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Volumn 103, Issue 1, 2010, Pages 34-39

The clinical implications of new oral anticoagulants: Will the potential advantages be achieved?

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTIVITAMIN K; APIXABAN; DABIGATRAN ETEXILATE; ENOXAPARIN; FONDAPARINUX; GLYCOPROTEIN P INHIBITOR; LOW MOLECULAR WEIGHT HEPARIN; PLACEBO; PROTON PUMP INHIBITOR; RIVAROXABAN; WARFARIN; XIMELAGATRAN;

EID: 74249107395     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH09-06-0361     Document Type: Review
Times cited : (41)

References (37)
  • 1
    • 45949103309 scopus 로고    scopus 로고
    • The pharmacology and management of the vitamin K antagonists: ACCP evidence-based clinical practice guidelines
    • Ansell, J, et al. The pharmacology and management of the vitamin K antagonists: ACCP evidence-based clinical practice guidelines. Chest 2008; 133: 160S-198S.
    • (2008) Chest , vol.133
    • Ansell, J.1
  • 2
    • 33750106228 scopus 로고    scopus 로고
    • National surveillance of emergency department visits for outpatient adverse drug events
    • Budnitz DS, et al. National surveillance of emergency department visits for outpatient adverse drug events. J Am Med Assoc 2006; 296: 1858-1866.
    • (2006) J Am Med Assoc , vol.296 , pp. 1858-1866
    • Budnitz, D.S.1
  • 4
    • 45949083155 scopus 로고    scopus 로고
    • New Antithrombotic Drugs
    • Weitz JI, et al. New Antithrombotic Drugs. Chest 2008; 133: 234S-256S.
    • (2008) Chest , vol.133
    • Weitz, J.I.1
  • 5
    • 57449094606 scopus 로고    scopus 로고
    • Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Developtment
    • Eriksson BI, et al. Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Developtment. Clin Pharmacokinet 2009; 48: 1-22.
    • (2009) Clin Pharmacokinet , vol.48 , pp. 1-22
    • Eriksson, B.I.1
  • 6
    • 34447317298 scopus 로고    scopus 로고
    • ODIXa-DVT Study Investigators. Treatment of proximal deep-vein thrombosis with the oral direct factor Xa inhibitor rivaroxaban (BAY 59-7939): The ODIXa-DVT (Oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients With Acute Symptomatic Deep-Vein Thrombosis) study
    • Agnelli G, et al. ODIXa-DVT Study Investigators. Treatment of proximal deep-vein thrombosis with the oral direct factor Xa inhibitor rivaroxaban (BAY 59-7939): the ODIXa-DVT (Oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients With Acute Symptomatic Deep-Vein Thrombosis) study. Circulation 2007; 116: 180-187.
    • (2007) Circulation , vol.116 , pp. 180-187
    • Agnelli, G.1
  • 7
    • 55249093117 scopus 로고    scopus 로고
    • Brave new world: The current and future use of novel anticoagulants
    • Spyropoulos AC. Brave new world: The current and future use of novel anticoagulants. Thromb Res 2008; 123: 29-35.
    • (2008) Thromb Res , vol.123 , pp. 29-35
    • Spyropoulos, A.C.1
  • 8
    • 0345414673 scopus 로고    scopus 로고
    • Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): Randomized controlled trial
    • Executive Steering Committee on behalf of the SPORTIF III Investigators
    • Executive Steering Committee on behalf of the SPORTIF III Investigators. Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomized controlled trial. Lancet 2003; 362: 1691-1698.
    • (2003) Lancet , vol.362 , pp. 1691-1698
  • 9
    • 13444309949 scopus 로고    scopus 로고
    • Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: A randomized trial
    • SPORTIF Executive Steering Committee for the SPORTIF V Investigators
    • SPORTIF Executive Steering Committee for the SPORTIF V Investigators. Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a randomized trial. J Am Med Assoc 2005; 293: 690-698.
