In vitro cytotoxic effects of benzalkonium chloride on adenovirus

Eye and Contact Lens

Volumn 35, Issue 6, 2009, Pages 329-332

  Lazzaro, Douglas R ^a   Abulawi, Khaled ^a,b   Hajee, Mohammedyusuf E ^a  

^a KINGS COUNTY HOSPITAL CENTER   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

Adenovirus; BAK; Gatifloxacin; Immunofluorescence

Indexed keywords

BENZALKONIUM CHLORIDE; GATIFLOXACIN;

ADENOVIRUS; ADENOVIRUS INFECTION; ARTICLE; CELL SURVIVAL; CYTOLYSIS; CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; VIRUS LOAD;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; BENZALKONIUM COMPOUNDS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; MICROBIAL SENSITIVITY TESTS; PRESERVATIVES, PHARMACEUTICAL;

EID: 74249114770     PISSN: 15422321     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICL.0b013e3181c1060a     Document Type: Article

References (11)

1. Belec L, Tevi-Benissan C, Bianchi A, et al. In vitro inactivation of Chlamydia trachomatis and of a panel of DNA (HSV-2, CMV, adenovirus, BK virus) and RNA (RSV, enterovirus) viruses by the spermacide benzalkonium chloride. J Antimicrob Chemother 2000;46:685-693.
2. Kawana R, Kitamura T, Nakagomi O, et al. Inactivation of human viruses by povidone-iodine in comparison with other antiseptics. Dermatology 1997;195 (Suppl 2):29-35.
3. Tripathi BJ, Tripathi RC. Cytotoxicity of ophthalmic preservatives on human corneal epithelium. Lens Eye toxic Res 1992;9:361-375.
4. Noecker R. Effects of common ophthalmic preservatives on ocular health. Adv Ther 2001;18:205-215.
5. Lemp MA, Zimmerman ME. Toxic endothelial degeneration in ocular surface disease treated with topical medications containing benzalkonium chloride. Am J Ophthalmol 1988;105:670-673.
6. Furrer P, Mayer JM, Plazonnet B, et al. Ocular tolerance of preservatives on the murine cornea. Eur J Pharm Biopharm 1999;57:105-112.
7. Ichijima H, Petroll WM, Jester JV, et al. Confocal microscopic studies of living rabbit cornea treated with benzalkonium chloride. Cornea 1992;11: 221-225.
8. Samples JR, Binder PS, Nayak S. The effects of epinephrine and benzalkonium chloride on cultured corneal endothelial and trabecular meshwork cells. Exp Eye Res 1989;49:1-12.
9. Ford E, Nelson KE, Warren D. Epidemiology of epidemic keratoconjunctivitis. Epidemiol Rev 1987;9:244-259.
10. Armstrong JA, Froelich EJ. Inactivation of viruses by benzalkonium chloride. Appl Microbiol 1964;12:132-137.
11. Taylor-Robinson D, Ballard RC. In vitro inactivation of Chlamydia trachomatis and of a panel of DNA (HSV-2, CMV, adenovirus, BK virus) and RNA (RSV, enterovirus) viruses by the spermicide benzalkonium chloride. J Antimicrob Chemother 2001;47:721-722.