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Volumn 3, Issue 6, 2009, Pages 693-699

Hepatitis B therapies and antiviral resistance detection and management

Author keywords

Biochemical breakthrough; Genotypic resistance; Hepatitis B; Virologic breakthrough

Indexed keywords

2 AMINO 9 (1 PHOSPHONOMETHOXYCYCLOPROPYLMETHYL)PURINE BIS(PIVALOYLOXYMETHYL) ESTER; ADEFOVIR; ALPHA INTERFERON; ALPHA2A INTERFERON; ANTIVIRUS AGENT; EMTRICITABINE; ENTECAVIR; LAMIVUDINE; NITAZOXANIDE; NUCLEOSIDE ANALOG; NUCLEOTIDE DERIVATIVE; PEGINTERFERON ALPHA; PEGINTERFERON ALPHA2A; PLACEBO; TELBIVUDINE; TENOFOVIR; TENOFOVIR DISOPROXIL; THYMOSIN ALPHA1; VIRUS DNA;

EID: 73449106125     PISSN: 17474124     EISSN: None     Source Type: Journal    
DOI: 10.1586/egh.09.64     Document Type: Review
Times cited : (3)

References (42)
  • 1
    • 67650469737 scopus 로고    scopus 로고
    • Hepatitis B-related hepatocellular carcinoma: Epidemiological characteristics and disease burden
    • Nguyen VT, Law MG, Dore GJ. Hepatitis B-related hepatocellular carcinoma: epidemiological characteristics and disease burden. J. Viral Hepat. 16, 453-463 (2009).
    • (2009) J. Viral Hepat , vol.16 , pp. 453-463
    • Nguyen, V.T.1    Law, M.G.2    Dore, G.J.3
  • 2
    • 33644858331 scopus 로고    scopus 로고
    • Predicting cirrhosis based on the level of circulating hepatitis B viral load
    • Iloeje UH, Yang HI, Su J et al. Predicting cirrhosis based on the level of circulating hepatitis B viral load. Gastroenterology 130, 678-686 (2006).
    • (2006) Gastroenterology , vol.130 , pp. 678-686
    • Iloeje, U.H.1    Yang, H.I.2    Su, J.3
  • 3
    • 35548938169 scopus 로고    scopus 로고
    • Long-term outcomes in hepatitis B: The REVEALHBV study
    • Chen CJ, Iloeje UH, Yang HI. Long-term outcomes in hepatitis B: the REVEALHBV study. Clin. Liver Dis. 11, 797-816 (2007).
    • (2007) Clin. Liver Dis , vol.11 , pp. 797-816
    • Chen, C.J.1    Iloeje, U.H.2    Yang, H.I.3
  • 4
    • 58149296156 scopus 로고    scopus 로고
    • EASL Clinical Practice Guidelines: Management of chronic hepatitis B
    • Pivotal practice guidelines for the management of chronic hepatitis B CHB, European Association for the Study of the Liver, ••
    • European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Management of chronic hepatitis B. J. Hepatol. 50, 227-242 (2009). •• Pivotal practice guidelines for the management of chronic hepatitis B (CHB).
    • (2009) J. Hepatol , vol.50 , pp. 227-242
  • 5
    • 57149091722 scopus 로고    scopus 로고
    • Special Report. A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update
    • Pivotal treatment algorithm for the management of CHB, ••
    • Keeffe EB, Dieterich DT, Han S-H B et al. Special Report. A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update. Clin. Gastroenterol. Hepatol. 6, 1315-1341 (2008). •• Pivotal treatment algorithm for the management of CHB.
    • (2008) Clin. Gastroenterol. Hepatol , vol.6 , pp. 1315-1341
    • Keeffe, E.B.1    Dieterich, D.T.2    Han, S.-H.B.3
  • 7
    • 0038713662 scopus 로고    scopus 로고
    • Fidelity of hepatitis B virus polymerase
    • Park SG, Kim Y, Park E et al. Fidelity of hepatitis B virus polymerase. Eur. J. Biochem. 270(14), 2929-2936 (2003).