    • (2005) J Am Med Assoc , vol.293 , pp. 690-698
  • 10
    • 13444278653 scopus 로고    scopus 로고
    • Ximelagatran vs low-molecular-weight heparin and warfarin for the treatment of deep vein thrombosis: A randomized trial
    • Fiessinger JN, et al. Ximelagatran vs low-molecular-weight heparin and warfarin for the treatment of deep vein thrombosis: a randomized trial. J Am Med Assoc 2005; 293: 681-689.
    • (2005) J Am Med Assoc , vol.293 , pp. 681-689
    • Fiessinger, J.N.1
  • 11
    • 0041829444 scopus 로고    scopus 로고
    • Oral ximelagatran for secondary prophylaxis after myocardial infarction: The ES-TEEM randomized controlled trial
    • Wallentin L, et al. Oral ximelagatran for secondary prophylaxis after myocardial infarction: the ES-TEEM randomized controlled trial. Lancet 2003; 362: 789-797.
    • (2003) Lancet , vol.362 , pp. 789-797
    • Wallentin, L.1
  • 12
    • 35449007749 scopus 로고    scopus 로고
    • Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: The RE-MODEL randomized trial
    • RE-MODEL Study Group
    • RE-MODEL Study Group: Eriksson BI, Dahl OE, Rosencher N, et al. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial. J Thromb Haemost 2007; 5: 2178-2185.
    • (2007) J Thromb Haemost , vol.5 , pp. 2178-2185
    • Eriksson, B.I.1    Dahl, O.E.2    Rosencher, N.3
  • 13
    • 34548575058 scopus 로고    scopus 로고
    • Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomized, double-blind, non-inferiority trial
    • RE-NOVATE Study Group
    • RE-NOVATE Study Group: Eriksson BI, Dahl OE, Rosencher N, et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomized, double-blind, non-inferiority trial. Lancet 2007; 370: 949-956.
    • (2007) Lancet , vol.370 , pp. 949-956
    • Eriksson, B.I.1    Dahl, O.E.2    Rosencher, N.3
  • 14
    • 57649123692 scopus 로고    scopus 로고
    • Oral thrombin inhibitor Dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery
    • RE-MOBILIZE Writing Committee
    • RE-MOBILIZE Writing Committee: Ginsberg JS, Davidson BL, Comp PC, et al. Oral thrombin inhibitor Dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery. J Arthroplasty 2009; 24: 1-9.
    • (2009) J Arthroplasty , vol.24 , pp. 1-9
    • Ginsberg, J.S.1    Davidson, B.L.2    Comp, P.C.3
  • 15
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation
    • Connolly SJ, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361: 1139-1151
    • (2009) N Engl J Med , vol.361 , pp. 1139-1151
    • Connolly, S.J.1
  • 16
    • 45949099359 scopus 로고    scopus 로고
    • Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty
    • RECORD1 Study Group
    • RECORD1 Study Group: Eriksson BI, Borris LC, Friedman RJ, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med 2008; 358: 2765-2775.
    • (2008) N Engl J Med , vol.358 , pp. 2765-2775
    • Eriksson, B.I.1    Borris, L.C.2    Friedman, R.J.3
  • 17
    • 46049106502 scopus 로고    scopus 로고
    • Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: A double-blind, randomized controlled trial
    • RECORD2 Investigators
    • RECORD2 Investigators: Kakkar AK, Brenner B, Dahl OE, et al. Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomized controlled trial. Lancet 2008; 372: 31-39.
    • (2008) Lancet , vol.372 , pp. 31-39
    • Kakkar, A.K.1    Brenner, B.2    Dahl, O.E.3
  • 18
    • 45949103416 scopus 로고    scopus 로고
    • Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
    • RECORD3 Investigators
    • RECORD3 Investigators: Lassen MR, Ageno W, Borris LC, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008; 358: 2776-2786.
    • (2008) N Engl J Med , vol.358 , pp. 2776-2786
    • Lassen, M.R.1    Ageno, W.2    Borris, L.C.3
  • 19
    • 65549169515 scopus 로고    scopus 로고
    • Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD 4): A randomized trial
    • Turpie AGG, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD 4): a randomized trial. Lancet 2009; 373: 1673-1680.
