-
1
-
-
34548144717
-
Multiagent chemotherapy for early breast cancer
-
Early Breast Cancer Trialists' Collaborative Group
-
Early Breast Cancer Trialists' Collaborative Group: multiagent chemotherapy for early breast cancer. Cochrane Database Syst Rev 1 :CD000487, 2002.
-
(2002)
Cochrane Database Syst Rev
, vol.1
-
-
-
2
-
-
0003998061
-
-
8th ed. Philadelphia, PA: Lippincott Williams and Wilkins
-
DeVita V, Lawrence T, Rosenberg S. DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. 8th ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2008.
-
(2008)
Rosenberg's Cancer: Principles & Practice of Oncology.
-
-
DeVita, V.1
Lawrence, T.2
Rosenberg, S.3
DeVita, H.4
-
3
-
-
34547617889
-
BRCA1- And BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II
-
DOI 10.1158/0008-5472.CAN-07-0601
-
Treszezamsky AD, Kachnic LA, Feng Z, et al. BRCA1- and BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II. Cancer Res 2007; 67:7078-7081. (Pubitemid 47206532)
-
(2007)
Cancer Research
, vol.67
, Issue.15
, pp. 7078-7081
-
-
Treszezamsky, A.D.1
Kachnic, L.A.2
Feng, Z.3
Zhang, J.4
Tokadjian, C.5
Powell, S.N.6
-
4
-
-
62449090881
-
Guidelines for human epidermal growth factor receptor 2 testing: Biologic and methodologie considerations
-
Sauter G, Lee J, Bartlett J, et al. Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologie considerations. J Clin One 2009; 8:1323-1333.
-
(2009)
J Clin One
, vol.8
, pp. 1323-1333
-
-
Sauter, G.1
Lee, J.2
Bartlett, J.3
-
5
-
-
33847147313
-
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
-
DOI 10.1200/JCO.2006.09.2775
-
Wolff A, Hammond M, Schwartz, et al. American Society of Clinical Oncology/ College of American Pathologists Guideline Recommendations for Human Epidermal Growth Factor Receptor 2 Testing In Breast Cancer. J Clin One 2007; 1:118-145. (Pubitemid 350003059)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.1
, pp. 118-145
-
-
Wolff, A.C.1
Hammond, M.E.H.2
Schwartz, J.N.3
Hagerty, K.L.4
Allred, D.C.5
Cote, R.J.6
Dowsett, M.7
Fitzgibbons, P.L.8
Hanna, W.M.9
Langer, A.10
McShane, L.M.11
Paik, S.12
Pegram, M.D.13
Perez, E.A.14
Press, M.F.15
Rhodes, A.16
Sturgeon, C.17
Taube, S.E.18
Tubbs, R.19
Vance, G.H.20
Van De Vijver, M.21
Wheeler, T.M.22
Hayes, D.F.23
more..
-
6
-
-
33444464678
-
Focal HER2/neu amplified clones partially account for discordance between immunohistochemistry and fluorescence in-situ hybridization results: Data from NCCTG N9831 lntergroup Adjuvant Trial
-
[abstract]
-
Miller DV, Jenkins RB, Lingle WL, et al. Focal HER2/neu amplified clones partially account for discordance between immunohistochemistry and fluorescence in-situ hybridization results: data from NCCTG N9831 lntergroup Adjuvant Trial. Proc Am Soc Clin Oncol 2004; 568 [abstract].
-
(2004)
Proc Am Soc Clin Oncol
, pp. 568
-
-
Miller, D.V.1
Jenkins, R.B.2
Lingle, W.L.3
-
7
-
-
0032538040
-
ErbB-2 and response to doxorubicin in patients with axillary lymph node- Positive, hormone receptor-negative breast cancer
-
Paik S, Bryant J, Park C, et al. ErbB-2 and response to doxorubicin In patients with axillary lymph node-positive, hormone receptor-negative breast cancer. J Natl Cancer Inst 1998; 90:1361-1370. (Pubitemid 28439960)
-
(1998)
Journal of the National Cancer Institute
, vol.90
, Issue.18
, pp. 1361-1370
-
-
Paik, S.1
Bryant, J.2
Park, C.3
Fisher, B.4
Tan-Chiu, E.5
Hyams, D.6
Fisher, E.R.7
Lippman, M.E.8
Wickerham, D.L.9
Wolmark, N.10
-
8
-
-
0034694659
-
HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National surgical adjuvant breast and bowel project protocol B-15
-
Paik S, Bryant J, Tan-Chiu E, et al. HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-15. J Natl Cancer Inst 2000; 92:1991-1998. (Pubitemid 32045895)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.24
, pp. 1991-1998
-
-
Paik, S.1
Bryant, J.2
Tan-Chiu, E.3
Yothers, G.4
Park, C.5
Wickerham, D.L.6
Wolmark, N.7
-
9
-
-
0025063119
-
Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: Results from the National Surgical Adjuvant Breast and Bowel Project B-15
-
Fisher B, Brown AM, Dimitrov NV, et al. Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: results from the National Surgical Adjuvant Breast and Bowel Project B-15. J Clin Oncol 1990; 8:1483-1496.
