Capture of type 1 diabetes-susceptible HLA DR-DQ haplotypes in Japanese subjects using a tag single nucleotide polymorphism

Diabetes Care

Volumn 33, Issue 1, 2010, Pages 162-164

  Nakanishi, Koji ^a,b   Shima, Yukio ^c  

^a TORANOMON HOSPITAL   (Japan)

^b Okinaka Memorial Institute for Medical Research   (Japan)

^c KYORIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; JAPANESE; MAJOR CLINICAL STUDY; MALE; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; DIABETES MELLITUS, TYPE 1; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 74249085632     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc09-1210     Document Type: Article

References (14)

1. Mehers KL, Gillespie KM. The genetic basis for type 1 diabetes. Br Med Bull 2008; 88:115-129
2. Nakanishi K, Inoko H. Combination of HLA-A24, -DQA1*03, and -DR9 contributes to acute-onset and early complete β-cell destruction in type 1 diabetes: longitudinal study of residual β-cell function. Diabetes 2006;55:1862-1868
3. Watanabe C, Nakanishi K. Type 1 diabetes induced by interferon therapy is characterized by high titer of GAD antibodies, raised level of serum interleukin 18, and relatively preserved β cell function (Abstract). Diabetes 2008;57(Suppl. 1):A355
4. Mizuhashi S, Nakamura K, Mori Y, Noda M, Nakanishi K. Insulin allergy and immunologic insulin resistance caused by interleukin-6 in a patient with lung cancer. Diabetes Care 2006;29:1711-1712
5. de Bakker PIW, McVean G, Sabeti PC, Miretti MM, Green T, Marchini J, Ke X, Monsuur AJ, Whittaker P, Delgado M, Morrison J, Richardson A, Walsh EC, Gao X, Galver L, Hart J, Hafler DA, Pericak-Vance M, Todd JA, Daly MJ, Trowsdale J, Wijmenga C, Vyse TJ, Beck S, Murray SS, Carrington M, Gregory S, Deloukas P, Rioux JD. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet 2006;38:1166-1172
6. Naruse TK, Ando R, Nose Y, Kagiya M, Ando H, Kawata H, Nabeya N, Isshiki G, Inoko H. HLA-DRB4 genotyping by PCRRFLP: diversity in the associations between HLA-DRB4 and DRB1 alleles. Tissue Antigens 1997;49:152-159
7. Katahira M, Ishiguro T, Segawa S, Kuzuya-Nagao K, Hara I, Nishisaki T. Reevaluation of human leukocyte antigen DR-DQ haplotype and genotype in type 1 diabetes in the Japanese population. Horm Res 2008;69:284-289
8. Murao S, Makino H, Kaino Y, Konoue E, Ohashi J, Kida K, Fujii Y, Shimizu I, Kawasaki E, Fujiyama M, Kondo S, Tanaka K, Tarumi Y, Seto I, Kato K, Ohno K, Kusunoki Y, Ebisui O, Takada Y, Tanabe K, Takemoto K, Onuma H, Nishimiya T, Osawa H. Differences in the contribution of HLA-DR and -DQ haplotypes to susceptibility to adult- and childhood-onset type 1 diabetes in Japanese patients. Diabetes 2004;53:2684-2690
9. Kawabata Y, Ikegami H, Kawaguchi Y, Fujisawa T, Shintani M, Ono M, Nishino M, Uchigata Y, Lee I, Ogihara T. Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes. Diabetes 2002;51:545-551
10. Kawasaki E, Matsuura N, Eguchi K. Type 1 diabetes in Japan. Diabetologia 2006; 49:828-836
11. Park YS, She JX, Noble JA, Erlich HA, Eisenbarth GS. Transracial evidence for the influence of the homologous HLA DR-DQ haplotype on transmission of HLA DR4 haplotypes to diabetic children. Tissue Antigens 2001;57:185-191
12. Hashimoto M, Kinoshita T, Yamasaki M, Tanaka H, Imanishi T, Ihara H, Ichikawa Y, Fukunishi T. Gene frequencies and haplotypic associations within the HLA region in 916 unrelated Japanese individuals. Tissue Antigens 1994; 44:166 -173
13. Barker JM, Triolo TM, Aly TA, Baschal EE, Babu SR, Kretowski A, Rewers MJ, Eisenbarth GS. Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening. Diabetes 2008;57:3152-3155
14. Kobayashi T, Tanaka S, Harii N, Aida K, Shimura H, Ohmori M, Kanesige M, Shimada A, Mruyama T. Immunopathological and genetic features in slowly progressive insulin-dependent diabetes mellitus and latent autoimmune diabetes in adults. Ann N Y Acad Sci 2006;1079: 60-66