메뉴 건너뛰기




Volumn 8, Issue 9, 2009, Pages

Negative outcomes associated with adding anti-epidermal growth factor receptor (EGFR) monoclonal antibodies to chemotherapybevacizumab combination therapy in patients with metastatic colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CAPECITABINE; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; FLUOROURACIL; FOLINIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRINOTECAN; MONOCLONAL ANTIBODY; OXALIPLATIN; PANITUMUMAB; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 73649103125     PISSN: 15429520     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note
Times cited : (1)

References (30)
  • 1
    • 42949106166 scopus 로고    scopus 로고
    • Monoclonal antibodies in cancer therapy: 25 years of progress
    • Oldham RK, Dillman RO. Monoclonal antibodies in cancer therapy: 25 years of progress. J Clin Oncol. 2008;26:1774-1777.
    • (2008) J Clin Oncol , vol.26 , pp. 1774-1777
    • Oldham, R.K.1    Dillman, R.O.2
  • 2
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F, Hurwitz HI, Fehrenbacher L, et al. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol. 2003;21:60-65.
    • (2003) J Clin Oncol , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3
  • 3
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 4
    • 20644432867 scopus 로고    scopus 로고
    • Bevacizumab in combination with fluorouracil and leucovorin: An active regimen for first-line metastatic colorectal cancer
    • Hurwitz HI, Fehrenbacher L, Hainsworth JD, et al. Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer. J Clin Oncol. 2005;23:3502-3508.
    • (2005) J Clin Oncol , vol.23 , pp. 3502-3508
    • Hurwitz, H.I.1    Fehrenbacher, L.2    Hainsworth, J.D.3
  • 5
    • 20544478429 scopus 로고    scopus 로고
    • Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
    • Kabbinavar FF, Schulz J, McCleod M, et al. Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. J Clin Oncol. 2005;23:3697-3705.
    • (2005) J Clin Oncol , vol.23 , pp. 3697-3705
    • Kabbinavar, F.F.1    Schulz, J.2    McCleod, M.3
  • 6
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio BJ, Catalano PJ, Meropol NJ, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol. 2007;25:1539-1544.
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3
  • 7
    • 20544471876 scopus 로고    scopus 로고
    • Combined analysis of effi cacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
    • Kabbinavar FF, Hambleton J, Mass RD, et al. Combined analysis of effi cacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol. 2005;23:3706-3712.
    • (2005) J Clin Oncol , vol.23 , pp. 3706-3712
    • Kabbinavar, F.F.1    Hambleton, J.2    Mass, R.D.3
  • 8
    • 33748752619 scopus 로고    scopus 로고
    • A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group study E2200
    • Giantonio BJ, Levy DE, O'Dwyer PJ, et al. A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200. Ann Oncol. 2006;17:1399-1403.
    • (2006) Ann Oncol , vol.17 , pp. 1399-1403
    • Giantonio, B.J.1    Levy, D.E.2    O'Dwyer, P.J.3
  • 9
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med. 2004;351:337-345.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 10
    • 33750615769 scopus 로고    scopus 로고
    • Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines
    • Lenz HJ, Van Cutsem E, Khambata-Ford S, et al. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol. 2006;24:4914-4921.
    • (2006) J Clin Oncol , vol.24 , pp. 4914-4921
    • Lenz, H.J.1    Van Cutsem, E.2    Khambata-Ford, S.3
  • 11
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • Saltz LB, Meropol NJ, Loehrer PJ Sr, et al. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol. 2004;22:1201-1208.
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr, P.J.3
  • 12
    • 34247480064 scopus 로고    scopus 로고
    • Panitumumab with irinotecan/leucovorin/5-fluorouracil for fi rst-line treatment of metastatic colorectal cancer
    • Berlin J, Posey J, Tchekmedyian S, et al. Panitumumab with irinotecan/leucovorin/5-fluorouracil for fi rst-line treatment of metastatic colorectal cancer. Clin Colorectal Cancer. 2007;6:427-432.