-
(1990)
J Clin Oncol
, vol.8
, pp. 1483-1496
-
-
Fisher, B.1
Brown, A.M.2
Dimitrov, N.V.3
-
10
-
-
0003298825
-
HER2 expression and anthracycline effect: Results from the Naples GUN3 randomised trial
-
[abstract]
-
De Laurentiis M, Caputo F, Massarelli E, et al. HER2 expression and anthracycline effect: results from the Naples GUN3 randomised trial. Proc Am Soc Clin Oncol 2001 ; 133 [abstract].
-
(2001)
Proc Am Soc Clin Oncol
, pp. 133
-
-
De Laurentiis, M.1
Caputo, F.2
Massarelli, E.3
-
11
-
-
0036091354
-
HER-2 amplification and topoisomerase IIα gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
-
Di Leo A, Gancberg D, Larsimont D, et al. HER-2 amplification and topoisomerase II alpha gene aberrations as predictive markers In node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin Cancer Res 2002; 8:1107-1116. (Pubitemid 34517647)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.5
, pp. 1107-1116
-
-
Di Leo, A.1
Gancberg, D.2
Larsimont, D.3
Tanner, M.4
Jarvinen, T.5
Rouas, G.6
Dolci, S.7
Leroy, J.-Y.8
Paesmans, M.9
Isola, J.10
Piccart, M.J.11
-
12
-
-
0037317929
-
HER2 overexpression and doxorubicin in adjuvant chemotherapy for resectable breast cancer
-
DOI 10.1200/JCO.2003.04.021
-
Moliterni A, Menard S, Valagussa P, et al. HER2 overexpression and doxorubicin In adjuvant chemotherapy for resectable breast cancer. J Clin Oncol 2003; 21:458-462. (Pubitemid 46606475)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.3
, pp. 458-462
-
-
Moliterni, A.1
Menard, S.2
Valagussa, P.3
Biganzoli, E.4
Boracchi, P.5
Balsari, A.6
Casalini, P.7
Tomasic, G.8
Marubini, E.9
Pilotti, S.10
Bonadonna, G.11
-
13
-
-
32944475493
-
Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group
-
DOI 10.1200/JCO.2005.11.007
-
Knoop AS, Knudsen H, Balslev E, et al. Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers In primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil. J Clin Oncol 2005; 23:7483-7490. (Pubitemid 46291811)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.30
, pp. 7483-7490
-
-
Knoop, A.S.1
Knudsen, H.2
Balslev, E.3
Rasmussen, B.B.4
Overgaard, J.5
Nielsen, K.V.6
Schonau, A.7
Gunnarsdottir, K.8
Olsen, K.E.9
Mouridsen, H.10
Ejlertsen, B.11
-
14
-
-
32944459739
-
HER2 overexpression as a predictive marker in a randomized trial comparing adjuvant cyclophosphamide/methotrexate/5-fluorouracil with epirubicin in patients with stage I/II breast cancer: Long-term results
-
Colozza M, Sidoni A, Mosconi AM, et al. HER2 overexpression as a predictive marker In a randomized trial comparing adjuvant cyclophosphamide /methotrexate/5-fluorouracil with epirubicin In patients with stage I/II breast cancer: long-term results. Clin Breast Cancer 2005; 6:253-259. (Pubitemid 47050802)
-
(2005)
Clinical Breast Cancer
, vol.6
, Issue.3
, pp. 253-259
-
-
Colozza, M.1
Sidoni, A.2
Mosconi, A.M.3
Cavaliere, A.4
Bisagni, G.5
Gori, S.6
De Angelis, V.7
Frassoldati, A.8
Cherubini, R.9
Bian, A.R.10
Rodino, C.11
Mazzocchi, B.12
Mihailova, Z.13
Bucciarelli, E.14
Tonato, M.15
-
15
-
-
33646681444
-
HER2 and responsiveness of breast cancer to adjuvant chemotherapy
-
Pritchard KI, Shepherd LE, O'Malley FP, et al. HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med 2006; 354:2103-2111.