    • (2003) Eur. J. Biochem , vol.270 , Issue.14 , pp. 2929-2936
    • Park, S.G.1    Kim, Y.2    Park, E.3
  • 8
    • 70350095437 scopus 로고    scopus 로고
    • Hepatits B virus resistance to nucleos(t)ide analogues
    • Zoulim F, Locarnini S. Hepatits B virus resistance to nucleos(t)ide analogues. Gastroeneterology 137(5), 1593-1608. (2009).
    • (2009) Gastroeneterology , vol.137 , Issue.5 , pp. 1593-1608
    • Zoulim, F.1    Locarnini, S.2
  • 9
    • 38749126832 scopus 로고    scopus 로고
    • Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: Recommendations for a standardized approach
    • Pivotal recommendation for a standardized approach to virologic monitoring of hepatitis B, •
    • Pawlotsky JM, Dusheiko G, Hatzakis A et al. Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach. Gastroenterology 134, 405-415 (2008). • Pivotal recommendation for a standardized approach to virologic monitoring of hepatitis B.
    • (2008) Gastroenterology , vol.134 , pp. 405-415
    • Pawlotsky, J.M.1    Dusheiko, G.2    Hatzakis, A.3
  • 10
    • 32444435768 scopus 로고    scopus 로고
    • HBV drug resistance: Mechanisms, detection and interpretation
    • Pivotal recommendation for detection and interpretation of hepatitis B virus drug resistance, •
    • Shaw T, Bartholomeusz A, Locarnini S. HBV drug resistance: mechanisms, detection and interpretation. J. Hepatol. 44, 593-606 (2006). • Pivotal recommendation for detection and interpretation of hepatitis B virus drug resistance.
    • (2006) J. Hepatol , vol.44 , pp. 593-606
    • Shaw, T.1    Bartholomeusz, A.2    Locarnini, S.3
  • 11
    • 68049133047 scopus 로고    scopus 로고
    • Hepatitis B treatment: Current best practices, avoiding resistance
    • Gish RG. Hepatitis B treatment: current best practices, avoiding resistance. Cleve. Clin. J. Med. 3, S14-S19 (2009).
    • (2009) Cleve. Clin. J. Med , vol.3
    • Gish, R.G.1
  • 12
    • 51049107683 scopus 로고    scopus 로고
    • Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2008 update
    • Pivotal practice guidelines for the management of CHB, ••
    • Liaw YF, Leung N, Kao JH, Piratvisuth T, Gane E, Han KH. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol. Int. 2, 263-283 (2008). •• Pivotal practice guidelines for the management of CHB.
    • (2008) Hepatol. Int , vol.2 , pp. 263-283
    • Liaw, Y.F.1    Leung, N.2    Kao, J.H.3    Piratvisuth, T.4    Gane, E.5    Han, K.H.6
  • 13
    • 0038045171 scopus 로고    scopus 로고
    • Peginterferon a-2a (40 kDa): An advance in the treatment of hepatitis B e antigenpositive chronic hepatitis B
    • Cooksley WG, Piratvisuth T, Lee SD et al. Peginterferon a-2a (40 kDa): an advance in the treatment of hepatitis B e antigenpositive chronic hepatitis B. J. Viral Hepat. 10, 298-305 (2003).
    • (2003) J. Viral Hepat , vol.10 , pp. 298-305
    • Cooksley, W.G.1    Piratvisuth, T.2    Lee, S.D.3
  • 14
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon a-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
    • Lau GK, Piratvisuth T, Luo KX et al. Peginterferon a-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N. Engl. J. Med. 352, 2682-2695 (2005).
    • (2005) N. Engl. J. Med , vol.352 , pp. 2682-2695
    • Lau, G.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 15
    • 51049114985 scopus 로고    scopus 로고
    • Recent data on treatment of chronic hepatitis B with nucleos(t)ide analogues
    • Leung N. Recent data on treatment of chronic hepatitis B with nucleos(t)ide analogues. Hepatol. Int. 2(2), 163-178 (2008).
    • (2008) Hepatol. Int , vol.2 , Issue.2 , pp. 163-178
    • Leung, N.1
  • 16
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • Chang TT, Gish RG, de Man R et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N. Engl. J. Med. 354, 1001-1010 (2006).
