메뉴 건너뛰기




Volumn 31, Issue 1, 2010, Pages 55-66

Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: Role of monoamine oxidase enzyme

Author keywords

Dexamethasone; Dopaminergic neurodegeneration; Inflammation; Monoamine oxidase; Substantia nigra

Indexed keywords

ALPHA SYNUCLEIN; AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; DEXAMETHASONE; MITOGEN ACTIVATED PROTEIN KINASE; THROMBIN; TYROSINE 3 MONOOXYGENASE;

EID: 74249104871     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2009.12.001     Document Type: Article
Times cited : (12)

References (92)
  • 2
    • 0018409525 scopus 로고
    • Corticosteroids in ischemic stroke
    • Anderson D.C., and Cranford R.E. Corticosteroids in ischemic stroke. Stroke 10 (1979) 68-71
    • (1979) Stroke , vol.10 , pp. 68-71
    • Anderson, D.C.1    Cranford, R.E.2
  • 3
    • 0029998009 scopus 로고    scopus 로고
    • Decreased antioxidant defence and increased oxidant stress during dexamethasone-induced apoptosis: bcl-2 prevents the loss of antioxidant enzyme activity
    • Baker A.F., Briehl M.M., Dorr R., and Powis P. Decreased antioxidant defence and increased oxidant stress during dexamethasone-induced apoptosis: bcl-2 prevents the loss of antioxidant enzyme activity. Cell Death Diff 3 (1996) 207-213
    • (1996) Cell Death Diff , vol.3 , pp. 207-213
    • Baker, A.F.1    Briehl, M.M.2    Dorr, R.3    Powis, P.4
  • 5
    • 0030071418 scopus 로고    scopus 로고
    • Synergy between chronic corticosterone and sodium azide treatments in producing a spatial learning deficit and inhibiting cytochrome oxidase activity
    • Bennett M.C., Milady G.W., Fleshner M., and Rose G.M. Synergy between chronic corticosterone and sodium azide treatments in producing a spatial learning deficit and inhibiting cytochrome oxidase activity. Proc Natl Acad Sci USA 93 (1996) 1330-1334
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1330-1334
    • Bennett, M.C.1    Milady, G.W.2    Fleshner, M.3    Rose, G.M.4
  • 6
    • 0037378758 scopus 로고    scopus 로고
    • Activation of pro-apoptotic cascade by dopamine in renal epithelial cells is fully dependent on hydrogen peroxide generation by monoamine oxidases
    • Bianchi P., Seguelas M.H., Parini A., and Cambon C. Activation of pro-apoptotic cascade by dopamine in renal epithelial cells is fully dependent on hydrogen peroxide generation by monoamine oxidases. J Am Soc Nephrol 14 (2003) 855-862
    • (2003) J Am Soc Nephrol , vol.14 , pp. 855-862
    • Bianchi, P.1    Seguelas, M.H.2    Parini, A.3    Cambon, C.4
  • 7
    • 0032888565 scopus 로고    scopus 로고
    • Dexamethasone increases eNOS gene expression and prevents renal vasoconstriction induced by cyclosporine
    • Bobadilla N.A., Tapia E., Jiménez F., Sánchez-Lozada L.G., Santamaría J., Monjardín A., et al. Dexamethasone increases eNOS gene expression and prevents renal vasoconstriction induced by cyclosporine. Am J Physiol 277 Renal Physiol. 46 (1999) F464-F471
    • (1999) Am J Physiol , vol.277 , Issue.Renal Physiol. 46
    • Bobadilla, N.A.1    Tapia, E.2    Jiménez, F.3    Sánchez-Lozada, L.G.4    Santamaría, J.5    Monjardín, A.6
  • 8
    • 0025344617 scopus 로고
    • A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the second national acute spinal cord injury study
    • Bracken M.B., Shepard M.J., Collins W.F., Holford T.R., Young W., Baskin D.S., et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the second national acute spinal cord injury study. N Engl J Med 322 (1990) 1405-1411
    • (1990) N Engl J Med , vol.322 , pp. 1405-1411
    • Bracken, M.B.1    Shepard, M.J.2    Collins, W.F.3    Holford, T.R.4    Young, W.5    Baskin, D.S.6
  • 9
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: a hard Akt to follow
    • Brazil D.P., and Hemmings B.A. Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem Sci 26 (2001) 657-664
    • (2001) Trends Biochem Sci , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 10
    • 34249828655 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: two approaches with therapeutic potential in the treatment of neurodegenerative disease
    • Burke R.E. Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: two approaches with therapeutic potential in the treatment of neurodegenerative disease. Pharmacol Ther 114 (2007) 261-277
    • (2007) Pharmacol Ther , vol.114 , pp. 261-277
    • Burke, R.E.1
  • 11
    • 0029925564 scopus 로고    scopus 로고
    • Monoamine oxidase B expression is selectively regulated by dexamethasone in cultured rat astrocytes
