Neuromyelitis optica-IgG (aquaporin-4) autoantibodies in immune mediated optic neuritis

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 81, Issue 1, 2010, Pages 109-111

  Petzold, A ^a,b   Pittock, S ^c   Lennon, V ^c,d   Maggiore, C ^b   Weinshenker, B G ^c   Plant, G T ^b,e,f  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c Mayo Clinic   (United States)

^d MAYO GRADUATE SCHOOL   (United States)

^e MOORFIELDS EYE HOSPITAL   (United Kingdom)

^f ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN 4; AUTOANTIBODY; AZATHIOPRINE; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; NEUROMEYLITIS OPTICA IMMUNOGLOBULIN G AUTOANTIBODY; STEROID; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ANTIBODY BLOOD LEVEL; ARTICLE; DISEASE COURSE; DISEASE SEVERITY; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NEURITIS; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RECURRENT DISEASE; RELAPSE;

ADOLESCENT; ADULT; AGED; AQUAPORIN 4; AUTOANTIBODIES; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELITIS; NEUROMYELITIS OPTICA; OPTIC NEURITIS; PROGNOSIS; PROSPECTIVE STUDIES; SYNDROME; YOUNG ADULT;

EID: 73449147661     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2008.146894     Document Type: Article

References (15)

1. Lennon VA, Wingerchuk DM, Kryzer TJ, et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004;364:2106-12.
2. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 2005;202:473-7.
3. Roemer SF, Parisi JE, Lennon VA, et al. Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain 2007;130:1194-205.
4. Matiello M, Lennon VA, Jacob A, et al. NMO-IgG predicts the outcome of recurrent optic neuritis. Neurology 2008;70:2197-200.
5. Marignier R, De Seze J, Vukusic S, et al. NMO-IgG and Devic's neuromyelitis optica: a French experience. Mult Scler 2008;14:440-5.
6. Saiz A, Zuliani L, Blanco Y, et al. Revised diagnostic criteria for neuromyelitis optica (NMO): Application in a series of suspected patients. J Neurol 2007;254:1233-7.
7. Kidd D, Burton B, Plant G, et al. Chronic relapsing inflammatory optic neuropathy (CRION). Brain 2003;126:276-84.
8. Plant G. Optic neuritis and multiple sclerosis. Curr Opin Neurol 2008;21:16-21.
9. Hickman S, Dalton C, Miller D, et al. Management of acute optic neuritis. Lancet 2002;360:1953-62.
10. Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 2005;58:840-6.
11. Wingerchuk DM, Lennon VA, Pittock SJ, et al. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006;66:1485-9.
12. Takahashi T, Fujihara K, Nakashima I, et al. Establishment of a new sensitive assay for anti-human aquaporin-4 antibody in neuromyelitis optica. Tohoku J Exp Med 2006;210:307-13.
13. Paul F, Jarius S, Aktas O, et al. Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica. PLoS Med 2007;4:e133.
14. Jarius S, Aboul-Enein F, Waters P, et al. Antibody to aquaporin-4 in the long-term course of neuromyelitis optica. Brain 2008;131:3072-80.
15. Takahashi T, Fujihara K, Nakashima I, et al. Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre. Brain 2007;130:1178-80.