    • (2007) Clin Colorectal Cancer , vol.6 , pp. 427-432
    • Berlin, J.1    Posey, J.2    Tchekmedyian, S.3
  • 13
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
    • Van Cutsem E, Peeters M, Siena S, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol. 2007;25:1658-1664.
    • (2007) J Clin Oncol , vol.25 , pp. 1658-1664
    • Van Cutsem, E.1    Peeters, M.2    Siena, S.3
  • 14
    • 34548289390 scopus 로고    scopus 로고
    • FDA drug approval summary: Panitumumab (Vectibix)
    • Giusti RM, Shastri KA, Cohen MH, et al. FDA drug approval summary: panitumumab (Vectibix). Oncologist. 2007;12:577-583.
    • (2007) Oncologist , vol.12 , pp. 577-583
    • Giusti, R.M.1    Shastri, K.A.2    Cohen, M.H.3
  • 15
    • 0022454841 scopus 로고
    • Preclinical trials with combinations and conjugates of T101 monoclonal antibody and doxorubicin
    • Dillman RO, Shawler DL, Johnson DE, et al. Preclinical trials with combinations and conjugates of T101 monoclonal antibody and doxorubicin. Cancer Res. 1986;46:4886 4891.
    • (1986) Cancer Res , vol.46 , pp. 4886-4891
    • Dillman, R.O.1    Shawler, D.L.2    Johnson, D.E.3
  • 16
    • 0024313659 scopus 로고
    • Monoclonal antibodies for treating cancer
    • Dillman RO. Monoclonal antibodies for treating cancer. Ann Intern Med. 1989;111:592 603.
    • (1989) Ann Intern Med , vol.111 , pp. 592-603
    • Dillman, R.O.1
  • 17
    • 0028291649 scopus 로고
    • Antibodies as cytotoxic therapy
    • Dillman RO. Antibodies as cytotoxic therapy. J Clin Oncol. 1994;12:1497-1515.
    • (1994) J Clin Oncol , vol.12 , pp. 1497-1515
    • Dillman, R.O.1
  • 18
    • 0035217994 scopus 로고    scopus 로고
    • Monoclonal antibodies in the treatment of malignancy: Basic concepts and recent developments
    • Dillman RO. Monoclonal antibodies in the treatment of malignancy: basic concepts and recent developments. Cancer Invest. 2001;19:833-841.
    • (2001) Cancer Invest , vol.19 , pp. 833-841
    • Dillman, R.O.1
  • 19
    • 0023781775 scopus 로고
    • Superiority of an acid labile daunorubicin monoclonal antibody immunoconjugate compared to free drug
    • Dillman RO, Johnson DE, Shawler DL, et al. Superiority of an acid labile daunorubicin monoclonal antibody immunoconjugate compared to free drug. Cancer Res. 1988;48:6097 6102.
    • (1988) Cancer Res , vol.48 , pp. 6097-6102
    • Dillman, R.O.1    Johnson, D.E.2    Shawler, D.L.3
  • 20
    • 0024834765 scopus 로고
    • Significance of antigen, drug, and tumor cell targets in the preclinical evaluation of doxorubicin, daunorubicin, methotrexate, and mitomycin-C monoclonal antibody immunoconjugates
    • Dillman RO, Johnson DE, Ogden J, et al. Significance of antigen, drug, and tumor cell targets in the preclinical evaluation of doxorubicin, daunorubicin, methotrexate, and mitomycin-C monoclonal antibody immunoconjugates. Mol Biother. 1989;1:250-255.
    • (1989) Mol Biother , vol.1 , pp. 250-255
    • Dillman, R.O.1    Johnson, D.E.2    Ogden, J.3
  • 21
    • 63449094781 scopus 로고    scopus 로고
    • K-ras mutations in colorectal cancer: A practice changing discovery
    • Saif MW, Shah M. K-ras mutations in colorectal cancer: a practice changing discovery. Clin Adv Hematol Oncol. 2009;7:45-53.
