Molecular tests for coat colours in horses

Journal of Animal Breeding and Genetics

Volumn 126, Issue 6, 2009, Pages 415-424

  Rieder, Stefan ^a  

^a Swiss College of Agriculture   (Switzerland)

Author keywords

Behavior; Breed diversity; Color genetics; Domestication; Horse; Molecular tests

Indexed keywords

PIGMENT;

ANIMAL; GENETIC VARIABILITY; GENETICS; GENOTYPE; HAIR COLOR; HORSE; REVIEW;

ANIMALS; GENETIC VARIATION; GENOTYPE; HAIR COLOR; HORSES; PIGMENTS, BIOLOGICAL;

ANIMALIA; EQUIDAE;

EID: 73449137559     PISSN: 09312668     EISSN: 14390388     Source Type: Journal    
DOI: 10.1111/j.1439-0388.2009.00832.x     Document Type: Review

References (58)

1. Andersson L., Georges M. (2004) Domestic-animal genomics: deciphering the genetics of complex traits. Nat. Rev. Genet., 5, 202 212.
2. Andersson L.S., Juras R., Ramsey D.T., Eason-Butler J., Ewart S., Cothran G., Lindgren G. (2008) Equine Multiple Congenital Ocular Anomalies maps to a 4.9 megabase interval on horse chromosome 6. BMC Genet., 9, 88. DOI :.
3. Bellone R.R., Brooks S.A., Sandmeyer L., Murphy B.A., Forsyth G., Archer S., Bailey E., Grahn B. (2008) Differential gene expression of TRPM1, the potential cause of congenital stationary night blindness and coat spotting patterns (LP) in the Appaloosa Horse (Equus caballus). Genetics, 179, 1861 1870.
4. Bowling A.T. (2000) Genetics of colour variation. In : A.T. Bowling, A. Ruvinsky (eds The Genetics of the Horse. CAB International Oxen, UK, pp. 53 70.
5. Bricker S.J., Penedo C.M., Millon L.V., Murray J.D. (2003) Linkage of the dun coat color locus to microsatellites on horse chromosome 8. Plant & Animal Genomes XI conference, San Diego, CA, USA, P640.
6. Brooks S.A., Bailey E. (2005) Exon skipping in the KIT gene causes a Sabino spotting pattern in horses. Mamm. Genome, 16, 893 902.
7. Brooks S.A., Terry R.B., Bailey E. (2002) A PCR-RFLP for KIT associated with tobiano spotting pattern in horses. Anim. Genet., 33, 301 303.
8. Brooks S.A., Lear T.L., Adelson D.L., Bailey E. (2007) A chromosome inversion near the KIT gene and the Tobiano spotting pattern in horses. Cytogenet. Genome Res., 119, 225 230.
9. Bruford M.W., Bradley D.G., Luikart G. (2003) DNA Markers reveal the complexity of livestock domestication. Nat. Rev. Genet., 4, 900 910.
10. Brunberg E., Andersson L., Cothran G., Sandberg K., Mikko S., Lindgren G. (2006) A missense mutation in PMEL17 is associated with the Silver coat color in the horse. BMC Genet., 9, 46 55.
11. Chowdhary B.P., Bailey E. (2003) Equine genomics: galloping to new frontiers. Cytogenet. Genome Res., 102, 184 188.
12. Chowdhary B.P., Raudsepp T. (2008) The Horse Genome Derby: racing from map to whole genome sequence. Chromosome Res., 16, 109 127.
13. Cook D., Brooks S., Bellone R., Bailey E. (2008) Missense mutation in exon 2 of SLC36A1 responsible for champagne dilution in horses. PLOS Genet., 4, e1000195, 1-9.
14. Dobney K., Larson G. (2006) Genetics and animal domestication: new windows on an elusive process. J. Zool., 269, 261 271.
15. Fang M., Larson G., Soares Ribeiro H., Li N., Andersson L. (2009) Contrasting mode of evolution at a coat color locus in wild and domestic pigs. PLOS Genet., 5, e1000341, 1-6.
16. Gilbert S.F. (2006) Developmental Biology, 8th edn. Sinauer Associates, Inc., Sunderland, MA.
17. Grahn B.H., Pinard Ch., Archer S., Bellone R., Forsyth G., Sandmeyer L.S. (2008) Congenital ocular anomalies in purebred and crossbred Rocky and Kentucky Mountain horses in Canada. Can. Vet. J., 49, 675 681.
18. Grandin T. (1998) Genetics and the Behaviour of Domestic Animals. Academic Press, San Diego, CA.
19. Graphodatskaya D. (2002) Development of an in vitro cell culture gene expression technique to examine coat colour genes in cattle. PhD thesis no. 14773, Swiss Federal Institute of Technology, Zurich, CH.