    • Carlo P., Violani E., Del Rio M., Olasmaa M., Santagati S., Maggi A., et al. Monoamine oxidase B expression is selectively regulated by dexamethasone in cultured rat astrocytes. Brain Res 711 (1996) 175-183
    • (1996) Brain Res , vol.711 , pp. 175-183
    • Carlo, P.1    Violani, E.2    Del Rio, M.3    Olasmaa, M.4    Santagati, S.5    Maggi, A.6
  • 12
    • 0037341150 scopus 로고    scopus 로고
    • Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia
    • Carreño-Müller E., Herrera A.J., de Pablos R.M., Tomás-Camardiel M., Venero J.L., Cano J., et al. Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia. J Neurochem 84 (2003) 1201-1214
    • (2003) J Neurochem , vol.84 , pp. 1201-1214
    • Carreño-Müller, E.1    Herrera, A.J.2    de Pablos, R.M.3    Tomás-Camardiel, M.4    Venero, J.L.5    Cano, J.6
  • 13
    • 0027535985 scopus 로고
    • Effects of a short period of vitamin E-deficient diet in the turnover of different neurotransmitters in substantia nigra and striatum of the rat
    • Castaño A., Herrera A.J., Cano J., and Machado A. Effects of a short period of vitamin E-deficient diet in the turnover of different neurotransmitters in substantia nigra and striatum of the rat. Neuroscience 53 (1993) 179-185
    • (1993) Neuroscience , vol.53 , pp. 179-185
    • Castaño, A.1    Herrera, A.J.2    Cano, J.3    Machado, A.4
  • 14
    • 0031881687 scopus 로고    scopus 로고
    • Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
    • Castaño A., Herrera A.J., Cano J., and Machado A. Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J Neurochem 70 (1998) 1584-1592
    • (1998) J Neurochem , vol.70 , pp. 1584-1592
    • Castaño, A.1    Herrera, A.J.2    Cano, J.3    Machado, A.4
  • 15
    • 0036077851 scopus 로고    scopus 로고
    • The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-alpha, IL-1beta and IFN-gamma
    • Castaño A., Herrera A.J., Cano J., and Machado A. The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-alpha, IL-1beta and IFN-gamma. J Neurochem 81 (2002) 150-157
    • (2002) J Neurochem , vol.81 , pp. 150-157
    • Castaño, A.1    Herrera, A.J.2    Cano, J.3    Machado, A.4
  • 16
    • 0032540194 scopus 로고    scopus 로고
    • Dexamethasone augments ischemia-induced extracellular accumulation of glutamate in gerbil hippocampus
    • Chen J., Adachi N., Tsubota S., Nagaro T., and Arai T. Dexamethasone augments ischemia-induced extracellular accumulation of glutamate in gerbil hippocampus. Eur J Pharmacol 347 (1998) 67-70
    • (1998) Eur J Pharmacol , vol.347 , pp. 67-70
    • Chen, J.1    Adachi, N.2    Tsubota, S.3    Nagaro, T.4    Arai, T.5
  • 17
    • 0038383698 scopus 로고    scopus 로고
    • Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo
    • Choi S.H., Joe E.H., Kim S.U., and Jin B.K. Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo. J Neurosci 23 (2003) 5877-5886
    • (2003) J Neurosci , vol.23 , pp. 5877-5886
    • Choi, S.H.1    Joe, E.H.2    Kim, S.U.3    Jin, B.K.4
  • 18
    • 0142250858 scopus 로고    scopus 로고
    • Thrombin induces nigral dopaminergic neurodegeneration in vivo by altering expression of death-related proteins
    • Choi S.H., Lee D.Y., Ryu J.K., Kim J., Joe E.H., and Jin B.K. Thrombin induces nigral dopaminergic neurodegeneration in vivo by altering expression of death-related proteins. Neurobiol Dis 14 (2003) 181-193
    • (2003) Neurobiol Dis , vol.14 , pp. 181-193
    • Choi, S.H.1    Lee, D.Y.2    Ryu, J.K.3    Kim, J.4    Joe, E.H.5    Jin, B.K.6
  • 19
    • 14244258303 scopus 로고    scopus 로고
    • Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3′-kinase signaling pathway
    • Chrysis D., Zaman F., Chagin A.S., Takigawa M., and Savendahl L. Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3′-kinase signaling pathway. Endocrinology 146 (2005) 1391-1397
    • (2005) Endocrinology , vol.146 , pp. 1391-1397
    • Chrysis, D.1    Zaman, F.2    Chagin, A.S.3    Takigawa, M.4    Savendahl, L.5
  • 20
    • 0031010596 scopus 로고    scopus 로고
    • Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow
    • Cohen G., Farooqui R., and Kesler N. Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow. Proc Natl Acad Sci USA 94 (1997) 4890-4894
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4890-4894
    • Cohen, G.1    Farooqui, R.2    Kesler, N.3
  • 21
    • 14644440756 scopus 로고    scopus 로고
    • Dopamine-dependent neurotoxicity of lipopolysaccharide in substantia nigra
    • de Pablos R.M., Herrera A.J., Villarán R.F., Cano J., and Machado A. Dopamine-dependent neurotoxicity of lipopolysaccharide in substantia nigra. FASEB J 19 (2005) 407-409
    • (2005) FASEB J , vol.19 , pp. 407-409
