Effect of N-acetylcysteine on microalbuminuria in patients with acute respiratory distress syndrome

Archives of Medical Science

Volumn 5, Issue 3, 2009, Pages 408-414

  Najafi, Atabak ^a   Mojtahedzadeh, Mojtaba ^a,b   Mahmoodpoor, Ata ^a   Aghamohammadi, Mostafa ^a   Ahmadi, Arezou ^a   Nahreini, Sheida ^b   Pazuki, Marzieh ^a   Khajavi, Mohammad Reza ^a   Abdollahi, Mohammad ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acute respiratory distress syndrome; Microalbuminuria; N acetylcysteine

Indexed keywords

ACETYLCYSTEINE; CREATININE;

ABSENCE OF SIDE EFFECTS; ACUTE LUNG INJURY; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; APACHE; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD PRESSURE; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE URINE LEVEL; DRUG MECHANISM; EARLY INTERVENTION; FEMALE; HUMAN; HYPOXEMIA; MALE; MICROALBUMINURIA; OXIDATIVE STRESS; PREDICTION; SCORING SYSTEM; SURVIVAL RATE; TREATMENT RESPONSE; URINALYSIS;

EID: 73449113303     PISSN: 17341922     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Levy B, Shapiro SD. Acute respiratory distress syndrome. In: Kasper DL, et al. Harrisons principle of international medicine. McGraw Hill 2005; 1592-5.
2. Vazin A, Mojtahedzadeh M, Salehifar E, Rastkari N, Khalaj S, Rezaie A. Future drugs for treatment of acute respiratory distress syndrome. Int J Pharmacol 2005; 1: 9-16.
3. Summer WR. Respiratory failure. In: Goldman L, Bennett JC. Cecils textbook of medicine. W.B. Saunders Company 2000; 468-9.
4. Ware LB, Mattay MA. Medical progress: the acute respiratory distress syndrome. N Eng J Med 2000; 342: 1334-49.
5. Lee WL, Downey GP. Neutrophil activation and acute lung injury. Curr Opin Crit Care 2001; 7: 1-7.
6. Behr J, Maier K, Krombach F, Adelmann-Grill BC. Pathogenetic significance of reactive oxygen species in diffuse fibrosing alveolitis. Am Rev Respir Dis 1991; 144: 146-50.
7. Salari P, Mojtahedzadeh M, Abdollahi M. Influence of serum epidermal growth factor on mechanical ventilation and survival in patients with acute respiratory distress syndrome. Therapy 2005; 2: 393-8.
8. Hadidi E, Mojtahedzadeh M, Paknejad MH. Alterations of blood IL-8, TGFbeta1 and nitric oxide levels in relation to blood cells in patients with acute brain injury. Therapy 2006; 3: 413-9.
9. Vazin A, Mojtahedzadeh M, Najafi A, Khalilzadeh A, Abdollahi M. Relationship between duration, fatality rate and severity of disease and epidermal growth factor in human acute lung injury. Therapy 2005; 2: 255-9.
10. Soltan-Sharifi MS, Mojtahedzadeh M, Najafi A, et al. Improvement by N-acetylcysteine of acute respiratory distress syndrome through increasing intracellular gluthatione, and extra-cellular thiol molecules and antioxidant power: evidence for underlying toxicological mechanisms. Hum Exp Toxicol 2007; 26: 697-703.
11. Shadnia S, Dasgar M, Taghikhani S, Mohammadirad A, Khorasani R, Abdollahi M. Protective effects of alpha-tocopherol and N-acetyl cysteine on diazinon-induced oxidative stress and acetylcholinesterase inhibition in rats. Toxicol Mech Methods 2007; 17: 109-15.
12. Ansari G, Mojtahedzadeh M, Kajbaf F, et al. How does blood glucose control with metformin influence intensive insulin protocols? Evidence for involvement of oxidative stress and inflammatory cytokines. Adv Ther 2008; 25: 681-702.
13. Spies CD, Reinhart K, Witt I. Influence of N-acetylcysteine on indirect indicators of tissue oxygenation in septic shock patients: results from a prospective, randomized, double blind study. Crit Care Med 1994; 22: 1738-46.
14. Spapen H, Zhang H, Demanet C. Does N-acetyl cysteine influence cytokine response during early human septic shock? Chest 1998; 113: 1616-24.
15. Jespen S, Herlevsen P, Bud MI, Klausen AM. Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: a prospective, randomized, placebo-controlled study. Crit Care Med 1992; 20: 918-23.
16. Domenighetti G, Suter PM, Schaller MD, Ritz R, Perret C. Treatment with N-acetylcysteine during acute respiratory distress syndrome: a randomized, double-blind, placebo-controlled clinical study. J Crit Care 1997; 12: 177-82.
17. Agusti AG, Togores B, Ibanez J. Effects of N-acetyl cysteine on tissue oxygenation in patients with multiple organ failure and evidence of tissue hypoxia. Eur Respir J 1997; 10: 1962-6.
18. Pallister I, Gosling P, Alpar K, Bradley S. Prediction of post-traumatic adult respiratory distress syndrome by albumin excretion ratio eight hours after admission. J Trauma 1997; 42: 1056-61.
19. Pedersen LM. Clinical significance of urinary albumin excretion in patients with nonhodgkins lymphoma. Br J Haema 1997; 107: 889-91.
20. Abid O, Sun Q, Sugimoto K. Predictive value of microalbuminuria in medical ICU patients: Results of a pilot study. Chest 2001; 120: 1984-8.
21. Gosling P. Microalbuminuria: A marker of systemic disease. Br J Hosp Med 1995; 54: 285-90.
22. De Gaudio AR, Spina R, Di Filippo A. Glomerular permeability and trauma: a correlation between microalbuminuria and injury severity score. Crit Care Med 1999; 27: 2105-8.
23. Herbert D, Spapen P, Mare WD, Due N, Inne H, Lue PH. Effect of N-acetyl cysteine on microalbuminuria and organ failure in acute severe sepsis. Chest 2005; 127: 1413-9.
24. Molnar Z, Szakmany T, Heil P. Microalbuminuria does not reflect increased systemic capillary permeability in septic shock. Intensive Care Med 2003; 29: 391-5.
25. Gosling P, Beevers DG. Urinary albumin excretion and blood pressure in the general population. Clin Sci 1989; 76: 39-42.
26. Molnar Z, Shearer E, Lowe D. N-acetylcysteine treatment to prevent the progression of multisystem organ failure: A prospective, randomized, placebo-controlled study. Crit Care Med 1999; 27: 1100-4.
27. Dashti-Khavidaki S, Khalili H, Barzegar E, et al. Effect of 4-week treatment with oral N-acetylcysteine on plasma homocysteine concentration and antioxidant activity of patients on chronic hemodialysis. Kidney 2008; 17: 122-5.
28. Mojtahedzadeh M, Rouini MR, Kajbaf F, et al. Advantage of adjunct metformin and insulin therapy in the management of glycemia in critically ill patients. Evidence for nonoccurrence of lactic acidosis and needing to parenteral metformin. Arch Med Sci 2008; 4: 174-8.
29. Kajbaf F, Mojtahedzadeh M, Abdollahi M. Mechanisms underlying stress-induced hyperglycemia in critically ill patients. Therapy 2007; 4: 97-106.
30. Hadidi E, Mojtahedzadeh M, Rouini MR, et al. The evaluation of the possible effect of positive end expiratory pressure (PEEP) on pharmacokinetics of phenytoin in patients with acute brain injury under mechanical ventilation. DARU 2005; 13: 74-81.