-
(2006)
N Engl J Med
, vol.354
, pp. 2103-2111
-
-
Pritchard, K.I.1
Shepherd, L.E.2
O'Malley, F.P.3
-
16
-
-
4243739866
-
C-erbB2 overexpression and treatment outcome in a randomized trial comparing adjuvant CMF and AC in equitoxic regiment in breast cancer
-
[abstract]
-
Petruzelka L, Pribylova O, Vedralova J, et al. C-erbB2 overexpression and treatment outcome In a randomized trial comparing adjuvant CMF and AC In equitoxic regiment In breast cancer. Proc Am Soc Clin Oncol 2000:534 [abstract].
-
(2000)
Proc Am Soc Clin Oncol
, pp. 534
-
-
Petruzelka, L.1
Pribylova, O.2
Vedralova, J.3
-
17
-
-
0000286972
-
HER2 overexpression as a predictor of survival in a trial comparing adjuvant FAC and CMF in breast cancer
-
[abstract]
-
Vera R, Albanell, Lirola JL, et al. HER2 overexpression as a predictor of survival In a trial comparing adjuvant FAC and CMF In breast cancer. Proc Am Soc Clin Oncol 1999:265 [abstract].
-
(1999)
Proc Am Soc Clin Oncol
, pp. 265
-
-
Vera, R.1
Albanell Lirola, J.L.2
-
18
-
-
65549158566
-
Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy
-
O'Malley F, Chia S, Tu D, et al. Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy. J Natl Cancer Inst 2009; 101:644650.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 644650
-
-
O'Malley, F.1
Chia, S.2
Tu, D.3
-
19
-
-
0032538050
-
ErbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer
-
Thor AD, Berry DA, Budman DR, et al. ErbB-2, p53, and efficacy of adjuvant therapy In lymph node-positive breast cancer. J Natl Cancer Inst 1998; 90:1346-1360.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1346-1360
-
-
Thor, A.D.1
Berry, D.A.2
Budman, D.R.3
-
20
-
-
33744969590
-
Topoisomerase IIα gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Cancer Group Trial 9401
-
Tanner M, Isola J, Wiklund T, et al. Topoisomerase IIα gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy In HER-2/neu-amplified breast cancer: Scandinavian Breast Cancer Group Trial 9401. J Clin Oncol 2006; 24:2428-2436.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2428-2436
-
-
Tanner, M.1
Isola, J.2
Wiklund, T.3
-
21
-
-
54849441046
-
Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trials
-
Bartlett JMS, Munro AF, Cameron DA, et al. Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines In the BR9601 adjuvant breast cancer chemotherapy trials. J Clin Oncol 2008; 26:5027-5035.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5027-5035
-
-
Bartlett, J.M.S.1
Munro, A.F.2
Cameron, D.A.3
-
22
-
-
38049181708
-
Anthracyclines in the treatment of HER2negative breast cancer. [Editorial]
-
Paik S, Taniyama Y, Geyer C. Anthracyclines In the treatment of HER2negative breast cancer. [Editorial]. J Natl Cancer Inst 2008; 100:6-8.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 6-8
-
-
Paik, S.1
Taniyama, Y.2
Geyer, C.3
-
23
-
-
43149115407
-
HER2/neu in systemic therapy for women with breast cancer: A systematic review
-
DOI 10.1007/s10549-007-9656-y
-
Dhesy-Thind B, Pritchard KI, Messersmith H, et al. Her-2/neu In systemic therapy for women with breast cancer: a systemic review. Breast Cancer Res Treat 2008; 109:209-229. (Pubitemid 351644854)
-
(2008)
Breast Cancer Research and Treatment
, vol.109
, Issue.2
, pp. 209-229
-
-
Dhesy-Thind, B.1
Pritchard, K.I.2
Messersmith, H.3
O'Malley, F.4
Elavathil, L.5
Trudeau, M.6
-
24
-
-
38049103907
-
HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: A pooled analysis of randomized trials
-
DOI 10.1093/jnci/djm252
-
Gennari A, Sormani MP, Pronzato P, et al. HER-2 status and efficacy of adjuvant anthracyclines in early breast cancer: a pooled analysis of randomized trials. J Natl Cancer Inst 2008; 100:14-20. (Pubitemid 351767337)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.1
, pp. 14-20
-
-
Gennari, A.1
Sormani, M.P.2
Pronzato, P.3
Puntoni, M.4
Colozza, M.5
Pfeffer, U.6
Bruzzi, P.7
-
25
-
-
33947317453
-
BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC→T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC→TH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients
-
[abstract]
-
Slamon D, Elermann W, Robert N, et al. BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC→T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC→TH) with docetaxel, carboplatin and trastuzumab (TCH) In Her2neu positive early breast cancer patients. San Antonio Breast Cancer Symposium 2006:52 [abstract].
