Evidence for medium chain triglycerides in the treatment of primary intestinal lymphangiectasia

European Journal of Pediatric Surgery

Volumn 19, Issue 4, 2009, Pages 241-245

  Desai, A P ^a   Guvenc, B H ^b   Carachi, R ^c  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b Anadolu Medical Center   (Turkey)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Intestinal lymphangiectasia; Medium chain triglycerides; Nutrition; Review

Indexed keywords

MEDIUM CHAIN TRIACYLGLYCEROL; TRIACYLGLYCEROL;

ABDOMINAL DISTENSION; ARTICLE; ASCITES; BODY WEIGHT; CHILD; CHILD NUTRITION; CHILDHOOD MORTALITY; CLINICAL ARTICLE; COMPRESSION THERAPY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIET; EDEMA; FEMALE; HUMAN; INTESTINE LYMPHANGIECTASIA; LAPAROTOMY; LOW FAT DIET; LYMPH NODE BIOPSY; LYMPHEDEMA; MALE; NEWBORN; NUTRITION; PARACENTESIS; PROTEIN DIET; TOTAL PARENTERAL NUTRITION; TREATMENT OUTCOME; CASE REPORT; DIET THERAPY; FAT INTAKE; MORTALITY; PRESCHOOL CHILD;

CHILD; CHILD, PRESCHOOL; DIETARY FATS; FEMALE; HUMANS; INFANT, NEWBORN; LYMPHANGIECTASIS, INTESTINAL; MALE; TREATMENT OUTCOME; TRIGLYCERIDES;

EID: 73949114609     PISSN: 09397248     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0029-1216389     Document Type: Article

References (50)

