Phytochemical characterization of an adaptogenic preparation from Rhodiola heterodonta

Natural Product Communications

Volumn 4, Issue 8, 2009, Pages 1053-1058

  Grace, Mary H ^a   Yousef, Gad G ^a   Kurmukov, Anvar G ^b   Raskin, Ilya ^c   Lila, Mary Ann ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b Ministry of Health Uzbekistan   (Uzbekistan)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

Adaptogenic activity; Anti hypoxia; HPLC ESI MS; Phenylethanoid; Proanthocyanidin; Rhodiola heterodonta

Indexed keywords

3 O GALLOYL EPIGALLOCATECHIN 3 O GALLATE; EPIGALLOCATECHIN EPIGALLOCATECHIN 3 O GALLATE; EPIGALLOCATECHIN GALLATE; HETERODONTOSIDE; MONGRHOSIDE; RHODIOCYANOSIDE A; RHODIOLA EXTRACT; SALIDROSIDE; TYROSOL; TYROSOL METHYL ETHER; UNCLASSIFIED DRUG; VIRIDOSIDE; 4-HYDROXYPHENYLETHANOL; ALCOHOL; CATECHIN; DRUG DERIVATIVE; GALLOCATECHIN; GLUCOSIDE; PHENETHYL ALCOHOL; PHENOL DERIVATIVE; PLANT MEDICINAL PRODUCT; PROANTHOCYANIDIN;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL COMPOSITION; COLUMN CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOXIA; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PHYTOCHEMISTRY; RHODIOLA; RHODIOLA HETERODONTA; SURVIVAL TIME; ANIMAL; ANOXIA; CHEMISTRY; GEL CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METHODOLOGY;

MUS; RHODIOLA HETERODONTA;

ANIMALS; ANOXIA; CATECHIN; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; ETHANOL; GLUCOSIDES; MASS SPECTROMETRY; MICE; PHENOLS; PHENYLETHYL ALCOHOL; PLANT PREPARATIONS; PROANTHOCYANIDINS; RHODIOLA;

EID: 73949106585     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x0900400807     Document Type: Article

References (28)