-
(2006)
San Antonio Breast Cancer Symposium
, pp. 52
-
-
Slamon, D.1
Elermann, W.2
Robert, N.3
-
26
-
-
0034900175
-
Induction of topoisomerase II activity after ErbB2 activation is associated with a differential response to breast cancer chemotherapy
-
Harris LN, Yang L, Liotcheva V, et al. Induction of topoisomerase II activity after ErbB2 activation Is associated with a differential response to breast cancer chemotherapy. Clin Cancer Res 2001; 7:1497-1504. (Pubitemid 32708611)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.6
, pp. 1497-1504
-
-
Harris, L.N.1
Yang, L.2
Liotcheva, V.3
Pauli, S.4
Iglehart, J.D.5
Colvin, O.M.6
Tao Shih, H.7
-
27
-
-
41649102048
-
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
-
Liedtke C, Mazouni C, Hess KR, et al. Response to neoadjuvant therapy and long-term survival In patients with triple-negative breast cancer. J Clin One 2008; 26:1275-1281.
-
(2008)
J Clin One
, vol.26
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
-
28
-
-
33847063053
-
The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
-
DOI 10.1158/1078-0432.CCR-06-1109
-
Carey LA, Dees EC, Sawyer L, et al. The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Research 2007; 13:2329-2334. (Pubitemid 46698581)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.8
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
Gatti, L.4
Moore, D.T.5
Collichio, F.6
Ollila, D.W.7
Sartor, C.I.8
Graham, M.L.9
Perou, C.M.10
-
29
-
-
0032189276
-
Physiological regulation of eukaryotic topoisomerase II
-
Isaacs RJ, Davies SL, Sandi Ml, et al. Physiological regulation of eukaryotic topoisomerase II. Biochim Biophys Acta 1998; 1400:121-137.
-
(1998)
Biochim Biophys Acta
, vol.1400
, pp. 121-137
-
-
Isaacs, R.J.1
Davies, S.L.2
Ml, S.3
-
30
-
-
17744364850
-
Cell cycle-coupled variation in topoisomerase IIα mRNA is regulated by the 3′-untranslated region: Possible role of redox-sensitive protein binding in mRNA accumulation
-
DOI 10.1074/jbc.M005298200
-
Goswami PC, Sheren J, Albee LD, et al. Cell cycle-coupled variation in topoisomerase II alpha mRNA Is regulated by the 3'-untranslated region. Possible role of redox sensitive protein binding In mRNA accumulation. J Biol Chem 2000; 275:3384-3392. (Pubitemid 32009162)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.49
, pp. 38384-38392
-
-
Goswami, P.C.1
Sheren, J.2
Albee, L.D.3
Parsian, A.4
Sim, J.E.5
Ridnour, L.A.6
Higashikubo, R.7
Gius, D.8
Hunt, C.R.9
Spitz, D.R.10
-
31
-
-
16644362006
-
Correlation between topoisomerase-II alpha gene amplification and protein expression in HER-2 amplified breast cancer
-
Durbecq V, Desmedt C, Paesmans M, et al. Correlation between topoisomerase-II alpha gene amplification and protein expression in HER-2 amplified breast cancer. Int J Oncol 2004; 25:1473-1479.