    • de Pablos, R.M.1    Herrera, A.J.2    Villarán, R.F.3    Cano, J.4    Machado, A.5
  • 22
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
    • Dickson D.W., Lee S.C., Mattiace L.A., Yen S.H., and Brosnan C. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7 (1993) 75-83
    • (1993) Glia , vol.7 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.H.4    Brosnan, C.5
  • 23
    • 0026783591 scopus 로고
    • Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils
    • Frackowiak J., Wisniewski H.M., Wegiel J., Merz G.S., Iqbal K., and Wang K.C. Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils. Acta Neuropathol 84 (1992) 225-233
    • (1992) Acta Neuropathol , vol.84 , pp. 225-233
    • Frackowiak, J.1    Wisniewski, H.M.2    Wegiel, J.3    Merz, G.S.4    Iqbal, K.5    Wang, K.C.6
  • 24
    • 0022475328 scopus 로고
    • Lowry protein assay using an automatic microtiter plate spectrophotometer
    • Fryer H.J., Davis G.E., Manthorpe M., and Varon S. Lowry protein assay using an automatic microtiter plate spectrophotometer. Anal Biochem 153 (1986) 262-266
    • (1986) Anal Biochem , vol.153 , pp. 262-266
    • Fryer, H.J.1    Davis, G.E.2    Manthorpe, M.3    Varon, S.4
  • 25
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation
    • Gavrieli Y., Sherman Y., and Ben-Sasson S.A. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J Cell Biol 119 (1992) 493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 26
    • 0035959931 scopus 로고    scopus 로고
    • Parkin and the molecular pathways of Parkinson's disease
    • Giasson B.I., and Lee V.M. Parkin and the molecular pathways of Parkinson's disease. Neuron 31 (2001) 885-888
    • (2001) Neuron , vol.31 , pp. 885-888
    • Giasson, B.I.1    Lee, V.M.2
  • 27
    • 0034284153 scopus 로고    scopus 로고
    • Serine proteases and brain damage-is there a link?
    • Gingrich M.B., and Traynelis S.F. Serine proteases and brain damage-is there a link?. Trends Neurosci 23 (2000) 399-407
    • (2000) Trends Neurosci , vol.23 , pp. 399-407
    • Gingrich, M.B.1    Traynelis, S.F.2
  • 28
    • 0022897760 scopus 로고
    • A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins
    • Gloor S., Odink K., Guenther J., Nick H., and Monard D. A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins. Cell 47 (1986) 687-693
    • (1986) Cell , vol.47 , pp. 687-693
    • Gloor, S.1    Odink, K.2    Guenther, J.3    Nick, H.4    Monard, D.5
  • 29
    • 0022110035 scopus 로고
    • A glia-derived neurite promoting factor with protease inhibitory activity
    • Guenther J., Nick H., and Monard D. A glia-derived neurite promoting factor with protease inhibitory activity. EMBO J 4 (1985) 1963-1966
    • (1985) EMBO J , vol.4 , pp. 1963-1966
    • Guenther, J.1    Nick, H.2    Monard, D.3
  • 30
    • 0034807776 scopus 로고    scopus 로고
    • Estrogen (E2) and glucocorticoid (Gc) effects on microglia and A beta clearance in vitro and in vivo
    • Harris-White M.E., Chu T., Miller S.A., Simmons M., Teter B., Nash D., et al. Estrogen (E2) and glucocorticoid (Gc) effects on microglia and A beta clearance in vitro and in vivo. Neurochem Int 39 (2001) 435-448
    • (2001) Neurochem Int , vol.39 , pp. 435-448
    • Harris-White, M.E.1    Chu, T.2    Miller, S.A.3    Simmons, M.4    Teter, B.5    Nash, D.6
  • 31
    • 0033835748 scopus 로고    scopus 로고
    • The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system
    • Herrera A.J., Castaño A., Venero J.L., Cano J., and Machado A. The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system. Neurobiol Dis 7 (2000) 429-447
    • (2000) Neurobiol Dis , vol.7 , pp. 429-447
    • Herrera, A.J.1    Castaño, A.2    Venero, J.L.3    Cano, J.4    Machado, A.5
  • 32
    • 42449162417 scopus 로고    scopus 로고
    • The intrastriatal injection of thrombin in rat induced a retrograde apoptotic degeneration of nigral dopaminergic neurons through synaptic elimination
    • Herrera A.J., de Pablos R.M., Carreño-Müller E., Villarán R.F., Venero J.L., Tomás-Camardiel M., et al. The intrastriatal injection of thrombin in rat induced a retrograde apoptotic degeneration of nigral dopaminergic neurons through synaptic elimination. J Neurochem 105 (2008) 750-762
    • (2008) J Neurochem , vol.105 , pp. 750-762
    • Herrera, A.J.1    de Pablos, R.M.2    Carreño-Müller, E.3    Villarán, R.F.4    Venero, J.L.5    Tomás-Camardiel, M.6
  • 33
    • 0034052904 scopus 로고    scopus 로고
    • Glial cells and Parkinson's disease
    • Hirsch E.C. Glial cells and Parkinson's disease. J Neurol 247 (2000) II58-II62
    • (2000) J Neurol , vol.247
    • Hirsch, E.C.1
  • 34
