Quantitative detection of the active "spice" ingredient JWH-018 in serum by means of liquid chromatography-tandem mass spectrometry;Quantitativer nachweis des "spice"-wirkstoffes JWH-018 im serum mittels flüssigchromatographie-tandemmassenspektrometrie

Blutalkohol

Volumn 46, Issue 6, 2009, Pages 373-379

  Neukamm, Merja A ^a   Mürdter, Thomas E ^b   Knabbe, Cornelius ^a   Wehner, Heinz Dieter ^a,b   Wehner, Frank ^b  

^a ROBERT BOSCH HOSPITAL   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Blood test evidence; Inducement; JWH 018; LC MS MS; Spice

Indexed keywords

3 (1 NAPHTHOYL) 1 PENTYLINDOLE; CANNABINOID DERIVATIVE; UNCLASSIFIED DRUG;

HUMAN; LIQUID CHROMATOGRAPHY; REVIEW; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 73649126556     PISSN: 00065250     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (9)

1. Auwärter V, Dresen S, Weinmann W, Ferreirós N (2008) "SPICE" sowie weitere Räuchermischungen enthalten Designer-Cannabinoid. Toxichem und Krimtech 75 (3): 127-129
2. Bundesamt für Risikobewertung, Stellungnahme Nr. 045/2008 vom 24. November 2008
3. Bundesgesetzblatt (2009) Zweiundzwanzigste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften vom 19. Januar 2009, Teil I Nr. 3: 49-50
4. www.mahsan.de NewsForum Februar 2009
5. Huffman J W, Szklennik P V, Almond A, Bushell K, Selley D E, He H, Cassidy M P, Wiley J L, Martin B R (2005) 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett 15: 4110-4113 (Pubitemid 41132671)
6. Wiley J L, Compton D R, Dai D, Lainton J A, Phillips M, Huffman J W, Martin B R (1998) Structure-activity relationships of indole- and pyrrole-derived cannabinoids. J Pharmacol Exp Ther 285: 995-1004 (Pubitemid 28277896)
7. Melvin L S, Milne G M, Johnson M R, Subramaniam B, Wilken G H, Howlett A C (1993): Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs. Mol Pharmacol 44: 1008-1015 (Pubitemid 23344968)
8. Barnett G, Licko V, Thompson T (1985) Behavioral pharmacokinetics of marijuana. Psychopharmacol 85: 51-56
9. Huestis M A, Henningfield J E, Cone E J (1992) Blood cannabinoides I; Absorption of THC and formation of 11-OH-THC and THC-COOH during and after smoking marijuana. J Anal Toxicol 34: 276-282