What is the significance of a high cycle threshold positive is481 PCR for bordetella pertussis?

Pediatric Infectious Disease Journal

Volumn 28, Issue 12, 2009, Pages 1143-

  Papenburg, Jesse ^a,b   Fontela, Patricia ^c  

^a MONTREAL CHILDREN S HOSPITAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL GENE; BACTERIUM DETECTION; BORDETELLA PERTUSSIS; CORRELATION ANALYSIS; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; HUMAN; IS481 GENE; LETTER; MIXED INFECTION; PERTUSSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY;

EID: 74049160699     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181bd4e1f     Document Type: Letter

References (3)

1. Waters V, Jamieson F, Richardson SE, et al. Outbreak of atypical pertussis detected by poly-merase chain reaction in immunized preschool-aged children. Pediatr Infect Dis J. 2009;28: 582-587.
2. Guthrie JL, Seah C, Brown S, et al. Use of Bordetella pertussis BP3385 to establish a cutoff value for an IS481-targeted real-time PCR assay. J Clin Microbiol. 2008;46:3798-3799.
3. Loeffelholz MJ, Thompson CJ, Long KS, et al. Comparison of PCR, culture, and direct fluorescent-antibody testing for detection of Bor-detella pertussis. J Clin Microbiol. 1999;37: 2872-2876