Solubility of hydrophobic compounds in water-cosolvent mixtures: Relation of solubility with water-cosolvent interactions

Journal of Pharmaceutical Sciences

Volumn 99, Issue 1, 2010, Pages 293-302

  Miyako, Yasuhiro ^a,b   Zhao, Yinyan ^b   Takeshima, Kazuo ^a   Kataoka, Takahiro ^a   Handa, Tetsurou ^c   Pinal, Rodolfo ^b  

^a SHIONOGI AND CO LTD   (Japan)

^b PURDUE UNIVERSITY   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Interaction; Mixing; Preformulation; Solubility; Thermodynamics

Indexed keywords

BENZOCAINE; FUROSEMIDE; INDOMETACIN; ORGANIC COMPOUND; PHENACETIN; SOLVENT; WATER;

ARTICLE; DRUG SOLUBILITY; HYDROPHOBICITY; MATHEMATICAL MODEL;

EID: 73949160102     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21842     Document Type: Article

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