    • 44349194287 scopus 로고    scopus 로고
    • Thrombin-induced microglial activation contributes to the degeneration of nigral dopaminergic neurons in vivo
    • Huang C.F., Li G., Ma R., Sun S.G., and Chen J.G. Thrombin-induced microglial activation contributes to the degeneration of nigral dopaminergic neurons in vivo. Neurosci Bull 24 (2008) 66-72
    • (2008) Neurosci Bull , vol.24 , pp. 66-72
    • Huang, C.F.1    Li, G.2    Ma, R.3    Sun, S.G.4    Chen, J.G.5
  • 35
    • 0033121299 scopus 로고    scopus 로고
    • FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells
    • Hunot S., Dugas N., Faucheux B., Hartmann A., Tardieu M., Debre P., et al. FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells. J Neurosci 19 (1999) 3440-3447
    • (1999) J Neurosci , vol.19 , pp. 3440-3447
    • Hunot, S.1    Dugas, N.2    Faucheux, B.3    Hartmann, A.4    Tardieu, M.5    Debre, P.6
  • 37
    • 0037428173 scopus 로고    scopus 로고
    • Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction
    • Iuchi T., Akaike M., Mitsui T., Ohshima Y., Shintani Y., Azuma H., et al. Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction. Circ Res 92 (2003) 81-87
    • (2003) Circ Res , vol.92 , pp. 81-87
    • Iuchi, T.1    Akaike, M.2    Mitsui, T.3    Ohshima, Y.4    Shintani, Y.5    Azuma, H.6
  • 38
    • 0037035562 scopus 로고    scopus 로고
    • Thrombin induces IL-10 production in microglia as a negative feedback regulator of TNF-[alpha] release
    • Kim K.Y., Kim M.Y., Choi H.S., Jin B.K., Kim S.U., and Lee Y.B. Thrombin induces IL-10 production in microglia as a negative feedback regulator of TNF-[alpha] release. Neuroreport 13 (2002) 849-852
    • (2002) Neuroreport , vol.13 , pp. 849-852
    • Kim, K.Y.1    Kim, M.Y.2    Choi, H.S.3    Jin, B.K.4    Kim, S.U.5    Lee, Y.B.6
  • 39
    • 0034663061 scopus 로고    scopus 로고
    • Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia
    • Kim W.G., Mohney R.P., Wilson B., Jeohn G.H., Liu B., and Hong J.S. Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20 (2000) 6309-6316
    • (2000) J Neurosci , vol.20 , pp. 6309-6316
    • Kim, W.G.1    Mohney, R.P.2    Wilson, B.3    Jeohn, G.H.4    Liu, B.5    Hong, J.S.6
  • 41
    • 0036633664 scopus 로고    scopus 로고
    • Regulation of JNK/ERK activation, cell apoptosis, and tissue regeneration by monoamine oxidases after renal ischemia-reperfusion
    • Kunduzova O.R., Bianchi P., Pizzinat N., Escourrou G., Seguelas M.H., Parini A., et al. Regulation of JNK/ERK activation, cell apoptosis, and tissue regeneration by monoamine oxidases after renal ischemia-reperfusion. FASEB J 16 (2002) 1129-1131
    • (2002) FASEB J , vol.16 , pp. 1129-1131
    • Kunduzova, O.R.1    Bianchi, P.2    Pizzinat, N.3    Escourrou, G.4    Seguelas, M.H.5    Parini, A.6
  • 42
    • 0035503074 scopus 로고    scopus 로고
    • Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease
    • Le W., Rowe D., Xie W., Ortiz I., He Y., and Appel S.H. Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease. J Neurosci 21 (2001) 8447-8455
    • (2001) J Neurosci , vol.21 , pp. 8447-8455
    • Le, W.1    Rowe, D.2    Xie, W.3    Ortiz, I.4    He, Y.5    Appel, S.H.6
  • 43
    • 0842312950 scopus 로고    scopus 로고
    • Glucocorticoid receptor counteracts tumorigenic activity of akt in skin through interference with the phosphatidylinositol 3-kinase signaling pathway
    • Leis H., Page A., Ramirez A., Bravo A., Segrelles C., Paramio J., et al. Glucocorticoid receptor counteracts tumorigenic activity of akt in skin through interference with the phosphatidylinositol 3-kinase signaling pathway. Mol Endocrinol 18 (2004) 303-311
    • (2004) Mol Endocrinol , vol.18 , pp. 303-311
    • Leis, H.1    Page, A.2    Ramirez, A.3    Bravo, A.4    Segrelles, C.5    Paramio, J.6
  • 46
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • Manning B.D., and Cantley L.C. AKT/PKB signaling: navigating downstream. Cell 129 (2007) 1261-1274
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 47
    • 23444436335 scopus 로고    scopus 로고
    • Monoamine oxidase-A is a major target gene for glucocorticoids in human skeletal muscle cells
    • Manoli I., Le H., Alesci S., McFann K.K., Su Y.A., Kino T., et al. Monoamine oxidase-A is a major target gene for glucocorticoids in human skeletal muscle cells. FASEB J 19 (2005) 1359-1361
    • (2005) FASEB J , vol.19 , pp. 1359-1361
    • Manoli, I.1    Le, H.2    Alesci, S.3    McFann, K.K.4    Su, Y.A.5    Kino, T.6
  • 49
    • 28444435458 scopus 로고    scopus 로고
    • Inflammation, the complement system and the diseases of aging
