Stable expression of a foreign protein by a replication-competent rubella viral vector

Vaccine

Volumn 28, Issue 5, 2010, Pages 1181-1187

  Spadaccini, Angelo ^a   Virnik, Konstantin ^a   Ni, Yisheng ^a   Prutzman, Kirk ^a   Berkower, Ira ^a  

^a Office of Vaccine Research and Review   (United States)

Author keywords

Live; Replicating; Rubella; Vector; Viral

Indexed keywords

GREEN FLUORESCENT PROTEIN; LIVE VACCINE; NONSTRUCTURAL PROTEIN P150; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS PROTEIN; VIRUS VECTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE INSERTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RUBELLA VIRUS; VIROGENESIS; VIRUS ATTENUATION; VIRUS REPLICATION;

ANIMALS; CERCOPITHECUS AETHIOPS; GENE EXPRESSION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; RECOMBINANT PROTEINS; RUBELLA VIRUS; TRANSDUCTION, GENETIC; VERO CELLS; VIRAL VACCINES; VIRUS REPLICATION;

EID: 74249096990     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.11.037     Document Type: Article

References (30)

1. Parkman P.D., Phillips P.E., Kirschstein R.L., and Meyer H.M. Experimental rubella virus infection in the rhesus monkey. J Immunol 95 (1965) 743-752
2. Meyer H.M., Parkman P.D., and Panos T.C. Attenuated rubella virus: II. Production of an experimental live-virus vaccine and clinical trial. N Engl J Med 275 11 (1966) 575-580
3. Plotkin S.A., and Reef S. Rubella vaccine. In: Plotkin S.A., and Orenstein W.A. (Eds). Vaccines. 4th ed. (2004), Saunders, Philadelphia 707-743
4. Pugachev K.V., Abernathy E.S., and Frey T.K. Improvement of the specific infectivity of the rubella virus (RUB) infectious clone: determinants of cytopathogenicity induced by RUB map to the nonstructural proteins. J Virol 71 (1999) 562-568
5. Pugachev K.V., Galinski M.S., and Frey T.K. Infectious cDNA clone of the RA27/3 vaccine strain of Rubella virus. Virology 273 (2000) 189-197
6. Frey T.K. Molecular biology of rubella virus. Adv Virus Res 44 (1994) 69-160
7. Pugachev K.V., Tzeng W.-P., and Frey T.K. Development of a rubella virus vaccine expression vector: use of a picornavirus internal ribosome entry site increases stability of expression. J Virol 74 (2000) 10811-10815
8. Tzeng W.-P., Chen M.-H., Derdeyn C.A., and Frey T.K. Rubella virus DI RNAs and replicons: requirement for nonstructural proteins acting in cis for amplification by helper virus. Virology 289 (2001) 63-73
9. Tzeng W.-P., and Frey T.K. Complementation of a deletion in the rubella virus P150 nonstructural protein by the viral capsid protein. J Virol 77 (2003) 9502-9510
10. Kujala P., Ahola T., Ehsani N., Auvinen P., Vihinen H., and Kääriäinen L. Intracellular distribution of rubella virus nonstructural protein P150. J Virol 73 (1999) 7805-7811
11. Lee J.Y., Marshall J.A., and Bowden D.S. Replication complexes associated with the morphogenesis of rubella virus. Arch Virol 122 (1992) 95-106
12. Froshauer S., Kartenbeck J., and Helenius A. Alphavirus RNA replicase is located on the cytoplasmic surface of endosomes and lysosomes. J Cell Biol 107 (1988) 2075-2086
13. Liang Y., and Gillam S. Rubella virus RNA replication is cis preferential and synthesis of negative- and positive-strand RNAs is regulated by the processing of nonstructural protein. Virology 282 (2001) 307-319
14. Atasheva S., Gorchakov R., English R., Frolov I., and Frolova E. Development of Sindbis viruses encoding nsP2/GFP chimeric proteins and their application for studying nsP2 functioning. J Virol 81 (2007) 5046-5057
15. Frolova E., Gorchakov R., Garmashova N., Atasheva S., Vergara L.A., and Frolov I. Formation of nsP3-specific protein complexes during Sindbis virus replication. J Virol 80 (2006) 4122-4134
16. Berkower I., Patel C., Ni Y., Virnik K., Xiang Z., and Spadaccini A. Targeted deletion in the beta20-beta21 loop of HIV envelope glycoprotein gp120 exposes the CD4 binding site for antibody binding. Virology 377 (2008) 330-338
17. Berzofsky J.A., and Berkower I. Immunogenicity and antigen structure. In: William Paul (Ed). Fundamental Immunology. 6th ed. (2008) Chap. 21
18. Phogat S., Svehla K., Tang M., Spadaccini A., Muller J., Mascola J., et al. Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles. Virology 373 (2008) 72-84
19. Wu L., ZhouT, Yang Z., Svehla K., O'Dell S., Louder M.K., et al. Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored Human Immunodeficiency Virus type 1 gp120 domain. J Virol 83 (2009) 5077-5086
20. Xiong C., Levis R., Shen P., Schlesinger S., Rice C.M., and Huang H.V. Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science 243 (1989) 1188-1191
21. Frolov I., Hoffman T.A., Prágai B.M., Dryga S.A., Huang H.V., Schlesinger S., et al. Alphavirus-based expression vectors: strategies and applications. Proc Natl Acad Sci USA 93 (1996) 11371-11377
22. Pushko P., Parker M., Ludwig G.V., Davis N.L., Johnston R.E., and Smith J.F. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology 239 (1997) 389-401
23. Daniel M.D., Kirchhoff F., Czajak S.C., Sehgal P.K., and Desrosiers R.C. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258 (1992) 1938-1941
24. Desrosiers R.C., Lifson J.D., Gibbs J.S., Czajak S.C., Howe A.Y., Arthur L.O., et al. Identification of highly attenuated mutants of simian immunodeficiency virus. J Virol 72 (1998) 1431-1437
25. Robert-Guroff M. Replicating and non-replicating viral vectors for vaccine development. Curr Opin Biotechnol 18 (2007) 546-556
26. Hirsch V.M. What can natural infection of African monkeys with Simian Immunodeficiency virus tell us about the pathogenesis of AIDS?. AIDS Rev 6 (2004) 40-53
27. Demberg T., Florese R.H., Heath M.J., Larsen K., Kalisz I., Kalyanaraman V.S., et al. A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques. J Virol 81 (2007) 3414-3427
28. MacDonald G.H., and Johnston R.E. Role of dendritic cell targeting in Venezuelan equine encephalitis virus pathogenesis. J Virol 74 (2000) 914-922
29. Watson J.C., Hadler S.C., Dykewicz C.A., Reef S., and Phillips L. Measles, mumps, and rubella-vaccine use and strategies for elimination of measles, rubella, and congenital rubella syndrome and control of mumps: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 47 (1998) 1-57
30. Cutts F.T., Robertson S.E., Diaz-Ortega J.L., and Samuel R. Control of rubella and congenital rubella syndrome (CRS) in developing countries. Part 1: Burden of disease from CRS. Bull WHO 75 (1997) 55-68