Differential gene expression triggered by highly cytotoxic α-Emitter-immunoconjugates in gastric cancer cells

Investigational New Drugs

Volumn 28, Issue 1, 2010, Pages 49-60

  Seidl, Christof ^a   Port, Matthias ^b,c   Apostolidis, Christos ^d   Bruchertseifer, Frank ^d   Schwaiger, Markus ^a   Senekowitsch Schmidtke, Reingard ^a   Abend, Michael ^a,c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c Bundeswehr Institute of Radiobiology   (Germany)

^d JOINT RESEARCH CENTRE   (Italy)

Author keywords

Alpha emitter 213Bi; Gastric cancer; Gene expression profiling; Radioimmunotherapy; Whole genome microarray

Indexed keywords

ANTIBODY CONJUGATE; BISMUTH 213; COMPLEMENTARY DNA; CYTOTOXIC AGENT; MONOCLONAL ANTIBODY;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOME; HUMAN; HUMAN CELL; IRRADIATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; STOMACH CANCER; UPREGULATION;

ANIMALS; ANTIBODIES, MONOCLONAL; BISMUTH; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CHROMOSOME SEGREGATION; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; GENOME, HUMAN; HUMANS; IMMUNOCONJUGATES; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RADIOISOTOPES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS; TIME FACTORS;

EID: 74149087930     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-008-9214-4     Document Type: Article

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