CYP7B1-mediated metabolism of 5α-androstane-3α,17β-diol (3α-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1791, Issue 12, 2009, Pages 1206-1215

  Pettersson, Hanna ^a   Lundqvist, Johan ^a   Oliw, Ernst ^a   Norlin, Maria ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

5 Androstane 3 ,17 diol; Androgen; CYP7B1; Neurosteroid; Steroid metabolism

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANDROGEN; ANDROSTANEDIOL; ANDROSTANOLONE; CYTOCHROME P450; CYTOCHROME P450 7B1; NEUROSTEROID; OXYGENASE; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROID MONOOXYGENASE; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANDROGEN RECEPTOR; CYP7B1 PROTEIN, HUMAN; CYP7B1 PROTEIN, MOUSE; ESTROGEN RECEPTOR BETA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RECOMBINANT PROTEIN;

ANIMAL TISSUE; ARTICLE; CELL LEVEL; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HORMONE METABOLISM; HUMAN; HUMAN CELL; HYDROXYLATION; KNOCKOUT MOUSE; LIVER MICROSOME; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SWINE; ANIMAL; BIOCATALYSIS; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; MASS SPECTROMETRY; METABOLISM; MOUSE MUTANT;

MUS; SUS;

ANDROGENS; ANDROSTANE-3,17-DIOL; ANIMALS; BIOCATALYSIS; CELL LINE; ESTROGEN RECEPTOR BETA; HUMANS; HYDROXYLATION; MASS SPECTROMETRY; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, KNOCKOUT; MICROSOMES, LIVER; MODELS, BIOLOGICAL; NADP; NEUROTRANSMITTER AGENTS; RECEPTORS, ANDROGEN; RECOMBINANT PROTEINS; STEROID HYDROXYLASES; SUS SCROFA;

EID: 73949137391     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2009.08.010     Document Type: Article

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