Blood culture and bacteremia predictors in infants less than three months of age with fever without source

Pediatric Infectious Disease Journal

Volumn 29, Issue 1, 2010, Pages 43-47

  Gómez, Borja ^a   Mintegi, Santiago ^a   Benito, Javier ^a   Egireun, Andere ^a   Garcia, Diego ^a   Astobiza, Eider ^a  

^a HOSPITAL DE CRUCES   (Spain)

Author keywords

Bacteremia; Blood culture; Diagnostic tests; Fever; Young infant

Indexed keywords

C REACTIVE PROTEIN;

ACUTE OTITIS MEDIA; ARTICLE; BACTEREMIA; BACTERIAL GROWTH; BACTERIAL MENINGITIS; BACTERIUM ISOLATE; BLOOD CULTURE; CELLULITIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; EMERGENCY WARD; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FEMALE; HUMAN; INFANT; INFECTION RISK; KLEBSIELLA PNEUMONIAE; LEUKOCYTE COUNT; LEUKOCYTURIA; MAJOR CLINICAL STUDY; MALE; NEISSERIA MENINGITIDIS; NEUTROPHIL COUNT; NONHUMAN; PEDIATRIC WARD; PRIORITY JOURNAL; PYREXIA IDIOPATHICA; SEPSIS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS PNEUMONIAE; URINARY TRACT INFECTION; URINE CULTURE;

EID: 74049115553     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181c6dd14     Document Type: Article

References (33)

