Automation process for morphometric analysis of volumetric CT data from pulmonary vasculature in rats

Computer Methods and Programs in Biomedicine

Volumn 97, Issue 1, 2010, Pages 62-77

  Shingrani, Rahul ^a   Krenz, Gary ^a,b,c,d   Molthen, Robert ^a,b,d  

^a Medical College of Wisconsin and Marquette University   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c MARQUETTE UNIVERSITY   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

3 D; Automated; CT; Measurement; Morphometry; Segmentation; Vessel

Indexed keywords

ANIMAL MODEL; ARTERIAL TREE; AUTOMATED; AUTOMATED ALGORITHMS; AUTOMATION PROCESS; BIOMECHANICAL PROPERTIES; DATA SETS; FUNCTIONAL ATTRIBUTE; IMAGE PROCESSING LIBRARIES; IN-VESSEL; MEDICAL IMAGING SCANNERS; MICRO CT; MORPHOMETRIC ANALYSIS; MORPHOMETRY; MULTI-DIMENSIONAL DATASETS; NUMERIC OPTIMIZATION; OPERATOR INTERVENTIONS; PULMONARY VASCULATURE; REPEATED MEASUREMENTS; THREE DIMENSIONAL SEGMENTATION; TWO STAGE; VASCULAR STRUCTURES; VASCULAR TREES; VESSEL DIAMETER; VOLUMETRIC CT;

AUTOMATION; BIOMECHANICS; COMPUTERIZED TOMOGRAPHY; DATA HANDLING; IMAGE PROCESSING; MATHEMATICAL MODELS; MATHEMATICAL MORPHOLOGY; MATHEMATICAL OPERATORS; MEDICAL IMAGING; THREE DIMENSIONAL;

PHYSIOLOGICAL MODELS;

ALGORITHM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOMATION; BLOOD VESSEL DIAMETER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DATA ANALYSIS; DATA BASE; IMAGE PROCESSING; LUNG ARTERY; LUNG BLOOD VESSEL; LUNG DISEASE; MATHEMATICAL MODEL; MORPHOMETRICS; NONHUMAN; PROCESS OPTIMIZATION; RAT; VOLUMETRY;

ALGORITHMS; ANGIOGRAPHY; ANIMALS; CONE-BEAM COMPUTED TOMOGRAPHY; CONTRAST MEDIA; FLUOROCARBONS; LUNG; MODELS, ANATOMIC; MODELS, CARDIOVASCULAR; PULMONARY CIRCULATION; RADIOGRAPHIC IMAGE ENHANCEMENT; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS AS TOPIC;

EID: 73649083709     PISSN: 01692607     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmpb.2009.07.009     Document Type: Article

References (31)

