Identification of inflamed atherosclerotic plaque using123I-labeled Interleukin-2 scintigraphy in high-risk peritoneal dialysis patients: A pilot study

Peritoneal Dialysis International

Volumn 29, Issue 5, 2009, Pages 568-574

  Hubalewska Dydejczyk, Alicja ^a   Stompór, Tomasz ^b   Kalembkiewicz, Marta ^a   Krzanowski, Marcin ^b   Mikolajczak, Renata ^c   Sowa Staszczak, Anna ^a   Tabor Ciepiela, Barbara ^b   Karczmarczyk, Urszula ^d   Kuśnierz Cabala, Beata ^e   Sulowicz, Wladyslaw ^b  

^a Nuclear Medicine Unit   (Poland)

^b JAGIELLONIAN UNIVERSITY   (Poland)

^c INSTITUTE OF ATOMIC ENERGY   (Poland)

^d NATIONAL MEDICINES INSTITUTE   (Poland)

^e JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Atherosclerosis; Atherosclerotic plaque; Intima media thickness

Indexed keywords

BIOLOGICAL MARKER; IODINE RECOMBINANT INTERLEUKIN 2 I 123; RADIOPHARMACEUTICAL AGENT; RECOMBINANT INTERLEUKIN 2; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; INTERLEUKIN 2; RADIOACTIVE IODINE;

ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROTIC PLAQUE; CLINICAL ARTICLE; COMMON CAROTID ARTERY; COMORBIDITY; CONTROLLED STUDY; ECHOCARDIOGRAPHY; FEMALE; HEART SCINTISCANNING; HIGH RISK PATIENT; HUMAN; ISOTOPE TRACING; KIDNEY FAILURE; MALE; PERITONEAL DIALYSIS; PILOT STUDY; PRIORITY JOURNAL; RISK ASSESSMENT; TREATMENT DURATION; CAROTID ARTERY DISEASE; CAROTID ARTERY OBSTRUCTION; CHRONIC KIDNEY FAILURE; INFLAMMATION; MIDDLE AGED; RISK FACTOR; SCINTISCANNING;

CAROTID ARTERY DISEASES; CAROTID ARTERY, COMMON; CAROTID STENOSIS; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-2; IODINE RADIOISOTOPES; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PERITONEAL DIALYSIS; RISK FACTORS;

EID: 73949153258     PISSN: 08968608     EISSN: 17184304     Source Type: Journal    
DOI: 10.1177/089686080902900516     Document Type: Article

References (24)

