Fatty acid-spermine conjugates as DNA carriers for nonviral in vivo gene delivery

Gene Therapy

Volumn 16, Issue 12, 2009, Pages 1429-1440

  Viola, J R ^a   Leijonmarck, H ^b   Simonson, O E ^a   Oprea, I I ^a   Frithiof, R ^b   Purhonen, P ^b   Moreno, P M D ^a   Lundin, K E ^a   Stromberg R ^b   Smith, C I E ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

In vivo gene delivery; Lipospermines; Non viral gene delivery

Indexed keywords

ACETYLSPERMINE; BUTANOYLSPERMINE; DECANOYLSPERMINE; DEOXYRIBONUCLEASE I; HYDROCARBON; LINOLEOYLSPERMINE; LINOLYLSPERMINE; NANOPARTICLE; OLEYLSPERMINE; PALMITOYLSPERMINE; PLASMID DNA; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; ENZYME DEGRADATION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIGHT SCATTERING; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PLASMID; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN INTERACTION; TOXICITY TESTING;

ANIMALS; DNA; FATTY ACIDS; FATTY ACIDS, UNSATURATED; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEP G2 CELLS; HUMANS; MICE; PLASMIDS; SPERMINE;

EID: 73849083445     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2009.108     Document Type: Article

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