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Volumn 21, Issue 6, 2009, Pages 507-515

Predicting anthracycline benefit: Have we made any progress?

Author keywords

Anthracycline; Biomarker; Breast cancer; HER 2; Topoisomerase ii

Indexed keywords

ANTHRACYCLINE DERIVATIVE; BIOLOGICAL MARKER; CARBOPLATIN; CYCLOPHOSPHAMIDE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; FLUOROURACIL; MELPHALAN; METHOTREXATE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRASTUZUMAB; VINBLASTINE; ANTHRACYCLINE; DNA BINDING PROTEIN; DNA TOPOISOMERASE II ALPHA; TUMOR ANTIGEN; TUMOR MARKER;

EID: 74049111479     PISSN: 10408746     EISSN: None     Source Type: Journal    
DOI: 10.1097/CCO.0b013e328331a501     Document Type: Review
Times cited : (11)

References (67)
  • 1
    • 34548144717 scopus 로고    scopus 로고
    • Multiagent chemotherapy for early breast cancer
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group: multiagent chemotherapy for early breast cancer. Cochrane Database Syst Rev 1 :CD000487, 2002.
    • (2002) Cochrane Database Syst Rev , vol.1
  • 3
    • 34547617889 scopus 로고    scopus 로고
    • BRCA1- And BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II
    • DOI 10.1158/0008-5472.CAN-07-0601
    • Treszezamsky AD, Kachnic LA, Feng Z, et al. BRCA1- and BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II. Cancer Res 2007; 67:7078-7081. (Pubitemid 47206532)
    • (2007) Cancer Research , vol.67 , Issue.15 , pp. 7078-7081
    • Treszezamsky, A.D.1    Kachnic, L.A.2    Feng, Z.3    Zhang, J.4    Tokadjian, C.5    Powell, S.N.6
  • 4
    • 62449090881 scopus 로고    scopus 로고
    • Guidelines for human epidermal growth factor receptor 2 testing: Biologic and methodologie considerations
    • Sauter G, Lee J, Bartlett J, et al. Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologie considerations. J Clin One 2009; 8:1323-1333.
    • (2009) J Clin One , vol.8 , pp. 1323-1333
    • Sauter, G.1    Lee, J.2    Bartlett, J.3
  • 6
    • 33444464678 scopus 로고    scopus 로고
    • Focal HER2/neu amplified clones partially account for discordance between immunohistochemistry and fluorescence in-situ hybridization results: Data from NCCTG N9831 lntergroup Adjuvant Trial
    • [abstract]
    • Miller DV, Jenkins RB, Lingle WL, et al. Focal HER2/neu amplified clones partially account for discordance between immunohistochemistry and fluorescence in-situ hybridization results: data from NCCTG N9831 lntergroup Adjuvant Trial. Proc Am Soc Clin Oncol 2004; 568 [abstract].
    • (2004) Proc Am Soc Clin Oncol , pp. 568
    • Miller, D.V.1    Jenkins, R.B.2    Lingle, W.L.3
  • 9
    • 0025063119 scopus 로고
    • Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: Results from the National Surgical Adjuvant Breast and Bowel Project B-15
    • Fisher B, Brown AM, Dimitrov NV, et al. Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: results from the National Surgical Adjuvant Breast and Bowel Project B-15. J Clin Oncol 1990; 8:1483-1496.
    • (1990) J Clin Oncol , vol.8 , pp. 1483-1496
    • Fisher, B.1    Brown, A.M.2    Dimitrov, N.V.3
  • 10
    • 0003298825 scopus 로고    scopus 로고
    • HER2 expression and anthracycline effect: Results from the Naples GUN3 randomised trial
    • [abstract]
    • De Laurentiis M, Caputo F, Massarelli E, et al. HER2 expression and anthracycline effect: results from the Naples GUN3 randomised trial. Proc Am Soc Clin Oncol 2001 ; 133 [abstract].
