메뉴 건너뛰기




Volumn 39, Issue 1-2, 2009, Pages 185-198

Clozapine-induced ERK1 and ERK2 signaling in prefrontal cortex is mediated by the EGF receptor

Author keywords

Antipsychotic drug; EGF receptor; ERK; Prefrontal cortex; Schizophrenia; Signal transduction

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3,5 DI TERT BUTYL ALPHA CYANO 4 HYDROXYTHIOCINNAMAMIDE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6,7 DIMETHYL 2 PHENYLQUINOXALINE; ARIPIPRAZOLE; CARBACHOL; CLOZAPINE; EPIDERMAL GROWTH FACTOR RECEPTOR; HALOPERIDOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PROTEIN TYROSINE KINASE INHIBITOR; QUETIAPINE; RACLOPRIDE; SEROTONIN 2A AGONIST; TYRPHOSTIN A9; UNCLASSIFIED DRUG;

EID: 74149085199     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-009-9188-5     Document Type: Article
Times cited : (26)

References (40)
  • 1
    • 41149167191 scopus 로고    scopus 로고
    • Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signalregulated kinase activation
    • doi:10.1124/jpet.107.131987
    • Ahmed, M. R., Gurevich, V. V., Dalby, K. N., Benovic, J. L., & Gurevich, E. V. (2008). Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signalregulated kinase activation. The Journal of Pharmacology and Experimental Therapeutics, 325, 276-283. doi:10.1124/jpet.107.131987.
    • (2008) The Journal of Pharmacology and Experimental Therapeutics , vol.325 , pp. 276-283
    • Ahmed, M.R.1    Gurevich, V.V.2    Dalby, K.N.3    Benovic, J.L.4    Gurevich, E.V.5
  • 2
    • 2442692638 scopus 로고    scopus 로고
    • Association of EGF polymorphism with schizophrenia in Finnish men
    • doi:10.1097/00001756-200405190- 00027
    • Anttila, S., Illi, A., Kampman, O., Mattila, K. M., Lehtimaki, T., & Leinonen, E. (2004). Association of EGF polymorphism with schizophrenia in Finnish men. Neuroreport, 15, 1215-1218. doi:10.1097/00001756-200405190- 00027.
    • (2004) Neuroreport , vol.15 , pp. 1215-1218
    • Anttila, S.1    Illi, A.2    Kampman, O.3    Mattila, K.M.4    Lehtimaki, T.5    Leinonen, E.6
  • 4
    • 34247863773 scopus 로고    scopus 로고
    • The neuregulin-I/ErbB signaling system in development and disease
    • doi:10.1007/978-3-540-37107-6-1
    • Britsch, S. (2007). The neuregulin-I/ErbB signaling system in development and disease. Advances in Anatomy, Embryology, and Cell Biology, 190, 1-65. doi:10.1007/978-3-540-37107-6-1.
    • (2007) Advances in Anatomy, Embryology, and Cell Biology , vol.190 , pp. 1-65
    • Britsch, S.1
  • 5
    • 15744400492 scopus 로고    scopus 로고
    • Clozapine and the mitogen-activated protein kinase signal transduction pathway: Implications for antipsychotic actions
    • doi:10.1016/j.biopsych.2004.12.002
    • Browning, J. L., Patel, T., Brandt, P. C., Young, K. A., Holcomb, L. A., & Hicks, P. B. (2005). Clozapine and the mitogen-activated protein kinase signal transduction pathway: implications for antipsychotic actions. Biological Psychiatry, 57, 617-623. doi:10.1016/j.biopsych.2004.12.002.
    • (2005) Biological Psychiatry , vol.57 , pp. 617-623
    • Browning, J.L.1    Patel, T.2    Brandt, P.C.3    Young, K.A.4    Holcomb, L.A.5    Hicks, P.B.6
  • 6
    • 33644907147 scopus 로고    scopus 로고
    • Differential profile of antipsychotics at serotonin 5-HT1A and dopamine D2S receptors coupled to extracellular signalregulated kinase
    • doi:10.1016/j.ejphar.2006.01.027
    • Bruins Slot, L. A., De Vries, L., Newman-Tancredi, A., & Cussac, D. (2006). Differential profile of antipsychotics at serotonin 5-HT1A and dopamine D2S receptors coupled to extracellular signalregulated kinase. European Journal of Pharmacology, 534, 63-70. doi:10.1016/j.ejphar.2006.01.027.