    • (2006) N. Engl. J. Med , vol.354 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3
  • 17
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
    • Lai CL, Shouval D, Lok AS et al. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N. Engl. J. Med. 354, 1011-1020 (2006).
    • (2006) N. Engl. J. Med , vol.354 , pp. 1011-1020
    • Lai, C.L.1    Shouval, D.2    Lok, A.S.3
  • 18
    • 33845675367 scopus 로고    scopus 로고
    • Entecavir resistance is rare in nucleoside naive patients with hepatitis B
    • Colonno RJ, Rose R, Baldick CJ et al. Entecavir resistance is rare in nucleoside naive patients with hepatitis B. Hepatology 44, 1656-1665 (2006).
    • (2006) Hepatology , vol.44 , pp. 1656-1665
    • Colonno, R.J.1    Rose, R.2    Baldick, C.J.3
  • 19
    • 33847683844 scopus 로고    scopus 로고
    • Two-year assessment of entecavir resistance in Lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present
    • Tenney DJ, Rose RE, Baldick CJ et al. Two-year assessment of entecavir resistance in Lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present. Antimicrob. Agents Chemother. 3, 902-911 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.3 , pp. 902-911
    • Tenney, D.J.1    Rose, R.E.2    Baldick, C.J.3
  • 20
    • 37349120537 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in patients with chronic hepatitis B
    • Lai CL, Gane E, Liaw YF et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N. Engl. J. Med. 357, 2576-2588 (2007).
    • (2007) N. Engl. J. Med , vol.357 , pp. 2576-2588
    • Lai, C.L.1    Gane, E.2    Liaw, Y.F.3
  • 21
    • 58649096155 scopus 로고    scopus 로고
    • 2-Year GLOBE trial results: Telbivudine is superior to lamivudine in patients with chronic hepatitis B
    • Liaw YF, Gane E, Leung N et al. 2-Year GLOBE trial results: telbivudine is superior to lamivudine in patients with chronic hepatitis B. Gastroenterology 136, 486-495 (2009).
    • (2009) Gastroenterology , vol.136 , pp. 486-495
    • Liaw, Y.F.1    Gane, E.2    Leung, N.3
  • 22
    • 38449093445 scopus 로고    scopus 로고
    • Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: A randomized trial
    • Chan HL, Heathcote EJ, Marcellin P et al. Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial. Ann. Intern. Med. 147, 745-754 (2007).
    • (2007) Ann. Intern. Med , vol.147 , pp. 745-754
    • Chan, H.L.1    Heathcote, E.J.2    Marcellin, P.3
  • 23
    • 10644275213 scopus 로고    scopus 로고
    • Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection
    • van Bommel F, Wunsche T, Mauss S et al. Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection. Hepatology 40, 1421-1425 (2004).
    • (2004) Hepatology , vol.40 , pp. 1421-1425
    • van Bommel, F.1    Wunsche, T.2    Mauss, S.3
  • 24
    • 51049122209 scopus 로고    scopus 로고
    • Tenofovir (TDF) has stronger antiviral effect than adefovir (ADV) against lamivudine (LAM) resistant hepatitis B virus (HBV)
    • Hann HW, Chae HB, Dunn SR. Tenofovir (TDF) has stronger antiviral effect than adefovir (ADV) against lamivudine (LAM) resistant hepatitis B virus (HBV). Hepatol. Int. 2(2), 244-249 (2008).
    • (2008) Hepatol. Int , vol.2 , Issue.2 , pp. 244-249
    • Hann, H.W.1    Chae, H.B.2    Dunn, S.R.3
  • 25
    • 57349095400 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
    • Marcellin P, Heathcote J, Buti M et al. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N. Engl. J. Med. 23, 2442-2455 (2008).
    • (2008) N. Engl. J. Med , vol.23 , pp. 2442-2455
    • Marcellin, P.1    Heathcote, J.2    Buti, M.3
  • 26
    • 70349240414 scopus 로고    scopus 로고
    • Chronic hepatitis B: Update 2009
    • Pivotal practice guidelines for the management of CHB, ••
    • Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology 50, 661-662 (2009). •• Pivotal practice guidelines for the management of CHB.
