The orexin-1 receptor antagonist SB-334867 reduces amphetamine-evoked dopamine outflow in the shell of the nucleus accumbens and decreases the expression of amphetamine sensitization

Neurochemistry International

Volumn 56, Issue 1, 2010, Pages 11-15

  Quarta, Davide ^a   Valerio, Enzo ^a   Hutcheson, Daniel M ^a   Hedou, Gael ^a   Heidbreder, Christian ^a  

^a GSK   (Italy)

Author keywords

Accumbens shell; Amphetamine; Dopamine; Microdialysis; Orexin; Sensitization

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; AMPHETAMINE; DOPAMINE; OREXIN 1 RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPULSION; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG MECHANISM; DRUG USE; IN VIVO STUDY; LOCOMOTION; MALE; MICRODIALYSIS; NEUROCHEMISTRY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SENSITIZATION;

AMPHETAMINE; AMPHETAMINE-RELATED DISORDERS; ANIMALS; BENZOXAZOLES; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; EXTRACELLULAR FLUID; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICRODIALYSIS; NEURAL PATHWAYS; NEUROPEPTIDES; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; REWARD; SYNAPTIC TRANSMISSION; UREA;

RATTUS;

EID: 73449092478     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.08.012     Document Type: Article

References (46)

1. Akimoto K., Hamamura T., Kazahaya Y., Akiyama K., and Otsuki S. Enhanced extracellular dopamine level may be the fundamental neuropharmacological basis of cross-behavioral sensitization between methamphetamine and cocaine-an in vivo dialysis study in freely moving rats. Brain Res. 507 (1990) 344-346
2. Balcita-Pedicino J.J., and Sesack S.R. Orexin axons in the rat ventral tegmental area synapse infrequently onto dopamine and gamma-aminobutyric acid neurons. J. Comp. Neurol. 503 (2007) 668-684
3. Borgland S.L., Storm E., and Bonci A. Orexin B/hypocretin 2 increases glutamatergic transmission to ventral tegmental area neurons. Eur. J. Neurosci. 28 (2008) 1545-1556
4. Borgland S.L., Taha S.A., Sarti F., Fields H.L., and Bonci A. Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine. Neuron 49 (2006) 589-601
5. Brisbare-Roch C., Dingemanse J., Koberstein R., Hoever P., Aissaoui H., Flores S., Mueller C., Nayler O., van Gerven J., de Haas S.L., Hess P., Qiu C., Buchmann S., Scherz M., Weller T., Fischli W., Clozel M., and Jenck F. Promotion of sleep by targeting the orexin system in rats, dogs and humans. Nat. Med. 13 (2007) 150-155
6. Cador M., Bjijou Y., and Stinus L. Evidence of a complete independence of the neurobiological substrates for the induction and expression of behavioral sensitization to amphetamine. Neuroscience 65 (1995) 385-395
7. Carr D., and Kalivas P.W. Orexin: a gatekeeper of addiction. Nat. Med. 12 (2006) 274-276
8. De Vries T.J., Schoffelmeer A.N., Binnekade R., Mulder A.H., and Vanderschuren L.J. Drug-induced reinstatement of heroin- and cocaine-seeking behaviour following long-term extinction is associated with expression of behavioural sensitization. Eur. J. Neurosci. 10 (1998) 3565-3571
9. Harris G.C., Wimmer M., and Aston-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature 437 (2005) 556-559
10. Heidbreder C., Shoaib M., and Shippenberg T.S. Differential role of delta-opioid receptors in the development and expression of behavioral sensitization to cocaine. Eur. J. Pharmacol. 298 (1996) 207-216
11. Heidbreder C.A., Lacroix L., Atkins A.R., Organ A.J., Murray S., West A., and Shah A.J. Development and application of a sensitive high performance ion-exchange chromatography method for the simultaneous measurement of dopamine, 5-hydroxytryptamine and norepinephrine in microdialysates from the rat brain. J. Neurosci. Methods 112 (2001) 135-144
12. Heidbreder C.A., Thompson A.C., and Shippenberg T.S. Role of extracellular dopamine in the initiation and long-term expression of behavioral sensitization to cocaine. J. Pharmacol. Exp. Ther. 278 (1996) 490-502
13. Hernandez L.F., Segovia G., and Mora F. Chronic treatment with a dopamine uptake blocker changes dopamine and acetylcholine but not glutamate and GABA concentrations in prefrontal cortex, striatum and nucleus accumbens of the awake rat. Neurochem. Int. 52 (2008) 457-469
14. Hitzemann R.J., Tseng L.F., Hitzemann B.A., Sampath-Khanna S., and Loh H.H. Effects of withdrawal from chronic amphetamine intoxication on exploratory and stereotyped behaviors in the rat. Psychopharmacology (Berlin) 54 (1977) 295-302
15. Kalivas P.W., and Duffy P. Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens. Synapse 5 (1990) 48-58
16. Kalivas P.W., and Stewart J. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res. Brain Res. Rev. 16 (1991) 223-244
17. Kalivas P.W., and Weber B. Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine. J. Pharmacol. Exp. Ther. 245 (1988) 1095-1102
18. Karler R., Calder L.D., and Bedingfield J.B. Cocaine behavioral sensitization and the excitatory amino acids. Psychopharmacology (Berlin) 115 (1994) 305-310
19. Karler R., Calder L.D., and Turkanis S.A. DNQX blockade of amphetamine behavioral sensitization. Brain Res. 552 (1991) 295-300