-
(2004)
Int J Oncol
, vol.25
, pp. 1473-1479
-
-
Durbecq, V.1
Desmedt, C.2
Paesmans, M.3
-
32
-
-
1542343905
-
Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein In human breast tumor samples
-
DOI 10.1002/gcc.20008
-
Mueller RE, Parkes RK, Andrulis I, O'Malley FP. Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein In human breast tumor samples. Genes Chromosomes Cancer 2004; 39:288-297. (Pubitemid 38326310)
-
(2004)
Genes Chromosomes and Cancer
, vol.39
, Issue.4
, pp. 288-297
-
-
Mueller, R.E.1
Parkes, R.K.2
Andrulis, I.3
O'Malley, F.P.4
-
33
-
-
13844281018
-
Identification and validation of prognostic markers in breast cancer with the complementary use of array-CGH and tissue microarrays
-
DOI 10.1002/path.1694
-
Callagy G, Pharoah P, Chin SF, et al. Identification and validation of prognostic markers In breast cancer with complementary use of array-CGH and tissue microarrays. J Pathol 2005; 205:388-396. (Pubitemid 40253928)
-
(2005)
Journal of Pathology
, vol.205
, Issue.3
, pp. 388-396
-
-
Callagy, G.1
Pharoah, P.2
Chin, S.-F.3
Sangan, T.4
Daigo, Y.5
Jackson, L.6
Caldas, C.7
-
34
-
-
0031775808
-
Predictive value of topoisomerase IIα and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
-
Jarvinen TA, Holli K, Kuukasjarvi T, Isola JJ. Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy In advanced breast cancer. Br J Cancer 1998; 77:2267-2273. (Pubitemid 28263952)
-
(1998)
British Journal of Cancer
, vol.77
, Issue.12
, pp. 2267-2273
-
-
Jarvinen, T.A.H.1
Holli, K.2
Kuukasjarvi, T.3
Isola, J.J.4
-
35
-
-
0029665095
-
Expression of topoisomerase IIα is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer
-
Jarvinen TA, Kononen J, Pelto-Huikko M, Isola J. Expression of topoisomerase II alpha Is associated with rapid cell proliferation, aneuploidy, and c-erbB2 over expression In breast cancer. Am J Pathol 1996; 148:2073-2082. (Pubitemid 26170530)
-
(1996)
American Journal of Pathology
, vol.148
, Issue.6
, pp. 2073-2082
-
-
Jarvinen, T.A.H.1
Kononen, J.2
Pelto-Huikko, M.3
Isola, J.4
-
36
-
-
0034486459
-
DNA topoisomerase II-alpha immunoreactivity as a marker of tumor aggressiveness in invasive breast cancer
-
DOI 10.1159/000055914
-
Nakopoulou L, Lazaris AC, Kavantzas N, et al. DNA topoisomerase II-alpha immunoreactivity as a marker of tumor aggressiveness in invasive breast cancer. Pathobiology 2000; 68:137-143. (Pubitemid 32110322)
-
(2000)
Pathobiology
, vol.68
, Issue.3
, pp. 137-143
-
-
Nakopoulou, L.1
Lazaris, A.C.2
Kavantzas, N.3
Alexandrou, P.4
Athanassiadou, P.5
Keramopoulos, A.6
Davaris, P.7
-
37
-
-
55549097827
-
Anthracyclines: The first generation of cytotoxic targeted agents? A possible dream
-
Di Leo A, Moretti E. Anthracyclines: the first generation of cytotoxic targeted agents? A possible dream. j Clin Oncol 2008; 31:5027-5035.
-
(2008)
J Clin Oncol
, vol.31
, pp. 5027-5035
-
-
Di Leo, A.1
Moretti, E.2
-
38
-
-
70249085601
-
Topoisomerase IIα amplification does not predict benefit from dose-intense cyclophosphamide, doxorubicin, and fluorouracil therapy in HER2-amplified early breast cancer: Results of CALGB 8541/150013
-
Harris LN, Broadwater G, Abu-Khalaf M, et al. Topoisomerase IIα amplification does not predict benefit from dose-intense cyclophosphamide, doxorubicin, and fluorouracil therapy In HER2-amplified early breast cancer: Results of CALGB 8541/150013. J Clin Oncol 2009; 21:3430-3436.
-
(2009)
J Clin Oncol
, vol.21
, pp. 3430-3436
-
-
Harris, L.N.1
Broadwater, G.2
Abu-Khalaf, M.3
-
39
-
-
76649103646
-
A meta-analysis of phase III trials evaluating the predictive value of HER2 and topoisomerase II alpha in early breast cancer patients treated with CMF or anthracycline-based adjuvant therapy
-
[abstract].
-
Di Leo A, Isola J, Piette F, et al. A meta-analysis of phase III trials evaluating the predictive value of HER2 and topoisomerase II alpha in early breast cancer patients treated with CMF or anthracycline-based adjuvant therapy. San Antonio Breast Cancer Symposium 2008:705 [abstract].
-
(2008)
San Antonio Breast Cancer Symposium
, pp. 705
-
-
Di Leo, A.1
Isola, J.2
Piette, F.3
-
40
-
-
0030626492
-
Heterogeneous expression of DNA topoisomerase II alpha isoforms in tumor cell lines
-
Mo YY, Beck WT. Heterogeneous expression of DNA topoisomerase II alpha isoforms in tumor cell lines. Oncol Res 1997; 9:193-204.
