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Volumn 1217, Issue 7, 2010, Pages 1024-1032
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Extending the use of "Inverted Chirality Columns Approach" for enantiomeric excess determination in absence of reference samples: Application to a water-soluble camptothecin derivative
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Author keywords
Anticancer drugs; Camptothecin (CPT) family; Elution order reversal; Inverted Chirality Columns Approach (ICCA); Namitecan (ST1968)
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Indexed keywords
AMINO GROUP;
ANTI-CANCER AGENTS;
ANTICANCER DRUG;
CAMPTOTHECIN DERIVATIVES;
CAMPTOTHECINS;
CHIRAL RECOGNITION MECHANISMS;
CHIRAL STATIONARY PHASIS;
CHIRALITY COLUMNS;
CLINICAL TRIAL;
ELUTION ORDER;
ENANTIOMERIC EXCESS;
ENANTIOSELECTIVE HPLC;
NORMAL PHASE HPLC;
OPTIMAL COLUMN;
PHASE I;
SULFUR ANALOGUES;
TERMINAL AMINO GROUPS;
BODY FLUIDS;
CHARGE TRAPPING;
ENANTIOMERS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
STEREOCHEMISTRY;
SULFUR;
CHIRALITY;
CAMPTOTHECIN DERIVATIVE;
ISOCYANIC ACID DERIVATIVE;
NAMITECAN;
ST 1968;
SULFUR DERIVATIVE;
UNCLASSIFIED DRUG;
WATER;
ARTICLE;
CHIRALITY;
CONTROLLED STUDY;
DERIVATIZATION;
DRUG IDENTIFICATION;
DRUG STRUCTURE;
ENANTIOMER;
ENANTIOSELECTIVITY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HYDROPHILICITY;
PRIORITY JOURNAL;
QUANTITATIVE ANALYSIS;
TANDEM MASS SPECTROMETRY;
CAMPTOTHECIN;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
ISOCYANATES;
LEAST-SQUARES ANALYSIS;
REPRODUCIBILITY OF RESULTS;
SOLUBILITY;
STEREOISOMERISM;
TANDEM MASS SPECTROMETRY;
WATER;
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EID: 74249106721
PISSN: 00219673
EISSN: None
Source Type: Journal
DOI: 10.1016/j.chroma.2009.10.035 Document Type: Article |
Times cited : (30)
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References (22)
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