1. Brown RP, Gerbarg PL, Ramazanov Z. (2002) Rhodiola rosea. A phytomedicinal overview. Herbal Gram, 56, 40-52.
2. Kelly GS. (2001) Rhodiola rosea: A possible plant adaptogen. Alternative Medicine Review, 6, 293-302.
3. Khanum F, Bawa AS, Singh B. (2005) Rhodiola rosea: A versatile adaptogen. Comprehensive Reviews in Food Science and Food Safety, 4, 55-62.
4. Lazarev NV. (1962) Actual problems of the studies of the action of adaptogens, particularly preparations of Eleuterococcus. Symposium on Ginseng and Eleuterococcus. In: XX meeting on investigations of Ginseng and other medicinal plants of Far East, DVFSO, Vladivostok, pp 7-14.
5. Perfumi M, Mattioli L. (2007) Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice. Phytotherapy Research, 21, 37-43. (Pubitemid 46173906)
6. Panossian A, Wikman G, Wagner H. (1999) Plant adaptogens. Part 3. Earlier and more recent aspects and concepts on their mode of action. Phytomedicine, 6, 287-300. (Pubitemid 129633202)
7. Panossian A. (2003) Adaptogens: Tonic herbs for fatigue and stress. Alternative and Complementary Therapies, 9, 327-331.
8. Panossian A, Wagner H. (2005) Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration. Phytotherapy Research, 19, 819-838. (Pubitemid 41670526)
9. Wagner H, Noerr H, Winterhoff H. (1994) Plant adaptogens. Phytomedicine, 1, 63-76.
10. Singh B, Saxena AK, Chandan BK, Gupta DK, Bhutani KK, Anand KK. (2001) Adaptogenic activity of a novel, withanolide free aqueous fraction from the roots of Withania somnifera. Phytotherapy Research, 15, 311-318. (Pubitemid 32613099)
11. Grover SK, Divekar HM, Kumar R, Pahwa ML, Bhardwaj SK, Gupta AK, Srivastava KK. (1995) Experimental evaluation of a composite Indian herbal preparation II (CIHP) as an adaptogen and its mechanism of action. Pharmaceutical Biology (formerly International Journal of Pharmacognosy), 33, 148-154.
12. Bakibaev AA, Gorshkova VK, Saratikov AS. (1997) Antihypoxic properties of organic compounds (A review). Pharmaceutical Chemistry Journal, 31, 3-16.
13. Li H, Chen F. (2001) Preparative isolation and purification of salidroside from the Chinese medicinal plant Rhodiola sachalinensis by high-speed counter-current chromatography. Journal of Chromatography A, 932, 91-95. (Pubitemid 32938190)
14. Ohsugi M, Fan W, Hase K, Xiong Q, Tezuka Y, Komatsu K, Namba T, Saitoh T, Tazawa K, Kadota S. (1999) Active-oxygen scavenging activity of traditional nourishing-tonic herbal medicines and active constituents of Rhodiola sacra. Journal of Ethnopharmacology, 67, 111-119. (Pubitemid 29389750)
15. Yousef GG, Grace MH, Cheng DM, Belolipov IV, Raskin I, Lila MA. (2006) Comparative phytochemical characterization of three Rhodiola species. Phytochemistry, 67, 2380-2391. (Pubitemid 44527929)
16. Chen Z, Chen Y, Wang D. (2006) Determination of the content of salidroside in different Rhodiola varieties by HPLC. Zhongguo Zhongyao Zazhi, 31, 939-941.
17. Hu H, Yang L, Hu H, Li J. (2007) Determination of salidroside in Rhodiola L from different districts. Henan Yixue Yanjiu, 16, 203-204.
18. Mao Y, Li Y, Yao N. (2007) Simultaneous determination of salidroside and tyrosol in extracts of Rhodiola L. by microwave assisted extraction and high-performance liquid chromatography. Journal of Pharmceutical and Biomedical Analysis, 45, 510-515. (Pubitemid 47588760)
19. Meng J, Wang S, Han F, Li S. (2006) Determination of salidroside and p-tyrosol in Rhodiola for injection by SPE-HPLC. Zhongguo Zhongyao Zazhi, 31, 119-121.
20. Zhang J, Chen X, Gao G, Bi K. (2006) Simultaneous HPLC determination of salidroside and tyrosol in Rhodiola crenulata. Yaowu Fenxi Zazhi, 26, 1238-1240.
21. Kurmukov AG, Aizikov MI, Rakhimov SS. (1986) Pharmacology of the plant polyphenol epigalokhin. Farmakol Toksikol, 49, 45-48.
22. Chen Z, Lu Y, Wang Z, Tao X, Wei D. (2007) Protective effects of salidroside on hypoxic/reoxygenation injury by sodium hyposulfite in PC12 cells. Pharmaceutical Biology, 45, 604-612. (Pubitemid 47493777)
23. Ganzera M, Yala Y, Khan IA. (2001) Analysis of marker compounds of Rhodiola rosea L. (golden root) by reversed phase high performance liquid chromatography. Chemical and Pharmaceutical Bulletin, 49, 465-467. (Pubitemid 32367681)
24. Wiedenfeld H, Dumaa M, Malinowski M, Furmanowa M, Narantuya S. (2007) Phytochemical and analytical studies of extracts from Rhodiola rosea and Rhodiola quadrifida. Pharmazie, 62, 308-311. (Pubitemid 46596379)
25. Zulfiqar A, Fronczek FR, Khan IA. (2008) Phenylalkanoids and monoterpene analogues from the roots of Rhodiola rosea. Planta Medica, 74, 178-181.
26. Nonaka GI, Muta M, Myricatin IN. (1983) Myricatin, a galloyl flavanonol sulfate, and prodelphinidin gallates from Myrica rubra. Phytochemistry, 22, 237-241.
27. Linh PT, Kim, YH, Hong SP, Jian JJ, Kang JS. (2000) Quantitative determination of salidroside and tyrosol from the underground part of Rhodiola rosea by high performance liquid chromatography. Archives of Pharmacal Research, 23, 349-352.
28. Kurmukov AG, Aizikov MI, Nazrullaev SS, Aripova SF, Tolstikova OV, Abdilalimov O. (1993) Antihypoxic activity of the alkaloid dipthocarpaine and its synthetic analogs. Pharmaceutical Chemistry Journal, 27, 176-178.