Recombinant blood group proteins for use in antibody screening and identification tests

Current Opinion in Hematology

Volumn 16, Issue 6, 2009, Pages 473-479

  Seltsam, Axel ^a   Blasczyk, Rainer ^b  

^a Institute Springe   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Antibody screening; Blood group; Recombinant proteins

Indexed keywords

ANTIBODY; BLOOD GROUP ANTIGEN; RECOMBINANT PROTEIN;

ANTIBODY DETECTION; ANTIBODY SCREENING; ANTIBODY SPECIFICITY; BLOOD GROUP; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; HUMAN; PRIORITY JOURNAL; PROTEIN MICROARRAY; REVIEW; ANALYTICAL EQUIPMENT; CHEMISTRY; METHODOLOGY;

ANTIBODIES; BLOOD GROUP ANTIGENS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; REAGENT KITS, DIAGNOSTIC; RECOMBINANT PROTEINS;

EID: 73949113990     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0b013e3283319a06     Document Type: Review

References (68)

1. Landsteiner K. About agglutination of normal human blood. Wien Wochenschr 1901; 14:1132-1134.
2. Coombs RRA, Mourant AE, Race RR. A new test for the detection of weak and "Incomplete" Rh agglutinins. Br J Exp Pathol 1945; 26:255-266.
3. Reid ME, Lomas-Franols C. Blood group antigen faotsbook. 2nd ed. San Diego, CA: Academic Press; 2004.
4. Reid ME. Applications of DNA-based assays in blood group antigen and antibody identification. Transfusion 2003; 43:1748-1757.
5. Yazdanbakhsh K. Applications of blood group antigen expression systems for antibody detection and identification. Transfusion 2007; 47:85S-88S. (Pubitemid 46934301)
6. Alzari PM, Lascombe MB, Poljak RJ. Three-dimensional structure of anti-bodies. Annu Rev Immunol 1988; 6:555-580.
7. lssitt PD, Anstee DJ. Applied blood group serology. 4th ed. Durham: Mont-gomery Scientific Publication; 1998.
8. Yin J, Li G, Ren X, Herrler G. Select what you need: A comparative evaluation of the advantages and limitations of frequently used expression systems for foreign genes. J Biotechnol 2007; 127:335-347. (Pubitemid 44827384)
9. Seltsam A, Grüger D, Blasczyk R. Prokaryotic versus eukaryotic recombinant Lutheran blood group protein for antibody identification. Transfusion 2007; 47:1630-1636. (Pubitemid 47300608)
10. Mouro-Chanteloup I, D'Ambrosio AM, Gane P, et al. Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein. Blood 2002; 100:1038-1047.
11. Remaley AT, Ugorski M, Wu N, et al. Expression of human glycophorin A in wild type and glycosylation-deflcient Chinese hamster ovary cells. Role of N- and O-linked glycosylation in cell surface expression. J Biol Chem 1991 ; 266:24176-24183.
12. Ugorski M, Blackall DP, Pahlsson P, et al. Recombinant Miltenberger I and II human blood group antigens: the role of glycosylation In cell surface expression and antigenicity of glycophorin A. Blood 1993; 82:1913-1920. (Pubitemid 23278784)
13. Liu W, Avent ND Jones JW, et al. Molecular configuration of Rh D epitopes as defined by site-directed mutagenesis and expression of mutant Rh constructs in K562 erythroleukemia cells. Blood 1999; 94:3986-3996.
14. Liu W, Smythe JS, Scott ML, et al. Site-directed mutagenesis of the human D antigen: definition of D epitopes on the sixth external domain of the D protein expressed on K562 cells. Transfusion 1999; 39:17-25. (Pubitemid 29065955)
15. Smythe JS, Avent ND, Judson PA, et al. Expression of RHD and RHCE gene products using retroviral transduction of K562 cells establishes the molecular basis of Rh blood group antigens. Blood 1996; 87:2968-2973.
16. Ridgwell K, Dixey J, Scott ML. Production of soluble recombinant proteins with KeII, Duffy and Lutheran blood group antigen activity, and their use in screening human sera for KeII, Duffy and Lutheran antibodies. Transfus Med 2007; 17:384-394. (Pubitemid 47508651)
17. EI Nemer W, Rahuel C, Colin Y, et al. Organization of the human LU gene and molecular basis of the Lu(a)/Lu(b) blood group polymorphism. Blood 1997; 89:4608-4616. (Pubitemid 27260272)
18. Parsons SF, Malllnson G, Daniels GL, et al. Use of domain-deletion mutants to locate Lutheran blood group antigens to each of the five immunoglobulin superfamily domains of the Lutheran glycoprotein: elucidation of the molecular basis of the Lu(a)/Lu(b) and the Au(a)/Au(b) polymorphisms. Blood 1997; 89:4219-4225.
19. Lee S, Lin M, Mele A, et at. Proteolytic processing of big endothelln-3 by the kell blood group protein. Blood 1999; 94:1440-1450.
