Treatment of late-life depression alleviates caregiver burden

Journal of the American Geriatrics Society

Volumn 58, Issue 1, 2010, Pages 23-29

  Martire, Lynn M ^a   Schulz, Richard ^a   Reynolds III, Charles F ^a   Karp, Jordan F ^a   Gildengers, Ariel G ^a   Whyte, Ellen M ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Burden; Caregiver; Depression; Family; Treatment

Indexed keywords

ESCITALOPRAM;

ADULT; AGED; ARTICLE; CAREGIVER; CAREGIVER BURDEN; CLINICAL TRIAL; CONTROLLED STUDY; DRUG DOSE INCREASE; FAMILY; FEMALE; GERONTOPSYCHIATRY; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MONOTHERAPY; OUTPATIENT DEPARTMENT; PRIMARY MEDICAL CARE; PSYCHOTHERAPY; REMISSION; THERAPY EFFECT;

AGED; ANTIDEPRESSIVE AGENTS; CAREGIVERS; COST OF ILLNESS; DEPRESSION; FAMILY HEALTH; FEMALE; HUMANS; MALE; PSYCHOTHERAPY;

EID: 73949127469     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2009.02610.x     Document Type: Article

References (41)

1. Bruce ML, Ten Have TR, Reynolds CF III. et al. Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: A randomized controlled trial. JAMA 2004 291 : 1081 1091.
2. Reynolds CF III., Dew MA, Pollock BG et al. Maintenance treatment of major depression in old age. N Engl J Med 2006 354 : 1130 1138.
3. Unutzer J, Katon W, Callahan CM et al. Collaborative care management of late-life depression in the primary care setting: A randomized controlled trial. JAMA 2002 288 : 2836 2845.
4. Unutzer J, Katon WJ, Fan MY et al. Long-term cost effects of collaborative care for late-life depression. Am J Manage Care 2008 14 : 95 100.
5. Lenze EJ, Dew MA, Mazumdar S et al. Combined pharmacotherapy and psychotherapy as maintenance treatment for late-life depression: Effects on social adjustment. Am J Psychiatry 2002 159 : 466 468.
6. Katon WJ, Schoenbaum M, Fan MY et al. Cost-effectiveness of improving primary care treatment of late-life depression. Arch Gen Psychiatry 2005 62 : 1313 1320.
7. Langa KM, Valenstein MA, Fendrick AM et al. Extent and cost of informal caregiving for older Americans with symptoms of depression. Am J Psychiatry 2004 161 : 857 863.
8. Schulz R, Beach SR. Caregiving as a risk factor for mortality: The Caregiver Health Effects Study. JAMA 1999 282 : 2215 2219.
9. Vitaliano PP, Zhang J, Scanlan J. Is caregiving hazardous to one's physical health? A meta-analysis. Psychol Bull 2003 129 : 946 972.
10. Andreescu C, Mulsant BH, Houck PR et al. Empirically derived decision trees for the treatment of late-life depression. Am J Psychiatry 2008 165 : 855 862.
11. Mulsant BH, Houck PR, Gildengers AG et al. What is the optimal duration of a short-term antidepressant trial when treating geriatric depression? J Clin Psychopharmacol 2006 6 : 113 120.
12. Reynolds CF, Dew MA, Martire LM et al. Treating major depression to remission in older adults: A controlled evaluation of combined interpersonal psychotherapy and escitalopram. Int J Geriatr Psychiatry. In press.
13. Lingler JH, Martire LM, Schulz R. Caregiver-specific outcomes in antidementia clinical drug trials: A systematic review and meta-analysis. J Am Geriatr Soc 2005 53 : 983 990.
14. Lyketsos CG, DelCampo L, Steinberg M et al. Treating depression in Alzheimer's disease: Efficacy and safety of sertraline therapy, and the benefits of depression reduction: The DIADS. Arch Gen Psychiatry 2003 60 : 737 746.
15. Hinrichsen GA, Hernandez NA. Factors associated with recovery from and relapse into major depressive disorder in the elderly. Am J Psychiatry 1993 150 : 1820 1825.
16. Teri L, Truax P, Logsdon R et al. Assessment of behavioral problems in dementia: The Revised Memory and Behavior Problems Checklist. Psychol Aging 1992 7 : 622 631.
17. Zarit SH, Zarit JM. The Memory and Behaviour Problems Checklist 1987R and the Burden Interview (Technical report). State College, PA: Pennsylvania State University, 1987.
