Effects of resistance training combined with antioxidant supplementation on fat-free mass and insulin sensitivity in healthy elderly subjects

Diabetes Research and Clinical Practice

Volumn 87, Issue 1, 2010, Pages e1-

  Bobeuf, Florian ^a,b   Labonté, Mélissa ^a   Khalil, Abdelouahed ^a,b   Dionne, Isabelle J ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Fat free mass; Insulin sensitivity; Resistance exercise

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; PLACEBO;

AGED; ARTICLE; BODY COMPOSITION; BODY FAT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; EXERCISE; FEMALE; HUMAN; HUMAN EXPERIMENT; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NORMAL HUMAN; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIAL;

EID: 73749087343     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2009.10.001     Document Type: Article

References (15)

1. Moore D.R., Del Bel N.C., Nizi K.I., Hartman J.W., Tang J.E., Armstrong D., et al. Resistance training reduces fasted- and fed-state leucine turnover and increases dietary nitrogen retention in previously untrained young men. J. Nutr. 137 (2007) 985-991
2. Wright D., and Sutherland L. Antioxidant supplemention in the treatment of skeletal muscle insulin resistance: potential mechanisms and clinical relevance. Appl. Physiol. Nutr. Metab. 33 (2008) 21-31
3. Dionne I.J., Melancon M.O., Brochu M., Ades P.A., and Poelhman E.T. Age-related differences in metabolic adaptations following resistance training in women. Exp. Gerontol. 39 (2004) 133-138
4. Toth M.J., Beckett T., and Poehlman E.T. Physical activity and the progressive change in body composition with aging: current evidence and research issues. Med. Sci. Sports Exerc. 31 (1999) S590-S596
5. Rudich A., Kozlovsky N., Potashnik R., and Bashan N. Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes. Am. J. Physiol. 272 (1997) E935-E940
6. Paolisso G., D'Amore A., Di Maro G., Galzerano D., Tesauro P., Varricchio M., et al. Evidence for a relationship between free radicals and insulin action in the elderly. Metabolism 42 (1993) 659-663
7. Paolisso G., D'Amore A., Balbi V., Volpe C., Galzerano D., Giugliano D., et al. Plasma vitamin C affects glucose homeostasis in healthy subjects and in non-insulin-dependent diabetics. Am. J. Physiol. 266 (1994) E261-E268
8. Dela F., and Kjaer M. Resistance training, insulin sensitivity and muscle function in the elderly. Essays Biochem. 42 (2006) 75-88
9. Pereira L.O., and Lancha Jr. A.H. Effect of insulin and contraction up on glucose transport in skeletal muscle. Prog. Biophys. Mol. Biol. 84 (2004) 1-27
10. Ceriello A. Oxidative stress and glycemic regulation. Metabolism 49 (2000) 27-29
11. Paolisso G., D'Amore A., Giugliano D., Ceriello A., Varricchio M., and D'Onofrio F. Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetic patients. Am. J. Clin. Nutr. 57 (1993) 650-656
12. Karakelides H., and Nair K.S. Sarcopenia of aging and its metabolic impact. Curr. Top. Dev. Biol. 68 (2005) 123-148
13. Goldfarb A.H., McKenzie M.J., and Bloomer R.J. Gender comparisons of exercise-induced oxidative stress: influence of antioxidant supplementation. Appl. Physiol. Nutr. Metab. 32 (2007) 1124-1131
14. Labonté M., Bobeuf F., Bouchard D.R., Sénéchal M., Tessier D., Khalil A., et al. Effects of antioxidant supplements combined with resistance exercise on gains in fat-free mass in healthy elderly subjects: a pilot study. J. Am. Geriatr. Soc. 56 (2008) 1766-1768
15. Ji L.L. Exercise at old age: does it increase or alleviate oxidative stress?. Ann. N. Y. Acad. Sci. 928 (2001) 236-247