-
(1997)
Oncol Res
, vol.9
, pp. 193-204
-
-
Mo, Y.Y.1
Beck, W.T.2
-
42
-
-
4344627104
-
Human topoisomerase IIα nuclear export is mediated by two CRM-1-dependent nuclear export signals
-
DOI 10.1242/jcs.01147
-
Turner JG, Engel R, Derderian JA, et al. Human topoisomerase II alpha nuclear export Is mediated by two CRM-1 -dependent nuclear export signals. J Cell Sci 2004; 117:3061-3071. (Pubitemid 39117680)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.14
, pp. 3061-3071
-
-
Turner, J.G.1
Engel, R.2
Derderian, J.A.3
Jove, R.4
Sullivan, D.M.5
-
43
-
-
0034667463
-
Changes in subcellular distribution of topoisomerase IIα correlate with etoposide resistance in multicell spheroids and xenograft tumors
-
Oloumi A, MacPhail SH, Johnston PJ, et al. Changes in subcellular distribution of topoisomerase II alpha correlate with etoposide resistance in multicell spheroid and xenograft tumours. Cancer Res 2000; 60:5747-5753. (Pubitemid 30808310)
-
(2000)
Cancer Research
, vol.60
, Issue.20
, pp. 5747-5753
-
-
Oloumi, A.1
MacPhail, S.H.2
Johnston, P.J.3
Banath, J.P.4
Olive, P.L.5
-
44
-
-
0033865826
-
Ectopic expression of human topoisomerase II alpha fragments and etoposide resistance in mammalian cells
-
Ernst Al, Soltermann A, Sigrist JA, et al. Ectopic expression of human topoisomerase II alpha fragments and etoposide resistance in mammalian cells. Int J Cancer 2000; 88:99-107.
-
(2000)
Int J Cancer
, vol.88
, pp. 99-107
-
-
Al, E.1
Soltermann, A.2
Sigrist, J.A.3
-
46
-
-
55549143664
-
AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma
-
Gustavson MD, Molinaro AM, Tedesch G, et al. AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma. Arch Pathol Lab Med 2008; 132:17461752.
-
(2008)
Arch Pathol Lab Med
, vol.132
, pp. 17461752
-
-
Gustavson, M.D.1
Molinaro, A.M.2
Tedesch, G.3
-
47
-
-
70449716281
-
Predicting the efficacy of anthracyclines in breast cancer (BC) patients: Results of the neoadjuvant TOP trial
-
[abstract]
-
Desmedt C, Azambuja E, Larsimont D, et al. Predicting the efficacy of anthracyclines In breast cancer (BC) patients: Results of the neoadjuvant TOP trial. Proc Am Soc Clin Oncol 2009:523 [abstract].
-
(2009)
Proc Am Soc Clin Oncol
, pp. 523
-
-
Desmedt, C.1
Azambuja, E.2
Larsimont, D.3
-
48
-
-
53149089444
-
Topoisomerase II alpha gene status and prediction of pathological complete remission after anthrcycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neu-positie breast cancer
-
Orlando L, Del Curto B, Gandini S, et al. Topoisomerase II alpha gene status and prediction of pathological complete remission after anthrcycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neu-positie breast cancer. Breast 2008; 17:506-511.
-
(2008)
Breast
, vol.17
, pp. 506-511
-
-
Orlando, L.1
Del Curto, B.2
Gandini, S.3
-
49
-
-
62449154361
-
Role of anthracycline-based therapy in the adjuvant treatment of breast cancer: Efficacy analyses determined by molecular subtypes of the disease
-
[abstract]
-
Slamon DJ, Mackey J, Robert N, et al. Role of anthracycline-based therapy in the adjuvant treatment of breast cancer: efficacy analyses determined by molecular subtypes of the disease. San Antonio Breast Cancer Symposium 2007:13 [abstract].
-
(2007)
San Antonio Breast Cancer Symposium
, pp. 13
-
-
Slamon, D.J.1
Mackey, J.2
Robert, N.3
-
50
-
-
36849081991
-
HER-2, TOP2A and chromosome 17 alterations in breast cancer
-
Beser AR, Tuzlali S, Guzey D, et al. HER-2, TOP2A and chromosome 17 alterations in breast cancer. Pathol Oncol Res 2007; 13:180-185.
