A combinational supercritical CO2 system for nanoparticle preparation of indomethacin

International Journal of Pharmaceutics

Volumn 386, Issue 1-2, 2010, Pages 243-248

  Tozuka, Yuichi ^a   Miyazaki, Yuta ^a   Takeuchi, Hirofumi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Indomethacin; Nanocrystal; Supercritical carbon dioxide

Indexed keywords

ALCOHOL; CARBON DIOXIDE; INDOMETACIN; NANOPARTICLE; NONSTEROID ANTIINFLAMMATORY AGENT; WATER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG SOLUBILITY; FREEZE DRYING; LIGHT SCATTERING; NANOPHARMACEUTICS; PARTICLE SIZE; PRECIPITATION; PRIORITY JOURNAL; SUPERCRITICAL FLUID; SUSPENSION; CHEMISTRY; CRYSTALLIZATION; KINETICS; NANOTECHNOLOGY; PHARMACEUTICS; POWDER; PRESSURE; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; SUPERCRITICAL FLUID CHROMATOGRAPHY; TEMPERATURE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARBON DIOXIDE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, SUPERCRITICAL FLUID; CRYSTALLIZATION; ETHANOL; FREEZE DRYING; INDOMETHACIN; KINETICS; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; NANOTECHNOLOGY; POWDERS; PRESSURE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; WATER;

EID: 74049100901     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.10.044     Document Type: Article

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