N,N′-Dioxide-scandium(III) complex catalyzed highly enantioselective Friedel-Crafts alkylation of indole to alkylidene malonates

Tetrahedron

Volumn 66, Issue 7, 2010, Pages 1447-1457

  Liu, Yanling ^a   Zhou, Xin ^a   Shang, Deju ^a   Liu, Xiaohua ^a   Feng, Xiaoming ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Alkylidene malonates; Friedel crafts alkylation; Indole derivatives; N,N Dioxide scandium(III)

Indexed keywords

ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (2 CHLOROPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (2 NAPHTHLY)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (2 THIENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3 BROMOPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3 CHLOROPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3 METHOXYLPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3 METHYLPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3 NITROPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3 PHENOXYLPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3 TRIFLUOROMETHYLPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (3,4 DICHLOROPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 BROMOPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 CHLOROPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 CYANOPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 FLUORO 3 PHENOXYPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 FLUOROPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 METHYLPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 NITROPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (4 TRIFLUOROMETHYLPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 (CYCLOHEXYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 (3 INDOLYL) 3 PHENYLPROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 [3 (4 METHOXYINDOLYL)] 3 PHENYLPROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 [3 (5 BROMOINDOLYL)] 3 (3 BROMOPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 [3 (5 BROMOINDOLYL)] 3 PHENYLPROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 [3 (5 METHOXYINDOLYL)] 3 (4 PHENYLPHENYL)PROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 [3 (5 METHOXYINDOLYL)] 3 PHENYLPROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 [3 (6 METHOXYINDOLYL)] 3 PHENYLPROPANOATE; ETHYL 2 ETHOXYCARBONYL 3 [3 (7 METHYLINDOLYL)] 3 PHENYLPROPANOATE; INDOLE DERIVATIVE; MALONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL STRUCTURE; CHIRALITY; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENANTIOSELECTIVITY; FRIEDEL CRAFTS REACTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLVENT EFFECT; TEMPERATURE SENSITIVITY;

EID: 74049088104     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2009.12.032     Document Type: Article

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