Editorial: The truth about inherited thrombophilias and pregnancy

Obstetrics and Gynecology

Volumn 115, Issue 1, 2010, Pages 2-4

  Branch, D Ware ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); LOW MOLECULAR WEIGHT HEPARIN; PROTHROMBIN A;

ANTIPHOSPHOLIPID SYNDROME; CLINICAL TRIAL; DISEASE ASSOCIATION; EDITORIAL; FIRST TRIMESTER PREGNANCY; GENE MUTATION; HETEROZYGOTE; HUMAN; INFLAMMATION; INTRAUTERINE GROWTH RETARDATION; METHODOLOGY; NEWBORN DEATH; NONHUMAN; PREECLAMPSIA; PREGNANCY; PREGNANCY OUTCOME; PRIORITY JOURNAL; RISK; SECOND TRIMESTER ABORTION; SEPSIS; SOLUTIO PLACENTAE; STILLBIRTH; THROMBOPHILIA; THROMBOSIS; ADULT; FEMALE; GENETICS; NOTE; PREGNANCY COMPLICATION; RISK ASSESSMENT;

ADULT; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREGNANCY OUTCOME; RESEARCH DESIGN; RISK ASSESSMENT; THROMBOPHILIA;

EID: 74049112891     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/AOG.0b013e3181c879ca     Document Type: Editorial

References (10)

1. Said JM, Higgins JR, Moses EK, Walker SP, Borg AJ, Monagle PT, et al. Inherited thrombophilia polymorphisms and pregnancy outcomes in nulliparous women. Obstet Gynecol 2009;115:5-13.
2. Silver RM, Zhao Y, Spong CY, Sibai B, Wendel G, Wenstrom K, et al. Prothrombin gene G20210A mutation and obstetric complications. Obstet Gynecol 2009;115:14-20.
3. Infante-Rivard C, Rivard GE, Yotov WV, Genin E, Guiguet M, Weinberg C, et al. Absence of association of thrombophilia polymorphisms with intrauterine growth restriction. N Engl J Med 2002;347:19-25. (Pubitemid 34728953)
4. Flacco F, You W, Grobman W. Genetic thrombophilias and intrauterine growth restriction: a meta-analysis. Obstet Gynecol 2009;113:1206-1216
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6. Branch DW, Khamashta M. Antiphospholipid syndrome. In Queenan JT, editor. High-risk pregnancy. Washington, DC: American College of Obstetricians and Gynecologists; 2007. p. 60-72.
7. Salmon JE, Girardi G. Antiphospholipid antibodies and pregnancy loss: a disorder of inflammation. J Reprod Immunol 2008;77:51-56
8. Girardi G, Redecha P, Salmon JE. Heparin prevents antiphos-pholipid antibody-induced fetal loss by inhibiting complement activation. Nature Med 2004;10:1222-1226
9. Farquharson RG, Quenby S, Greaves M. Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment. Obstet Gynecol 2002;100:3:408-413
10. Laskin CA, Spitzer KA, Clark CA, Crowther MR, Ginsberg JS, Hawker GA, et al. Low molecular weight heparin and aspirin for recurrent pregnancy loss: results from the randomized, controlled HepASA Trial. J Rheumatol 2009;36: 279-287