    • (2001) Proc Am Soc Clin Oncol , pp. 133
    • De Laurentiis, M.1    Caputo, F.2    Massarelli, E.3
  • 11
    • 0036091354 scopus 로고    scopus 로고
    • HER-2 amplification and topoisomerase IIα gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
    • Di Leo A, Gancberg D, Larsimont D, et al. HER-2 amplification and topoisomerase II alpha gene aberrations as predictive markers In node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin Cancer Res 2002; 8:1107-1116. (Pubitemid 34517647)
    • (2002) Clinical Cancer Research , vol.8 , Issue.5 , pp. 1107-1116
    • Di Leo, A.1    Gancberg, D.2    Larsimont, D.3    Tanner, M.4    Jarvinen, T.5    Rouas, G.6    Dolci, S.7    Leroy, J.-Y.8    Paesmans, M.9    Isola, J.10    Piccart, M.J.11
  • 13
    • 32944475493 scopus 로고    scopus 로고
    • Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group
    • DOI 10.1200/JCO.2005.11.007
    • Knoop AS, Knudsen H, Balslev E, et al. Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers In primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil. J Clin Oncol 2005; 23:7483-7490. (Pubitemid 46291811)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.30 , pp. 7483-7490
    • Knoop, A.S.1    Knudsen, H.2    Balslev, E.3    Rasmussen, B.B.4    Overgaard, J.5    Nielsen, K.V.6    Schonau, A.7    Gunnarsdottir, K.8    Olsen, K.E.9    Mouridsen, H.10    Ejlertsen, B.11
  • 15
    • 33646681444 scopus 로고    scopus 로고
    • HER2 and responsiveness of breast cancer to adjuvant chemotherapy
    • Pritchard KI, Shepherd LE, O'Malley FP, et al. HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med 2006; 354:2103-2111.
    • (2006) N Engl J Med , vol.354 , pp. 2103-2111
    • Pritchard, K.I.1    Shepherd, L.E.2    O'Malley, F.P.3
  • 16
    • 4243739866 scopus 로고    scopus 로고
    • C-erbB2 overexpression and treatment outcome in a randomized trial comparing adjuvant CMF and AC in equitoxic regiment in breast cancer
    • [abstract]
    • Petruzelka L, Pribylova O, Vedralova J, et al. C-erbB2 overexpression and treatment outcome In a randomized trial comparing adjuvant CMF and AC In equitoxic regiment In breast cancer. Proc Am Soc Clin Oncol 2000:534 [abstract].
    • (2000) Proc Am Soc Clin Oncol , pp. 534
    • Petruzelka, L.1    Pribylova, O.2    Vedralova, J.3
  • 17
    • 0000286972 scopus 로고    scopus 로고
    • HER2 overexpression as a predictor of survival in a trial comparing adjuvant FAC and CMF in breast cancer
    • [abstract]
    • Vera R, Albanell, Lirola JL, et al. HER2 overexpression as a predictor of survival In a trial comparing adjuvant FAC and CMF In breast cancer. Proc Am Soc Clin Oncol 1999:265 [abstract].
    • (1999) Proc Am Soc Clin Oncol , pp. 265
    • Vera, R.1    Albanell Lirola, J.L.2
  • 18
    • 65549158566 scopus 로고    scopus 로고
    • Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy
    • O'Malley F, Chia S, Tu D, et al. Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy. J Natl Cancer Inst 2009; 101:644650.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 644650
    • O'Malley, F.1    Chia, S.2    Tu, D.3
  • 19
    • 0032538050 scopus 로고    scopus 로고
    • ErbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer
    • Thor AD, Berry DA, Budman DR, et al. ErbB-2, p53, and efficacy of adjuvant therapy In lymph node-positive breast cancer. J Natl Cancer Inst 1998; 90:1346-1360.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1346-1360
    • Thor, A.D.1    Berry, D.A.2    Budman, D.R.3
  • 20
    • 33744969590 scopus 로고    scopus 로고
    • Topoisomerase IIα gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Cancer Group Trial 9401
    • Tanner M, Isola J, Wiklund T, et al. Topoisomerase IIα gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy In HER-2/neu-amplified breast cancer: Scandinavian Breast Cancer Group Trial 9401. J Clin Oncol 2006; 24:2428-2436.
