Oxidative stress of burkholderia cenocepacia induces insertion sequence-mediated genomic rearrangements that interfere with macrorestriction-based genotyping

Journal of Clinical Microbiology

Volumn 48, Issue 1, 2010, Pages 34-40

  Drevinek, Pavel ^a,c   Baldwin, Adam ^b   Lindenburg, Laurens ^a   Joshi, Lovleen Tina ^a   Marchbank, Angela ^a   Vosahlikova, Sarka ^c   Dowson, Christopher G ^b   Mahenthiralingam, Eshwar ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSPOSASE;

ARTICLE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM ISOLATE; BURKHOLDERIA CENOCEPACIA; CONTROLLED STUDY; DNA PROBE; FRAMESHIFT MUTATION; GENE INSERTION SEQUENCE; GENE REARRANGEMENT; GENETIC VARIABILITY; GENOTYPE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SOUTHERN BLOTTING;

BACTERIAL TYPING TECHNIQUES; BURKHOLDERIA; BURKHOLDERIA INFECTIONS; CLUSTER ANALYSIS; CYSTIC FIBROSIS; CZECH REPUBLIC; DISEASE OUTBREAKS; DNA FINGERPRINTING; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; GENETIC VARIATION; GENOTYPE; HUMANS; MOLECULAR EPIDEMIOLOGY; OXIDATIVE STRESS; RECOMBINATION, GENETIC;

BURKHOLDERIA CENOCEPACIA;

EID: 73949128999     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.01433-09     Document Type: Article

References (22)

