Effect of menses on clearance of Y-chromosome in vaginal fluid: Implications for a biomarker of recent sexual activity

Sexually Transmitted Diseases

Volumn 37, Issue 1, 2010, Pages 1-4

  Brotman, Rebecca M ^a   Melendez, Johan H ^b   Smith, Tukisa D ^b   Galai, Noya ^c,d   Zenilman, Jonathan M ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BAYVIEW MEDICAL CENTER   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF HAIFA   (Israel)

Author keywords

Biomarker; Sexually transmitted infection; Y chromosome

Indexed keywords

BIOLOGICAL MARKER; DNA;

ARTICLE; COITUS; DNA EXTRACTION; HUMAN; MENSTRUATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEXUAL BEHAVIOR; SEXUAL INTERCOURSE; SEXUALLY TRANSMITTED DISEASE; VAGINA DISCHARGE; Y CHROMOSOME;

ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, Y; COITUS; FEMALE; HUMANS; MENSTRUATION; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEXUALLY TRANSMITTED DISEASES; VAGINA; VAGINAL SMEARS;

EID: 74249112132     PISSN: 01485717     EISSN: None     Source Type: Journal    
DOI: 10.1097/OLQ.0b013e3181b5f15d     Document Type: Article

References (14)

1. Mauck CK, Doncel GF. Biomarkers of semen in the vagina: Applications in clinical trials of contraception and prevention of sexually transmitted pathogens including HIV. Contraception 2007; 75:407-419.
2. Zenilman JM, Weisman CS, Rompalo AM, et al. Condom use to prevent incident STDs: The validity of self-reported condom use. Sex Transm Dis 1995; 22:15-21.
3. Pequegnat W, Fishbein M, Celentano D, et al. NIMH/APPC workgroup on behavioral and biological outcomes in HIV/STD prevention studies: A position statement. Sex Transm Dis 2000; 27:127-132.
4. Macaluso M, Lawson L, Akers R, et al. Prostate-specific antigen in vaginal fluid as a biologic marker of condom failure. Contraception 1999; 59:195-201.
5. Warner L, Macaluso M, Austin HD, et al. Application of the case-crossover design to reduce unmeasured confounding in studies of condom effectiveness. Am J Epidemiol 2005; 161: 765-773.
6. Ghanem KG, Melendez JH, Neil-Solis C, et al. Condom use and vaginal Y-chromosome detection: The specificity of a potential biomarker. Sex Transm Dis 2007; 34:620-623.
7. Melendez JH, Giles JA, Yuenger JD, et al. Detection and quantification of Y-chromosomal sequences by real-time PCR using the LightCycler system. Sex Transm Dis 2007; 34:617-619.
8. Zenilman JM, Yuenger J, Galai N, et al. Polymerase chain reaction detection of Y chromosome sequences in vaginal fluid: Preliminary studies of a potential biomarker for sexual behavior. Sex Transm Dis 2005; 32:90-94.
9. van de WJ, Altini L, Jones H, et al. Two methods of self-sampling compared to clinician sampling to detect reproductive tract infections in Gugulethu, South Africa. Sex Transm Dis 2006; 33:516-523.
10. Boskey ER, Atherly-Trim SA, O'Campo PJ, et al. Acceptability ofa self-sampling technique to collect vaginal smears for gram stain diagnosis of bacterial vaginosis. Womens Health Issues 2004; 14:14-18.
11. Mayntz-Press KA, Sims LM, Hall A, et al. Y-STR profiling in extended interval (or = 3 days) postcoital cervicovaginal samples. J Forensic Sci 2008; 53:342-348.
12. Brotman RM, Klebanoff MA, Nansel T, et al. Why do women douche? A longitudinal study with two analytic approaches. Ann Epidemiol 2008; 18:65-73.
13. Foxman B, Aral SO, Holmes KK. Interrelationships among douching practices, risky sexual practices, and history of self-reported sexually transmitted diseases in an urban population. Sex Transm Dis 1998; 25:90-99.
14. Scholes D, Stergachis A, Ichikawa LE, et al. Vaginal douching as a risk factor for cervical Chlamydia trachomatis infection. Obstet Gynecol 1998; 91:993-997.