Clinical features and prognosis of late-onset systemic lupus erythematosus: Results from the 1000 faces of lupus study

Journal of Rheumatology

Volumn 37, Issue 1, 2010, Pages 38-44

  Lalani, Sheliza ^a   Pope, Janet ^a   De Leon, Faye ^b   Peschken, Christine ^c  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

1000 Canadian faces of lupus; Age of onset; Elder onset; Severity; Systemic lupus erythematosus

Indexed keywords

AUTOANTIBODY; AZATHIOPRINE; CYCLOPHOSPHAMIDE; DOUBLE STRANDED DNA ANTIBODY; HYDROXYCHLOROQUINE; LUPUS ANTICOAGULANT; METHOTREXATE; MYCOPHENOLIC ACID; PREDNISONE; RIBONUCLEOPROTEIN; RITUXIMAB; SM ANTIBODY;

ADULT; AGED; ALOPECIA; ARTHRALGIA; ARTHRITIS; ARTICLE; ASIAN; CAUCASIAN; CLINICAL FEATURE; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CYTOPENIA; DISEASE ACTIVITY; DISEASE DURATION; FATIGUE; FEMALE; FEVER; FIBROMYALGIA; GROUPS BY AGE; HEMOLYTIC ANEMIA; HUMAN; HYPOCOMPLEMENTEMIA; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MALE; MOUTH ULCER; MYOSITIS; NEGRO; NEPHRITIS; NEPHROTIC SYNDROME; NOSE ULCER; ONSET AGE; PERICARDITIS; PHOTOSENSITIVITY; PLASMAPHERESIS; PLEURA EFFUSION; PLEURISY; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEINURIA; PSYCHOSIS; RASH; RAYNAUD PHENOMENON; SEIZURE; SJOEGREN SYNDROME; SURVIVAL; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA; VENEREAL DISEASE REACTION TEST; WEIGHT REDUCTION;

ADOLESCENT; ADULT; AGE FACTORS; AGE OF ONSET; AGED; AGED, 80 AND OVER; ANTIRHEUMATIC AGENTS; CANADA; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; FEMALE; HUMANS; INFANT; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; PROGNOSIS; YOUNG ADULT;

EID: 73649135712     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: 10.3899/jrheum.080957     Document Type: Article

References (34)

