Leptin concentrations and the immune-mediated reduction of feed intake in sheep infected with the nematode Trichostrongylus colubriformis

British Journal of Nutrition

Volumn 102, Issue 7, 2009, Pages 954-957

  Greer, Andrew W ^a   Boisclair, Yves R ^b   Stankiewicz, Miroslaw ^a   McAnulty, Robin W ^a   Jay, Nigel P ^a   Sykes, Andrew R ^a  

^a LINCOLN UNIVERSITY   (New Zealand)

^b Cornell University ^*  (United States)

Author keywords

Anorexia; Body composition; Leptin; Nematoda; Ovine nutrition

Indexed keywords

DEPREDONE; LEPTIN; METHYLPREDNISOLONE ACETATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANOREXIA; ARTICLE; CALORIC RESTRICTION; CARCASS; CONTROLLED STUDY; FACTORIAL DESIGN; FEEDBACK SYSTEM; FEMALE; FOOD INTAKE; HORMONE BLOOD LEVEL; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; SHEEP; TRICHOSTRONGYLOSIS; TRICHOSTRONGYLUS COLUBRIFORMIS;

ADIPOSE TISSUE; ANIMALS; ANOREXIA; EATING; FECES; FEMALE; GLUCOCORTICOIDS; LEPTIN; PARASITE EGG COUNT; SHEEP; SHEEP DISEASES; TRICHOSTRONGYLOSIS;

ANIMALIA; NEMATODA; OVIS; OVIS ARIES; TRICHOSTRONGYLUS COLUBRIFORMIS;

EID: 73649098297     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114509359115     Document Type: Article

References (14)

1. Greer AW, Stankiewicz M, Jay NP, et al. (2005) The effect of concurrent corticosteroid-induced immuno-suppression and infection with the intestinal parasite Trichostrongylus colubriformis on feed intake and utilisation in both immunologically naive and competent sheep. Anim Sci 80, 89-99.
2. Johnson RW (1998) Immune and endocrine regulation of food intake in sick animals. Domest Anim Endocrinol 15, 309-319.
3. Lord GM, Matarese G, Howard JK, et al. (1998) Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394, 897-901.
4. Mastronardi CA, Yu WH, Rettori V, et al. (2000) Lipopolysaccharide- induced leptin release is not mediated by nitric oxide, but is blocked by dexamethasone. Neuroimmunomodulation 8, 91-97.
5. Ehrhardt RA, Slepetis RM, Siegal-Willlott J, et al. (2000) Development of a specific radioimmunoassay to measure physiological changes in circulating leptin in cattle and sheep. J Endocrinol 166, 519-528.
6. Agriculture and Food Research Council (1993) Energy and Protein Requirements of Ruminants. An advisory manual prepared by the Agriculture and Food Research Council technical committee on responses to nutrients. Wallingford: CAB International.
7. Bown MD, Poppi DP & Sykes AR (1991) The effect of postruminal infusion of protein or energy on the pathophysiology of Trichostrongylus colubriformis infection and body composition in lambs. Aust J Agric Res 42, 253-267.
8. Ministry of Agriculture, Fisheries and Food (1979) Manual of Veterinary Parasitological Laboratory Techniques. London: Her Majesty's Stationery Office.
9. Fox MT, Reynolds GW, Scott I, et al. (2006) Vagal and splanchnic afferent nerves are not essential for anorexia associated with abomasal parasitism in sheep. Vet Parasitol 135, 287-295.
10. Zaralis K, Tolkamp BJ, Houdijk JGK, et al. (2008) Changes in food intake and circulating leptin due to gastrointestinal parasitism in lambs of two breeds. J Anim Sci 86, 1891-1903.
11. Zaralis K, Tolkamp BJ, Houdijk JGK, et al. (2009) Consequences of protein supplementation for anorexia, expression of immunity and plasma leptin concentrations in parasitized ewes of two breeds. Br J Nutr 101, 499-509.
12. Faulconnier Y, Delavaud C & Chilliard Y (2003) Insulin and (or) dexamethasone effects on leptin production and metabolic activities of ovine adipose tissue explants. Reprod Nutr Dev 43, 237-250.
13. Forhead AJ, Thomas L, Crabtree J, et al. (2002) Plasma leptin concentration in fetal sheep during late gestation: ontogeny and effect of glucocorticoids. Endocrinology 143, 1166-1173.
14. Delavaud C, Bocquier F, Baumont R, et al. (2007) Body fat content and feeding level interact strongly in the short- and medium-term regulation of plasma leptin during underfeeding and re-feeding in adult sheep. Br J Nutr 98, 106-115.