Effects of loratadine/montelukast on vigilance and alertness task Performance in a simulated cabin environment

Advances in Therapy

Volumn 26, Issue 1, 2009, Pages 89-98

  Valk, P J L ^a   Simons, M ^a  

^a TNO   (Netherlands)

Author keywords

Antihistamine; Antileukotriene; Cognitive performance; Diphenhydramine; Loratadine montelukast; Multi Attribute Task Battery; Quality of life; Seasonal allergic rhinitis; Stanford Sleepiness Scale; Vigilance and Tracking Task

Indexed keywords

DIPHENHYDRAMINE; LORATADINE; MONTELUKAST; PLACEBO;

ABDOMINAL PAIN; ADULT; ALERTNESS; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG WITHDRAWAL; FATIGUE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PSYCHOMOTOR PERFORMANCE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SEDATION; SINGLE DRUG DOSE; SLEEP PARAMETERS; SOMNOLENCE; STANFORD SLEEPINESS SCALE; TASK PERFORMANCE; UPPER RESPIRATORY TRACT INFECTION;

ACETATES; ADULT; ALTITUDE; ANTI-ALLERGIC AGENTS; ATMOSPHERIC PRESSURE; CROSS-OVER STUDIES; DIPHENHYDRAMINE; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; HUMANS; LORATADINE; MALE; PSYCHOMOTOR PERFORMANCE; QUINOLINES; YOUNG ADULT;

EID: 73449092183     PISSN: 0741238X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12325-008-0127-6     Document Type: Article

References (22)

1. R.J. Salib A. Drake-Lee P.H. Howarth 2003 Allergic rhinitis: past, present and the future Clin Otolaryngol Allied Sci. 28 291 303 12871241 10.1046/j.1365-2273.2003.00706.x 1:STN:280:DC%2BD3szosVemtg%3D%3D (Pubitemid 36960265)
2. J. Bousquet F. Neukirch P.J. Bousquet 2006 Severity and impairment of allergic rhinitis in patients consulting in primary care J Allergy Clin Immunol. 117 158 162 16387600 10.1016/j.jaci.2005.09.047 (Pubitemid 43017154)
3. R.J. Green G. Davis D. Price 2007 Concerns of patients with allergic rhinitis: the Allergic Rhinitis Care Programme in South Africa Prim Care Respir J 16 299 303 17934676 10.3132/pcrj.2007.00062 (Pubitemid 47607072)
4. D.E. Stull L. Roberts L. Frank K. Heithoff 2007 Relationship of nasal congestion with sleep, mood, and productivity Curr Med Res Opin. 23 811 819 17407638 10.1185/030079907X178793 (Pubitemid 46631484)
5. A. Shedden 2005 Impact of nasal congestion on quality of life and work productivity in allergic rhinitis: findings from a large online survey Treat Respir Med. 4 439 446 16336028 10.2165/00151829-200504060-00007 (Pubitemid 41803329)
6. R. Sundberg K. Toren D. Hoglund N. Aberg J. Brisman 2007 Nasal symptoms are associated with school performance in adolescents J Adolesc Health 40 581 583 17531771 10.1016/j.jadohealth.2007.01.003 (Pubitemid 46783884)
7. S.L. Szeinbach E.C. Seoane-Vazquez A. Beyer P.B. Williams 2007 The impact of allergic rhinitis on work productivity Prim Care Respir J 16 98 105 17404676 10.3132/pcrj.2007.00015 (Pubitemid 46698774)
8. J.P. Corey S.M. Houser B.A. Ng 2000 Nasal congestion: a review of its etiology, evaluation, and treatment Ear Nose Throat J 79 690 702 11011488 1:STN:280:DC%2BD3cvlsVWiug%3D%3D
9. J. Stokes E. Fenstad T.B. Casale 2006 Managing impairment in patients with allergic rhinitis Allergy Asthma Proc. 27 12 16 16598987 1:CAS:528:DC%2BD28XjtlGku7o%3D
10. T.B. Casale M.S. Blaiss E. Gelfand 2003 First do no harm: managing antihistamine impairment in patients with allergic rhinitis J Allergy Clin Immunol. 111 S835 S842 12743547 10.1016/S0091-6749(03)80182-3
11. A. Sen A. Akin K.J. Craft D.V. Canfield A.K. Chaturvedi 2007 First-generation H1 antihistamines found in pilot fatalities of civil aviation accidents, 1990-2005 Aviat Space Environ Med. 78 514 522 17539447
12. C.A. Eriksen T. Akerstedt 2006 Aircrew fatigue in trans-Atlantic morning and evening flights Chronobiol Int. 23 843 858 16887752 10.1080/ 07420520600865574 (Pubitemid 44186971)
13. N. Wright A. McGown 2001 Vigilance on the civil flight deck: incidence of sleepiness and sleep during long-haul flights and associated changes in physiological parameters Ergonomics 44 82 106 11214900 10.1080/00140130150203893 1:STN:280:DC%2BD3M7kvFCqsg%3D%3D
14. A.K. Chaturvedi K.J. Craft D.V. Canfield J.E. Whinnery 2005 Toxicological findings from 1587 civil aviation accident pilot fatalities, 1999-2003 Aviat Space Environ Med. 76 1145 1150 16370264 1:CAS:528:DC%2BD28XnvFI%3D
15. J.W. Soper A.K. Chaturvedi D.V. Canfield 2000 Prevalence of chlorpheniramine in aviation accident pilot fatalities, 1991-1996 Aviat Space Environ Med. 71 1206 1209 11439720 1:STN:280:DC%2BD3Mzos1Cisg%3D%3D
16. G.C. Butler J. Nicholas D.T. Lackland W. Friedberg 2000 Perspectives of those impacted: airline pilot's perspective Health Phys. 79 602 607 11045538 10.1097/00004032-200011000-00021 1:CAS:528:DC%2BD3cXnsl2hurs%3D
17. A. Smith 2005 Hypoxia symptoms reported during helicopter operations below 10,000 ft: a retrospective survey Aviat Space Environ Med. 76 794 798 16110698
18. P. Valk M. Simons P. Struyvenberg H. Kruit M. Van berge Hengouwen 1997 Effects of a single dose of loratadine on flying ability under conditions of simulated cabin pressure Am J Rhinology 11 27 33 10.2500/105065897781446838 1:STN:280:DyaK2s3hslGiuw%3D%3D
19. G.G. Kay B. Berman S.H. Mockoviak 1997 Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance Arch Intern Med. 157 2350 2356 9361576 10.1001/archinte.157.20.2350 1:CAS:528:DyaK2sXns1emur0%3D
20. Simons M, Valk P, de Ree J, Veldhuijzen van Zanten O, D'Huyvetter K. Quantity and quality of onboard and layover sleep; effects on crew performance and alertness. Soesterberg, The Netherlands: Netherlands Aerospace Medical Centre; 1994.
21. G.G. Kay A.G. Harris 1999 Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation Clin Exp Allergy 29 suppl.3 147 150 10444229 10.1046/j.1365-2222.1999.0290s3147. x 1:CAS:528:DyaK1MXltVOgu7o%3D
22. J.M. Weiler J.R. Bloomfield G.G. Woodworth 2000 Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator Ann Intern Med. 132 354 363 10691585 1:CAS:528:DC%2BD3cXhvFektrw%3D