Pioglitazone reduces tumor necrosis factor-α serum concentration and mRNA expression of adipose tissue in hypercholesterolemic rabbits

International Journal of Cardiology

Volumn 138, Issue 2, 2010, Pages 151-156

  Wu, Zhi hong ^a   Zhao, Shui ping ^a   Chu, Luo xiang ^a   Ye, Hui jun ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Adipocyte; Hypercholesterolemia; Pioglitazone; Tumor necrosis factor

Indexed keywords

CHOLESTEROL; GLUCOSE; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PIOGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL RABBIT; GLUCOSE BLOOD LEVEL; HYPERCHOLESTEROLEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

ADIPOCYTES; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CELLS, CULTURED; CHOLESTEROL, DIETARY; CHOLESTEROL, LDL; GENE EXPRESSION; HYPERCHOLESTEROLEMIA; HYPOGLYCEMIC AGENTS; LIPOPOLYSACCHARIDES; MALE; RABBITS; RNA, MESSENGER; SUBCUTANEOUS FAT; THIAZOLIDINEDIONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 73649099213     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2008.08.009     Document Type: Article

References (28)

1. Libby P., Ridker P.M., and Maseri A. Inflammation and atherosclerosis. Circulation 105 (2002) 1135-1143
2. Rodriguez-Maldonado E., Hernandez-Rebollar A.E., Lopez-Marure R., et al. Role of tumor necrosis factor alpha in atherosclerosis. Arch Cardiol Mex 71 (2001) 241-249
3. Rus H.G., Niculescu F., and Vlaicu R. Tumor necrosis factor-alpha in human arterial wall with atherosclerosis. Atherosclerosis 89 (1991) 247-254
4. Mizia-Stec K., Zahorska-Markiewicz B., Mandecki T., et al. Hyperlipidaemias and serum cytokines in patients with coronary artery disease. Acta Cardiol 58 (2003) 9-15
5. Skoog T., Dichtl W., Boquist S., et al. Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men. Eur Heart J 23 (2002) 376-383
6. Cesari M., Penninx B.W., Newman A.B., et al. Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation 108 (2003) 2317-2322
7. Lau D.C., Dhillon B., Yan H., et al. Adipokines: molecular links between obesity and atherosclerosis. Am J Physiol Heart Circ Physiol 288 (2005) H2031-H2041
8. Sewter C.P., Digby J.E., Blows F., et al. Regulation of tumour necrosis factor-alpha release from human adipose tissue in vitro. J Endocrinol 163 (1999) 33-38
9. Hotamisligil G.S., Shargill N.S., and Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259 (1993) 87-91
10. Hotamisligil G.S., and Spiegelman B.M. Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes 43 (1994) 1271-1278
11. Chandran M., Phillips S.A., Ciaraldi T., et al. Adiponectin: more than just another fat cell hormone?. Diabetes Care 26 (2003) 2442-2450
12. Koshiyama H., Shimono D., Kuwamura N., et al. Rapid communication: inhibitory effect of pioglitazone on carotid arterial wall thickness in type 2 diabetes. J Clin Endocrinol Metab 86 (2001) 3452-3456
13. Dormandy J.A., Charbonnel B., Eckland D.J., et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 366 (2005) 1279-1289
14. Blaschke F., Spanheimer R., Khan M., et al. Vascular effects of TZDs: new implications. Vascul Pharmacol 45 (2006) 3-18
15. Shimizu H., Oh-I S., Tsuchiya T., et al. Pioglitazone increases circulating adiponectin levels and subsequently reduces TNF-alpha levels in Type 2 diabetic patients: a randomized study. Diabet Med 23 (2006) 253-257
16. Miyazaki Y., Mahankali A., Wajcberg E., et al. Effect of pioglitazone on circulating adipocytokine levels and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab 89 (2004) 4312-4319
17. Enomoto N., Takei Y., Yamashima S., et al. Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization. Alcohol Clin Exp Res 29 (2005) 216S-219S
18. Uchimura K., Nakamuta M., Enjoji M., et al. Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells. Hepatology 33 (2001) 91-99
19. Rodbell M. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem 239 (1963) 375-380
20. Kudo T., Nakayama E., Suzuki S., et al. Cholesterol diet enhances daily rhythm of Pai-1 mRNA in the mouse liver. Am J Physiol Endocrinol Metab 287 (2004) E644-E651
21. Han S.N., Leka L.S., Lichtenstein A.H., et al. Effect of hydrogenated and saturated, relative to polyunsaturated, fat on immune and inflammatory responses of adults with moderate hypercholesterolemia. J Lipid Res 43 (2002) 445-452
22. Netea M.G., Demacker P.N., de Bont N., et al. Hyperlipoproteinemia enhances susceptibility to acute disseminated Candida albicans infection in low-density-lipoprotein-receptor-deficient mice. Infect Immun 65 (1997) 2663-2667
23. Szapary P.O., Bloedon L.T., Samaha F.F., et al. Effects of pioglitazone on lipoproteins, inflammatory markers, and adipokines in nondiabetic patients with metabolic syndrome. Arterioscler Thromb Vasc Biol 26 (2006) 182-188
24. Hetzel J., Balletshofer B., Rittig K., et al. Rapid effects of rosiglitazone treatment on endothelial function and inflammatory biomarkers. Arterioscler Thromb Vasc Biol 25 (2005) 1804-1809
25. Taniguchi J., Honda H., Shibusawa Y., et al. Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia. Vascul Pharmacol 43 (2005) 47-55
26. Moroe H., Fujii H., Honda H., et al. Characterization of endothelium-dependent relaxation and modulation by treatment with pioglitazone in the hypercholesterolemic rabbit renal artery. Eur J Pharmacol 497 (2004) 317-325
27. Zhao s.p., and Wu J. Fenofibrate reduces tumor necrosis factor-alpha serum concentration and adipocyte secretion of hypercholesterolemic rabbits. Clin Chim Acta 347 (2004) 145-150
28. Coats A.J. Ethical authorship and publishing. Int J Cardiol 131 (2009) 149-150