20. Haase B., Brooks S.A., Schlumbaum A., Azor P.J., Bailey E., Alaeddine F., Mevissen M., Burger D., Poncet P.A., Rieder S., Leeb T. (2007) Allelic heterogeneity at the equine KIT locus in dominant white (W) horses. PLOS Genet., 3, e195, 1-8.
21. Haase B., Jude R., Brooks S.A., Leeb T. (2008) An equine chromosome 3 inversion is associated with the tobiano spotting pattern in German horse breeds. Anim. Genet., 39, 306 309.
22. Haase B., Brooks S.A., Tozaki T., Burger D., Poncet P.A., Rieder S., Hasegawa T., Penedo C., Leeb T. (2009a) Seven novel KIT mutations in horses with white coat colour phenotypes. Anim. Genet., 40, 623 629.
23. Haase B., Rieder S., Obexer-Ruff G., Burger D., Poncet P.A., Wade C., Leeb T. (2009b) White markings in the Franches-Montagnes horse population: positional cloning using genome wide SNP association mapping. Plant & Animal Genomes XVII conference, San Diego, CA, USA, W150.
24. Henner J., Poncet P.A., Aebi L., Hagger C., Stranzinger G., Rieder S. (2002a) Horse breeding: genetic tests for the coat colors chestnut, bay and black. Results from a first study in the Swiss Franches-Montagnes horse breed. Schweiz. Arch. Tierheilkd., 144, 405 412.
25. Henner J., Poncet P.A., Guérin G., Hagger C., Stranzinger G., Rieder S. (2002b) Genetic mapping of the (G)-locus responsible for the coat color phenotype "progressive greying with age" in horses (Equus caballus). Mamm. Genome, 13, 535 537.
26. Hintz H.F., Van Vleck L.D. (1979) Lethal dominant roan in horses. J. Hered., 70, 145 146.
27. Klungland H., Vage D.I. (2000) Molecular genetics of pigmentation in domestic animals. Curr. Genomics, 1, 223 242.
28. Locke M.M., Ruth L.S., Millon L.V., Penedo M.C., Murray J.D., Bowling A.T. (2001) The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21. Anim. Genet., 32, 340 343.
29. Locke M.M., Penedo M.C., Bricker S.J., Millon L.V., Murray J.D. (2002) Linkage of the grey coat colour locus to microsatellites on horse chromosome 25. Anim. Genet., 33, 329 337.
30. Ludwig A., Pruvost M., Reissmann M., Benecke N., Brockmann G.A., Castaños P., Cieslak M., Lippold S., Llorente L., Malaspinas A., Slatkin M., Hofreiter M. (2009) Coat color variation at the beginning of horse domestication. Science, 324, 5926. 485.
31. Mariat D., Taourit S., Guérin G. (2003) A mutation in the MATP gene causes the cream coat colour in the horse. Genet. Sel. Evol., 35, 119 133.
32. Marklund S., Moller M.J., Sandberg K., Andersson L. (1996) A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses. Mamm. Genome, 7, 895 899.
33. Marklund S., Moller M.J., Sandberg K., Anderson L. (1999) Close association between sequence polymorphism in the KIT gene and the roan coat color in horses. Mamm. Genome, 10, 283 288.
34. Mau C., Poncet P.A., Bucher B., Stranzinger G., Rieder S. (2004) Genetic mapping of dominant white (W), a homozygous lethal condition in the horse (Equus caballus). J. Anim. Breed. Genet., 121, 374 383.
35. Metallinos D.L., Bowling A.T., Rine J. (1998) A missense mutation in the endothelin-B receptor gene is associated with lethal white foal syndrome: an equine version off hirschsprung disease. Mamm. Genome, 9, 426 431.
36. Nordlund J.J., Boissy R.E., Hearing V.J., King R.A., Ortonne J.P. (1998) The Pigmentary System - Physiology and Pathophysiology. Oxford University Press, New York.
37. Pielberg G., Mikko S., Sandberg K., Andersson L. (2005) Comparative linkage mapping of the grey coat colour gene in horses. Anim. Genet., 36, 390 395.
38. Pulos W.L., Hutt F.B. (1969) Lethal dominant white in horses. J. Hered., 60, 59 63.
39. Reissmann M., Bierwolf J., Brockmann G.A. (2007) Two SNPs in the SILV gene are associated with silver coat colour in ponies. Anim. Genet., 38, 1 6.