    • (2009) Lancet , vol.373 , pp. 1673-1680
    • Turpie, A.G.G.1
  • 20
    • 74249086516 scopus 로고    scopus 로고
    • Turpie AGG, et al. A pooled analysis of four pivotal studies of rivaroxaban for the prevention of venous thromboembolism after orthopedic surgery: effect on symptomatic venous thromboembolism, death, and bleeding. Blood (ASH Annual Meeting Abstracts) 2008; 112: 18-19 (Abstract 36).
    • Turpie AGG, et al. A pooled analysis of four pivotal studies of rivaroxaban for the prevention of venous thromboembolism after orthopedic surgery: effect on symptomatic venous thromboembolism, death, and bleeding. Blood (ASH Annual Meeting Abstracts) 2008; 112: 18-19 (Abstract 36).
  • 21
    • 68249158084 scopus 로고    scopus 로고
    • Apixaban or enoxaparin for thromboprophylaxis after knee replacement
    • Lassen M, et al. Apixaban or enoxaparin for thromboprophylaxis after knee replacement. N Engl J Med 2009; 361: 594-604.
    • (2009) N Engl J Med , vol.361 , pp. 594-604
    • Lassen, M.1
  • 22
    • 74249102000 scopus 로고    scopus 로고
    • The ADVANCE 2 study: A randomized double-blind trial comparing apixaban with enoxaparin for thromboprophylaxis after total knee replacement
    • Abstract #LB-MO-005
    • Lassen MR, et al. The ADVANCE 2 study: A randomized double-blind trial comparing apixaban with enoxaparin for thromboprophylaxis after total knee replacement. J Thromb Haemost 2009; 7 (Suppl. 2): Abstract #LB-MO-005.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 2
    • Lassen, M.R.1
  • 23
    • 38749131205 scopus 로고    scopus 로고
    • The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
    • Blech S, et al. The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metab Dispos 2008; 36: 386-399.
    • (2008) Drug Metab Dispos , vol.36 , pp. 386-399
    • Blech, S.1
  • 24
    • 29144518504 scopus 로고    scopus 로고
    • Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939- an oral, direct Factor Xa inhibitor- after multiple dosing in healthy male subjects
    • Kubitza D, et al. Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939- an oral, direct Factor Xa inhibitor- after multiple dosing in healthy male subjects. Eur J Clin Pharmacol 2005; 61: 873-880.
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 873-880
    • Kubitza, D.1
  • 25
    • 33748590510 scopus 로고    scopus 로고
    • Emerging anticoagulants for the treatment of venous thromboembolism
    • Weitz JI. Emerging anticoagulants for the treatment of venous thromboembolism. Thromb Haemost 2006; 96: 274-284.
    • (2006) Thromb Haemost , vol.96 , pp. 274-284
    • Weitz, J.I.1
  • 26
    • 34548031359 scopus 로고    scopus 로고
    • The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
    • Stangier J, et al. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol 2007; 64: 292-303.
    • (2007) Br J Clin Pharmacol , vol.64 , pp. 292-303
    • Stangier, J.1
  • 27
    • 50249129715 scopus 로고    scopus 로고
    • Apixaban, an oral, direct inhibitor of activated Factor Xa
    • Shantsila E, Lip GY. Apixaban, an oral, direct inhibitor of activated Factor Xa. Curr Opin Investig Drugs 2008; 9: 1020-1033.
    • (2008) Curr Opin Investig Drugs , vol.9 , pp. 1020-1033
    • Shantsila, E.1    Lip, G.Y.2
  • 28
    • 41949116970 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate
    • Stangier J. Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate. Clin Pharmacokinet 2008; 47: 285-295.