    • McGeer E.G., Klegeris A., and McGeer P.L. Inflammation, the complement system and the diseases of aging. Neurobiol Aging 26 (2005) 94-97
    • (2005) Neurobiol Aging , vol.26 , pp. 94-97
    • McGeer, E.G.1    Klegeris, A.2    McGeer, P.L.3
  • 50
    • 0027391471 scopus 로고
    • In vitro studies on the effects of dehydroepiandrosterone and corticosterone on hepatic steroid receptor binding and mitochondrial respiration
    • McIntosh M.K., Pan J.-S., and Berdanier C.D. In vitro studies on the effects of dehydroepiandrosterone and corticosterone on hepatic steroid receptor binding and mitochondrial respiration. Comp Biochem Physiol 104A (1993) 147-153
    • (1993) Comp Biochem Physiol , vol.104 A , pp. 147-153
    • McIntosh, M.K.1    Pan, J.-S.2    Berdanier, C.D.3
  • 51
    • 0027492461 scopus 로고
    • Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor
    • McNamara C.A., Sarembock I.J., Gimple L.W., Fenton II J.W., Coughlin S.R., and Owens G.K. Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor. J Clin Invest 91 (1993) 94-98
    • (1993) J Clin Invest , vol.91 , pp. 94-98
    • McNamara, C.A.1    Sarembock, I.J.2    Gimple, L.W.3    Fenton II, J.W.4    Coughlin, S.R.5    Owens, G.K.6
  • 52
    • 0035890083 scopus 로고    scopus 로고
    • Progressive neuronal and motor dysfunction in mice overexpressing the serine protease inhibitor protease nexin-1 in postmitotic neurons
    • Meins M., Piosik P., Schaeren-Wiemers N., Franzoni S., Troncoso E., Kiss J.Z., et al. Progressive neuronal and motor dysfunction in mice overexpressing the serine protease inhibitor protease nexin-1 in postmitotic neurons. J Neurosci 21 (2001) 8830-8841
    • (2001) J Neurosci , vol.21 , pp. 8830-8841
    • Meins, M.1    Piosik, P.2    Schaeren-Wiemers, N.3    Franzoni, S.4    Troncoso, E.5    Kiss, J.Z.6
  • 53
    • 0032996598 scopus 로고    scopus 로고
    • Down-regulation of microglial cyclo-oxygenase-2 and inducible nitric oxide synthase expression by lipocortin 1
    • Minghetti L., Nicolini A., Polazzi E., Greco A., Perretti M., Parente L., et al. Down-regulation of microglial cyclo-oxygenase-2 and inducible nitric oxide synthase expression by lipocortin 1. Br J Pharmacol 126 (1999) 1307-1314
    • (1999) Br J Pharmacol , vol.126 , pp. 1307-1314
    • Minghetti, L.1    Nicolini, A.2    Polazzi, E.3    Greco, A.4    Perretti, M.5    Parente, L.6
  • 54
    • 0036039813 scopus 로고    scopus 로고
    • Chronic corticosteroid administration causes mitochondrial dysfunction in skeletal muscle
    • Mitsui T., Azuma H., Nagasawa M., Iuchi T., Akaike M., Odomi M., et al. Chronic corticosteroid administration causes mitochondrial dysfunction in skeletal muscle. J Neurol 249 (2002) 1004-1009
    • (2002) J Neurol , vol.249 , pp. 1004-1009
    • Mitsui, T.1    Azuma, H.2    Nagasawa, M.3    Iuchi, T.4    Akaike, M.5    Odomi, M.6
  • 55
    • 0037418868 scopus 로고    scopus 로고
    • Facilitation of ischemia-induced release of dopamine and neuronal damage by dexamethasone in the rat striatum
    • Mitsuyo T., Adachi N., Yorozuya T., Tabo E., Nagaro T., and Arai T. Facilitation of ischemia-induced release of dopamine and neuronal damage by dexamethasone in the rat striatum. Eur J Pharmacol 465 (2003) 267-274
    • (2003) Eur J Pharmacol , vol.465 , pp. 267-274
    • Mitsuyo, T.1    Adachi, N.2    Yorozuya, T.3    Tabo, E.4    Nagaro, T.5    Arai, T.6
  • 56
    • 0033822556 scopus 로고    scopus 로고
    • Thrombin-induced activation of cultured rodent microglia
    • Möller T., Hanisch U.K., and Ransom B.R. Thrombin-induced activation of cultured rodent microglia. J Neurochem 75 (2000) 1539-1547
    • (2000) J Neurochem , vol.75 , pp. 1539-1547
    • Möller, T.1    Hanisch, U.K.2    Ransom, B.R.3
  • 57
    • 33646488804 scopus 로고    scopus 로고
    • Activation of microglial cells by thrombin: past, present, and future
    • Möller T., Weinstein J.R., and Hanisch U.K. Activation of microglial cells by thrombin: past, present, and future. Semin Thromb Hemost 32 (2006) 69-76
    • (2006) Semin Thromb Hemost , vol.32 , pp. 69-76
    • Möller, T.1    Weinstein, J.R.2    Hanisch, U.K.3
  • 58
    • 0022645283 scopus 로고
    • High dose steroid treatment in cerebral infarction
    • Norris J.W., and Hachinski V.C. High dose steroid treatment in cerebral infarction. Br Med J (Clin Res Ed) 292 (1986) 21-23
    • (1986) Br Med J (Clin Res Ed) , vol.292 , pp. 21-23
    • Norris, J.W.1    Hachinski, V.C.2
  • 59
    • 0036588397 scopus 로고    scopus 로고
    • Dexamethasone-mediated regulation of death and differentiation of muscle cells. Is hydrogen peroxide involved in the process?
