Insufficient evidence to suggest less stringent therapy in hemophilia B?

Blood

Volumn 114, Issue 23, 2009, Pages 4907-

  Den Uijl, Ingrid E M ^a   Roosendaal, Goris ^a   Fischer, Kathelijn ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTHROPLASTY; DISEASE SEVERITY; HEMOPHILIA A; HEMOPHILIA B; HOSPITALIZATION; HUMAN; LETTER; PRIORITY JOURNAL; PROPHYLAXIS; ADOLESCENT; ADULT; BLEEDING; CHILD; COHORT ANALYSIS; COMPARATIVE STUDY; FEMALE; HEMARTHROSIS; INFANT; ITALY; MALE; MIDDLE AGED; NETHERLANDS; NOTE; ONSET AGE; PHENOTYPE; PRESCHOOL CHILD; SAMPLE SIZE; STATISTICS; UTILIZATION REVIEW;

BLOOD CLOTTING FACTOR;

ADOLESCENT; ADULT; AGE OF ONSET; ARTHROPLASTY; BLOOD COAGULATION FACTORS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; HEMARTHROSIS; HEMOPHILIA A; HEMOPHILIA B; HEMORRHAGE; HOSPITALIZATION; HUMANS; INFANT; ITALY; MALE; MIDDLE AGED; NETHERLANDS; PHENOTYPE; SAMPLE SIZE; YOUNG ADULT;

EID: 74049108940     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-08-241240     Document Type: Letter

References (4)

1. Tagariello G, Iorio A, Santagostino E, et al. Comparison of the rates of joint arthroplasty in patients with severe factor VIII and IX deficiency: an index of different clinical severity of the 2 coagulation disorders. Blood. 2009;114(4):779-784.
2. Makris M. Is VIII worse than IX? Blood. 2009;114(4):750-751.
3. van Dijk K, Fischer K, van der Bom JG, Grobbee DE, van den Berg HM. Variability in clinical phenotype of severe haemophilia: the role of the first joint bleed. Haemophilia. 2005;11(5):438-443.
4. Lowe GD, Ludlam CA. Less severe bleeding in hemophilia B than in hemophilia A. J Thromb Haemost. 2008;6(11):1982-1983.