-
(2007)
Pathol Oncol Res
, vol.13
, pp. 180-185
-
-
Beser, A.R.1
Tuzlali, S.2
Guzey, D.3
-
51
-
-
0346125406
-
TOP2A and HER-2 gene amplification in fine needle aspirates from breast carcinomas
-
DOI 10.1046/j.0956-5507.2003.00088.x
-
Bofin AM, Ytterhus B, Hagmar BM. TOP2A and HER-2 gene amplification in fine needle aspirates from breast carcinomas. Cytopathology 2003; 14:314-319. (Pubitemid 37521861)
-
(2003)
Cytopathology
, vol.14
, Issue.6
, pp. 314-319
-
-
Bofin, A.M.1
Ytterhus, B.2
Hagmar, B.M.3
-
53
-
-
71749109002
-
High resolution representational oligonucleotide microarray analysis (ROMA) suggests that TOP02 and HER2 coamplification is uncommon in human breast cancer
-
[abstract]
-
McArthur HL, Tan LK, Patil S, et al. High resolution representational oligonucleotide microarray analysis (ROMA) suggests that TOP02 and HER2 coamplification is uncommon in human breast cancer. San Antonio Breast Cancer Symposium 2008:2023 [abstract].
-
(2008)
San Antonio Breast Cancer Symposium
, pp. 2023
-
-
McArthur, H.L.1
Tan, L.K.2
Patil, S.3
-
54
-
-
66849109884
-
Chromosome 17 polysomy (Ch17) as a predictor of anthraoycline response: Emerging evidence form the UK NEAT adjuvant breast cancer trial
-
[abstract]
-
Bartlett JMS, Munro A, Dunn JA, et al. Chromosome 17 polysomy (Ch17) as a predictor of anthraoycline response: emerging evidence form the UK NEAT adjuvant breast cancer trial. San Antonio Breast Cancer Symposium 2008:45 [abstract].
-
(2008)
San Antonio Breast Cancer Symposium
, pp. 45
-
-
Bartlett, J.M.S.1
Munro, A.2
Dunn, J.A.3
-
55
-
-
0033870292
-
Amplification and deletion of topoisomerase IIα associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
-
Järvinen TA, Tanner M, Rantanen V, et al. Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to the topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol 2000; 156:839-847. (Pubitemid 30626942)
-
(2000)
American Journal of Pathology
, vol.156
, Issue.3
, pp. 839-847
-
-
Jarvinen, T.A.H.1
Tanner, M.2
Rantanen, V.3
Barlund, M.4
Borg, A.5
Grenman, S.6
Isola, J.7
-
56
-
-
47949130625
-
Topoisomerase levels determine chemotherapy response in vitro and in vivo
-
Burgess D, Doles J, Zender L, et al. Topoisomerase levels determine chemotherapy response In vitro and In vivo. Proc Natl Acad Sci U S A 2008; 105:9053-9058.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9053-9058
-
-
Burgess, D.1
Doles, J.2
Zender, L.3
-
57
-
-
33750727368
-
Genomic signatures to guide the use of chemotherapeutics
-
DOI 10.1038/nm1491, PII NM1491
-
Potti A, Dressman H, Bild A, et al. Genomic signatures to guide the use of chemotherapeutics. Nat Med 2006; 12:1294-1300. (Pubitemid 44706932)
-
(2006)
Nature Medicine
, vol.12
, Issue.11
, pp. 1294-1300
-
-
Potti, A.1
Dressman, H.K.2
Bild, A.3
Riedel, R.F.4
Chan, G.5
Sayer, R.6
Cragun, J.7
Cottrill, H.8
Kelley, M.J.9
Petersen, R.10
Harpole, D.11
Marks, J.12
Berchuck, A.13
Ginsburg, G.S.14
Febbo, P.15
Lancaster, J.16
Nevins, J.R.17
-
58
-
-
36549068221
-
Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: A substudy of the EORTC 10994/BIG 00-01 clinical trial
-
DOI 10.1016/S1470-2045(07)70345-5, PII S1470204507703455
-
Bonnefoi H, Potti A, Delorenzi M, et al. Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial. Lancet Oncol 2007; 8:1071-1078. (Pubitemid 350182953)
-
(2007)
Lancet Oncology
, vol.8
, Issue.12
, pp. 1071-1078
-
-
Bonnefoi, H.1
Potti, A.2
Delorenzi, M.3
Mauriac, L.4
Campone, M.5
Tubiana-Hulin, M.6
Petit, T.7
Rouanet, P.8
Jassem, J.9
Blot, E.10
Becette, V.11
Farmer, P.12
Andre, S.13
Acharya, C.R.14
Mukherjee, S.15
Cameron, D.16
Bergh, J.17
Nevins, J.R.18
Iggo, R.D.19
-
59
-
-
62849109983
-
Breast cancer and aneusomy 17: Implications for carcinogenesis and therapeutic response
-
Reinholz MM, Bruzek AK, Visscher DW. Breast cancer and aneusomy 17: implications for carcinogenesis and therapeutic response. Lancet Oncol 2009; 10:267-277.