    • (2006) J Clin Oncol , vol.24 , pp. 2428-2436
    • Tanner, M.1    Isola, J.2    Wiklund, T.3
  • 21
    • 54849441046 scopus 로고    scopus 로고
    • Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trials
    • Bartlett JMS, Munro AF, Cameron DA, et al. Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines In the BR9601 adjuvant breast cancer chemotherapy trials. J Clin Oncol 2008; 26:5027-5035.
    • (2008) J Clin Oncol , vol.26 , pp. 5027-5035
    • Bartlett, J.M.S.1    Munro, A.F.2    Cameron, D.A.3
  • 22
    • 38049181708 scopus 로고    scopus 로고
    • Anthracyclines in the treatment of HER2negative breast cancer. [Editorial]
    • Paik S, Taniyama Y, Geyer C. Anthracyclines In the treatment of HER2negative breast cancer. [Editorial]. J Natl Cancer Inst 2008; 100:6-8.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 6-8
    • Paik, S.1    Taniyama, Y.2    Geyer, C.3
  • 25
    • 33947317453 scopus 로고    scopus 로고
    • BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC→T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC→TH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients
    • [abstract]
    • Slamon D, Elermann W, Robert N, et al. BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC→T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC→TH) with docetaxel, carboplatin and trastuzumab (TCH) In Her2neu positive early breast cancer patients. San Antonio Breast Cancer Symposium 2006:52 [abstract].
    • (2006) San Antonio Breast Cancer Symposium , pp. 52
    • Slamon, D.1    Elermann, W.2    Robert, N.3
  • 26
    • 0034900175 scopus 로고    scopus 로고
    • Induction of topoisomerase II activity after ErbB2 activation is associated with a differential response to breast cancer chemotherapy
    • Harris LN, Yang L, Liotcheva V, et al. Induction of topoisomerase II activity after ErbB2 activation Is associated with a differential response to breast cancer chemotherapy. Clin Cancer Res 2001; 7:1497-1504. (Pubitemid 32708611)
    • (2001) Clinical Cancer Research , vol.7 , Issue.6 , pp. 1497-1504
    • Harris, L.N.1    Yang, L.2    Liotcheva, V.3    Pauli, S.4    Iglehart, J.D.5    Colvin, O.M.6    Tao Shih, H.7
  • 27
    • 41649102048 scopus 로고    scopus 로고
    • Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
    • Liedtke C, Mazouni C, Hess KR, et al. Response to neoadjuvant therapy and long-term survival In patients with triple-negative breast cancer. J Clin One 2008; 26:1275-1281.
    • (2008) J Clin One , vol.26 , pp. 1275-1281
    • Liedtke, C.1    Mazouni, C.2    Hess, K.R.3
  • 29
    • 0032189276 scopus 로고    scopus 로고
    • Physiological regulation of eukaryotic topoisomerase II
    • Isaacs RJ, Davies SL, Sandi Ml, et al. Physiological regulation of eukaryotic topoisomerase II. Biochim Biophys Acta 1998; 1400:121-137.
    • (1998) Biochim Biophys Acta , vol.1400 , pp. 121-137
    • Isaacs, R.J.1    Davies, S.L.2    Ml, S.3
  • 31
    • 16644362006 scopus 로고    scopus 로고
    • Correlation between topoisomerase-II alpha gene amplification and protein expression in HER-2 amplified breast cancer
    • Durbecq V, Desmedt C, Paesmans M, et al. Correlation between topoisomerase-II alpha gene amplification and protein expression in HER-2 amplified breast cancer. Int J Oncol 2004; 25:1473-1479.