    • (2006) European Journal of Pharmacology , vol.534 , pp. 63-70
    • Bruins Slot, L.A.1    De Vries, L.2    Newman-Tancredi, A.3    Cussac, D.4
  • 7
    • 38349111686 scopus 로고    scopus 로고
    • Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene
    • doi:10.1038/sj.mp. 4001991
    • Buxbaum, J. D., Georgieva, L., Young, J. J., Plescia, C., Kajiwara, Y., Jiang, Y., et al. (2008). Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene. Molecular Psychiatry, 13, 162-172. doi:10.1038/sj.mp. 4001991.
    • (2008) Molecular Psychiatry , vol.13 , pp. 162-172
    • Buxbaum, J.D.1    Georgieva, L.2    Young, J.J.3    Plescia, C.4    Kajiwara, Y.5    Jiang, Y.6
  • 9
    • 0036019548 scopus 로고    scopus 로고
    • Stimulation by antipsychotic agents of mitogen-activated protein kinase (MAPK) coupled to cloned, human (h) serotonin (5-HT) (1A) receptors
    • doi:10.1007/s00213-002-1043-0
    • Cussac, D., Duqueyroix, D., Newman-Tancredi, A., & Millan, M. J. (2002). Stimulation by antipsychotic agents of mitogen-activated protein kinase (MAPK) coupled to cloned, human (h) serotonin (5-HT) (1A) receptors. Psychopharmacology, 162, 168-177. doi:10.1007/s00213-002-1043-0.
    • (2002) Psychopharmacology , vol.162 , pp. 168-177
    • Cussac, D.1    Duqueyroix, D.2    Newman-Tancredi, A.3    Millan, M.J.4
  • 10
    • 0036193404 scopus 로고    scopus 로고
    • Differential effects of haloperidol and clozapine on [(3) H]cAMP binding, protein kinase A (PKA) activity, and mRNA and protein expression of selective regulatory and catalytic subunit isoforms of PKA in rat brain
    • doi:10.1124/jpet.301.1.197
    • Dwivedi, Y., Rizavi, H. S., & Pandey, G. N. (2002). Differential effects of haloperidol and clozapine on [(3) H]cAMP binding, protein kinase A (PKA) activity, and mRNA and protein expression of selective regulatory and catalytic subunit isoforms of PKA in rat brain. The Journal of Pharmacology and Experimental Therapeutics, 301, 197-209. doi:10.1124/jpet.301.1.197.
    • (2002) The Journal of Pharmacology and Experimental Therapeutics , vol.301 , pp. 197-209
    • Dwivedi, Y.1    Rizavi, H.S.2    Pandey, G.N.3
  • 11
    • 33646044696 scopus 로고    scopus 로고
    • Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase
    • doi:10.1016/j.bcp. 2006.01.020
    • Ellis, A. G., Doherty, M. M., Walker, F., Weinstock, J., Nerrie, M., Vitali, A., et al. (2006). Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase. Biochemical Pharmacology, 71, 1422-1434. doi:10.1016/j.bcp. 2006.01.020.
    • (2006) Biochemical Pharmacology , vol.71 , pp. 1422-1434
    • Ellis, A.G.1    Doherty, M.M.2    Walker, F.3    Weinstock, J.4    Nerrie, M.5    Vitali, A.6
  • 12
    • 33645096209 scopus 로고    scopus 로고
    • Long-term exposure to the atypical antipsychotic olanzapine differently up-regulates extracellular signal-regulated kinases 1 and 2 phosphorylation in subcellular compartments of rat prefrontal cortex
    • doi:10.1124/mol.105.019828
    • Fumagalli, F., Frasca, A., Sparta, M., Drago, F., Racagni, G., & Riva, M. A. (2006). Long-term exposure to the atypical antipsychotic olanzapine differently up-regulates extracellular signal-regulated kinases 1 and 2 phosphorylation in subcellular compartments of rat prefrontal cortex. Molecular Pharmacology, 69, 1366-1372. doi:10.1124/mol.105.019828.
    • (2006) Molecular Pharmacology , vol.69 , pp. 1366-1372
    • Fumagalli, F.1    Frasca, A.2    Sparta, M.3    Drago, F.4    Racagni, G.5    Riva, M.A.6
  • 13
    • 0036367363 scopus 로고    scopus 로고
    • Abnormal expression of epidermal growth factor and its receptor in the forebrain and serum of schizophrenic patients
    • doi:10.1038/sj.mp. 4001081
    • Futamura, T., Toyooka, K., Iritani, S., Niizato, K., Nakamura, R., Tsuchiya, K., et al. (2002). Abnormal expression of epidermal growth factor and its receptor in the forebrain and serum of schizophrenic patients. Molecular Psychiatry, 7, 673-682. doi:10.1038/sj.mp. 4001081.