    • (2009) Hepatology , vol.50 , pp. 661-662
    • Lok, A.S.1    McMahon, B.J.2
  • 27
    • 0033798292 scopus 로고    scopus 로고
    • The impact of drug resistance on the effectiveness of chemotherapy for chronic hepatitis B
    • Richman DD. The impact of drug resistance on the effectiveness of chemotherapy for chronic hepatitis B. Hepatology 32, 866-867 (2000).
    • (2000) Hepatology , vol.32 , pp. 866-867
    • Richman, D.D.1
  • 28
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology 131, 1743-1751 (2006).
    • (2006) Gastroenterology , vol.131 , pp. 1743-1751
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 29
    • 73449138085 scopus 로고    scopus 로고
    • Entecavir maintains a high genetic barrier to HBV resistance through 6 years in naive patients. Prsented at
    • Copenhagen, Denmark, 22-26 April
    • Tenney DJ, Pokorowski KA, Rose RE et al. Entecavir maintains a high genetic barrier to HBV resistance through 6 years in naive patients. Prsented at: EASL 44th Annual Meeting. Copenhagen, Denmark, 22-26 April 2009.
    • (2009) EASL 44th Annual Meeting
    • Tenney, D.J.1    Pokorowski, K.A.2    Rose, R.E.3
  • 30
    • 34547425435 scopus 로고    scopus 로고
    • Antiviral drug-resistant HBV: Standardization of nomenclature and assays and recommendations for management
    • Pivotal practice guidelines for the management of CHB, ••
    • Lok AS, Zoulim F, Locarnini S et al. Antiviral drug-resistant HBV: standardization of nomenclature and assays and recommendations for management. Hepatology 46, 254-265 (2007). •• Pivotal practice guidelines for the management of CHB.
    • (2007) Hepatology , vol.46 , pp. 254-265
    • Lok, A.S.1    Zoulim, F.2    Locarnini, S.3
  • 31
    • 33847709539 scopus 로고    scopus 로고
    • Adding-on versus switching-to adefovir therapy in lamivudine-resistant in HBeAg-negative chronic hepatitis B
    • Rapti I, Dimou E, Mitsoula P, Hadziyannis SJ. Adding-on versus switching-to adefovir therapy in lamivudine-resistant in HBeAg-negative chronic hepatitis B. Hepatology 45, 307-313 (2007).
    • (2007) Hepatology , vol.45 , pp. 307-313
    • Rapti, I.1    Dimou, E.2    Mitsoula, P.3    Hadziyannis, S.J.4
  • 32
    • 62549091531 scopus 로고    scopus 로고
    • Virological techniques for the diagnosis and monitoring of hepatitis B and C
    • Chevaliez S, Pawlotsky JM. Virological techniques for the diagnosis and monitoring of hepatitis B and C. Ann. Hepatol. 8, 7-12 (2009).
    • (2009) Ann. Hepatol , vol.8 , pp. 7-12
    • Chevaliez, S.1    Pawlotsky, J.M.2
  • 33
    • 35648982926 scopus 로고    scopus 로고
    • Low resistance to adefovir combined with lamivudine: A 3-year study of 145 lamivudine-resistant hepatitis B patients
    • Lampertico P, Vigano M, Manenti E, Iavarone M, Sablon E, Colombo M. Low resistance to adefovir combined with lamivudine: a 3-year study of 145 lamivudine-resistant hepatitis B patients. Gastroenterology 133, 1445-1451 (2007).
    • (2007) Gastroenterology , vol.133 , pp. 1445-1451
    • Lampertico, P.1    Vigano, M.2    Manenti, E.3    Iavarone, M.4    Sablon, E.5    Colombo, M.6
  • 34
    • 69849093597 scopus 로고    scopus 로고
    • Variability of reverse transcriptase and overlapping S gene in hepatitis B virus isolates from untreated and lamivudineresistant chronic hepatitis B patients
    • Pollicino T, Isgro G, Di Stefano R et al. Variability of reverse transcriptase and overlapping S gene in hepatitis B virus isolates from untreated and lamivudineresistant chronic hepatitis B patients. Antivir. Ther. 14(5), 649-654 (2009).