    • (2004) Int J Oncol , vol.25 , pp. 1473-1479
    • Durbecq, V.1    Desmedt, C.2    Paesmans, M.3
  • 32
    • 1542343905 scopus 로고    scopus 로고
    • Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein In human breast tumor samples
    • DOI 10.1002/gcc.20008
    • Mueller RE, Parkes RK, Andrulis I, O'Malley FP. Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein In human breast tumor samples. Genes Chromosomes Cancer 2004; 39:288-297. (Pubitemid 38326310)
    • (2004) Genes Chromosomes and Cancer , vol.39 , Issue.4 , pp. 288-297
    • Mueller, R.E.1    Parkes, R.K.2    Andrulis, I.3    O'Malley, F.P.4
  • 33
    • 13844281018 scopus 로고    scopus 로고
    • Identification and validation of prognostic markers in breast cancer with the complementary use of array-CGH and tissue microarrays
    • DOI 10.1002/path.1694
    • Callagy G, Pharoah P, Chin SF, et al. Identification and validation of prognostic markers In breast cancer with complementary use of array-CGH and tissue microarrays. J Pathol 2005; 205:388-396. (Pubitemid 40253928)
    • (2005) Journal of Pathology , vol.205 , Issue.3 , pp. 388-396
    • Callagy, G.1    Pharoah, P.2    Chin, S.-F.3    Sangan, T.4    Daigo, Y.5    Jackson, L.6    Caldas, C.7
  • 34
    • 0031775808 scopus 로고    scopus 로고
    • Predictive value of topoisomerase IIα and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
    • Jarvinen TA, Holli K, Kuukasjarvi T, Isola JJ. Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy In advanced breast cancer. Br J Cancer 1998; 77:2267-2273. (Pubitemid 28263952)
    • (1998) British Journal of Cancer , vol.77 , Issue.12 , pp. 2267-2273
    • Jarvinen, T.A.H.1    Holli, K.2    Kuukasjarvi, T.3    Isola, J.J.4
  • 35
    • 0029665095 scopus 로고    scopus 로고
    • Expression of topoisomerase IIα is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer
    • Jarvinen TA, Kononen J, Pelto-Huikko M, Isola J. Expression of topoisomerase II alpha Is associated with rapid cell proliferation, aneuploidy, and c-erbB2 over expression In breast cancer. Am J Pathol 1996; 148:2073-2082. (Pubitemid 26170530)
    • (1996) American Journal of Pathology , vol.148 , Issue.6 , pp. 2073-2082
    • Jarvinen, T.A.H.1    Kononen, J.2    Pelto-Huikko, M.3    Isola, J.4
  • 37
    • 55549097827 scopus 로고    scopus 로고
    • Anthracyclines: The first generation of cytotoxic targeted agents? A possible dream
    • Di Leo A, Moretti E. Anthracyclines: the first generation of cytotoxic targeted agents? A possible dream. j Clin Oncol 2008; 31:5027-5035.
    • (2008) J Clin Oncol , vol.31 , pp. 5027-5035
    • Di Leo, A.1    Moretti, E.2
  • 38
    • 70249085601 scopus 로고    scopus 로고
    • Topoisomerase IIα amplification does not predict benefit from dose-intense cyclophosphamide, doxorubicin, and fluorouracil therapy in HER2-amplified early breast cancer: Results of CALGB 8541/150013
    • Harris LN, Broadwater G, Abu-Khalaf M, et al. Topoisomerase IIα amplification does not predict benefit from dose-intense cyclophosphamide, doxorubicin, and fluorouracil therapy In HER2-amplified early breast cancer: Results of CALGB 8541/150013. J Clin Oncol 2009; 21:3430-3436.
    • (2009) J Clin Oncol , vol.21 , pp. 3430-3436
    • Harris, L.N.1    Broadwater, G.2    Abu-Khalaf, M.3
  • 39
    • 76649103646 scopus 로고    scopus 로고
    • A meta-analysis of phase III trials evaluating the predictive value of HER2 and topoisomerase II alpha in early breast cancer patients treated with CMF or anthracycline-based adjuvant therapy
    • [abstract].
    • Di Leo A, Isola J, Piette F, et al. A meta-analysis of phase III trials evaluating the predictive value of HER2 and topoisomerase II alpha in early breast cancer patients treated with CMF or anthracycline-based adjuvant therapy. San Antonio Breast Cancer Symposium 2008:705 [abstract].