1. Bradley W.G. Radiology 2002: near term advances in medical imaging. Medscape Radiol. (2001)
2. Bartling S.H., Stiller W., Grasruck M., Schmidt B., Peschke P., Semmler W., and Kiessling F. Retrospective motion gating in small animal CT of mice and rats. Invest. Radiol. 42 10 (2007) 704-714
3. Hu J., Haworth S.T., Molthen R.C., and Dawson C.A. Dynamic small animal lung imaging via a postacquisition respiratory gating technique using micro-cone beam computed tomography. Acad. Radiol. 11 9 (2004) 961-970
4. Karau K.L., Johnson R.H., Molthen R.C., Dhyani A.H., Haworth S.T., Hanger C.C., Roerig D.L., and Dawson C.A. Microfocal X-ray CT imaging and pulmonary arterial distensibility in excised rat lungs. Am. J. Physiol. - Heart Circul. Physiol. 281 3 (2001) H1447-H1457
5. S. Grosskopf, C. Biermann, K. Deng, Y. Chen, Accurate, fast, and robust vessel contour segmentation of CTA using an adaptive self-learning edge model, Medical Imaging 2009: Image Processing, Lake Buena Vista, FL, USA, SPIE 2009, pp. 72594D-8.
6. S. Kawajiri, X. Zhou, X. Zhang, T. Hara, H. Fujita, R. Yokoyama, H. Kondo, M. Kanematsu, H. Hoshi, Automated segmentation of hepatic vessel trees in non-contrast x-ray CT images, Medical Imaging 2007: Image Processing, San Diego, CA, USA, SPIE 2007, pp. 65123A-8.
7. Kubassova O. Automatic segmentation of blood vessels from dynamic MRI datasets. Med. Image Comput. Comput. Assist. Interv. Int. Conf. Med. Image Comput. Comput. Assist. Interv. 10 Pt 1 (2007) 593-600
8. Lee J., Beighley P., Ritman E., and Smith N. Automatic segmentation of 3D micro-CT coronary vascular images. Med. Image Anal. 11 6 (2007) 630-647
9. Lobregt S., Verbeek P.W., and Groen F.C.A. Three-dimensional skeletonization: principle and algorithm. IEEE Trans. Pattern Anal. Mach. Intell. PAMI-2 1 (1980) 75-77
10. C. Lorenz, J. Lessick, G. Lavi, T. Bulow, S. Renisch, Fast automatic delineation of cardiac volume of interest in MSCT images, Medical Imaging 2004: Image Processing, San Diego, CA, USA, SPIE 2004, pp. 456-466.
11. C. Lorenz, S. Renisch, T. Schlathoelter, T. Buelow, Simultaneous segmentation and tree reconstruction of the coronary arteries in MSCT images, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications, San Diego, CA, USA, SPIE 2003, pp. 167-177.
12. Zhou C., Chan H.P., Sahiner B., Hadjiiski L.M., Chughtai A., Patel S., Wei J., Ge J., Cascade P.N., and Kazerooni E.A. Automatic multiscale enhancement and segmentation of pulmonary vessels in CT pulmonary angiography images for CAD applications. Med. Phys. 34 12 (2007) 4567-4577
13. P. Bruyninckx, D. Loeckx, D. Vandermeulen, P. Suetens, Segmentation of lung vessel trees by global optimization, Medical Imaging 2009: Image Processing, Lake Buena Vista, FL, USA, SPIE 2009, pp. 725912-12.
14. T. Buelow, R. Wiemker, T. Blaffert, C. Lorenz, S. Renisch, Automatic extraction of the pulmonary artery tree from multi-slice CT data, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, San Diego, CA, USA, SPIE 2005, pp. 730-740.
15. J.N. Kaftan, A.P. Kiraly, A. Bakai, M. Das, C.L. Novak, T. Aach, Fuzzy pulmonary vessel segmentation in contrast enhanced CT data, Medical Imaging 2008: Image Processing, San Diego, CA, USA, SPIE 2008, pp. 69141Q-12.
16. L. Raghupathi, S. Lakare, A hybrid lung and vessel segmentation algorithm for computer aided detection of pulmonary embolism, Medical Imaging 2009: Computer-Aided Diagnosis, Lake Buena Vista, FL, USA, SPIE 2009, pp. 726033-10.
17. C. Zhou, H.-P. Chan, L.M. Hadjiiski, S. Patel, P.N. Cascade, B. Sahiner, J. Wei, J. Ge, E.A. Kazerooni, Automatic pulmonary vessel segmentation in 3D computed tomographic pulmonary angiographic (CTPA) images, Medical Imaging 2006: Image Processing, San Diego, CA, USA, SPIE 2006, pp. 61444Q-7.
18. Robb R.A., Hanson D.P., Karwoski R.A., Larson A.G., Workman E.L., and Stacy M.C. ANALYZE: a comprehensive, operator-interactive software package for multidimensional medical image display and analysis. Comput. Med. Imaging Graphics 13 (1989) 433-454
19. Robb R.A., and Barillot C. Interactive display and analysis of 3-D medical Images. IEEE Trans. Med. Imaging 8 3 (1989) 217-226
20. Robb R.A. The biomedical imaging resource at Mayo Clinic. IEEE Trans. Med. Imaging 20 9 (2001) 854-867
21. Feldkamp L.A., Davis L.C., and Kress J.W. Practical cone-beam algorithm. J. Opt. Soc. Am. A 1 (1984) 612-619
22. Molthen R.C., Karau K.L., and Dawson C.A. Quantitative models of the rat pulmonary arterial tree morphometry applied to hypoxia-induced arterial remodeling. J. Appl. Physiol. 97 6 (2004) 2372-2384 discussion 2354
23. Karau K.L., Molthen R.C., Dhyani A., Haworth S.T., Hanger C.C., Roerig D.L., Johnson R.H., and Dawson C.A. Pulmonary arterial morphometry from microfocal X-ray computed tomography. Am. J. Physiol. Heart Circ. Physiol. 281 6 (2001) H2747-H2756
24. M.I.A. Lourakis, levmar: Levenberg-Marquardt nonlinear least squares algorithms in C/C++. http://www.ics.forth.gr/∼lourakis/levmar/ 2004 [accessed: January 2005].
25. Unspecified, GNU General Public License. http://www.gnu.org/copyleft/gpl.html [accessed: January 2005].
26. al-Tinawi A., Madden J.A., Dawson C.A., Linehan J.H., Harder D.R., and Rickaby D.A. Distensibility of small arteries of the dog lung. J. Appl. Physiol. 71 (1991) 1714-1722
27. Zhuang F.Y., Fung Y.C., and Yen R.T. Analysis of blood flow in cat's lung with detailed anatomical and elasticity data. J. Appl. Physiol. 55 4 (1983) 1341-1348
28. Yen R.T., Fung Y.C., and Bingham N. Elasticity of small pulmonary arteries in the cat. J. Biomech. Eng. 102 2 (1980) 170-177
29. Blyth K.G., Syyed R., Chalmers J., Foster J.E., Saba T., Naeije R., Melot C., and Peacock A.J. Pulmonary arterial pulse pressure and mortality in pulmonary arterial hypertension. Respir. Med. 101 12 (2007) 2495-2501
30. Castelain V., Herve P., Lecarpentier Y., Duroux P., Simonneau G., and Chemla D. Pulmonary artery pulse pressure and wave reflection in chronic pulmonary thromboembolism and primary pulmonary hypertension. J. Am. Coll. Cardiol. 37 4 (2001) 1085-1092
31. Karau K.L., Molthen R., Johnson R.H., and Dawson C. Pulmonary arterial tree structure-function relationships from X-ray ct imaging. Ann. Biomed. Eng. 29 (2001) S136