    • Orzechowski A., Grizard J., Jank M., Gajkowska B., Lokociejewska M., Zaron-Teperek M., et al. Dexamethasone-mediated regulation of death and differentiation of muscle cells. Is hydrogen peroxide involved in the process?. Reprod Nutr Dev 42 (2002) 197-216
    • (2002) Reprod Nutr Dev , vol.42 , pp. 197-216
    • Orzechowski, A.1    Grizard, J.2    Jank, M.3    Gajkowska, B.4    Lokociejewska, M.5    Zaron-Teperek, M.6
  • 60
    • 0041928098 scopus 로고    scopus 로고
    • Delineation of signalling pathway leading to antioxidant-dependent inhibition of dexamethasone-mediated muscle cell death
    • Orzechowski A., Jank M., Gajkowska B., Sadkowski T., Godlewski M.M., and Ostaszewski P. Delineation of signalling pathway leading to antioxidant-dependent inhibition of dexamethasone-mediated muscle cell death. J Muscle Res Cell Motil 24 (2003) 33-53
    • (2003) J Muscle Res Cell Motil , vol.24 , pp. 33-53
    • Orzechowski, A.1    Jank, M.2    Gajkowska, B.3    Sadkowski, T.4    Godlewski, M.M.5    Ostaszewski, P.6
  • 61
    • 3042771402 scopus 로고    scopus 로고
    • Oxidative stress-associated mitochondrial dysfunction in corticosteroid-treated muscle cells
    • Oshima Y., Kuroda Y., Kunishige M., Matsumoto T., and Mitsui T. Oxidative stress-associated mitochondrial dysfunction in corticosteroid-treated muscle cells. Muscle Nerve 30 (2004) 49-54
    • (2004) Muscle Nerve , vol.30 , pp. 49-54
    • Oshima, Y.1    Kuroda, Y.2    Kunishige, M.3    Matsumoto, T.4    Mitsui, T.5
  • 64
    • 0027976526 scopus 로고
    • Glia-derived nexin/protease nexin-1 is expressed by a subset of neurons in the rat brain
    • Reinhard E., Suidan H.S., Pavlik A., and Monard D. Glia-derived nexin/protease nexin-1 is expressed by a subset of neurons in the rat brain. J Neurosci Res 37 (1994) 256-270
    • (1994) J Neurosci Res , vol.37 , pp. 256-270
    • Reinhard, E.1    Suidan, H.S.2    Pavlik, A.3    Monard, D.4
  • 66
    • 0032487830 scopus 로고    scopus 로고
    • Synthesis and biological effects of NO in malignant glioma cells: modulation by cytokines including CD95L and TGF-beta, dexamethasone, and p53 gene transfer
    • Rieger J., Stander M., Loschmann P.A., Heneka M., Dichgans J., Klockgether T., et al. Synthesis and biological effects of NO in malignant glioma cells: modulation by cytokines including CD95L and TGF-beta, dexamethasone, and p53 gene transfer. Oncogene 17 (1998) 2323-2332
    • (1998) Oncogene , vol.17 , pp. 2323-2332
    • Rieger, J.1    Stander, M.2    Loschmann, P.A.3    Heneka, M.4    Dichgans, J.5    Klockgether, T.6
  • 69
    • 0034730753 scopus 로고    scopus 로고
    • Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B
    • Ryu J., Pyo H., Jou I., and Joe E. Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B. J Biol Chem 275 (2000) 29955-29959
    • (2000) J Biol Chem , vol.275 , pp. 29955-29959
    • Ryu, J.1    Pyo, H.2    Jou, I.3    Joe, E.4
  • 70
    • 0017839933 scopus 로고
    • Is there a real treatment for stroke? Clinical and statistical comparison of different treatments in 300 patients
    • Santambrogio S., Martinotti R., Sardella F., Porro F., and Randazzo A. Is there a real treatment for stroke? Clinical and statistical comparison of different treatments in 300 patients. Stroke 9 (1978) 130-132
    • (1978) Stroke , vol.9 , pp. 130-132
    • Santambrogio, S.1    Martinotti, R.2    Sardella, F.3    Porro, F.4    Randazzo, A.5
  • 71
    • 0346121830 scopus 로고    scopus 로고
    • Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity
    • Seymour C.B., Mothersill C., Mooney R., Moriarty M., and Tipton K.F. Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity. Br J Cancer 89 (2003) 1979-1986
    • (2003) Br J Cancer , vol.89 , pp. 1979-1986
    • Seymour, C.B.1    Mothersill, C.2    Mooney, R.3    Moriarty, M.4    Tipton, K.F.5
  • 72
    • 0037386618 scopus 로고    scopus 로고
    • Molecular mechanisms underlying dexamethasone inhibition of inos expression and activity in c6 glioma cells
    • Shinoda J., Mclaughlin K.E., Swaroop G.R., Yamaguchi S.-I., Holmes M.C., and Whittle I.E. Molecular mechanisms underlying dexamethasone inhibition of inos expression and activity in c6 glioma cells. Glia 42 (2003) 68-76
    • (2003) Glia , vol.42 , pp. 68-76
