Phytochemical and anti-ulcer investigations of the whole plant extract of Neregamia alata Wight & Arn. in albino rat model

Pharmacognosy Magazine

Volumn 5, Issue 19 SUPPL., 2009, Pages 19-22

  Purushothaman, M ^a   Dhanapal, R ^b   Balakrishnan, M ^c   Srinivasan, S ^d   Anbarasu, C ^e   Sriram, R ^b  

^a Department of Pharmaceutics   (India)

^b ST PETER'S INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

^c Vagdevi College of Pharmacy   (India)

^d Maharajah's College of Pharmacy   (India)

^e Strides Arcolab Limited   (India)

Author keywords

Anti ulcerogenic; Hypothermic restraint stress; MENA; Neregamia alata; Pyloric ligation

Indexed keywords

ANTIULCER AGENT; FAMOTIDINE; METHANOL; NEREGAMIA ALATA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; FEMALE; HYPOTHERMIA; IMMOBILIZATION STRESS; MALE; MEDICINAL PLANT; NEREGAMIA ALATA; NONHUMAN; PHYTOCHEMISTRY; PYLORUS LIGATION; RAT; STOMACH ULCER; STRESS ULCER; TREATMENT OUTCOME;

EID: 74249112225     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Warrier P.K., Nambiar V.P., Ramankutty C. Indian medicinal plants a compendium of 500 species. Vol-1 Orient Longman Pvt Ltd. pp 10-14 (1993).
2. Khare C. P. Encyclopedia of Indian Medicinal plants: Rational Western Therapy, Ayurvedic and other traditional Usage Botany. Berlin, New York. Springer. pp. 3-5 (2004).
3. Plummer D.I. An Introduction to Practical Biochemistry, ed 2, Tata Magraw-Hill Publishing Co. Ltd., New Delhi. pp 136,143(1985).
4. Pollock J.R.A. and Stevens R.. Editors. Dictionary of Organic Compounds, vol.-5, ed 4, London, Eyre and Spottiswoode. (1965).
5. Trease G.E. and Evans W.C. Pharmacognosy, Ed 12, (ELBS Publication, Baillier Tindall, East Bourne) pp 344, 539(1996).
6. Tyler V.E., Brady L.R. and Robbers J.E. Pharmacognosy, 9th 9. Philadelphia, PA: Lea and Febiger. Botanical medicine: efficacy, quality assurance, and regulation. New York Mary Ann Liebert, pp59-64 (1993).
7. Shay H., Kamorow S.A., Fele S.S., Meranz D., Gruenstein H. and Siplet H. Gastroenterology. 5: 43(1945).
8. Levine R.J.. A method for rapid production of stress ulcers in rats. In: Pfeiffer C.J. (Ed.), Peptic Ulcer. Munksgaard, Copenhagen,: pp 92-97(1971).
9. Toma W., Hiruma-Lima C.A., Guerrero R.O. and Souza Brito A.R.M.. Preliminary studies of Mammea americana L. (Guttiferae) bark/latex extract point to an effective antiulcer effect on gastric ulcer models in mice. Phytomedicine. 12(5):345-350(2005).
10. Goel R.K. and Bhattacharya S.K. Gastroduodenal mucosal defense and mucosal protective agents. Indian Journal of Experimental Biology. 29: 701-714(1991).
11. Satyanarayana S., Kumar Prasanna and Viswesaram D. Antiulcer activity of Agni tundirasa and its comparison with Cimetidine in Shay rat. Ancient Science of Life. 3:207-211(1980).
12. Ram P., Rastogi B.N., Mehrotra. Compendium of Indian Medicinal Plants. Volume I, :pp228(1960-1969).
13. Baggio C.H., Freitas C.S., Rieck L. and Margues M.C.A. Gastroprotective effects of a crude extract of Baccharis illinita DC in rats, Pharmacological Research. 47: 93-98(2003).
14. Cho C.H., Ogle C.W. and Dai S. Acute gastric ulcer formation response to electrical vagal stimulation in rats. European Journal of Pharmacology. 35: 215-219(1976).
15. 2-receptor activation in stress ulceration in rats. European Journal of Pharmacology. 55: 23-33(1979).
16. Hase T. and Moss B.J. Microvascular changes of gastric mucosa in the development of stress ulcer in rats. Gastroenterology. 65: 224-234(1973).
17. Singh S. and Majumdar D.K. Evaluation of the gastric activity of fixed oil of Ocimum sanctum (Holy Basil). Journal of Ethnopharmacology. 65:13-19(1999).