Risk factors and outcomes for bloodstream infections with extended-spectrum β-lactamase-producing Klebsiella pneumoniae; Findings of the nosocomial surveillance system in Hungary

Acta Microbiologica et Immunologica Hungarica

Volumn 56, Issue 3, 2009, Pages 251-262

  Szilágyi, Emese ^a   Fuzi M ^b   Böröcz, Karolina ^a   Kurcz, Andrea ^a   Toth A ^a   Nagy, K ^b  

^a NATIONAL CENTER FOR EPIDEMIOLOGY   (Hungary)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

Esbl Klebsiella bacteremia; Outcome; Risk factors

Indexed keywords

ANTIBIOTIC AGENT; EXTENDED SPECTRUM BETA LACTAMASE;

ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BLOODSTREAM INFECTION; CAUSE OF DEATH; CENTRAL VENOUS CATHETER; COMORBIDITY; CONTROLLED STUDY; FEMALE; HEALTH SURVEY; HOSPITAL ADMISSION; HOSPITAL INFECTION; HUMAN; HUNGARY; INFECTION RISK; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE INFECTION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; OUTCOME ASSESSMENT; RISK ASSESSMENT; SURGICAL INFECTION; THERAPY DELAY; TREATMENT OUTCOME; URINARY CATHETER;

KLEBSIELLA; KLEBSIELLA PNEUMONIAE;

EID: 73549085884     PISSN: 12178950     EISSN: 15882640     Source Type: Journal    
DOI: 10.1556/AMicr.56.2009.3.5     Document Type: Article

References (22)

1. Knothe, H., Sarah, P., Antal, M., Mitsuhashi, S.: Transferable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of Klebsiella pneumoniae and Serratia marcescens. Infection 11, 315-317 (1983).
2. Coque, T. M., Baquero, F., Canton, R.: Increasing prevalence of ESBL-producing Enterobacteriaceae in Europe. Euro Surveill 13 (47), pii=19044 (2008). Available online: http://www.eurosurveillance.org/ViewArticle. sp
3. Schwaber, M. J., Navon-Venezia, S., Kaye, K. S., Ben-Ami, R., Schwartz, D., Carmeli, Y.: Clinical and economic impact of bacteremia with extended-spectrum β-lactamase-producing Enterobacteriacae. Antimicrob Agents Chemother 50, 1257-1263 (2006).
4. Cordery, R. J., Roberts, C. H., Cooper, S. J., Bellinghan, G., Shetty, N.: Evaluation of risk factors for acquisition of bloodstream infections with extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species in the intensive care unit; antibiotic management and clinical outcome. J Hosp Infect 68, 105-115 (2008).
5. Lauterbach, E., Patel, J. B., Bilker, W. B., Edelstein, P. H., Fishman, N. O.: Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: Risk factors for infection and impact of resistance on outcomes. Clin Infect Dis 32, 1162-1171 (2001).
6. Skippen, I., Shemko, M., Turton, J., Kaufman, M. E., Palmer, C., Shetty, N.: Epidemiology of infections caused by extended-spectrum β-lactamase- producing Escherichia coli and Klebsiella spp. : A nested case-control study from a tertiary hospital in London. J Hosp Infect 64, 115-123 (2006).
7. Bhavnani, S. M., Ambrose, P. G., Craig, W. A., Dudley, M. N., Jones, R. N.: Outcomes evaluation of patients with ESBL and non-ESBL-producing Escherichia coli and Klebsiella species as defined by CLSI reference methods: report from the SENTRY Antimicrobial Surveillance Program. Diagn Microbiol Infect Dis 16, 16 (2006).
8. Ramphal, R., Ambrose, P. G.: Extended-spectrum beta-lactamases and clinical outcomes: Current data. Clin Infect Dis 42 (Suppl. 4), S:S164-S172 (2006).
9. Tumbarello, M., Sanguinetti, M., Montouri, E.: Predictors of mortality in patients with bloodstream infections caused by extended-spectrum beta-lactamase-producing Enterobacteriacae: Importance of inadequate initial antimicrobial treatment. Antimicrob Agents Chemother 51, 1987-1994 (2007).
10. Kanafani, Z. A., Meiho-Sibai, Abla, Araj, G. F., Kanaan, M., Kanj, S. S.: Epidemiology and risk factors for extended-spectrum β-lactamase-producing organisms: A case control study at a tertiary care center in Lebanon. Am J Infect Control 33, 326-332 (2005).
11. Mosqueda-Gomes, J. L., Montano-Losa, A., Rolon, A. L., Cervantes, C., Bobadilladel-Valle, M., Silva-Sanchez, J.: Molecular epidemiology and risk factors of Bloodstream infections caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae, a case control study. Int J Infect Dis 12, 653-659 (2008).
12. Lin, M. F., Huang, M. L., Lai, S. H.: Risk factors int he acquisition of extended-spectrum β-lactamase-producing Klebsiella pneumoniae: A case-control study in a district hospital in Taiwan. J Hosp Infect 53, 39-45 (2003).
13. Kristóf, K., Szabó, D., Marsh, J. W., Janik, L., Rozgonyi, F., Nobilis, A., Nagy, K.: Extended-spectrum β-lactamase-producing Klebsiella spp. In a neonatal intensive care unit: risk factors for the infection and the dynamics of the molecular epidemiology. Eur J Clin Microbiol Infect Dis 26, 563-570 (2007).
14. Tuner, P. J. Extended-spectrum beta-lactamases. Clin Infect Dis 41 (Suppl. 4), S274-S275 (2005).
15. Damjanova, I., Tóth, Á., Pászti, J., Hajbel-Vékony, G., Jakab, M., Berta, J., Füzi, M.: Expansion and countrywide dissemination of ST 11, ST 15 and ST 147 ciprofloxacin-resistant CTX-M-15 type β-lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005-the new 'MRSA'? J Antimicrob Chemother 62, 978-985 (2008).
16. The European Antimicrobial Resistance Surveillance System.
17. Szilágyi, E., Böröcz, K., Gastmeier, P., Kurcz, A., Horváth-Puhó, E.: The national nosocomial surveillance network in Hungary: Results of two years of surgical site infection surveillance. J Hosp Infect 71, 74-80 (2009).
18. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Fifteenth International Supplement M100-S15. CLSI, Wayne, PA, USA, 2005.
19. Jacoby, G. A., Munoz-Price, L. S.: The new beta-lactamases. N Engl J Med 352, 380-391 (2005).
20. Zaoutis, T. E., Goyal, M., Chu, J. H.: Risk factors for and outcomes of bloodstream infection caused by extended-spectrum beta-lactamases-producing Escherichia coli and Klebsiella species in children. Pediatrics 115, 942-949 (2005).
21. Cosgrove, S. E., Carmeli, Y.: The impact of antimicrobial resistance on health and economic outcomes. Clin Infect Dis 36, 1433-1437 (2003).
22. Kim, Y. K., Pai, H., Lee, H. J., Park, S. E., Choi, E. H., Kim, J.: Bloodstream infections by extended-spectrum beta-lactamases-producing Escherichia coli and Klebsiella pneumoniae in children: epidemiology and clinical outcome. Antimicrob Agents Chemother 56, 148-191 (2002).