1. Go AS, Chertow GM, Fan D, McCullogh CE, Hsu CY. Chronic kidney disease and the risk of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296-305.
2. Anavekar NS, McMurray JJ, Velasquez EJ, Solomon SD, Kober L, Rouleau JL, et al. Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. N Engl J Med 2004; 351:1285-95.
3. Shik J, Parfrey PS. The clinical epidemiology of cardiovascular disease in chronic kidney disease. Curr Opin Nephrol Hypertens 2005; 14:550-7.
4. Foley RN, Collins AJ. End-stage renal disease in the United States: an update from the United States Renal Data System. J Am Soc Nephrol 2007; 18:2644-8.
5. Rayner HC, Pisoni RL, Bommer J, Canaud B, Hecking E, Locatelli F, et al. Mortality and hospitalization in haemodialysis patients in five European countries: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant 2004; 19:108-20.
6. Kalantar-Zadeh K. Recent advances in understanding the malnutrition-inflammation-cachexia syndrome in chronic kidney disease patients: what is next? Semin Dial 2005; 18:365-9.
7. Pecoits-Filho R, Lindholm B, Stenvinkel P. The malnutrition, inflammation, and atherosclerosis (MIA) syndrome-the heart of the matter. Nephrol Dial Transplant 2002; 17(Suppl 11):28-31.
8. Zielinski T, Dzielinska Z, Januszewicz A, Rynkun D, Makowiecka-Ciesla M, Tyczynski P, et al. Carotid intimamedia thickness as a marker of cardiovascular risk in hypertensive patients with coronary artery disease. Am J Hypertens 2007; 20:1058-64.
9. Nishizawa Y, Shoji T, Maekawa K, Nagasue K, Okuno S, Kim M, et al. Intima-media thickness of carotid artery predicts cardiovascular mortality in hemodialysis patients. Am J Kidney Dis 2003; 41(Suppl 1):S76-9.
10. Kato A, Takita T, Maruyama, Y, Kumagai H, Hishida A. Impact of carotid atherosclerosis on long-term mortality in chronic hemodialysis patients. Kidney Int 2003; 64: 1472-9.
11. Szeto CC, Chow KM, Woo KS, Chook P, Ching-Ha Kwan B, Leung CB, et al. Carotid intima-media thickness predicts cardiovascular diseases in Chinese predialysis patients with chronic kidney disease. J Am Soc Nephrol 2007; 18: 1966-72.
12. Papagianni A, Kalovoulos M, Kirmizis D, Vainas A, Belechri AM, Alexopoulos E, et al. Carotid atherosclerosis is associated with inflammation and endothelial cell adhesion molecules in chronic haemodialysis patients. Nephrol Dial Transplant 2003; 18:113-19.
13. Ohkuma T, Minagawa T, Takada N, Ohno M, Oda H, Ohashi H. C-reactive protein, lipoprotein (a), homocysteine, and male sex contribute to carotid atherosclerosis in peritoneal dialysis patients. Am J Kidney Dis 2003; 42:355-61.
14. Buyukhatipoglu H, Tiryaki O, Tahta K, Usalan C. Inflammation as a risk factor for carotid intimal-medial thickening, a measure of subclinical atherosclerosis in haemodialysis patients: the role of chlamydia and cytomegalovirus infection. Nephrology 2007; 12:25-32.
15. Stompor T, Krasniak A, Sulowicz W, Dembinska-Kiec A, Janda K, Wojcik K, et al. Changes in common carotid artery intima-media thickness over one year in patients on peritoneal dialysis. Nephrol Dial Transplant 2005; 20: 404-12.
16. McKay CR, Shavelle DM. Intravascular ultrasound in the coronary arteries. Semin Vasc Surg 2006; 19:132-8.
17. Tearney GJ, Yabushita H, Houser SL, Aretz HT, Jang IK, Schlendorf KH, et al. Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography. Circulation 2003; 107:113-19.
18. Kubo T, Imanishi T, Takarada S, Kuroi A, Ueno S, Yamano T, et al. Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy. J Am Coll Cardiol 2007; 50:933-9.
19. Motoyama S, Kondo T, Anno H, Sugiura A, Ito Y, Mori K, et al. Atherosclerotic plaque characterization by 0.5-mmslice multislice computed tomographic imaging. Circ J 2007; 71:363-6.
20. Annovazzi A, Bonanno E, Arca M, D'Alessandria C, Marcoccos A, Spagnoli LG, et al. 99mTc-interleukin-2 scintigraphy for the in vivo imaging of vulnerable atherosclerotic plaque. Eur J Nucl Med Mol Imaging 2006; 33:117-26.
21. Salacinski PR, McLean C, Sykes JEC, Clement-Jones VV, Lowry PJ. Iodination of proteins, glycoproteins, and peptides using a solid-phase oxidizing agent 1,3,4,6-tetrachloro-3 alpha, 6 alpha-diphenylglycouril (Iodogen). Anal Biochem 1981; 117:136-46.
22. Behr TM, Gotthardt M, Becker W, Behe M. Radioiodination of monoclonal antibodies, proteins and peptides for diagnosis and therapy. A review of standardized, reliable and safe procedures for clinical grade levels kBq to GBq in the Gottingen/Marburg experience. Nuklearmedizin 2002; 41:71-9.
23. Visser GW, Klok RP, Gebbink GW, ter Linden T, van Dongen GA, Molthoff CF. Optimal quality (131)-monoclonal antibodies on high-dose labeling in a large reaction volume and temporarily coating the antibody with Iodo-Gen. J Nucl Med 2001; 42:509-19.
24. Wang AY, Ho SS, Liu EK, Chan IH, Ho S, Sanderson JE, et al. Differential associations of traditional and non-traditional risk factors with carotid intima-media thickening and plaque in peritoneal dialysis patients. Am J Nephrol 2007; 27:458-65.