National assessment of medicare prescription plan coverage gaps among patients with atrial fibrillation in the US

Advances in Therapy

Volumn 26, Issue 8, 2009, Pages 784-794

  Kim, Michael H ^a   Lin, Jay ^b   Kreilick, Charles ^c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b SANOFI   (France)

^c ProUnlimited   (United States)

Author keywords

Atrial fibrillation; Comorbidities; Coverage gap; Donut hole; Medicare Part D; Prescription costs

Indexed keywords

ANTICOAGULANT AGENT; CARDIOVASCULAR AGENT;

AGED; ARTICLE; BILLING AND CLAIMS; COMORBIDITY; DRUG COST; FEMALE; HEALTH CARE COST; HEART ATRIUM FIBRILLATION; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICARE; OUTPATIENT CARE; POPULATION RESEARCH; PRESCRIPTION; RETROSPECTIVE STUDY;

AGED; AGED, 80 AND OVER; AMBULATORY CARE; ATRIAL FIBRILLATION; DRUG COSTS; DRUG PRESCRIPTIONS; FEMALE; FINANCING, PERSONAL; HEALTH SERVICES RESEARCH; HOSPITALIZATION; HUMANS; INSURANCE CLAIM REVIEW; INSURANCE COVERAGE; MALE; MEDICARE PART D; RETROSPECTIVE STUDIES; UNITED STATES;

EID: 73449127192     PISSN: 0741238X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12325-009-0054-1     Document Type: Article

References (24)