    • (2008) San Antonio Breast Cancer Symposium , pp. 705
    • Di Leo, A.1    Isola, J.2    Piette, F.3
  • 40
    • 0030626492 scopus 로고    scopus 로고
    • Heterogeneous expression of DNA topoisomerase II alpha isoforms in tumor cell lines
    • Mo YY, Beck WT. Heterogeneous expression of DNA topoisomerase II alpha isoforms in tumor cell lines. Oncol Res 1997; 9:193-204.
    • (1997) Oncol Res , vol.9 , pp. 193-204
    • Mo, Y.Y.1    Beck, W.T.2
  • 41
    • 0037757681 scopus 로고    scopus 로고
    • Identification of functional nuclear export sequences in human topoisomerase IIα and beta
    • DOI 10.1016/S0006-291X(03)01077-5
    • Mirski SE, Bielawski JC, Cole SP. Identification of functional nuclear export sequences In human topoisomerase II alpha and beta. Biochem Biophys Res Commun 2003; 306:905-911. (Pubitemid 36776215)
    • (2003) Biochemical and Biophysical Research Communications , vol.306 , Issue.4 , pp. 905-911
    • Mirski, S.E.L.1    Bielawski, J.C.2    Cole, S.P.C.3
  • 42
    • 4344627104 scopus 로고    scopus 로고
    • Human topoisomerase IIα nuclear export is mediated by two CRM-1-dependent nuclear export signals
    • DOI 10.1242/jcs.01147
    • Turner JG, Engel R, Derderian JA, et al. Human topoisomerase II alpha nuclear export Is mediated by two CRM-1 -dependent nuclear export signals. J Cell Sci 2004; 117:3061-3071. (Pubitemid 39117680)
    • (2004) Journal of Cell Science , vol.117 , Issue.14 , pp. 3061-3071
    • Turner, J.G.1    Engel, R.2    Derderian, J.A.3    Jove, R.4    Sullivan, D.M.5
  • 43
    • 0034667463 scopus 로고    scopus 로고
    • Changes in subcellular distribution of topoisomerase IIα correlate with etoposide resistance in multicell spheroids and xenograft tumors
    • Oloumi A, MacPhail SH, Johnston PJ, et al. Changes in subcellular distribution of topoisomerase II alpha correlate with etoposide resistance in multicell spheroid and xenograft tumours. Cancer Res 2000; 60:5747-5753. (Pubitemid 30808310)
    • (2000) Cancer Research , vol.60 , Issue.20 , pp. 5747-5753
    • Oloumi, A.1    MacPhail, S.H.2    Johnston, P.J.3    Banath, J.P.4    Olive, P.L.5
  • 44
    • 0033865826 scopus 로고    scopus 로고
    • Ectopic expression of human topoisomerase II alpha fragments and etoposide resistance in mammalian cells
    • Ernst Al, Soltermann A, Sigrist JA, et al. Ectopic expression of human topoisomerase II alpha fragments and etoposide resistance in mammalian cells. Int J Cancer 2000; 88:99-107.
    • (2000) Int J Cancer , vol.88 , pp. 99-107
    • Al, E.1    Soltermann, A.2    Sigrist, J.A.3
  • 46
    • 55549143664 scopus 로고    scopus 로고
    • AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma
    • Gustavson MD, Molinaro AM, Tedesch G, et al. AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma. Arch Pathol Lab Med 2008; 132:17461752.
    • (2008) Arch Pathol Lab Med , vol.132 , pp. 17461752
    • Gustavson, M.D.1    Molinaro, A.M.2    Tedesch, G.3
  • 47
    • 70449716281 scopus 로고    scopus 로고
    • Predicting the efficacy of anthracyclines in breast cancer (BC) patients: Results of the neoadjuvant TOP trial
    • [abstract]
    • Desmedt C, Azambuja E, Larsimont D, et al. Predicting the efficacy of anthracyclines In breast cancer (BC) patients: Results of the neoadjuvant TOP trial. Proc Am Soc Clin Oncol 2009:523 [abstract].
