Telomerase downregulation in cancer brain stem cell

Molecular and Cellular Biochemistry

Volumn 331, Issue 1-2, 2009, Pages 153-159

  Shervington, Amal ^a   Lu, Chen ^a   Patel, Rahima ^a   Shervington, Leroy ^a  

^a UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

Author keywords

Cancer stem cells; Cd133; hTERT; Serum deprivation

Indexed keywords

CD133 ANTIGEN; CELL MARKER; TELOMERASE; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; MESSENGER RNA; PEPTIDE;

ARTICLE; BRAIN CANCER; CANCER STEM CELL; CELL ISOLATION; CELL SELECTION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLIOMA CELL; HUMAN; HUMAN CELL; TRANSCRIPTION REGULATION; UPREGULATION; CULTURE MEDIUM; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANTIGENS, CD; CELL LINE, TUMOR; CULTURE MEDIA, SERUM-FREE; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; GLYCOPROTEINS; HUMANS; NEOPLASTIC STEM CELLS; PEPTIDES; RNA, MESSENGER; TELOMERASE;

EID: 74049087201     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-009-0153-y     Document Type: Article

References (32)

1. Hirschmann-Jax C, Foster AE, Wulf GG et al (2004) A distinct 'side population' of cells with high drug efflux capacity in human tumour cells. Proc Natl Acad Sci USA 101:14226-14233. doi:10.1073/pnas.0400067101 (Pubitemid 39305058)
2. Kondo T, Setoguchi T, Taga T (2004) Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci USA 101:781-786. doi:10.1073/pnas.0307618100 (Pubitemid 38121035)
3. Al-Hajj M, Wicha MS, Benito-Hernandez A et al (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100:3983-3988. doi:10.1073/pnas.0530291100 (Pubitemid 36418143)
4. Yuan X, Curtin J, Xiong Y et al (2004) Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23:9392-9400. doi:10.1038/sj.onc. 1208311 (Pubitemid 40069671)
5. Singh SK, Clarke ID, Terasaki M et al (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63:5821-5828
6. Singh SK, Hawkins C, Clarke ID et al (2004) Identification of human brain tumour initiating cells. Nature 432:396-401. doi:10.1038/nature03128 (Pubitemid 39551674)
7. Richardson GD, Robson CN, Lang SH et al (2004) CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci 117:3539-3545. doi:10.1242/jcs.01222 (Pubitemid 39206394)
8. Yu S, Zhang J, Zhao CL et al (2004) Isolation and characterization of the CD133+ precursors from the ventricular zone of human fetal brain by magnetic affinity cell sorting. Biotechnol Lett 26:1131-1136. doi:10.1023/B:BILE. 0000035484.64499.ac (Pubitemid 39048068)
9. Amit M, Carpenter MK, Inokuma MS et al (2000) Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev Biol 227:271-278. doi:10.1006/dbio.2000.9912
10. Ahmed A, Tollefsbol T (2003) Telomeres, telomerase, and telo-merase inhibition: clinical implications for cancer. J Am Geriatr Soc 51:116-122. doi:10.1034/j.1601-5215.2002.51019.x (Pubitemid 36119944)
11. Hiyama K, Hirai Y, Kyoizumi S et al (1995) Activation of tel-omerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 55:3711-3715
12. Yui J, Chiu CP, Lansdorp PM (1998) Telomerase activity in candidate stem cells from fetal liver and adult bone marrow. Blood 91:3255-3262
13. Marcand S, Brevet V, Mann C et al (2000) Cell cycle restriction of telomere elongation. Curr Biol 10:487-490. doi:10.1016/ S0960-9822(00)00450-4
14. Diede SJ, Gottschling DE (1999) Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases ? and ?. Cell 99:723-733. doi:10.1016/S0092-8674(00)81670-0
15. Hiyama E, Hiyama K (2007) Telomere and telomerase in stem cells. Br J Cancer 96:1020-1024. doi:10.1038/sj.bjc.6603671 (Pubitemid 46608315)
16. Clarke MF, Fuller M (2006) Stem cells and cancer: two faces of eve. Cell 124:1111-1115. doi:10.1016/j.cell.2006.03.011
17. Ohyashiki JH, Sashida G, Tauchi T et al (2002) Telomeres and telomerase in hematologic neoplasia. Oncogene 21:680-687. doi:10.1038/sj.onc.1205075
18. Cheong HT, Park TM, Ikeda K et al (2003) Cell cycle analysis of bovine cultured somatic cells by flow cytometry. J Vet Res 51: 95-103
19. Shervington A, Patel R, Lu C et al (2007) Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma. Brain Res 1134:45-52. doi:10.1016/j.brainres.2006.11.093 (Pubitemid 46135546)
20. Shervington A, Lu C (2008) Expression of multidrug resistance genes in normal and cancer stem cells. Cancer Invest 26:535-542. doi:10.1080/ 07357900801904140 (Pubitemid 351892589)
21. Galderisi U, Cipollaro M, Giordano A (2006) Stem cells and brain cancer. Cell Death Differ 3:5-11. doi:10.1038/sj.cdd.4401757
22. Hemmati HD, Nakano I, Lazareff JA et al (2003) Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 100:15178-15183. doi:10.1073/pnas.2036535100 (Pubitemid 37518036)
23. Reya T, Morrison SJ, Clarke MF et al (2001) Stem cells, cancer, and cancer stem cells. Nature 414:105-111. doi:10.1038/35102167 (Pubitemid 33041634)
24. Reynolds BA, Weiss S (1996) Clonal and population analyses demonstrate that an EGF responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol 175:1-13. doi:10.1006/dbio. 1996.0090
25. Lu C, Shervington A (2008) Chemoresistance in gliomas. Mol Cell Biochem 312:71-80. doi:10.1007/s11010-008-9722-8
26. Seimiya H, Sawada H, Muramatsu Y, Shimizu M, Ohko K, Yamane K, Tsuruo T (2000) Involvement of 14-3-3 proteins in nuclear localization of telomerase. EMBO J 19:2652-2661. doi:10.1093/emboj/19.11.2652
27. Weng NP (2002) Regulation of telomerase expression in human lymphocytes. Springer Semin Immunopathol 24:23-33. doi:10.1007/ s00281-001-0093-4
28. Shervington A, Patel R (2008) Differential hTERT mRNA processing between young and older glioma patients. FEBS Lett 582:1707-1710. doi:10.1016/j.febslet. 2008.04.027
29. Kyo S et al (2003) Significance of immunological detection of human telomerase reverse transcriptase: re-evaluation of expression and localization of human telomerase reverse transcriptase. Am J Pathol 163:859-867
30. Patrawala L, Calhoun T, Schneider-Broussard R et al (2006) Side population is enriched in tumourigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumourigenic. Cancer Res 65:6207-6219. doi:10.1158/0008-5472.CAN-05-0592
31. Wang J, Sakariassen P, Tsinkalovsky O et al (2008) CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int J Cancer 122:761-768. doi:10.1002/ijc.23130
32. Saretzki G, Walter T, Atkinson S et al (2008) Downregulation of multiple stress defence mechanisms during differentiation of human embryonic stem cells. Stem Cells 26:455-464. doi:10.1634/stemcells.2007-0628 (Pubitemid 351413606)