18. First MB, Gibbon M, Spitzer RL et al. Structured Clinical Interview for DSM-IV Axis 1 Disorders, SCID 1: Clinical Version, Administration Booklet. Washington, DC : American Psychiatric Press, 1997.
19. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960 23 : 56 62.
20. Folstein MF, Folstein SE, McHugh PR. Mini-mental state: A practical method for grading the state of patients for the clinician. J Psychiatr Res 1975 12 : 189 198.
21. Hinrichsen GA. Adjustment of caregivers to depressed older adults. Psychol Aging 1991 6 : 631 639.
22. Perlick DA, Rosenheck RR, Clarkin JF et al. Impact of family burden and affective response on clinical outcome among patients with bipolar disorder. Psychiatr Serv 2004 55 : 1029 1035.
23. Pfeiffer E. A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J Am Geriatr Soc 1975 23 : 433 441.
24. Miller MD, Paradis CF, Houck PR et al. Rating chronic medical illness burden in geropsychiatric practice and research: Application of the Cumulative Illness Rating Scale. Psychiatry Res 1992 41 : 237 248.
25. Ware JE, Shelbourne CD. The MOS 36-item short-form health survey (SF-36): I: Conceptual framework and item selection. Med Care 1992 30 : 473 483.
26. Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Measure 1977 1 : 385 401.
27. Butters MA, Whyte EM, Nebes RD et al. The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry 2004 61 : 587 595.
28. Lenze EJ, Rogers JC, Martire LM et al. The association of late-life depression and anxiety with physical disability: A review of the literature and prospectus for future research. Am J Geriatr Psychiatry 2001 9 : 113 135.
29. Hebert R, Bravo G, Preville M. Reliability, validity and reference values of the Zarit Burden Interview for assessing informal caregivers of community-dwelling older persons with dementia. Can J Aging 2000 19 : 494 507.
30. Schreiner AS, Morimoto T, Arai Y et al. Assessing family caregiver's mental health using a statistically derived cut-off score for the Zarit Burden Interview. Aging Mental Health 2006 10 : 107 111.
31. Wisniewski S, Belle SH, Coon DW et al. The Resources for Enhancing Alzheimer's Caregiver Health (REACH): Project design and baseline characteristics. Psychol Aging 2003 18 : 375 384. (Pubitemid 37152057)
32. Schulz R, Martire LM, Klinger JN. Evidence-based caregiver interventions in geriatric psychiatry. Psychiatr Clin North Am 2005 28 : 1007 1038.
33. Martire LM, Schulz R. Involving family in psychosocial interventions for chronic illness. Curr Direct Psychol Sci 2007 16 : 90 94.
34. Miklowitz DJ, Simoneau TL, George EL et al. Family-focused treatment of bipolar disorder: 1-year effects of a psychoeducational program in conjunction with pharmacotherapy. Biol Psychiatry 2000 48 : 582 592.
35. Charney DS, Reynolds CF III., Lewis L et al. Depression and bipolar support alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry 2003 60 : 664 672. (Pubitemid 36818628)
36. Sewitch MJ, McCusker J, Dendukuri N et al. Depression in frail elders: Impact on family caregivers. Int J Geriatr Psychiatry 2004 19 : 655 665.
37. Scazufca M, Menezes PR, Almeida OP. Caregiver burden in an elderly population with depression in São Paulo, Brazil. Soc Psychiatry Psychiatr Epidemiol 2002 27 : 416 422.
38. Monin JK, Schulz R. Interpersonal effects of suffering in older adult caregiving relationships. Psychol Aging 2009 24 : 681 695.
39. Schulz R, Hebert RS, Dew MA et al. Patient suffering and caregiver compassion: New opportunities for research, practice, and policy. Gerontologist 2007 47 : 4 13.
40. Ayalon L, Arean PA, Alvidrez J. Adherence to antidepressant medications in black and Latino elderly patients. Am J Geriatr Psychiatry 2005 13 : 572 580.
41. Freimuth VS, Quinn SC, Thomas SB et al. African American's views on research and the Tuskegee syphilis study. Soc Sci Med 2001 52 : 797 808.