    • (2009) Antivir. Ther , vol.14 , Issue.5 , pp. 649-654
    • Pollicino, T.1    Isgro, G.2    Di Stefano, R.3
  • 35
    • 34547148385 scopus 로고    scopus 로고
    • Report of an international workshop: Roadmap for management of patients receiving oral therapy for chronic hepatitis B
    • Keeffe EB, Zeuzem S, Koff, RS et al. Report of an international workshop: Roadmap for management of patients receiving oral therapy for chronic hepatitis B. Clin. Gastroenterol. Hepatol. 5, 890-897 (2007).
    • (2007) Clin. Gastroenterol. Hepatol , vol.5 , pp. 890-897
    • Keeffe, E.B.1    Zeuzem, S.2    Koff, R.S.3
  • 36
    • 62549089691 scopus 로고    scopus 로고
    • Prevention and management of drug resistance for antihepatitis B treatment
    • Yuen MF, Fung J, Wong DK, Lai CL. Prevention and management of drug resistance for antihepatitis B treatment. Lancet Infect. Dis. 9, 256-264 (2009).
    • (2009) Lancet Infect. Dis , vol.9 , pp. 256-264
    • Yuen, M.F.1    Fung, J.2    Wong, D.K.3    Lai, C.L.4
  • 37
    • 68649086002 scopus 로고    scopus 로고
    • Long-term therapy with clevudine for chronic hepatitis B can be associated with myopathy characterized by depletion of mitochondrial DNA
    • Seok Jl, Lee DK, Lee CH et al. Long-term therapy with clevudine for chronic hepatitis B can be associated with myopathy characterized by depletion of mitochondrial DNA. J. Hepatol. 49(6), 2080-2086 (2009).
    • (2009) J. Hepatol , vol.49 , Issue.6 , pp. 2080-2086
    • Seok, J.1    Lee, D.K.2    Lee, C.H.3
  • 38
    • 30344457555 scopus 로고    scopus 로고
    • A double-blind placebo-controlled study of emtricitabine in chronic hepatitis B
    • Lim SG, Ng TM, Kung N et al. A double-blind placebo-controlled study of emtricitabine in chronic hepatitis B. Arch. Intern. Med. 166(1), 49-56 (2006).
    • (2006) Arch. Intern. Med , vol.166 , Issue.1 , pp. 49-56
    • Lim, S.G.1    Ng, T.M.2    Kung, N.3
  • 39
    • 67651251216 scopus 로고    scopus 로고
    • Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides
    • Keeffe EB, Rossignol JF. Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides. World J. Gastroenterol. 15, 1808-1808 (2009).
    • (2009) World J. Gastroenterol , vol.15 , pp. 1808-1808
    • Keeffe, E.B.1    Rossignol, J.F.2
  • 40
    • 0035663014 scopus 로고    scopus 로고
    • The efficacy of thymosin in the treatment of chronic hepatitis B virus infection: A meta-analysis
    • Chan HL, Tang JL, Tam W, Sung JJ. The efficacy of thymosin in the treatment of chronic hepatitis B virus infection: a meta-analysis. Aliment. Pharmacol. Ther. 15, 1899-1905 (2001).
    • (2001) Aliment. Pharmacol. Ther , vol.15 , pp. 1899-1905
    • Chan, H.L.1    Tang, J.L.2    Tam, W.3    Sung, J.J.4
  • 41
    • 66149185685 scopus 로고    scopus 로고
    • Benefits and risks of combination therapy for hepatitis B
    • Terrault N. Benefits and risks of combination therapy for hepatitis B. Hepatology 49(5 Suppl.), S122-S128 (2009).
    • (2009) Hepatology , vol.49 , Issue.5 SUPPL.
    • Terrault, N.1
  • 42
    • 58849156898 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis B: Are we ready for combination therapy?
    • Seetharam A, Lisker-melman M. Treatment of chronic hepatitis B: are we ready for combination therapy? Liver 11, 22-27 (2009).
    • (2009) Liver , vol.11 , pp. 22-27
    • Seetharam, A.1    Lisker-melman, M.2


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