20. Korotkova T.M., Sergeeva O.A., Eriksson K.S., Haas H.L., and Brown R.E. Excitation of ventral tegmental area dopaminergic and nondopaminergic neurons by orexins/hypocretins. J. Neurosci. 23 (2003) 7-11
21. Lawrence A.J., Cowen M.S., Yang H.J., Chen F., and Oldfield B. The orexin system regulates alcohol-seeking in rats. Br. J. Pharmacol. 148 (2006) 752-759
22. Mieda M., and Yanagisawa M. Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors. Curr. Opin. Neurobiol. 12 (2002) 339-345
23. Mullett M.A., Billington C.J., Levine A.S., and Kotz C.M. Hypocretin I in the lateral hypothalamus activates key feeding-regulatory brain sites. Neuroreport 11 (2000) 103-108
24. Nair S.G., Golden S.A., and Shaham Y. Differential effects of the hypocretin 1 receptor antagonist SB 334867 on high-fat food self-administration and reinstatement of food seeking in rats. Br. J. Pharmacol. 154 (2008) 406-416
25. Nakamura T., Uramura K., Nambu T., Yada T., Goto K., Yanagisawa M., and Sakurai T. Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system. Brain Res. 873 (2000) 181-187
26. Narita M., Nagumo Y., Hashimoto S., Khotib J., Miyatake M., Sakurai T., Yanagisawa M., Nakamachi T., Shioda S., and Suzuki T. Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine. J. Neurosci. 26 (2006) 398-405
27. Parsons L.H., and Justice Jr. J.B. Serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration. J. Neurochem. 61 (1993) 1611-1619
28. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1987), Academic Press, Sydney, Australia
29. Pettit H.O., Pan H.T., Parsons L.H., and Justice Jr. J.B. Extracellular concentrations of cocaine and dopamine are enhanced during chronic cocaine administration. J. Neurochem. 55 (1990) 798-804
30. Peyron C., Tighe D.K., van den Pol A.N., de Lecea L., Heller H.C., Sutcliffe J.G., and Kilduff T.S. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J. Neurosci. 18 (1998) 9996-10015
31. Post R.M. Intermittent versus continuous stimulation: effect of time interval on the development of sensitization or tolerance. Life Sci. 26 (1980) 1275-1282
32. Quarta D., Di Francesco C., Melotto S., Mangiarini L., Heidbreder C., and Hedou G. Systemic administration of ghrelin increases extracellular dopamine in the shell but not the core subdivision of the nucleus accumbens. Neurochem. Int. 54 (2009) 89-94
33. Richards J.K., Simms J.A., Steensland P., Taha S.A., Borgland S.L., Bonci A., and Bartlett S.E. Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats. Psychopharmacology (Berlin) 199 (2008) 109-117
34. Robinson T.E., and Becker J.B. Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis. Brain Res. 396 (1986) 157-198
35. Robinson T.E., and Berridge K.C. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res. Brain Res. Rev. 18 (1993) 247-291
36. Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., Williams S.C., Richardson J.A., Kozlowski G.P., Wilson S., Arch J.R., Buckingham R.E., Haynes A.C., Carr S.A., Annan R.S., McNulty D.E., Liu W.S., Terrett J.A., Elshourbagy N.A., Bergsma D.J., and Yanagisawa M. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 92 (1998) 573-585
37. Sakurai T., Moriguchi T., Furuya K., Kajiwara N., Nakamura T., Yanagisawa M., and Goto K. Structure and function of human prepro-orexin gene. J Biol Chem. 274 (1999) 17771-17776
38. Scammell T.E., and Saper C.B. Orexins: looking forward to sleep, back at addiction. Nat Med. 13 (2007) 126-128
39. Schilstrom B., Yaka R., Argilli E., Suvarna N., Schumann J., Chen B.T., Carman M., Singh V., Mailliard W.S., Ron D., and Bonci A. Cocaine enhances NMDA receptor-mediated currents in ventral tegmental area cells via dopamine D5 receptor-dependent redistribution of NMDA receptors. J. Neurosci. 26 (2006) 8549-8558
40. Segal D.S., and Kuczenski R. In vivo microdialysis reveals a diminished amphetamine-induced DA response corresponding to behavioral sensitization produced by repeated amphetamine pretreatment. Brain Res. 571 (1992) 330-337
41. Smart D., Sabido-David C., Brough S.J., Jewitt F., Johns A., Porter R.A., and Jerman J.C. SB-334867-A: the first selective orexin-1 receptor antagonist. Br. J. Pharmacol. 132 (2001) 1179-1182
42. Sorensen G., Wegener G., Hasselstrom J., Hansen T.V., Wortwein G., Fink-Jensen A., and Woldbye D.P. Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine. Neuroreport 20 (2009) 1023-1026
43. Sperlagh B., Windisch K., Ando R.D., and Sylvester Vizi E. Neurochemical evidence that stimulation of CB1 cannabinoid receptors on GABAergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens. Neurochem. Int. 54 (2009) 452-457
44. Vittoz N.M., and Berridge C.W. Hypocretin/orexin selectively increases dopamine efflux within the prefrontal cortex: involvement of the ventral tegmental area. Neuropsychopharmacology 31 (2006) 384-395
45. White F.J., Joshi A., Koeltzow T.E., and Hu X.T. Dopamine receptor antagonists fail to prevent induction of cocaine sensitization. Neuropsychopharmacology 18 (1998) 26-40
46. Wolf M.E. The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants. Prog. Neurobiol. 54 (1998) 679-720