    • (2002) Molecular Psychiatry , vol.7 , pp. 673-682
    • Futamura, T.1    Toyooka, K.2    Iritani, S.3    Niizato, K.4    Nakamura, R.5    Tsuchiya, K.6
  • 14
    • 33745912772 scopus 로고    scopus 로고
    • Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia
    • doi:10.1038/nm1418
    • Hahn, C. G., Wang, H. Y., Cho, D. S., Talbot, K., Gur, R. E., Berrettini, W. H., et al. (2006). Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nature Medicine, 12, 824-828. doi:10.1038/nm1418.
    • (2006) Nature Medicine , vol.12 , pp. 824-828
    • Hahn, C.G.1    Wang, H.Y.2    Cho, D.S.3    Talbot, K.4    Gur, R.E.5    Berrettini, W.H.6
  • 15
    • 33745684066 scopus 로고    scopus 로고
    • Neuregulin 1 and schizophrenia: Genetics, gene expression, and neurobiology
    • doi:10.1016/j.biopsych.2005.11.002
    • Harrison, P. J., & Law, A. J. (2006). Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology. Biological Psychiatry, 60, 32-140. doi:10.1016/j.biopsych.2005.11.002.
    • (2006) Biological Psychiatry , vol.60 , pp. 32-140
    • Harrison, P.J.1    Law, A.J.2
  • 16
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • doi:10.1038/sj.mp. 4001558
    • Harrison, P. J., & Weinberger, D. R. (2005). Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Molecular Psychiatry, 10, 40-68. doi:10.1038/sj.mp. 4001558.
    • (2005) Molecular Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 17
    • 29344436259 scopus 로고    scopus 로고
    • Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice
    • doi:10.1016/j.biopsych.2005. 06.006
    • Kamei, H., Nagai, T., Nakano, H., Togan, Y., Takayanagi, M., Takahashi, K., et al. (2006). Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice. Biological Psychiatry, 59, 75-84. doi:10.1016/j.biopsych.2005. 06.006.
    • (2006) Biological Psychiatry , vol.59 , pp. 75-84
    • Kamei, H.1    Nagai, T.2    Nakano, H.3    Togan, Y.4    Takayanagi, M.5    Takahashi, K.6
  • 18
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
    • Kane, J., Honigfeld, G., Singer, J., & Meltzer, H. (1988). Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Archives of General Psychiatry, 45, 789-796.
    • (1988) Archives of General Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 19
    • 0035094264 scopus 로고    scopus 로고
    • Does fast dissociation from the dopamine D (2) receptor explain the action of atypical antipsychotics?: A new hypothesis
    • doi:10.1176/appi.ajp. 158.3.360
    • Kapur, S., & Seeman, P. (2001). Does fast dissociation from the dopamine D (2) receptor explain the action of atypical antipsychotics?: A new hypothesis. The American Journal of Psychiatry, 158, 360-369. doi:10.1176/appi.ajp. 158.3.360.
    • (2001) The American Journal of Psychiatry , vol.158 , pp. 360-369
    • Kapur, S.1    Seeman, P.2
  • 21
    • 33748768220 scopus 로고    scopus 로고
    • Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia
    • doi:10.1093/schbul/sbj067
    • Lewis, S. W., Barnes, T. R., Davies, L., Murray, R. M., Dunn, G., Hayhurst, K. P., et al. (2006). Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia. Schizophrenia Bulletin, 32, 715-723. doi:10.1093/schbul/sbj067.
    • (2006) Schizophrenia Bulletin , vol.32 , pp. 715-723
    • Lewis, S.W.1    Barnes, T.R.2    Davies, L.3    Murray, R.M.4    Dunn, G.5    Hayhurst, K.P.6
  • 23
    • 23444439797 scopus 로고    scopus 로고
    • Lu, X. H., & Dwyer, D. S. (2005). Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways. Journal of Molecular Neuroscience, 27, 43-64. doi:10.1385/JMN:27:1:043.
    • Lu, X. H., & Dwyer, D. S. (2005). Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways. Journal of Molecular Neuroscience, 27, 43-64. doi:10.1385/JMN:27:1:043.