    • (2009) Proc Am Soc Clin Oncol , pp. 523
    • Desmedt, C.1    Azambuja, E.2    Larsimont, D.3
  • 48
    • 53149089444 scopus 로고    scopus 로고
    • Topoisomerase II alpha gene status and prediction of pathological complete remission after anthrcycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neu-positie breast cancer
    • Orlando L, Del Curto B, Gandini S, et al. Topoisomerase II alpha gene status and prediction of pathological complete remission after anthrcycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neu-positie breast cancer. Breast 2008; 17:506-511.
    • (2008) Breast , vol.17 , pp. 506-511
    • Orlando, L.1    Del Curto, B.2    Gandini, S.3
  • 49
    • 62449154361 scopus 로고    scopus 로고
    • Role of anthracycline-based therapy in the adjuvant treatment of breast cancer: Efficacy analyses determined by molecular subtypes of the disease
    • [abstract]
    • Slamon DJ, Mackey J, Robert N, et al. Role of anthracycline-based therapy in the adjuvant treatment of breast cancer: efficacy analyses determined by molecular subtypes of the disease. San Antonio Breast Cancer Symposium 2007:13 [abstract].
    • (2007) San Antonio Breast Cancer Symposium , pp. 13
    • Slamon, D.J.1    Mackey, J.2    Robert, N.3
  • 50
    • 36849081991 scopus 로고    scopus 로고
    • HER-2, TOP2A and chromosome 17 alterations in breast cancer
    • Beser AR, Tuzlali S, Guzey D, et al. HER-2, TOP2A and chromosome 17 alterations in breast cancer. Pathol Oncol Res 2007; 13:180-185.
    • (2007) Pathol Oncol Res , vol.13 , pp. 180-185
    • Beser, A.R.1    Tuzlali, S.2    Guzey, D.3
  • 51
    • 0346125406 scopus 로고    scopus 로고
    • TOP2A and HER-2 gene amplification in fine needle aspirates from breast carcinomas
    • DOI 10.1046/j.0956-5507.2003.00088.x
    • Bofin AM, Ytterhus B, Hagmar BM. TOP2A and HER-2 gene amplification in fine needle aspirates from breast carcinomas. Cytopathology 2003; 14:314-319. (Pubitemid 37521861)
    • (2003) Cytopathology , vol.14 , Issue.6 , pp. 314-319
    • Bofin, A.M.1    Ytterhus, B.2    Hagmar, B.M.3
  • 53
    • 71749109002 scopus 로고    scopus 로고
    • High resolution representational oligonucleotide microarray analysis (ROMA) suggests that TOP02 and HER2 coamplification is uncommon in human breast cancer
    • [abstract]
    • McArthur HL, Tan LK, Patil S, et al. High resolution representational oligonucleotide microarray analysis (ROMA) suggests that TOP02 and HER2 coamplification is uncommon in human breast cancer. San Antonio Breast Cancer Symposium 2008:2023 [abstract].
    • (2008) San Antonio Breast Cancer Symposium , pp. 2023
    • McArthur, H.L.1    Tan, L.K.2    Patil, S.3
  • 54
    • 66849109884 scopus 로고    scopus 로고
    • Chromosome 17 polysomy (Ch17) as a predictor of anthraoycline response: Emerging evidence form the UK NEAT adjuvant breast cancer trial
    • [abstract]
    • Bartlett JMS, Munro A, Dunn JA, et al. Chromosome 17 polysomy (Ch17) as a predictor of anthraoycline response: emerging evidence form the UK NEAT adjuvant breast cancer trial. San Antonio Breast Cancer Symposium 2008:45 [abstract].