40. Rieder S. (1999) Angewandte vergleichende Genetik am Beispiel des Melanoms beim Pferd. Dissertation. ETH Nr. 13071. Ref.: G. Stranzinger; Korref.: E. Bailey; Korref.: U. Braun. http://e-collection.ethbib.ethz.ch/
41. Rieder S., Stricker C., Joerg H., Dummer R., Stranzinger G. (2000) A comparative genetic approach for the investigation of ageing grey horse melanoma. J. Anim. Breed. Genet., 117, 73 82.
42. Rieder S., Taourit S., Mariat D., Langlois B., Guérin G. (2001) Mutations in the agouti (ASIP), the extension (MC1R) and the brown (TYRP1) loci and their association to coat colour phenotypes in horses. Mamm. Genome, 12, 450 455.
43. Rieder S., Hagger Ch., Obexer-Ruff G., Leeb T., Poncet P.A. (2008) Genetic analysis of white facial and leg markings in the Swiss Franches-Montagnes horse breed. J. Hered., 99, 130 136.
44. Rosengren Pielberg G., Golovko A., Sundström E., Curik I., Lennartsson J., Seltenhammer M.H., Druml T., Binns M., Fitzsimmons C., Lindgren G., Sandberg K., Baumung R., Vetterlein M., Strömberg S., Grabherr M., Wade C., Lindblad-Toh K., Pontén F., Heldin C.H., Sölkner J., Andersson L. (2008) A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse. Nat. Genet., 40, 1004 1009.
45. Royo L.J., Fernández I., Azor P.J., Álvarez I., Pérez-Pardal L., Goyache F. (2008) Anovel method for routine genotyping of horse coat color gene polymorphisms. J. Anim. Sci., 86, 1291 1295.
46. Santschi E.M., Purdy A.K., Valber S.J., Vrotsos P.D., Kaese H., Mickelson J.R. (1998) Endothelin receptor B polymorphism associated with lethal white foal syndrome in horses. Mamm. Genome, 9, 306 309.
47. Santschi E.M., Vrotsos P.D., Purdy A.K., Mickelson J.R. (2001) Incidence of the endothelin receptor B mutation that causes lethal white foal syndrome in white-patterned horses. Am. J. Vet. Res., 62, 97 103.
48. Sölkner J., Seltenhammer M., Curik I., Niebauer G. (2004) Genetic relationships between speed of greying, melanoma and vitiligo prevalence in grey horses. Paper G.5.3 In: EAAP-Book of Abstracts No. 10: 55th Annual Meeting of the European Association for Animal Production, 05.-08.09.2004, Bled, Slovenia, 83. Editor in chief: Y. van der Honing. Wageningen Academic Publishers, Wageningen, NL, p. 83.
49. Sponenberg D.P. (2009) Equine Color Genetics, 3rd edn. Iowa State University Press, Ames, IA.
50. Stachurska A., Pieta M., Lojek J., Szulowska J. (2007) Performance in racehorses of various colours. Livest. Sci., 106, 282 286.
51. Swinburne J.E., Hopkins A., Binns M.M. (2002) Assignment of the horse grey coat colour gene to ECA 25 using whole genome scanning. Anim. Genet., 33, 338 342.
52. Terry R.B., Bailey E., Bernoco D., Cothran E.G. (2001) Linked markers exclude KIT as the gene responsible for appaloosa coat colour spotting patterns in horses. Anim. Genet., 32, 98 101.
53. Terry R.B., Bailey E., Lear T., Cothran E.G. (2002) Rejection of MITF and MGF as the genes responsible for appaloosa coat colour patterns in horses. Anim. Genet., 33, 82 84.
54. Terry R.B., Archer S., Brooks S., Bernoco D., Bailey E. (2004) Assignment of the appaloosa coat colour gene (LP) to equine chromosome 1. Anim. Genet., 35, 134 137.
55. Trut L.N. (1999) Early canid domestication: the Farm-Fox experiment. Am. Sci., 87, 160 169.
56. Wagner H.J., Reissmann M. (2000) New polymorphism detected in the horse MC1R gene. Anim. Genet., 31, 289 290.
57. Woolf C.M. (1992) Common white facial markings in Arabian horses that are homozygous and heterozygous for alleles at the A and E loci. J. Hered., 83, 73 77.
58. Yang G.C., Croaker D., Zhang A.L., Manglick P., Cartmill T., Cass D. (1998) A dinucleotide mutation in the endothelin-B receptor gene is associated with lethal white foal syndrome (LWFS) - a horse variant of Hirschsprung-disease (HSCR). Hum. Mol. Genet., 7, 1047 1052.