1. Warwick WJ, Holman RT, Quie PG et al. Chylous ascites and lymphoedema. J Dis Child 1959; 98: 317-329
2. Jarnum S, Petersen VP. Protein-losing enteropathy. Lancet 1961; 1: 417-421
3. Cottom DG, London Dr, Wilson BDR. Neonatal eedema due to exudative enteropathy. Lancet 1961; 1: 327-330
4. Waldmann TA, Steinfeld JL, Dutcher TF et al. The role of the gastrointestinal system in "idiopathic hypoproteinemia". Gastroenterology 1961; 41: 197-200
5. Waldmann TA, Schwab PJ. IgG (7 gamma globulin) metabolism in hypogammaglobulinemia: studies in patients with defective gamma globulin synthesis, gastrointestinal protein loss, or both. J Clin Invest 1965; 44: 1523-1533
6. Browse NL, Wilson NM, Russo F et al. Aetiology and treatment of chylous ascites. Br J Surg 1992; 79: 1145-1150
7. Fox U, Lucani G. Disorders of the intestinal lymphatic system. Lymphology 1993; 26: 61-66
8. Fonkalsrun EW. Congenital malformation of the lymphatic system. Seminars in Pediatric Surgery 1994; 3: 62-69
9. Vardy PA, Lebenthal E, Shwachman H. Intestinal lymphangiectasia: A reappraisal. Pediatrics 1975; 55: 842-851
10. Nazer HM, Abutalib H, Hugosson C et al. Intestinal lymphangiectasia masquerading as coeliac disease. Ann Trop Paediatr 1991; 11: 349-355
11. Maya MM, Friedwald J. Intestinal lymphangiectasia: ultrasound evaluation of a case simulating appendicitis. Abdom Imaging 1993; 18: 27-28
12. Perisic VN, Kokai G. Coeliac disease and lymphangiectasia. Arch Dis Child 1992; 67: 134-136
13. Vallet HL, Holtzapple PG, Eberlein WR et al. Noonan syndrome with intestinal lymphangiectasis. A metabolic and anatomic study. J Pediatr 1972; 80: 269-274
14. Perisic VN, Kokai G. Bleeding from duodenal lymphangiectasia. Archives Dis Childhood 1991; 66: 153-154
15. Lee WS, Boey CCM, Goh AYT et al. Intestinal lymphangiectasia - A report of three Chinese children in Malaysia. Singapore Med J 1998; 39: 418-41 421
16. Strober W, Wochner RD, Carbone PP et al. Intestinal lymphangiectasia: A protein-losing enteropathy with hypogammaglobulinaemia, lymphocytopenia and impaired homograft rejection. J Clin Invest 1967; 46: 1643-1656
17. O'Donnell D, Myers AM. Intestinal lymphangiectasia and protein losing enteropathy, toxic copper accumulation and hypoparathyroidism. Aust NZ J Med 1990; 20: 167-169
18. Stoelinga GBA, Van Munster PJJ, Slooff JP. Chylous Effusions into the intestine in a patient with protein-losing enteropathy. Pediatrics 1963; 31: 1011-1018
19. Mistilis SP, Skyring AP, Stephen DD. Intestinal lymphangiectasia. Mechanism of enteric loss of plasma-protein and fat. Lancet 1965; 1: 77-79
20. Waldmann TA. Protein-losing enteropathy. Gastroenterology 1966; 50: 422-443
21. Jeejeebhoy KN. Cause of hypoalbuminaemia in patients with gastrointestinal and cardiac disease. Lancet 1962; 1: 343-348
22. Browse NL, Stewart G. Lymphoedema: pathophysiology and classification. J Cardiovasc Surg 1985; 26: 91-105
23. Ores CN, Ores RO, Denning CR et al. Hypercatabolic hypoproteinemia with lymphangiectasia of the small bowel. Pediatrics 1966; 69: 439-448
24. Heresbach D, Raoul J, Genetet N et al. Immunological study in primary intestinal lymphangiectasia. Digestion 1994; 55: 59-64
25. Leyland FC, Fosbrooke AS, Lloyd JK et al. Use of medium-chain triglycerides in children with malabsorption. Arch Dis Childh 1969; 44: 170-179
26. Jeffries GH, Chapman A, Sleisenger MH. Low-fat diet in intestinal lymphangiectasia. Its effect on albumin metabolism. New Engl J Med 1964; 270: 761-766
27. Mine K, Matsubayashi S, Nakai Y et al. Intestinal lymphangiectasia markedly improved with antiplasmin therapy. Gastroenterology 1989; 96: 1596-1599
28. Takami A, Nakao S, Sugimori N et al. Management of disseminated intra-abdominal lymphangiomatosis with protein-losing enteropathy and intestinal bleeding. Southern Medical Journal 1995; 88: 1156-1158
29. Holt PR. Dietary treatment of protein loss in intestinal lymphangiectasia. Pediatrics 1964; 34: 629-635
30. Rosen FS, Smith DH, Earle R et al. The etiology of hypoproteinemia in a patient with chylous ascites. Pediatrics 1962; 30: 696-706
31. Levine C. Primary disorders of the lymphatic vessels - A unified concept. J Paed Surg 1989; 24: 233-240
32. Parfitt AM. Familial Neonatal hypoproteinaemia with exudative enteropathy and intestinal lymphangiectasis. J Dis Child 1966; 41: 54-62
33. Tift WL, Lloyd JK. Intestinal lymphangiectasia. Long term results with MCT diet. Arch Dis Childh 1975; 50: 269-276
34. Bereket A, Lowerheim M, Blethen SL et al. Intestinal lymphangiectasia in a patient with autoimmune polyglandular disease type 1 and steatorrhoea. J Clin Endocrinol Metab 1995; 80: 933-935
35. Roisman I, Manny J, Fields S et al. Intra-abdominal lymphangioma. Br J Surg 1989; 76: 485-489
36. Haddad HM, Wilkins L. Congenital abnormalities associates with gonadal aplasia. Pediatrics 1959; 23: 885-902
37. Dobbins WO. Hypo-beta-lipoparoteinemia and intestinal lymphangiectasia. Arch Intern Med 1968; 122: 31-38
38. Urioste M, Rodriguez JI, Barcia JM et al. Persistence of Mullerian derivatives, lymphangiectasis, hepatic failure, postaxial polydactyly, renal and cranio-facial anomalies. Am J Med Gen 1993; 47: 494-503
39. Cormier-Daire V, Lyonnet S, Lehnert A et al. Craniosynostosis and kidney malformation in a case of Hennekam Syndrome. Am J Med Gen 1995; 57: 66-68
40. Erdem G, Oran O, Kotiloglu E et al. Intestinal lymphangiectasia in a patient with Zellweger cerebrohepatorenal syndrome. Am J Med Gen 1995; 58: 152-154
41. Weiden PL, Blaese RM, Strober W et al. Impaired lymphocyte transformation in intestinal lymphangiectasia: evidence for at least two functionally distinct lymphocyte populations in man. J Clin Invest 1972; 51: 1319-1325
42. Murphy EA. N-Familial Lymphatic Dysplasia with Intestinal Lymphangiectasia. Clinical Delineation of Birth Defects of the Gastro-intestinal Tract including Liver and Pancreas. Baltimore: Williams and Wilkins; 1972; Part XIII: 180-181
43. Aoyagi K, Mitsuo I, Takashi Y et al. Characteristic endoscopic features of intestinal lymphangiectasia: correlation with histological findings. Hepatogastroenterology 1997; 44: 133-138
44. Barnes RE, DeRidder PH. Fat absorption in patients with functional intestinal lymphangiectasia and lymphangiectic cysts. Am J Gastroenterol 1993; 88: 887-890
45. Salomons HA, Kramer P, Nikulasson S et al. Endoscopic features of long-standing primary intestinal lymphangiectasia. Gastrointestinal Endoscopy 1995; 41: 516-518
46. Patel AS, DeRidder PH. Endoscopic appearance and significance of functional intestinal lymphangiectasia of the duodenal mucosa. Gastrointest Endosc 1990; 36: 367-368
47. Antao B, Bishop J, Shawis R et al. Clinical application and diagnostic yield of wireless capsule endoscopy in children. J Laparoendosc Adv Surg Tech A 2007; 17: 364-370
48. Hubalewska- Hola A, Sowa- Staszczak A, Szczerbinski T et al. Protein losing enteropathy detected by Tc99m-labelled serum albumin abdominal scintigraphy - case report. Przegl Lek 2003; 60: 606-608
49. Kuroiwa G, Takayama T, Sato Y et al. Primary intestinal lymphangiectasia successfully treated with octreotide. J Gastroenterology 2001; 36: 129-132
50. Makhija S, von der Weid Py, Meddings J et al. Octreotide in intestinal lymphangiectasia: lack of a clinical response and failure to alter lymphatic function in a guinea pig model. Can J Gastroenterol 2004; 18: 681-685