NIK and IKKβ interdependence in NF-κB signalling-Flux analysis of regulation through metabolites

BioSystems

Volumn 99, Issue 2, 2010, Pages 140-149

  Kim, Hong Bum ^a   Evans, Iona ^a   Smallwood, Rod ^a   Holcombe, Mike ^a   Qwarnstrom, Eva E ^a,b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cell culture; Immune system; Kinase; Metabolic flux analysis; NF B; Transfection

Indexed keywords

I KAPPA B ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR FACTOR B INDUCING KINASE; PHOSPHORIBOSYL PYROPHOSPHATE; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; I KAPPA B; I KAPPA B KINASE; NF KAPPA B KINASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPA B KINASE; NF-KAPPAB INHIBITOR ALPHA; PROTEIN SERINE THREONINE KINASE;

ENZYME ACTIVITY; IMMUNE SYSTEM; METABOLITE; NUMERICAL MODEL;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; GLYCOLYSIS; GROWTH RATE; HUMAN; HUMAN CELL; IN VITRO STUDY; MATHEMATICAL MODEL; METABOLIC REGULATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOICHIOMETRY; THEORETICAL STUDY; BIOLOGICAL MODEL; CELL CULTURE; GENETIC TRANSFECTION; GENETICS; METABOLISM; MUTATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELLS, CULTURED; GREEN FLUORESCENT PROTEINS; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; MODELS, BIOLOGICAL; MUTATION; NF-KAPPA B; PHOSPHORIBOSYL PYROPHOSPHATE; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFECTION;

EID: 73449094820     PISSN: 03032647     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biosystems.2009.10.009     Document Type: Article

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