Lactate: An unusually sensitive parameter of ensuing organ failure?

Critical Care Medicine

Volumn 38, Issue 1, 2010, Pages 337-

  Van Beest, Paul ^a   Kuiper, Michael ^b   Spronk, Peter E ^c  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b MEDICAL CENTER LEEUWARDEN   (Netherlands)

^c GELRE HOSPITALS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HYPERTENSIVE FACTOR; LACTIC ACID; INOTROPIC AGENT; BIOLOGICAL MARKER;

HYPERLACTATEMIA; INTENSIVE CARE UNIT; LACTATE BLOOD LEVEL; LENGTH OF STAY; LETTER; MULTIPLE ORGAN FAILURE; PRIORITY JOURNAL; PROGNOSIS; CRITICALLY ILL PATIENT; BLOOD; CAUSE OF DEATH; CRITICAL ILLNESS; FEMALE; HUMAN; INTENSIVE CARE; MALE; METHODOLOGY; MORTALITY; NOTE; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE;

BIOLOGICAL MARKERS; CAUSE OF DEATH; CRITICAL ILLNESS; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE; INTENSIVE CARE UNITS; LACTIC ACID; MALE; MULTIPLE ORGAN FAILURE; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE;

EID: 74049099362     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181bc7a88     Document Type: Letter

References (8)

1. Jansen T, van Bommel J, Woodward R, et al: Association between blood lactate levels, Sequential Organ Failure Assessment subscores, and 28-day mortality during early and late intensive care unit stay: A retrospective observational study. Crit Care Med 2009; 37: 2369-2374
2. Bakker J, Gris P, Coffernils M, et al: Serial blood lactate levels can predict the development of multiple organ failure following septic shock. Am J Surg 1996; 171:221-226
3. Nguyen HB, Rivers EP, Knoblich BP, et al: Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med 2004; 32:1637-1642
4. James JH, Luchette FA, Mccarter FD, et al: Lac-tate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet 1999; 354:505-508
5. Gladden LB: Lactate metabolism: A new paradigm for the third millenium. J Physiol 2004; 558:5-30
6. Blow O, Magliore L, Claridge JA, et al: The golden hour and the silver day: Detection and correction of occult hypoperfusion within 24h improves outcome from major trauma. J Trauma 1999; 47:964-969
7. Bernardin G, Pradier C, Tiger F, et al: Blood pressure and arterial lactate level are early indicators of short-term survival in human septic shock. Intensive Care Med 1996; 22:17-25
8. Rivers E, Nguyen B, Havstad S, et al; for the Early Goal-Directed Therapy Collaborative Group: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-1377