-
(2009)
Lancet Oncol
, vol.10
, pp. 267-277
-
-
Reinholz, M.M.1
Bruzek, A.K.2
Visscher, D.W.3
-
60
-
-
42549111727
-
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines
-
DOI 10.1038/labinvest.2008.19, PII LABINVEST200819
-
Arriola E, Marchio C, Tan D, et al. Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines. Lab Invest 2008; 88:491-503. (Pubitemid 351581454)
-
(2008)
Laboratory Investigation
, vol.88
, Issue.5
, pp. 491-503
-
-
Arriola, E.1
Marchio, C.2
Tan, D.S.P.3
Drury, S.C.4
Lambros, M.B.5
Natrajan, R.6
Rodriguez-Pinilla, S.M.7
Mackay, A.8
Tamber, N.9
Fenwick, K.10
Jones, C.11
Dowsett, M.12
Ashworth, A.13
Reis-Filho, J.S.14
-
61
-
-
48949119466
-
Inflammation and breast cancer: Metalloproteinases as common effectors of inflammation and extracellular matrix breakdown in breast cancer
-
Hojilla CV, Wood GA, Khokha R. Inflammation and breast cancer: metalloproteinases as common effectors of inflammation and extracellular matrix breakdown In breast cancer. Breast Cancer Res 2008; 10:205.
-
(2008)
Breast Cancer Res
, vol.10
, pp. 205
-
-
Hojilla, C.V.1
Wood, G.A.2
Khokha, R.3
-
62
-
-
34948837832
-
Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse
-
DOI 10.1038/sj.bjc.6603963, PII 6603963
-
González LO, Pidal I, Junquera S, et al. Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse. Br J Cancer 2007; 97:957-963. (Pubitemid 47519308)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.7
, pp. 957-963
-
-
Gonzalez, L.O.1
Pidal, I.2
Junquera, S.3
Corte, M.D.4
Vazquez, J.5
Rodriguez, J.C.6
Lamelas, M.L.7
Merino, A.M.8
Garcia-Muiz, J.L.9
Vizoso, F.J.10
-
63
-
-
34248331636
-
Elevated plasma tissue inhibitor of metalloproteinase-1 level predicts decreased response and survival in metastatic breast cancer
-
DOI 10.1002/cncr.22637
-
Lipton A, Ali SM, Leitzel K, et al. Elevated plasma tissue inhibitor of metalloproteinase-1 level predicts decreased response and survival in metastatic breast cancer. Cancer 2007; 109:1933-1939. (Pubitemid 46744185)
-
(2007)
Cancer
, vol.109
, Issue.10
, pp. 1933-1939
-
-
Lipton, A.1
Ali, S.M.2
Leitzel, K.3
Demers, L.4
Evans, D.B.5
Hamer, P.6
Brown-Shimer, S.7
Pierce, K.8
Carney, W.9
-
64
-
-
74549182134
-
Lack of TIMP-1 tumor cell immunoreactivity predicts effect of adjuvant anthraoycline based chemotherapy in patients (n 647) with primary breast cancer
-
[abstract]
-
Willemoe GL, Hertel PB, Bartels A, et al. Lack of TIMP-1 tumor cell immunoreactivity predicts effect of adjuvant anthraoycline based chemotherapy in patients (n 647) with primary breast cancer. San Antonio Breast Cancer Symposiom 2008:6042 [abstract].
-
(2008)
San Antonio Breast Cancer Symposiom
, pp. 6042
-
-
Willemoe, G.L.1
Hertel, P.B.2
Bartels, A.3
-
66
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
DOI 10.1038/nm1764, PII NM1764
-
Finak G, Bertos N, Pepin F, et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med 2008; 14:518-527. (Pubitemid 351655218)
-
(2008)
Nature Medicine
, vol.14
, Issue.5
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
Sadekova, S.4
Souleimanova, M.5
Zhao, H.6
Chen, H.7
Omeroglu, G.8
Meterissian, S.9
Omeroglu, A.10
Hallett, M.11
Park, M.12
-
67
-
-
58149334773
-
A stroma-related gene signature predicts response to neoadjuvant chemotherapy in breast cancer
-
Farmer P, Bonnefoi H, Anderle P, et al. A stroma-related gene signature predicts response to neoadjuvant chemotherapy in breast cancer. Nat Med 2009; 1:68-74.
-
(2009)
Nat Med
, vol.1
, pp. 68-74
-
-
Farmer, P.1
Bonnefoi, H.2
Anderle, P.3
|