, P.R.2
Wilson, C.A.3
Mekki, Q.4
-
58
-
-
41949084607
-
The changing landscape of type 2 diabetes: the role of incretin-based therapies in managed care outcomes
-
Triplitt CL, McGill JB, Porte D Jr, Conner CS. The changing landscape of type 2 diabetes: the role of incretin-based therapies in managed care outcomes. J Manag Care Pharm 2007; 13(9 suppl C):S2-S16.
-
(2007)
J Manag Care Pharm
, vol.13
, Issue.9 SUPPL. C
-
-
Triplitt, C.L.1
McGill, J.B.2
Porte D., Jr.3
Conner, C.S.4
-
59
-
-
51949116060
-
An overview of incretin clinical trials
-
Garber AJ, Spann SJ. An overview of incretin clinical trials. J Fam Pract 2008; 57(9 suppl):S10-S18.
-
(2008)
J Fam Pract
, vol.57
, Issue.9 SUPPL.
-
-
Garber, A.J.1
Spann, S.J.2
-
60
-
-
50149089590
-
Evolving concepts of type 2 diabetes management with oral medications: new approaches to an old disease
-
Henry RR. Evolving concepts of type 2 diabetes management with oral medications: new approaches to an old disease. Curr Med Res Opin 2008; 24:2189-2202.
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 2189-2202
-
-
Henry, R.R.1
-
61
-
-
54049148081
-
-
Centers for Disease Control and Prevention Centers for Disease Control and Prevention Web site Published 2008. Accessed September 21
-
Centers for Disease Control and Prevention. National diabetes fact sheet: general information and national estimates on diabetes in the United States, 2007. Centers for Disease Control and Prevention Web site. http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2007.pdf. Published 2008. Accessed September 21, 2009.
-
(2009)
National diabetes fact sheet: general information and national estimates on diabetes in the United States, 2007
-
-
-
62
-
-
39149145482
-
Prevalence, treatment, and control of diagnosed diabetes in the U.S. National Health and Nutrition Examination Survey 1999-2004
-
Ong KL, Cheung BM, Wong LY, Wt NM, Tan KC, Lam KS. Prevalence, treatment, and control of diagnosed diabetes in the U.S. National Health and Nutrition Examination Survey 1999-2004. Ann Epidemiol 2008; 18:222-229.
-
(2008)
Ann Epidemiol
, vol.18
, pp. 222-229
-
-
Ong, K.L.1
Cheung, B.M.2
Wong, L.Y.3
Wt, N.M.4
Tan, K.C.5
Lam, K.S.6
-
64
-
-
1042280201
-
Glycemic control from 1988 to 2000 among US adults diagnosed with type 2 diabetes: a preliminary report
-
Koro CE, Bowlin SJ, Bourgeois N, Fedder DO. Glycemic control from 1988 to 2000 among US adults diagnosed with type 2 diabetes: a preliminary report. Diabetes Care 2004; 27:17-20.
-
(2004)
Diabetes Care
, vol.27
, pp. 17-20
-
-
Koro, C.E.1
Bowlin, S.J.2
Bourgeois, N.3
Fedder, D.O.4
-
65
-
-
0032560807
-
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
-
Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998; 339:229-234.
-
(1998)
N Engl J Med
, vol.339
, pp. 229-234
-
-
Haffner, S.M.1
Lehto, S.2
Rönnemaa, T.3
Pyörälä, K.4
Laakso, M.5
-
66
-
-
60449094498
-
Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
-
Lloyd-Jones D, Adams R, Carnethon M, et al. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009; 119:480-486.
-
(2009)
Circulation
, vol.119
, pp. 480-486
-
-
Lloyd-Jones, D.1
Adams, R.2
Carnethon, M.3
-
67
-
-
74249123740
-
GLP-1 analogues, DPP-IV inhibitors and the metabolic syndrome
-
Fonseca V, ed. Oxford, UK: Atlas Medical Publishing Ltd;
-
Stonehouse AH, Holcombe JH, Kendall DM. GLP-1 analogues, DPP-IV inhibitors and the metabolic syndrome. In: Fonseca V, ed. Therapeutic Strategies in Metabolic Syndrome. Oxford, UK: Atlas Medical Publishing Ltd; 2008: 137-157.
-
(2008)
Therapeutic Strategies in Metabolic Syndrome
, pp. 137-157
-
-
Stonehouse, A.H.1
Holcombe, J.H.2
Kendall, D.M.3
-
68
-
-
0042861368
-
Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesity
-
Purnell JQ, Weyer C. Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesity. Treat Endocrinol 2003; 2:33-47.
-
(2003)
Treat Endocrinol
, vol.2
, pp. 33-47
-
-
Purnell, J.Q.1
Weyer, C.2
-
69
-
-
38549162147
-
Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
-
Klonoff DC, Buse JB, Nielsen LL, et al. Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years. Curr Med Res Opin 2008; 24:275-286.
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 275-286
-
-
Klonoff, D.C.1
Buse, J.B.2
Nielsen, L.L.3
-
70
-
-
37349008890
-
Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover non-inferiority trial
-
Barnett AH, Burger J, Johns D, et al. Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover non-inferiority trial. Clin Ther 2007; 29:2333-2348.
-
(2007)
Clin Ther
, vol.29
, pp. 2333-2348
-
-
Barnett, A.H.1
Burger, J.2
Johns, D.3
-
71
-
-
41149104495
-
Effects of exenatide versus insulin analogues on weight change in subjects with type 2 diabetes: a pooled post-hoc analysis
-
Glass LC, Qu Y, Lenox S, et al. Effects of exenatide versus insulin analogues on weight change in subjects with type 2 diabetes: a pooled post-hoc analysis. Curr Med Res Opin 2008; 24:639-644.
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 639-644
-
-
Glass, L.C.1
Qu, Y.2
Lenox, S.3
-
72
-
-
26944477362
-
Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial
-
for the GWAA Study Group
-
Heine RJ, Van Gaal LF, Johns D, Mihm MJ, Widel MH, Brodows RG; for the GWAA Study Group. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial. Ann Intern Med 2005; 143:559-569.
-
(2005)
Ann Intern Med
, vol.143
, pp. 559-569
-
-
Heine, R.J.1
Van Gaal, L.F.2
Johns, D.3
Mihm, M.J.4
Widel, M.H.5
Brodows, R.G.6
-
73
-
-
34247195226
-
A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study
-
Nauck MA, Duran S, Kim D, et al. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study. Diabetologia 2007; 50:259-267.
-
(2007)
Diabetologia
, vol.50
, pp. 259-267
-
-
Nauck, M.A.1
Duran, S.2
Kim, D.3
-
74
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagonlike peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways
-
Ban K, Noyan-Ashraf MH, Hoefer J, Bolz SS, Drucker DJ, Husain M. Cardioprotective and vasodilatory actions of glucagonlike peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation 2008; 117:2340-2350.
-
(2008)
Circulation
, vol.117
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
Bolz, S.S.4
Drucker, D.J.5
Husain, M.6
-
75
-
-
1442311383
-
Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion
-
Nikolaidis LA, Mankad S, Sokos GG, et al. Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation 2004; 109:962-965.
-
(2004)
Circulation
, vol.109
, pp. 962-965
-
-
Nikolaidis, L.A.1
Mankad, S.2
Sokos, G.G.3
|