Patients with low rectal cancer treated by abdominoperineal excision have worse tumors and higher involved margin rates compared with patients treated by anterior resection

Diseases of the Colon and Rectum

Volumn 53, Issue 1, 2010, Pages 53-56

  Shihab, Oliver C ^a   Brown, Gina ^b   Daniels, Ian R ^c   Heald, Richard J ^a   Quirke, Philip ^d   Moran, Brendan J ^e  

^a PELICAN CANCER FOUNDATION   (United Kingdom)

^b ROYAL MARSDEN HOSPITAL   (United Kingdom)

^c ROYAL DEVON AND EXETER HOSPITAL   (United Kingdom)

^d ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^e NORTH HAMPSHIRE HOSPITAL   (United Kingdom)

Author keywords

Abdominoperineal excision; Low rectal cancer

Indexed keywords

ADJUVANT THERAPY; ADULT; ADVANCED CANCER; ARTICLE; CANCER INVASION; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PATIENT SAFETY; RECTUM ABDOMINOPERINEAL RESECTION; RECTUM ANTERIOR RESECTION; RECTUM CANCER; STATISTICAL SIGNIFICANCE; SURGICAL APPROACH; SURGICAL TECHNIQUE; TREATMENT OUTCOME; TUMOR PERFORATION; ADENOCARCINOMA; AGED; COLON; COLON RESECTION; COMPARATIVE STUDY; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PERINEUM; PROGNOSIS; RECTUM; RECTUM TUMOR;

ADENOCARCINOMA; AGED; COLECTOMY; COLON; FEMALE; HUMANS; MALE; MIDDLE AGED; PERINEUM; PROGNOSIS; RECTAL NEOPLASMS; RECTUM;

EID: 73449090498     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/DCR.0b013e3181c70465     Document Type: Article

References (19)

1. Nagtegaal ID, van de Velde CJH, Marijnen CAM, van Krieken JHJM, Quirke P. Low rectal cancer: a call for a change of approach in abdominoperineal resection. J Clin Oncol. 2005;23: 9257-9264
2. Kapiteijn E, Marijnen CAM, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med. 2001;345:638-646 (Pubitemid 34936565)
3. Marr R, Birbeck K, Garvican J, et al. The modern abdominoperineal excision: the next challenge after total mesorectal excision. Ann Surg. 2005;242:74-82.
4. Wibe A, Syse A, Andersen E, et al. Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection. Dis Colon Rectum. 2004;47:48-58.
5. Heald RJ, Chir M, Smedh RK, Kald A, Sexton R, Moran BJ. abdominoperineal excision of the rectum-an endangered operation. Dis Colon Rectum. 1997;40:747-751
6. Eriksen MT, Wibe A, Syse A, Haffner J, Wiig JN. Inadvertent perforation during rectal cancer resection in Norway. Br J Surg. 2004;91:210-216
7. Zirngibl H, Husemann B, Hermanek P. Intraoperative spillage of tumor cells in surgery for rectal cancer. Dis Colon Rectum. 1990;33:610-614
8. The MERCURY Study Group. Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study. BMJ. 2006;333:779-784
9. Maslekar S, Sharma A, MacDonald A, Gunn J, Monson J, Hartley J. Mesorectal grades predict recurrences after curative resection for rectal cancer. Dis Colon Rectum. 2007;50:168-175
10. Hyuk Baik S, Kyu Kim N, Young Lee K, et al. Factors influencing pathologic results after total mesorectal excision for rectal cancer: analysis of consecutive 100 cases. Ann Surg Oncol. 2008;15: 721-728
11. Quirke P, Dixon MF, Durdey P, Williams NS. Local recurrence of rectal adenocarcinoma due to inadequate surgical resection: histopathological study of lateral tumour spread and surgical excision. Lancet. 1986;328:996-999
12. Quirke P, Dixon MF. The prediction of local recurrence in rectal adenocarcinoma by histopathological examination. Int J Colorectal Dis. 1988;3:127-131
13. Adam IJ, Martin IG, Finan P, et al. Role of circumferential margin involvement in the local recurrence of rectal cancer. Lancet. 1994;344:707-711
14. De Haas-Kock DFM, Baeten CGMI, Jager JJ, et al. