Acetylcholinesterase activity in the brain of alloxan diabetic albino rats: Presence of an inhibitor of this enzyme activity in the cerebral extract

International Journal of Diabetes in Developing Countries

Volumn 29, Issue 4, 2009, Pages 174-177

  Ahmed, Nayeemunnisa ^a   Tarannum, Suraiya ^b  

^a AL AMEEN COLLEGE OF PHARMACY   (India)

^b AMC ENGINEERING COLLEGE   (India)

Author keywords

AChE; Alloxan diabetes; Brain; Cerebral extract; Cichorium intybus (Chicory); Inhibitor

Indexed keywords

EID: 74049094110     PISSN: 09733930     EISSN: 19983832     Source Type: Journal    
DOI: 10.4103/0973-3930.57350     Document Type: Article

References (11)

1. Green DA, Latt imer SA. Vascular and metabolic factors in the pathogenesis of experimental diabetic neuropathy in mature rats. Diabetes Met Rev 1988;4:201-221
2. Green Tack DA, Takeuchi PR. Nerve microenvironment diabetic neuropathy, Neurochem 1994;117:1395-1407
3. Sukhwinder LS, Sharma P, Kaur G, Kaur G. Changes in glucose metabolism from discrete regions of rat brain and its relationship to reproductive failure during experimental diabetes. Mol Cell Biochem 1994;141:97-102.
4. Sen KS. Oxygen toxicity and antioxidants: State of the art. Indian J Physiol Pharmacol 1995;39:179-196
5. Galanopoulas E, Lellos V, Papakdis M, Phillippids H. Palailogos, effects of fasting and diabetes on some enzyme and transport of glutamate in the cortex slices or synaptosomes form brain. Neurochem Res 1988;13:243-248
6. Biessels GJ, Kappelle AC, Bravenboer B, Erkelens DW, Gispen WH. Cerebral function in diabetes mellitus. Diabetologia 1994;34:643-650
7. Ghareeb DA, Hussen HM, Vanadium improves brain acetylcholinesterase activity in early stage alloxan-diabetic rats. Neurosci Lett 2008;:436-447
8. Ashokkumar N, Pari L, Ramkumar KM, N-Benzoyl-Dphenylalanine attenuates acetylcholinesterase in neonatal steptozotocin-diabetic rats. Basic Clin Pharmacol Toxicol 2006;99:246-250
9. Nayeemunnisa, Nawaz R, Jayashree C. Changes in the original protein metabolism in the central nervous system (CNS) of diabetic rat: Protection by Cichorium intybus (Chicory). Phcogmag 2006;2:130-132
10. Nayeemunnisa, Kumada RM. Cardioprotective effects of Cichorium intybus in ageing myocardium of albino rats. Curr Sci 2003;84:941-943
11. Hestrin S. The reaction of acetylcholine and other carboxylic acid derivative with hydroxylamine and its analytical application. J Biol Chem 1949;180:249-261