1. Baldwin, A., E. Mahenthiralingam, P. Drevinek, P. Vandamme, J. R. Govan, D. J. Waine, J. J. LiPuma, L. Chiarini, C. Dalmastri, D. A. Henry, D. P. Speert, D. Honeybourne, M. C. Maiden, and C. G. Dowson. 2007. Environmental Burkholderia cepacia complex isolates in human infections. Emerg. Infect. Dis. 13:458-461.
2. Baldwin, A., E. Mahenthiralingam, K. M. Thickett, D. Honeybourne, M. C. Maiden, J. R. Govan, D. P. Speert, J. J. Lipuma, P. Vandamme, and C. G. Dowson. 2005. Multilocus sequence typing scheme that provides both species and strain differentiation for the Burkholderia cepacia complex. J. Clin. Microbiol. 43:4665-4673.
3. Coenye, T., T. Spilker, A. Martin, and J. J. LiPuma. 2002. Comparative assessment of genotyping methods for epidemiologic study of Burkholderia cepacia genomovar III. J. Clin. Microbiol. 40:3300-3307.
4. Diaz, P. I., N. Slakeski, E. C. Reynolds, R. Morona, A. H. Rogers, and P. E. Kolenbrander. 2006. Role of oxyR in the oral anaerobe Porphyromonas gingivalis. J. Bacteriol. 188:2454-2462.
5. Drevinek, P., M. T. Holden, Z. Ge, A. M. Jones, I. Ketchell, R. T. Gill, and E. Mahenthiralingam. 2008. Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum. BMC Infect. Dis. 8:121.
6. Drevinek, P., S. Vosahlikova, O. Cinek, V. Vavrova, J. Bartosova, P. Pohunek, and E. Mahenthiralingam. 2005. Widespread clone of Burkholderia cenocepacia in cystic fibrosis patients in the Czech Republic. J. Med. Microbiol. 54:655-659.
7. Holden, M. T., H. M. Seth-Smith, L. C. Crossman, M. Sebaihia, S. D. Bentley, A. M. Cerdeno-Tarraga, N. R. Thomson, N. Bason, M. A. Quail, S. Sharp, I. Cherevach, C. Churcher, I. Goodhead, H. Hauser, N. Holroyd, K. Mungall, P. Scott, D. Walker, B. White, H. Rose, P. Iversen, D. Mil-Homens, E. P. Rocha, A. M. Fialho, A. Baldwin, C. Dowson, B. G. Barrell, J. R. Govan, P. Vandamme, C. A. Hart, E. Mahenthiralingam, and J. Parkhill. 2009. The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. J. Bacteriol. 191:261-277.
8. Ilves, H., R. Horak, and M. Kivisaar. 2001. Involvement of sigma(S) in starvation-induced transposition of Pseudomonas putida transposon Tn4652. J. Bacteriol. 183:5445-5448.
9. Keith, K. E., and M. A. Valvano. 2007. Characterization of SodC, a periplasmic superoxide dismutase from Burkholderia cenocepacia. Infect. Immun. 75:2451-2460.
10. Lefebre, M., and M. Valvano. 2001. In vitro resistance of Burkholderia cepacia complex isolates to reactive oxygen species in relation to catalase and superoxide dismutase production. Microbiology 147:97-109.
11. Lessie, T. G., W. Hendrickson, B. D. Manning, and R. Devereux. 1996. Genomic complexity and plasticity of Burkholderia cepacia. FEMS Microbiol. Lett. 144:117-128.
12. Mahenthiralingam, E., A. Baldwin, and C. G. Dowson. 2008. Burkholderia cepacia complex bacteria: opportunistic pathogens with important natural biology. J. Appl. Microbiol. 104:1539-1551.
13. Mahenthiralingam, E., A. Baldwin, P. Drevinek, E. Vanlaere, P. Vandamme, J. J. Lipuma, and C. G. Dowson. 2006. Multilocus sequence typing breathes life into a microbial metagenome. PLoS One 1:e17.
14. Mahenthiralingam, E., M. E. Campbell, D. A. Henry, and D. P. Speert. 1996. Epidemiology of Burkholderia cepacia infection in patients with cystic fibrosis: analysis by randomly amplified polymorphic DNA fingerprinting. J. Clin. Microbiol. 34:2914-2920.
15. Mahenthiralingam, E., T. A. Urban, and J. B. Goldberg. 2005. The multifarious, multireplicon Burkholderia cepacia complex. Nat. Rev. Microbiol. 3:144-156.
16. Mahillon, J., and M. Chandler. 1998. Insertion sequences. Microbiol. Mol. Biol. Rev. 62:725-774.
17. Ohtsubo, Y., H. Genka, H. Komatsu, Y. Nagata, and M. Tsuda. 2005. High-temperature-induced transposition of insertion elements in Burkholderia multivorans ATCC 17616. Appl. Environ. Microbiol. 71:1822-1828.
18. O'Sullivan, L. A., A. J. Weightman, T. H. Jones, A. M. Marchbank, J. M. Tiedje, and E. Mahenthiralingam. 2007. Identifying the genetic basis of ecologically and biotechnologically useful functions of the bacterium Burkholderia vietnamiensis. Environ. Microbiol. 9:1017-1034.
19. Speert, D. P., D. Henry, P. Vandamme, M. Corey, and E. Mahenthiralingam. 2002. Epidemiology of Burkholderia cepacia complex in patients with cystic fibrosis, Canada. Emerg. Infect. Dis. 8:181-187.
20. + Pseudomonas (Burkholderia) cepacia causing CF centre epidemics in North America and Britain. Nat. Med. 1:661-666.
21. Vanlaere, E., A. Baldwin, D. Gevers, D. Henry, E. De Brandt, J. J. LiPuma, E. Mahenthiralingam, D. P. Speert, C. Dowson, and P. Vandamme. 2009. Taxon K, a complex within the Burkholderia cepacia complex, comprises at least two novel species, Burkholderia contaminans sp. nov. and Burkholderia lata sp. nov. Int. J. Syst. Evol. Microbiol. 59:102-111.
22. Vanlaere, E., J. J. Lipuma, A. Baldwin, D. Henry, E. De Brandt, E. Mahenthiralingam, D. Speert, C. Dowson, and P. Vandamme. 2008. Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia complex. Int. J. Syst. Evol. Microbiol. 58:1580-1590.