20. Russo D, Redman C, Lee S. Association of XK and Kell blood group proteins. J BIoI Chem 1998; 273:13950-13956. (Pubitemid 28268450)
21. Russo DC, Lee S, Reid M, Redman CM. Topology of Kell blood group protein and the expression of multiple antigens by transfected cells. Blood 1994; 84:3513-3523.
22. Seltsam A, Chesla S, Sinor L. Feasibility of antibody testing utilizing recombinant antigens in a solid phase assay. Transfusion 2008; 48 (suppl.):21A.
23. Yazdanbakhsh K, Lee S, Yu Q, Reid ME. Identification of a defect in the intracellular trafficking of a Kell blood group variant. Blood 1999; 94:310-318. (Pubitemid 29300163)
24. Yazdanbakhsh K, Oyen R, Yu Q, et al. High-level, stable expression of blood group antigens in a heterologous system. Am J Hematol 2000; 63:114-124. (Pubitemid 30120764)
25. Sheffield WP, Bhakta V, Branch DR, Denomme GA. Detection of antibodies reacting with the antithetical duffy blood group antigens Fy(a) and Fy(b) using recombinant fusion proteins containing the duffy extracellular domain. Transfus Apher Sci 2006; 35:207-216. (Pubitemid 44848410)
26. WasnlowskaK, Czerwinski M, Jachymek W, Lisowska E. Expression and binding properties of a soluble chimeric protein containing the N-terminal domain of the Duffy antigen. Blochem Biophys Res Commun 2000; 273:705-711. (Pubitemid 30599048)
27. Sidoux-Walter F. , Lucien N, Nissinen R, et al. Molecular heterogeneity of the Jk(null) phenotype: expression analysis of the Jk(S291P) mutation found in Finns. Blood 2000; 96:1566-1573.
28. Beckmann R, Smythe JS, Anstee DJ, Tanner MJ. Coexpression of band 3 mutants and Rh polypeptides: differential effects of band 3 on the expression of the Rh complex containing D polypeptide and the Rh complex containing CcEe polypeptide. Blood 2001; 97:2496-2505. (Pubitemid 32291498)
29. Fischer M, lttah A, Liefer I, Gorecki M. Expression and reconstitution of biologically active human acetylcholinesterase from Escherichia coll. Cell MolNeurobiol 1993; 13:25-38.
30. Velan B, Kronman C, Grosfeld H, et al. Recombinant human acetylcholinesterase is secreted from transiently transfected 293 cells as a soluble globular enzyme. Cell Moi Neurobiol 1991; 11:143-156.
31. Fouchet C, Gane P1 Huet M, et al. A study of the coregulation and tissue specificity of XG and MIC2 gene expression In eukaryotlc cells. Blood 2000; 95:1819-1826.
32. Gil MC, Lee MH, Seo JI, et al. Characterization and epitope mapping of two monoclonal antibodies against human CD99. Exp Mod Med 2002; 34:411-418. (Pubitemid 36114358)
33. Seltsam A, Grueger D, Blasczyk R, Flegel WA. Easy identification of antibodies to high-prevalence Scianna antigens and detection of admixed alloantibodies using soluble recombinant Scianna protein. Transfusion 2009 [Epub ahead of print].
34. Su YY, Gordon CT, Ye TZ, et al. Human ERMAP: an erythroid adhesion/ receptor transmembrane protein. Blood Cells Mol Dis 2001 ; 27:938-949.
35. Gubin AN, Njoroge JM, Wojda U, et al. Identification of the dombrock blood group glycoprotein as a polymorphic member of the ADP-ribosyltransferase gene family. Blood 2000; 96:2621-2627.
36. Westhoff C, Vege S, Yazdanbakhsh K, et al. A DOB allele encoding an amino acid substitution (Phe62Ser) resulting in a Dombrock null phenotype. Trans-fusion 2007; 47:1356-1362. (Pubitemid 47101065)
37. Buck TM, Skach WR. Differential stability of biogenesis Intermediates reveals a common pathway for aquaporin-1 topological maturation. J Biol Chem 2005; 280:261-269.
38. Hermand P, Gane P, Mattel MG, et al. Molecular basis and expression of the LWa/LWb blood group polymorphism. Blood 1995; 86:1590-1594.
39. Llenenklaus S, Ames RS, Tornetta MA, et al. Human anaphylatoxln C4a is a potent agonist of the guinea pig but not the human C3a receptor. J Immunol 1998; 161:2089-2093.
40. Sepp A, Dodds AW, Anderson MJ, et al. Covalent binding properties of the human complement protein C4 and hydrolysis rate of the internal thloester upon activation. Protein Sci 1993; 2:706-716.
41. Jaskiewloz E, Czerwlnskl M, Colin Y, Lisowska E. Recombinant forms of Gerbich blood group antigens: expression and purification. Transfus Clin Biol 2002; 9:121-129. (Pubitemid 34495438)
42. Sohawalder A, Reid ME, Yazdanbakhsh K. Recombinant glycophorlns C and D as tools for studying Gerbich blood group antigens. Transfusion 2004; 44:567-574. (Pubitemid 38437592)