    • Shinoda, J.1    Mclaughlin, K.E.2    Swaroop, G.R.3    Yamaguchi, S.-I.4    Holmes, M.C.5    Whittle, I.E.6
  • 73
    • 0027236605 scopus 로고
    • Cytokine regulate l-arginine-dependent cyclic GMP production in rat glial cells
    • Simmons M.L., and Murphy S. Cytokine regulate l-arginine-dependent cyclic GMP production in rat glial cells. Eur J Neurosci 5 (1993) 825-831
    • (1993) Eur J Neurosci , vol.5 , pp. 825-831
    • Simmons, M.L.1    Murphy, S.2
  • 74
    • 0034464217 scopus 로고    scopus 로고
    • Dexamethasone inhibits insulin-like growth factor signaling and potentiates myoblast apoptosis
    • Singleton J.R., Baker B.L., and Thorburn A. Dexamethasone inhibits insulin-like growth factor signaling and potentiates myoblast apoptosis. Endocrinology 141 (2000) 2945-2950
    • (2000) Endocrinology , vol.141 , pp. 2945-2950
    • Singleton, J.R.1    Baker, B.L.2    Thorburn, A.3
  • 75
    • 0029089908 scopus 로고
    • Protease nexin-1 and thrombin modulate neuronal Ca2+ homeostasis and sensitivity to glucose deprivation-induced injury
    • Smith-Swintosky V.L., Zimmer S., Fenton J.W., and Mattson II M.P. Protease nexin-1 and thrombin modulate neuronal Ca2+ homeostasis and sensitivity to glucose deprivation-induced injury. J Neurosci 15 (1995) 5840-5850
    • (1995) J Neurosci , vol.15 , pp. 5840-5850
    • Smith-Swintosky, V.L.1    Zimmer, S.2    Fenton, J.W.3    Mattson II, M.P.4
  • 76
    • 0036326804 scopus 로고    scopus 로고
    • Participation of protease-activated receptor-1 in thrombin-induced microglial activation
    • Suo Z., Wu M., Ameenuddin S., Anderson H.E., Zoloty J.E., Citron B.A., et al. Participation of protease-activated receptor-1 in thrombin-induced microglial activation. J Neurochem 80 (2002) 655-666
    • (2002) J Neurochem , vol.80 , pp. 655-666
    • Suo, Z.1    Wu, M.2    Ameenuddin, S.3    Anderson, H.E.4    Zoloty, J.E.5    Citron, B.A.6
  • 77
    • 0042904881 scopus 로고    scopus 로고
    • Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation
    • Suo Z., Wu M., Citron B.A., Gao C., and Festoff B.W. Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation. J Biol Chem 278 (2003) 37681-37689
    • (2003) J Biol Chem , vol.278 , pp. 37681-37689
    • Suo, Z.1    Wu, M.2    Citron, B.A.3    Gao, C.4    Festoff, B.W.5
  • 78
    • 0031149325 scopus 로고    scopus 로고
    • Glucocorticoid- and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids
    • Tanaka J., Fujita H., Matsuda S., Toku K., Sakanaka M., and Maeda N. Glucocorticoid- and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids. Glia 20 (1997) 23-37
    • (1997) Glia , vol.20 , pp. 23-37
    • Tanaka, J.1    Fujita, H.2    Matsuda, S.3    Toku, K.4    Sakanaka, M.5    Maeda, N.6
  • 79
    • 0032519934 scopus 로고    scopus 로고
    • Lipopolysaccharide regulates both serotonin- and thrombin-induced intracellular calcium mobilization in rat C6 glioma cells: possible involvement of nitric oxide synthase-mediated pathway
    • Tawara Y., Kagaya A., Uchitomi Y., Horiguchi J., and Yamawaki S. Lipopolysaccharide regulates both serotonin- and thrombin-induced intracellular calcium mobilization in rat C6 glioma cells: possible involvement of nitric oxide synthase-mediated pathway. J Neurosci Res 51 (1998) 517-525
    • (1998) J Neurosci Res , vol.51 , pp. 517-525
    • Tawara, Y.1    Kagaya, A.2    Uchitomi, Y.3    Horiguchi, J.4    Yamawaki, S.5
  • 80
    • 70449518417 scopus 로고    scopus 로고
    • Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis
    • Tazik S., Johnson S., Lu D., Johnson C., Youdim M.B., Stockmeier C.A., et al. Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis. Neurotox Res 15 (2009) 284-290
    • (2009) Neurotox Res , vol.15 , pp. 284-290
    • Tazik, S.1    Johnson, S.2    Lu, D.3    Johnson, C.4    Youdim, M.B.5    Stockmeier, C.A.6
  • 81
    • 0015795734 scopus 로고
    • Dexamethasone as treatment in acute cerebrovascular disease. 1. A controlled study in intracerebral haemorrhage
    • Tellez H., and Bauer R.B. Dexamethasone as treatment in acute cerebrovascular disease. 1. A controlled study in intracerebral haemorrhage. Stroke 4 (1973) 541-546
    • (1973) Stroke , vol.4 , pp. 541-546
    • Tellez, H.1    Bauer, R.B.2
  • 82
    • 2342538502 scopus 로고    scopus 로고
    • Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxinitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system
    • Tomás-Camardiel M., Rite I., Herrera Aj, de Pablos R.M., Cano J., Machado A., and Venero J.L. Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxinitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system. Neurobiol Dis 16 (2004) 190-201
    • (2004) Neurobiol Dis , vol.16 , pp. 190-201
    • Tomás-Camardiel, M.1    Rite, I.2    Herrera Aj3    de Pablos, R.M.4    Cano, J.5    Machado, A.6    Venero, J.L.7
  • 83
    • 0032100686 scopus 로고    scopus 로고
    • Co-existence of two types of [Ca2+]I-inducing protease-activated receptors (PAR-1 and PAR-2) in rat astrocytes and C6 glioma cells
    • Ubl J.J., Vöhringer C., and Reiser G. Co-existence of two types of [Ca2+]I-inducing protease-activated receptors (PAR-1 and PAR-2) in rat astrocytes and C6 glioma cells. Neuroscience 86 (1998) 597-609
    • (1998) Neuroscience , vol.86 , pp. 597-609
    • Ubl, J.J.1    Vöhringer, C.2    Reiser, G.3
  • 84
    • 0029012029 scopus 로고
    • Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults
    • Vaughan P.J., Pike C.J., Cotman C.W., and Cunningham D.D. Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J Neurosci 15 (1995) 5389-5401
    • (1995) J Neurosci , vol.15 , pp. 5389-5401
    • Vaughan, P.J.1    Pike, C.J.2    Cotman, C.W.3    Cunningham, D.D.4
  • 85
    • 0015596693 scopus 로고
    • Oxidative respiration of skeletal muscle in experimental corticosteroid myopathy
    • Vignos P.J., and Greene R. Oxidative respiration of skeletal muscle in experimental corticosteroid myopathy. J Lab Clin Med 81 (1973) 365-378
    • (1973) J Lab Clin Med , vol.81 , pp. 365-378
    • Vignos, P.J.1    Greene, R.2
  • 87
    • 0030960334 scopus 로고    scopus 로고
    • Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264.7 cells by dexamethasone: evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation
    • Walker G., Pfeilschifter J., and Kunz D. Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264.7 cells by dexamethasone: evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation. J Biol Chem 272 (1997) 16679-16687
    • (1997) J Biol Chem , vol.272 , pp. 16679-16687
    • Walker, G.1    Pfeilschifter, J.2    Kunz, D.3
  • 88
    • 0036006726 scopus 로고    scopus 로고
    • Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signalling
    • Wang H., Ubl J.J., and Reiser G. Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signalling. Glia 37 (2002) 53-63
    • (2002) Glia , vol.37 , pp. 53-63
    • Wang, H.1    Ubl, J.J.2    Reiser, G.3
  • 89
    • 0036838021 scopus 로고    scopus 로고
    • Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways
    • Wang H., Ubl J.J., Stricker R., and Reiser G. Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways. Am J Physiol: Cell Physiol 283 (2002) C1351-C1364
    • (2002) Am J Physiol: Cell Physiol , vol.283
    • Wang, H.1    Ubl, J.J.2    Stricker, R.3    Reiser, G.4
  • 90
    • 0028914068 scopus 로고
    • Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA
    • Weinstein J.R., Gold S.J., Cunningham D.D., and Gall C.M. Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J Neurosci 15 (1995) 2906-2919
    • (1995) J Neurosci , vol.15 , pp. 2906-2919
    • Weinstein, J.R.1    Gold, S.J.2    Cunningham, D.D.3    Gall, C.M.4
  • 91
    • 0031883069 scopus 로고    scopus 로고
    • Glucocorticoid inhibition of adjuvant arthritis synovial macrophage nitric oxide production: role of lipocortin 1
    • Yang Y.H., Hutchinson P., Santos L.L., and Morand E.F. Glucocorticoid inhibition of adjuvant arthritis synovial macrophage nitric oxide production: role of lipocortin 1. Clin Exp Immunol 111 (1998) 117-122
    • (1998) Clin Exp Immunol , vol.111 , pp. 117-122
    • Yang, Y.H.1    Hutchinson, P.2    Santos, L.L.3    Morand, E.F.4
  • 92
    • 0024556215 scopus 로고
    • Steroid regulation of monoamine oxidase activity in the adrenal medulla
    • Youdim M.B., Banerjee D.K., Kelner K., Offutt L., and Pollard H.B. Steroid regulation of monoamine oxidase activity in the adrenal medulla. FASEB J 3 (1989) 1753-1759
    • (1989) FASEB J , vol.3 , pp. 1753-1759
    • Youdim, M.B.1    Banerjee, D.K.2    Kelner, K.3    Offutt, L.4    Pollard, H.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.