  • 24
    • 2342638276 scopus 로고    scopus 로고
    • Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38
    • doi:10.1016/j.brainres.2004.03.018
    • Lu, X. H., Bradley, R. J., & Dwyer, D. S. (2004). Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38. Brain Research, 1011, 58-68. doi:10.1016/j.brainres.2004.03.018.
    • (2004) Brain Research , vol.1011 , pp. 58-68
    • Lu, X.H.1    Bradley, R.J.2    Dwyer, D.S.3
  • 25
    • 85047698267 scopus 로고    scopus 로고
    • Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment
    • doi:10.1176/appi.ajp. 163.4.600
    • McEvoy, J. P., Lieberman, J. A., Stroup, T. S., Davis, S. M., Meltzer, H. Y., Rosenheck, R. A., et al. (2006). Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. The American Journal of Psychiatry, 163, 600-610. doi:10.1176/appi.ajp. 163.4.600.
    • (2006) The American Journal of Psychiatry , vol.163 , pp. 600-610
    • McEvoy, J.P.1    Lieberman, J.A.2    Stroup, T.S.3    Davis, S.M.4    Meltzer, H.Y.5    Rosenheck, R.A.6
  • 26
    • 0742271350 scopus 로고    scopus 로고
    • What's atypical about atypical antipsychotic drugs?
    • doi:10.1016/j.coph. 2003.09.010
    • Meltzer, H. Y. (2004). What's atypical about atypical antipsychotic drugs? Current Opinion in Pharmacology, 4, 53-57. doi:10.1016/j.coph. 2003.09.010.
    • (2004) Current Opinion in Pharmacology , vol.4 , pp. 53-57
    • Meltzer, H.Y.1
  • 27
    • 0038155088 scopus 로고    scopus 로고
    • Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum
    • doi:10.1046/j.1471- 4159.2003.01851.x
    • Pozzi, L., Hakansson, K., Usiello, A., Borgkvist, A., Lindskog, M., Greengard, P., et al. (2003). Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum. Journal of Neurochemistry, 86, 451-459. doi:10.1046/j.1471- 4159.2003.01851.x.
    • (2003) Journal of Neurochemistry , vol.86 , pp. 451-459
    • Pozzi, L.1    Hakansson, K.2    Usiello, A.3    Borgkvist, A.4    Lindskog, M.5    Greengard, P.6
  • 28
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • Prenzel, N., Zwick, E., Daub, H., Leserer, M., Abraham, R., Wallasch, C., et al. (1999). EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature, 402, 884-888.
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3    Leserer, M.4    Abraham, R.5    Wallasch, C.6
  • 30
    • 0042562048 scopus 로고    scopus 로고
    • Schizophrenia and bipolar affective disorder: Perspectives for the development of therapeutics
    • doi:10.2174/1566524033479708
    • Sundram, S., Joyce, P. R., & Kennedy, M. A. (2003). Schizophrenia and bipolar affective disorder: perspectives for the development of therapeutics. Current Molecular Medicine, 3, 393-407. doi:10.2174/1566524033479708.
    • (2003) Current Molecular Medicine , vol.3 , pp. 393-407
    • Sundram, S.1    Joyce, P.R.2    Kennedy, M.A.3
  • 31
    • 1342289413 scopus 로고    scopus 로고
    • MAPK cascade signaling and synaptic plasticity
    • doi:10.1038/nrn1346
    • Thomas, G. M., & Huganir, R. L. (2004). MAPK cascade signaling and synaptic plasticity. Nature Reviews. Neuroscience, 5, 173-183. doi:10.1038/nrn1346.
    • (2004) Nature Reviews. Neuroscience , vol.5 , pp. 173-183
    • Thomas, G.M.1    Huganir, R.L.2
  • 32
    • 0442323511 scopus 로고    scopus 로고
    • Antipsychotics regulate cyclic AMP-dependent protein kinase and phosphorylated cyclic AMP response element-binding protein in striatal and cortical brain regions in mice
    • doi:10.1016/j.neulet. 2003.11.059
    • Turalba, A. V., Leite-Morris, K. A., & Kaplan, G. B. (2004). Antipsychotics regulate cyclic AMP-dependent protein kinase and phosphorylated cyclic AMP response element-binding protein in striatal and cortical brain regions in mice. Neuroscience Letters, 357, 53-57. doi:10.1016/j.neulet. 2003.11.059.
