Lack of population diversity in commonly used human embryonic stem-cell lines

New England Journal of Medicine

Volumn 362, Issue 2, 2010, Pages 183-185

  Mosher, Jack T ^a   Pemberton, Trevor J ^a   Harter, Kristina ^a   Wang, Chaolong ^a   Buzbas, Erkan O ^a   Dvorak, Petr ^b   Simón, Carlos ^c   Morrison, Sean J ^a   Rosenberg, Noah A ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b MASARYK UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICA; ASIAN; CELL LINE; CLUSTER ANALYSIS; DRUG RESEARCH; EMBRYONIC STEM CELL; EUROPE; GENOTYPE; ISRAEL; LETTER; MIDDLE EAST; MUTATIONAL ANALYSIS; PLURIPOTENT STEM CELL; POPULATION GENETIC PARAMETERS; PRIORITY JOURNAL; REFERENCE DATABASE; RISK BENEFIT ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SPAIN;

EID: 74249090979     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc0910371     Document Type: Letter

References (5)

1. McCormick JB, Owen-Smith J, Scott CT. Distribution of human embryonic stem cell lines: who, when, and where. Cell Stem Cell 2009;4:107-10.
2. International HapMap Consortium. A second generation human haplotype map of over 3.1 million SNPs. Nature 2007;449:851-61.
3. Li JZ, Absher DM, Tang H, et al. Worldwide human relationships inferred from genome-wide patterns of variation. Science 2008;319:1100-4.
4. Jakobsson M, Scholz SW, Scheet P, et al. Genotype, haplotype, and copy-number variation in worldwide human populations. Nature 2008;451:998-1003.
5. Scott CT, McCormick JB, Owen-Smith J. And then there were two: use of hESC lines. Nat Biotechnol 2009;27:696-7.1