    • (2008) San Antonio Breast Cancer Symposium , pp. 45
    • Bartlett, J.M.S.1    Munro, A.2    Dunn, J.A.3
  • 55
    • 0033870292 scopus 로고    scopus 로고
    • Amplification and deletion of topoisomerase IIα associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
    • Järvinen TA, Tanner M, Rantanen V, et al. Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to the topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol 2000; 156:839-847. (Pubitemid 30626942)
    • (2000) American Journal of Pathology , vol.156 , Issue.3 , pp. 839-847
    • Jarvinen, T.A.H.1    Tanner, M.2    Rantanen, V.3    Barlund, M.4    Borg, A.5    Grenman, S.6    Isola, J.7
  • 56
    • 47949130625 scopus 로고    scopus 로고
    • Topoisomerase levels determine chemotherapy response in vitro and in vivo
    • Burgess D, Doles J, Zender L, et al. Topoisomerase levels determine chemotherapy response In vitro and In vivo. Proc Natl Acad Sci U S A 2008; 105:9053-9058.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9053-9058
    • Burgess, D.1    Doles, J.2    Zender, L.3
  • 59
    • 62849109983 scopus 로고    scopus 로고
    • Breast cancer and aneusomy 17: Implications for carcinogenesis and therapeutic response
    • Reinholz MM, Bruzek AK, Visscher DW. Breast cancer and aneusomy 17: implications for carcinogenesis and therapeutic response. Lancet Oncol 2009; 10:267-277.
    • (2009) Lancet Oncol , vol.10 , pp. 267-277
    • Reinholz, M.M.1    Bruzek, A.K.2    Visscher, D.W.3
  • 61
    • 48949119466 scopus 로고    scopus 로고
    • Inflammation and breast cancer: Metalloproteinases as common effectors of inflammation and extracellular matrix breakdown in breast cancer
    • Hojilla CV, Wood GA, Khokha R. Inflammation and breast cancer: metalloproteinases as common effectors of inflammation and extracellular matrix breakdown In breast cancer. Breast Cancer Res 2008; 10:205.
    • (2008) Breast Cancer Res , vol.10 , pp. 205
    • Hojilla, C.V.1    Wood, G.A.2    Khokha, R.3
  • 63
    • 34248331636 scopus 로고    scopus 로고
    • Elevated plasma tissue inhibitor of metalloproteinase-1 level predicts decreased response and survival in metastatic breast cancer
    • DOI 10.1002/cncr.22637
    • Lipton A, Ali SM, Leitzel K, et al. Elevated plasma tissue inhibitor of metalloproteinase-1 level predicts decreased response and survival in metastatic breast cancer. Cancer 2007; 109:1933-1939. (Pubitemid 46744185)
    • (2007) Cancer , vol.109 , Issue.10 , pp. 1933-1939
    • Lipton, A.1    Ali, S.M.2    Leitzel, K.3    Demers, L.4    Evans, D.B.5    Hamer, P.6    Brown-Shimer, S.7    Pierce, K.8    Carney, W.9
  • 64
    • 74549182134 scopus 로고    scopus 로고
    • Lack of TIMP-1 tumor cell immunoreactivity predicts effect of adjuvant anthraoycline based chemotherapy in patients (n 647) with primary breast cancer
    • [abstract]
    • Willemoe GL, Hertel PB, Bartels A, et al. Lack of TIMP-1 tumor cell immunoreactivity predicts effect of adjuvant anthraoycline based chemotherapy in patients (n 647) with primary breast cancer. San Antonio Breast Cancer Symposiom 2008:6042 [abstract].
    • (2008) San Antonio Breast Cancer Symposiom , pp. 6042
    • Willemoe, G.L.1    Hertel, P.B.2    Bartels, A.3
  • 67
    • 58149334773 scopus 로고    scopus 로고
    • A stroma-related gene signature predicts response to neoadjuvant chemotherapy in breast cancer
    • Farmer P, Bonnefoi H, Anderle P, et al. A stroma-related gene signature predicts response to neoadjuvant chemotherapy in breast cancer. Nat Med 2009; 1:68-74.
    • (2009) Nat Med , vol.1 , pp. 68-74
    • Farmer, P.1    Bonnefoi, H.2    Anderle, P.3


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