1. Rovensky J, Tuchynova A. Systemic lupus erythematosus in the elderly. National Institute of Rheumatic Diseases. Slovak Republic. Autoimmun Rev 2008;7:235-9.
2. Font J, Pallarés L, Cervera R, López-Soto A, Navarro M, Bosch X, et al. Systemic lupus erythematosus in the elderly: clinical and immunological characteristics. Ann Rheum Dis 1991;50:702-5.
3. Mak SK, Lam EKM, Wong AKM. Clinical profile of patients with late-onset SLE: not a benign subgroup. Lupus 1998;7:23-8.
4. Formiga F, Moga I, Pac M, Mitjavila F, Rivera A, Pujol R. Mild presentation of systemic lupus erythematosus in elderly patients assessed by SLEDAI. Lupus 1999;8:462-5.
5. Boddaert J, Huong du LT, Amoura Z, Wechsler B, Godeau P, Piette JC. Late-onset systemic lupus erythematosus: a personal series of 47 patients and pooled analysis of 714 cases in the literature. Medicine 2004;83:348-59.
6. Ward M, Polisson R. A meta-analysis of the clinical manifestations of older-onset systemic lupus erythematosus. Arthritis Rheum 2005;32:1226-32.
7. Bertoli AM, Alarcón GS, Calvo-Alén J, Fernández M, Vilá LM, Reveille JD; LUMINA Study Group. Systemic lupus erythematosus in a multiethnic US cohort. XXXIII. Clinical (corrected) features, course and outcome in patients with late-onset disease. Arthritis Rheum 2006;54:1580-7.
8. Maddison P, Farewell V, Isenberg D, Aranow C, Bae SC, Barr S, et al. The rate and pattern of organ damage in late onset systemic lupus erythematosus. J Rheumatol 2002;29:913-7.
9. Shaikh SK, Wang F. Late-onset systemic lupus erythematosus: clinical and immunological characteristics. Med J Malaysia 1995;50:25-31.
10. Ho CT, Mok CC, Lau CS, Wong RW. Late onset lupus erythematosus in southern Chinese. Ann Rheum Dis 1998;57:437-40.
11. Pu SJ, Luo SF, Wu YJ, Cheng HS, Ho HH. The clinical features and prognosis of lupus with disease onset at age 65 and older. Lupus 2000;9:96-100.
12. Padovan M, Govoni M, Castellino G, Rizzo N, Fotinidi M, Trotta F. Late onset systemic lupus erythematosus: no substantial differences using different cut off ages. Rheumatol Int 2007;27:735-41.
13. Lazaro D. Elderly-onset systemic lupus erythematosus: prevalence, clinical course and treatment. Drugs Aging 2007;24:701-15.
14. Karoubi Nordon E, Hayem G, Mentres F, Palazzo E, Legrain S, Meyer O, et al. Late onset systemic lupus erythematosus: a new approach. Lupus 2007;16:1011-4.
15. Appenzeller S, Pereira DA, Costallat LT. Greater accrual damage in late-onset systemic lupus erythematosus: a long-term follow-up study. Lupus 2008;17:1023-8.
16. Takayasu V, Bonfá E, Levy Neto M, Kumeda C, Daud RM, Cossermelli W. Renal damage in systemic lupus erythematosus: a comparative analysis of different age groups. Lupus 2007;16:28-34. Erratum in: Lupus 2007;16:149.
17. Wang J, Yang S, Chen JJ, Zhou SM, He SM, Liang YH, et al. Systemic lupus erythematosus: a genetic epidemiology study of 695 patients from China. Arch Dermatol Res 2007;298:485-91.
18. Sayarlioglu M, Cefle A, Kamali S, Gul A, Inanc M, Ocal L, et al. Characteristics of patients with late onset systemic lupus erythematosus in Turkey. Int J Clin Pract 2005;59:183-7.
19. Antolin J, Amerigo MJ, Cantabrana A, Roces A, Jimenez P. Systemic lupus erythematosus: clinical manifestations and immunological parameters in 194 patients. Subgroup classification of SLE. Clin Rheumatol 1995;14:678-85.
20. Koh ET, Boey ML. Late onset lupus: a clinical and immunological study in a predominantly Chinese population. J Rheumatol 1994;21:1463-7.
21. Takayasu V, Bonfá E, Levy Neto M, Kumeda C, Daud RM, Cossermelli W. Systemic lupus erythematosus in the aged: clinical and laboratory characteristics. Rev Hosp Clin Fac Med Sao Paulo 1992;47:6-9.
22. Liu HW, Lin SF, Chen JR, Chuang WL, Yen JH, Tsai JH. Subset of systemic lupus erythematosus with late onset. Gaoxiong Yi Xue Ke Xue Za Zhi 1988;4:547-52.
23. McDonald K, Hutchinson M, Bresnihan B. The frequent occurrence of neurological disease in patients with late-onset systemic lupus erythematosus. Br J Rheumatol 1984;23:186-9.
24. Pahissa A, Martí S, Martínez-Vázquez JM, Guardia J. Systemic lupus erythematosus with late clinical onset [author's translation]. Med Clin (Barc) 1981;76:299-302.
25. Baker SB, Rovira JR, Campion EW, Mills JA. Late onset systemic lupus erythematosus. Am J Med 1979;66:727-32.
26. Costallat LT, Coimbra AM. Systemic lupus erythematosus: clinical and laboratory aspect related to age at disease onset. Clin Exp Rheumatol 1994;12:603-7.
27. Joseph RR, Zarafonetis CJD. Clinical onset of lupus erythematosus in the older age group. J Am Geriatr Soc 1964;12:787-99.
28. Ballou SP, Khan MA, Kushner I. Clinical features of systemic lupus erythematosus: differences related to race and age of onset. Arthritis Rheum 1982;25:55-60.
29. Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P, et al. Systemic lupus erythematosus: clinical and immunologic patterns of disease expression in a cohort of 1,000 patients. The European Working Party on systemic lupus erythematosus. Medicine (Baltimore) 1993;72:113-24.
30. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NM, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
31. Liang MH, Socher SA, Larson MG, Schur PH. Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus. Arthritis Rheum 1989;32:1107-18.
32. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH. Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum 1992;35:630-40.
33. Gladman D, Ginzler E, Goldsmith C, Fortin P, Liang M, Urowitz M, et al. The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus. Arthritis Rheum 1996;39:363-9.
34. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-83.