    • (2009) Clin Adv Hematol Oncol , vol.7 , pp. 45-53
    • Saif, M.W.1    Shah, M.2
  • 22
    • 0020350960 scopus 로고
    • Intratumor immunologic heterogeneity
    • Miller FR. Intratumor immunologic heterogeneity. Cancer Metastasis Rev. 1982;1:319-334.
    • (1982) Cancer Metastasis Rev , vol.1 , pp. 319-334
    • Miller, F.R.1
  • 23
    • 17944370631 scopus 로고    scopus 로고
    • Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors
    • Shaheen RM, Ahmad SA, Liu W, et al. Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors. Br J Cancer. 2001;85: 584-589.
    • (2001) Br J Cancer , vol.85 , pp. 584-589
    • Shaheen, R.M.1    Ahmad, S.A.2    Liu, W.3
  • 24
    • 33646227448 scopus 로고    scopus 로고
    • Synergistic antitumor effects of combined epidermal growth factor receptor and vascular endothelial growth factor receptor-2 targeted therapy
    • Tonra JR, Deevi DS, Corcoran E, et al. Synergistic antitumor effects of combined epidermal growth factor receptor and vascular endothelial growth factor receptor-2 targeted therapy. Clin Cancer Res. 2006;12:2197-2207.
    • (2006) Clin Cancer Res , vol.12 , pp. 2197-2207
    • Tonra, J.R.1    Deevi, D.S.2    Corcoran, E.3
  • 25
    • 34147131736 scopus 로고    scopus 로고
    • Dual targeting of the vascular endothelial growth factor and epidermal growth factor receptor pathways: Rationale and clinical applications for non-small-cell lung cancer
    • Byers LA, Heymach JV. Dual targeting of the vascular endothelial growth factor and epidermal growth factor receptor pathways: rationale and clinical applications for non-small-cell lung cancer. Clin Lung Cancer. 2007;8(suppl 2):S79-S85.
    • (2007) Clin Lung Cancer , vol.8 , Issue.SUPPL. 2
    • Byers, L.A.1    Heymach, J.V.2
  • 26
    • 35648941728 scopus 로고    scopus 로고
    • Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: The BOND-2 study
    • Saltz LB, Lenz HJ, Kindler HL, et al. Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: the BOND-2 study. J Clin Oncol. 2007;25:4557-4561.
    • (2007) J Clin Oncol , vol.25 , pp. 4557-4561
    • Saltz, L.B.1    Lenz, H.J.2    Kindler, H.L.3
  • 27
    • 59749091477 scopus 로고    scopus 로고
    • Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
    • Tol J, Koopman M, Cats A, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med. 2009;360:563-572.
    • (2009) N Engl J Med , vol.360 , pp. 563-572
    • Tol, J.1    Koopman, M.2    Cats, A.3
  • 28
    • 59749089432 scopus 로고    scopus 로고
    • Targeted therapy for advanced colorectal cancer-more is not always better
    • Mayer RJ. Targeted therapy for advanced colorectal cancer-more is not always better. N Engl J Med. 2009;360:623-625.
    • (2009) N Engl J Med , vol.360 , pp. 623-625
    • Mayer, R.J.1
  • 29
    • 59949102930 scopus 로고    scopus 로고
    • A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
    • Hecht JR, Mitchell E, Chidiac T, et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol. 2009;27:672-680.
    • (2009) J Clin Oncol , vol.27 , pp. 672-680
    • Hecht, J.R.1    Mitchell, E.2    Chidiac, T.3
  • 30
    • 59949090762 scopus 로고    scopus 로고
    • Dual-antibody therapy in advanced colorectal cancer: Gather ye rosebuds while ye may
    • Blanke CD. Dual-antibody therapy in advanced colorectal cancer: gather ye rosebuds while ye may. J Clin Oncol. 2009;27: 655-658.
    • (2009) J Clin Oncol , vol.27 , pp. 655-658
    • Blanke, C.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.