Immunomodulatory effects of Lagenaria siceraria fruits in rats

Pharmacognosy Magazine

Volumn 4, Issue 16 SUPPL., 2008, Pages

  Gangwal, A ^a   Parmar, S K ^a   Gupta, G L ^b   Rana, A C ^b   Sheth, N R ^a  

^a SAURASHTRA UNIVERSITY   (India)

^b BN College of Pharmacy   (India)

Author keywords

Cucurbitaceae; Delayed type hypersensitivity; Humoral antibody titre; Immunomodulation; Lagenaria siceraria

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTIBODY; BUTANOL; LAGENARIA SICERARIA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DRUG DOSE INCREASE; DRUG ISOLATION; FEMALE; FRUIT; IMMUNOMODULATION; LEUKOCYTE; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MALE; NONHUMAN; RAT;

EID: 74249097764     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. R. Solecki and I.V. Shanidar. A Neanderthal flower burial in northern Iraq. Science 190: 880-1 (1975).
2. C.K. Atal, M.L. Sharma, A. Kaul and A. Khajuria. Immunomodulating agents of plant origin. I: Preliminary screening. J. Ethnopharmacol. 18: 133-41 (1986).
3. A.A. Mungantiwar, A.M. Nair, U.A. Shinde, V.J. Dikshit, M.N. Saraf, V.S. Thakur and K.B. Sainis. Studies on immunomodulatory effects of Boerhaavia diffusa alkaloidal fraction. J. Ethnopharmacol. 65: 125-31 (1999).
4. N.S. Balekar and D.K. Jain. Screening methods for immunomodulatory agents -A review. Indian Drugs 43(7): 525-34 (2006).
5. B. Krauze and W. Cisowski. Isolation and identification of C-glycosides flavone from Lagenaria siceraria L. Acta Poloniae Pharmaceutica 52(2): 137-9 (1995).
6. K.R. Kirtikar. Indian medicinal plants, (Oriental Enterprises, Dehradun, 2001) pp. 722-3.
7. Anonymous. Wealth of India: A dictionary of Indian raw material products, (Council of Industrial and Scientific Research, New Delhi, 1962) pp. 116.
8. K.R. Khandelwal. Preliminary phytochemical screening. In: Practical Pharmacognosy. 6th edition, (Nirali Prakashan, Pune, 2006) pp.149-53.
9. A.R. Bafna and S.H. Mishra. Immunomodulatory activity of methanol extract of roots of Cissampelos pareira Linn. Ars. Pharm. 46(3): 253-62 (2005).
10. N.S. Doherty. Selective effects of immunosuppressive agents against the delayed hypersensitivity response and humoral response to sheep red blood cells in mice. Agents Actions 11(3): 237-42 (1981).
11. U.A. Shinde, A.S. Phadke, A.M. Nair, A.A. Mungantiwar, V.J. Dikshit and M.N. Saraf. Preliminary studies on the immunomodulatory activity of Cedrus deodara wood oil. Fitoterapia 70: 333-9 (1999).
12. T.J. Raphael and G. Kuttan. Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system. Phytomedicine 10: 483-9 (2003).
13. B.V. Ghule, G. Murugananthan, P.D. Nakhat and P.G. Yeole. Immunostimulant effects of Capparis zeylanica Linn. leaves. J. Ethnopharmacol. 108: 311-5 (2006).
14. B. Benacerraf. A hypothesis to relate the specificity of T lymphocyte and the activity of I region specific Ir genes in macrophages and B lymphocytes. J. Immunol. 20: 1809-12 (1978).
15. D.E. Griswold, S. Alessi and D.T. Walz. Stimulation of contact sensitivity to oxazolone by disodium cromoglycate. Int. Ach. Allergy Appl. Immunol. 69: 93-7 (1982).
16. B.V. Ghule, M.H. Ghante, A.B. Upaganlwar and P.G. Yeole. Analgesic and anti-inflammatory activities of Lagenaria siceraria Stand. fruit juice extract in rats and mice. Phcog. Mag. 2(8): 232-8 (2006).
17. B.V. Ghule, M.H. Ghante, P.G. Yeole and A.N. Saoji. Diuretic activity of Lagenaria siceraria fruit extracts in rats. Ind. J. Pharm. Sci. 69(6): 817-9 (2007).