1. Nelson DS, Walsh K, Fleisher GR. Spectrum and frequency of pediatric illness presenting to a general community hospital emergency department. Pediatrics. 1992;90(1 pt 1):5-10.
2. Massin MM, Montesanti J, Gerard P, et al. Spectrum and frequency of illness presenting to a pediatric emergency department. Acta Clin Belg. 2006;61:161-165.
3. Ishimine P. Fever without source in children 0 to 36 months of age. Pediatr Clin North Am. 2006;53:167-194.
4. Baskin MN. The prevalence of serious bacterial infections by age in febrile infants during the first 3 months of life. Pediatr Ann. 1993;22:462-466.
5. Slater M, Krug SE. Evaluation of the infant with fever without source: an evidence based approach. Emerg Med Clin North Am. 1999;17:97-126.
6. Harper MB. Update on the management of the febrile infant. Clin Pediatr Emerg Med. 2004;5:5-12.
7. Baker MD, Bell LM. Unpredictability of serious bacterial illness in febrile infants from birth to 1 month of age. Arch Pediatr Adolesc Med. 1999;153: 508-511.
8. Bachur RG, Harper MB. Predictive model for serious bacterial infections among infants younger than 3 months of age. Pediatrics. 2001;108:311-316.
9. Bema K, ChB M, Harper MB. Identifying febrile young infants with bacteremia: is the peripheral white blood cell count an accurate screen? Ann Emerg Med. 2003;42:216-225.
10. American College of Emergency Physicians Clinical Committee; American College of Emergency Physicians Clinical Policies Subcommittee on Pediatric Fever. Clinical policy for children younger than three years presenting to the emergency department with fever. Ann Emerg Med. 2003;42:530-545.
11. Baraff LJ. Editorial: clinical policy for children younger than three years presenting to the emergency department with fever. Ann Emerg Med. 2003;42:546-549.
12. Cincinnati Children's Hospital medical Center. Fever of uncertain source in infants 60 days of age or less. Available at: http://www.cincinnatichildrens. org/svc/alpha/h/health-policy/ev-based/fever-0-60-days.htm. Accessed June 2003.
13. Baker MD, Bell LM, Avner JR. The efficacy of routine outpatient management without antibiotics of fever in selected infants. Pediatrics. 1999; 103:627-631.
14. Kourtis AP, Sullivan DT, Sathian U. Practice guidelines for the management of febrile infants less than 90 days of age at the ambulatory network of a large pediatric health care system in the United States: summary of new evidence. Clin Pediatr. 2004;43:11-16.
15. Pena BM, Harper MB, Fleischer GR. Occult bacteremia with group B streptococci in an outpatient setting. Pediatrics. 1998;102(1 pt 1):67-72.
16. Schrag SJ, Zywicki S, Farley MM, et al. Group B streptococcal disease in the era of intrapartum antibiotic prophylaxis. N Engl J Med. 2000;342:15-20.
17. Centers for Disease Control and Prevention (CDC). Early-onset and late-onset neonatal group B streptococcal disease-United States, 1996-2004. Morb Mortal Wkly Rep. 2005;54:1205-1208.
18. Phares CR, Lynfield R, Farley MM. Epidemiology of invasive group B streptococcal disease in the United States, 1999-2005. JAMA. 2008;299: 2055-2065.
19. Raynor BD. Routine ultrasound in pregnancy. Clin Obstet Gynecol. 2003; 46:882-889.
20. Sairam S, Al-Habib A, Sasson S, et al. Natural history of fetal hydrone-phrosis diagnosed on mid-trimester ultrasound. Ultrasound Obstet Gynecol. 2001;17:191-196.
21. Poehling KM, Talbot TR, Griffin MR, et al. Invasive pneumococcal disease among infants before and after introduction of pneumococcal conjugate vaccine. JAMA. 2006;295:1668-1674.
22. Grupo de trabajo de codificación diagnóstica de la Sociedad de Urgencias de Pediatría de la AEP. Codificación diagnóstica en Urgencias de Pediatría. Available at: http://www.seup.org/seup/html/gtrabajo/cod-diagnostica.htm. Accessed December 8, 2002.
23. Hooker EA, Smith SW, Miles T, et al. Subjective assessment of fever by parents: comparison with measurement by noncontact tympanic thermometer and calibrated rectal glass mercury thermometer. Ann Emerg Med. 1996;28:313-317.
24. Graneto JW, Soglin DF. Maternal screening of childhood fever by palpation. Pediatr Emerg Care. 1996;12:183-184.
25. Shaikh N, Morone NE, Boost JE, et al. Prevalence of urinary tract infection in childhood: a meta-analysis. Pediatr Infect Dies J. 2008;27:302-308.
26. Bonacorsi S, Houdouin V, Mariani-Kurkdjian P, et al. Comparative prevalence of virulence factors in Escherichia coli causing urinary tract infection in male infants with and without bacteremia. J Clin Microbiol. 2006;44:1156-1158.
27. Bachur RG, Caputo GL. Bacteremia and meningitis among infants with urinary tract infections. Pediatr Emerg Care. 1995;11:280-284.
28. Hsiao AL, Baker MD. Fever in the new millennium: a review of recent studies of markers of serious bacterial infection in febrile children. Curr Opin Pediatr. 2005;17:56-61.
29. Lacour AG, Gervaix A, Zamora SA, et al. Procalcitonin, IL-6, IL-8, IL-1 receptor antagonist and C-reactive protein as identifiers of serious bacterial infections in children with fever without localising signs. Eur J Pediatr. 2001;160:95-100.
30. Fernández A, Luaces C, García JJ, et al. Procalcitonin in pediatric emergency departments for the early diagnosis of invasive bacterial infections in febrile infants: results of a multicenter study and utility of a rapid qualitative test for this marker. Pediatr Infect Dis J. 2003;22:895-903.
31. Andreola B, Bressan S, Callegaro S, et al. Procalcitonin and C-reactive protein as diagnostic markers of severe bacterial infections in febrile infants and children in the emergency department. Pediatr Infect Dis J. 2007;26:672-677.
32. Arkader R, Troster EJ, Lopes MR, et al. Procalcitonin does discriminate between sepsis and systemic inflammatory response syndrome. Arch Dis Child. 2006;91:117-120.
33. Maniaci V, Dauber A, Weiss S, et al. Procalcitonin in young febrile infants for the detection of serious bacterial infections. Pediatrics. 2008;122:701-710.