1. A.S. Go E.M. Hylek K.A. Phillips 2001 Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study JAMA 285 2370 2375 11343485 10.1001/jama.285.18.2370 1:STN:280: DC%2BD3M3ntleitQ%3D%3D
2. G. Thrall D. Lane D. Carroll G.Y. Lip 2006 Quality of life in patients with atrial fibrillation: a systematic review Am J Med. 119 448 16651058 10.1016/j.amjmed.2005.10.057
3. E.J. Benjamin P.A. Wolf R.B. D'Agostino H. Silbershatz W.B. Kannel D. Levy 1998 Impact of atrial fibrillation on the risk of death: the Framingham Heart Study Circulation 98 946 952 9737513 1:STN:280:DyaK1cvgslGgsw%3D%3D
4. A.D. Krahn J. Manfreda R.B. Tate F.A. Mathewson T.E. Cuddy 1995 The natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba Follow-Up Study Am J Med. 98 476 484 7733127 10.1016/S0002-9343(99)80348-9 1:STN:280:DyaK2M3ltVyjsw%3D%3D
5. P.A. Wolf J.B. Mitchell C.S. Baker W.B. Kannel R.B. D'Agostino 1998 Impact of atrial fibrillation on mortality, stroke, and medical costs Arch Intern Med. 158 229 234 9472202 10.1001/archinte.158.3.229 1:STN:280: DyaK1c7jt1OrtQ%3D%3D (Pubitemid 28123885)
6. D. Lloyd-Jones R. Adams M. Carnethon 2009 Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation 119 e21 181 19075105 10.1161/CIRCULATIONAHA.108.191261
7. Y. Miyasaka M.E. Barnes B.J. Gersh 2006 Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence Circulation 114 119 125 16818816 10.1161/CIRCULATIONAHA.105.595140 (Pubitemid 44420743)
8. K. Lakshminarayan C.A. Solid A.J. Collins D.C. Anderson C.A. Herzog 2006 Atrial fibrillation and stroke in the general Medicare population: a 10-year perspective (1992 to 2002) Stroke 37 1969 1974 16809573 10.1161/01.STR. 0000230607.07928.17 (Pubitemid 44309888)
9. P.B. Bach M.B. McClellan 2005 A prescription for a modern Medicare program N Engl J Med. 353 2733 2735 16382056 10.1056/NEJMp058249 1:CAS:528:DC%2BD28XntFeg (Pubitemid 43016809)
10. Medicare. The Official U.S. Government Site for People with Medicare http://www.medicare.gov/. Accessed February 24, 2009.
11. Hoadley J, Hargrave E, Cubanski J, Neuman T. The Medicare Drug Benefit: the Medicare Part D coverage gap: costs and consequences in 2007. The Henry J. Kaiser Family Foundation; August 2008.
12. S.X. Sun K.Y. Lee 2007 The Medicare Part D doughnut hole: effect on pharmacy utilization Manag Care Interface 20 51 55 18161394 1:CAS:528: DC%2BD2sXlsFCntro%3D
13. Y. Zhang J.M. Donohue J.P. Newhouse J.R. Lave 2009 The effects of the coverage gap on drug spending: a closer look at Medicare Part D Health Aff (Millwood) 28 w317 w325 10.1377/hlthaff.28.2.w317
14. C. Evans-Molina S. Regan L.E. Henault E.M. Hylek G.R. Schwartz 2007 The new Medicare Part D prescription drug benefit: an estimation of its effect on prescription drug costs in a Medicare population with atrial fibrillation J Am Geriatr Soc. 55 1038 1043 17608876 10.1111/j.1532-5415.2007.01285.x (Pubitemid 47024633)
15. W.A. Blumentals A. Gomez-Caminero S. Joo V. Vannappagari 2004 Should erectile dysfunction be considered as a marker for acute myocardial infarction? Results from a retrospective cohort study Int J Impot Res. 16 350 353 14985780 10.1038/sj.ijir.3901174 1:STN:280:DC%2BD2czmvVGguw%3D%3D (Pubitemid 39273762)
16. R.C. Kessler C.R. Cantrell P. Berglund M.C. Sokol 2007 The effects of copayments on medication adherence during the first two years of prescription drug treatment J Occup Environ Med. 49 597 609 17563602 10.1097/JOM. 0b013e318057772b (Pubitemid 46918851)
17. D.I. Brixner K.C. Jackson II X. Sheng R.E. Nelson A. Keskinaslan 2008 Assessment of adherence, persistence, and costs among valsartan and hydrochlorothiazide retrospective cohorts in free- and fixed-dose combinations Curr Med Res Opin. 24 2597 2607 18812017 10.1185/03007990802319364 1:CAS:528:DC%2BD1cXhtlKit7rE
18. A.C. Spyropoulos J. Lin 2007 Direct medical costs of venous thromboembolism and subsequent hospital readmission rates: an administrative claims analysis from 30 managed care organizations J Manag Care Pharm. 13 475 486 17672809
19. K.S. Coyne C. Paramore S. Grandy M. Mercader M. Reynolds P. Zimetbaum 2006 Assessing the direct costs of treating nonvalvular atrial fibrillation in the United States Value Health 9 348 356 16961553 10.1111/j.1524-4733.2006. 00124.x (Pubitemid 44337788)
20. D.A. Taira K.S. Wong F. Frech-Tamas R.S. Chung 2006 Copayment level and compliance with antihypertensive medication: analysis and policy implications for managed care Am J Manag Care 12 678 683 17090224
21. A. Pedan L. Varasteh S. Schneeweiss 2007 Analysis of factors associated with statin adherence in a hierarchical model considering physician, pharmacy, patient, and prescription characteristics J Manag Care Pharm. 13 487 496 17672810
22. M.E. Chernew M.R. Shah A. Wegh 2008 Impact of decreasing copayments on medication adherence within a disease management environment Health Aff (Millwood) 27 103 112 10.1377/hlthaff.27.1.103 (Pubitemid 351198595)
23. The Henry J. Kaiser Family Foundation. Medicare: a primer. January, 2009; Available at http://www.kff.org/medicare/upload/7615-02.pdf. Accessed June 2, 2009.
24. Pamuk E, Makuc D, Heck K, Reuben C, Lochner K. NCHS: Socioeconomic status and health chartbook. Health, United States, 1998. Hyattsville, MD: National Center for Health Statistics; 1998.