    • (2008) Clin Pharmacokinet , vol.47 , pp. 285-295
    • Stangier, J.1
  • 29
    • 40749131754 scopus 로고    scopus 로고
    • New anticoagulants for treatment of venous thromboembolism
    • Gross PL, Weitz JI. New anticoagulants for treatment of venous thromboembolism. Arterioscler Thromb Vasc Biol 2008; 28: 380-386.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 380-386
    • Gross, P.L.1    Weitz, J.I.2
  • 30
    • 0036719562 scopus 로고    scopus 로고
    • Patient adherence and medical treatment outcomes: A meta-analysis
    • DiMatteo MR, et al. Patient adherence and medical treatment outcomes: a meta-analysis. Med Care 2002; 40: 794-811.
    • (2002) Med Care , vol.40 , pp. 794-811
    • DiMatteo, M.R.1
  • 31
    • 0000120805 scopus 로고
    • Partial medication compliance: The enigma in poor medical outcomes
    • Cramer JA. Partial medication compliance: the enigma in poor medical outcomes. Am J Manag Care 1995; 1: 167-174.
    • (1995) Am J Manag Care , vol.1 , pp. 167-174
    • Cramer, J.A.1
  • 32
    • 0002306763 scopus 로고
    • Noncompliance with medication regimens and subsequent hospitalizations: A literature analysis and cost of hospitalization estimate
    • Sullivan SD, et al. Noncompliance with medication regimens and subsequent hospitalizations: a literature analysis and cost of hospitalization estimate. J Res Pharm Econ 1990; 2: 19-33.
    • (1990) J Res Pharm Econ , vol.2 , pp. 19-33
    • Sullivan, S.D.1
  • 33
    • 0033660931 scopus 로고    scopus 로고
    • Adherence in chronic disease
    • New York: Springer
    • Dunbar-Jacob J, et al. Adherence in chronic disease. In : Annual review of nursing research. New York: Springer 2000; 18: pp. 48-90.
    • (2000) Annual review of nursing research , vol.18 , pp. 48-90
    • Dunbar-Jacob, J.1
  • 34
    • 52949151490 scopus 로고    scopus 로고
    • Risk factors for nonadherence to warfarin: Results from the IN-RANGE study
    • Platt AB, et al. Risk factors for nonadherence to warfarin: results from the IN-RANGE study. Pharmcoepidemiology Drug Safety 2008; 17: 853-860.
    • (2008) Pharmcoepidemiology Drug Safety , vol.17 , pp. 853-860
    • Platt, A.B.1
  • 35
    • 0142103759 scopus 로고    scopus 로고
    • Optimizing the Efficacy and Safety of Oral Anticoagulant Therapy: High Quality Dose Management, Anticoagulation Clinics, and Patient Self-Management
    • Ansell JE. Optimizing the Efficacy and Safety of Oral Anticoagulant Therapy: High Quality Dose Management, Anticoagulation Clinics, and Patient Self-Management. Semin Vas Med 2003; 3: 261-269.
    • (2003) Semin Vas Med , vol.3 , pp. 261-269
    • Ansell, J.E.1
  • 36
    • 33846952856 scopus 로고    scopus 로고
    • The Influence of Patient Adherence on Anticoagulation Control with Warfarin : Results from the International Normalized Ratio Adherence and Genetics (IN-RANGE) Study
    • Kimmel SE, et al. The Influence of Patient Adherence on Anticoagulation Control with Warfarin : Results from the International Normalized Ratio Adherence and Genetics (IN-RANGE) Study. Arch Intern Med 2007; 167: 229-235.
    • (2007) Arch Intern Med , vol.167 , pp. 229-235
    • Kimmel, S.E.1
  • 37
    • 74249101768 scopus 로고    scopus 로고
    • Cash-strapped
    • US Patients may be skipping drugs. Reuters. 2/10/09. http://www.reuters.com/article/healthNews/idUSTRE5196SR20090211. Accessed on 2/11/09
    • Fox M, et al. Cash-strapped US Patients may be skipping drugs. Reuters. 2/10/09. http://www.reuters.com/article/healthNews/idUSTRE5196SR20090211. Accessed on 2/11/09.
    • Fox, M.1


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