43. Daniels GL, Green CA, Powell RM, Ward T. Hemagglutination inhibition of Cromer blood group antibodies with soluble recombinant decay-accelerating factor. Transfusion 1998; 38:332-336. (Pubitemid 28213587)
44. Telen MJ, Rao N, Udanl M, et al. Molecular mapping of the Cromer blood group Cra and Tea epitopes of decay accelerating factor: toward the use of recombinant antigens in immunohematology. Blood 1994; 84: 3205-3211.
45. Krych-Goldberg M, Hauhart RE, Subramanian VB, et al. Decay accelerating activity of complement receptor type 1 (CD35). Two active sites are required for dissociating C5 convertases. J Biol Chem 1999; 274:31160-31168.
46. Moulds JM1 Rowe KE. Neutralization of Knops system antibodies using soluble complement receptor 1. Transfusion 1996; 36:517-520.
47. Tamasauskas D, Powell V, Schawalder A, Yazdanbakhsh K. Localization of Knops system antigens in the long homologous repeats of complement receptor 1. Transfusion 2001; 41:1397-1404. (Pubitemid 33104228)
48. Dyson MR, Shadbolt SP, Vincent KJ, et al. Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression. BMC Blotechnol 2004; 4:32.
49. Yurchenko V, Pushkarsky T, Li JH, et al. Regulation of CD147 cell surface expression: Involvement of the proline residue in the CD147 transmembrane domain. J Biol Chem 2005; 280:17013-17019.
50. Tayaplwatana C, Arooncharus P, Kasinrerk W. Displaying and epitope mapping of CD147 on VCSM13 phages: influence of Escherichia coli strains. J Immunol Methods 2003; 281:177-185. (Pubitemid 37324579)
51. Seltsam A, Agaylan A, Grueger D, et al. Rapid detection of JMH antibodies with recombinant Sema7A (CD108) protein and the particle gel immunoassay. Transfusion 2008; 48:1151-1155.
52. Seltsam A, Strlgens S, Levene C. et al. The molecular diversity of Sema7A, the semaphorin that carries the JMH blood group antigens. Transfusion 2007; 47:133-146. (Pubitemid 46006321)
53. Roudler N, Baiillly P, Gane P, et al. Erythroid expression and ollgomerio state of the AQP3 protein. J Biol Chem 2002; 277:7664-7669.
54. lshlbashl K, Sasaki S, Fushlml K, et al. Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basoiateral membrane of kidney collecting duct cells. Proc Natl Acad Sci U S A 1994; 91:6269-6273.
55. Lucien N, Sidoux-Walter F, Roudier N, et al. Antigenic and functional properties of the human red blood cell urea transporter hUT-B1. J Biol Chem 2002; 277:34101-34108. (Pubitemid 35056229)
56. Figueiredo C, Seltsam A, Blasczyk R. Class-, gene-, and group-specific HLA silencing by lentlviral shRNA delivery. J Mol Med 2006; 84:425-437. (Pubitemid 43673617)
57. Smith JD, Hamour IM, Banner NR, Rose ML. C4d fixing, lumlnex binding antibodies: a new tool for prediction of graft failure after heart transplantation. Am J Transplant 2007; 7:2809-2815.
58. Brecher M. AABB Technical Manual. 15th ed. Bethesda: AABB Press; 2005
59. Middleton J, Crookston MC. Chido-substance in plasma. Vox Sang 1972; 23:256-261.
60. Daniels G. Human blood groups. Oxford, United Kingdom: Blackwell Scientific Publications; 2002.
61. Seltsam A, Agaylan A, Grueger D, et al. Rapid detection of antl-Lu(b) with recombinant Lu(b) protein and the particle gel immunoassay. Transfusion 2008;48:731-734.
62. The serious hazards of transfusion (SHOT) steering group. Annual report 2005 [monograph on the Internet]. Manchester: SHOT Office 2005. http://www.shotuk.org
63. Meyer O, Salama A, Pittet N, Schwind P. Rapid detection of heparln-lnduced platelet antibodies with particle gel immunoassay (ID-HPF4). Lancet 1999; 354:1525-1526. (Pubitemid 29502110)
64. Seltsam A, Wagner FF, Salama A, Flegel WA. Antibodies to high-frequency antigens may decrease the quality of transfusion support: an observational study. Transfusion 2003; 43:1563-1566. (Pubitemid 37371827)
65. Heuft HG, Genth R, Wittmann G, Salama A. Alloantibodies directed against high-frequency red blood cell antigens. InfusionstherTransfusionsmed 1999; 26:234-239. (Pubitemid 29369948)
66. Grubb R. Correlation between Lewis blood group and secretor character In man. Nature 1948; 162:933.
67. Morton JA, Pickles MM, Terry AM. The Sda blood group antigen in tissues and body fluids. Vox Sang 1970; 19:472-482.
68. Dzierzkowa-Borodej W, Seyfried H, Nichols M, et al. The recognition of water-soluble I blood group substance. Vox Sang 1970; 18:222-234.