    • (2004) Neuroscience Letters , vol.357 , pp. 53-57
    • Turalba, A.V.1    Leite-Morris, K.A.2    Kaplan, G.B.3
  • 34
    • 0037088589 scopus 로고    scopus 로고
    • ERK activation by G-protein-coupled receptors in mouse brain is receptor identity-specific
    • doi:10.1074/jbc. M108309200
    • Vanhoose, A. M., Emery, M., Jimenez, L., & Winder, D. G. (2002). ERK activation by G-protein-coupled receptors in mouse brain is receptor identity-specific. The Journal of Biological Chemistry, 277, 9049-9053. doi:10.1074/jbc. M108309200.
    • (2002) The Journal of Biological Chemistry , vol.277 , pp. 9049-9053
    • Vanhoose, A.M.1    Emery, M.2    Jimenez, L.3    Winder, D.G.4
  • 35
    • 2342509663 scopus 로고    scopus 로고
    • The role of G-protein coupled receptors and associated proteins in receptor tyrosine kinase signal transduction
    • doi:10.1016/j.semcdb.2003.12.020
    • Waters, C., Pyne, S., & Pyne, N. J. (2004). The role of G-protein coupled receptors and associated proteins in receptor tyrosine kinase signal transduction.. Seminars in Cell & Developmental Biology, 15, 309-323. doi:10.1016/j.semcdb.2003.12.020.
    • (2004) Seminars in Cell & Developmental Biology , vol.15 , pp. 309-323
    • Waters, C.1    Pyne, S.2    Pyne, N.J.3
  • 36
    • 0344141457 scopus 로고    scopus 로고
    • Distribution of clozapine and desmethylclozapine between blood and brain in rats
    • doi:10.1016/S0924-977X (98) 00036-4
    • Weigmann, H., Hartter, S., Fischer, V., Dahmen, N., & Hiemke, C. (1999). Distribution of clozapine and desmethylclozapine between blood and brain in rats. European Neuropsychopharmacology, 9, 253-256. doi:10.1016/S0924-977X (98) 00036-4.
    • (1999) European Neuropsychopharmacology , vol.9 , pp. 253-256
    • Weigmann, H.1    Hartter, S.2    Fischer, V.3    Dahmen, N.4    Hiemke, C.5
  • 37
    • 0032529710 scopus 로고    scopus 로고
    • Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress
    • White, A. R., Zheng, H., Galatis, D., Maher, F., Hesse, L., Multhaup, G., et al. (1998). Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress. The Journal of Neuroscience, 18, 6207-6217.
    • (1998) The Journal of Neuroscience , vol.18 , pp. 6207-6217
    • White, A.R.1    Zheng, H.2    Galatis, D.3    Maher, F.4    Hesse, L.5    Multhaup, G.6
  • 38
    • 1942541169 scopus 로고    scopus 로고
    • The role of epidermal growth factor and its receptors in mammalian CNS
    • doi:10.1016/j.cytogfr. 2004.01.004
    • Wong, R. W., & Guillaud, L. (2004). The role of epidermal growth factor and its receptors in mammalian CNS. Cytokine & Growth Factor Reviews, 15, 147-156. doi:10.1016/j.cytogfr. 2004.01.004.
    • (2004) Cytokine & Growth Factor Reviews , vol.15 , pp. 147-156
    • Wong, R.W.1    Guillaud, L.2
  • 39
    • 34447293701 scopus 로고    scopus 로고
    • Quetiapine attenuates the depressive and anxiolytic-like behavioural changes induced by global cerebral ischemia in mice
    • doi:10.1016/j. bbr.2007.05.002
    • Yan, B., He, J., Xu, H., Zhang, Y., Bi, X., Thakur, S., et al. (2007). Quetiapine attenuates the depressive and anxiolytic-like behavioural changes induced by global cerebral ischemia in mice. Behavioural Brain Research, 182, 36-41. doi:10.1016/j. bbr.2007.05.002.
    • (2007) Behavioural Brain Research , vol.182 , pp. 36-41
    • Yan, B.1    He, J.2    Xu, H.3    Zhang, Y.4    Bi, X.5    Thakur, S.6
  • 40
    • 23844470651 scopus 로고    scopus 로고
    • Aripiprazole increases dopamine but not noradrenaline and serotonin levels in the mouse prefrontal cortex
    • Zocchi, A., Fabbri, D., & Heidbreder, C. A. (2005). Aripiprazole increases dopamine but not noradrenaline and serotonin levels in the mouse prefrontal cortex. Neuroscience Letters, 387, 157-161.
    • (2005) Neuroscience Letters , vol.387 , pp. 157-161
    • Zocchi, A.1    Fabbri, D.2    Heidbreder, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.