Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 1194-1197

  Guo, Lilu ^a,c   Suarez, Alirica I ^b   Braden, Michael R ^a   Gerdes, John M ^a   Thompson, Charles M ^a,c  

^a UNIVERSITY OF MONTANA   (United States)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^c ATERIS Technologies LLC   (United States)

Author keywords

Acetylcholinesterase; Chromophore; Fluorophosphonate; Inhibition; Modeling

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; FLUOROPHOSPHONATE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ARACHIDONIC ACID DERIVATIVE; GLYCOFUROL; MACROGOL DERIVATIVE; METHYL ARACHIDONYLFLUOROPHOSPHONATE;

ARTICLE; CHEMICAL STRUCTURE; CHROMATOPHORE; ENZYME ACTIVITY; GEL PERMEATION CHROMATOGRAPHY; MOLECULAR MODEL; PROTEIN STRUCTURE; SPECTROSCOPY; SYNTHESIS; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; METABOLISM; MOUSE;

ELECTROPHORUS ELECTRICUS;

ACETYLCHOLINESTERASE; ANIMALS; ARACHIDONIC ACIDS; CHOLINESTERASE INHIBITORS; MICE; ORGANOPHOSPHONATES; POLYETHYLENE GLYCOLS;

EID: 74049098327     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.007     Document Type: Article

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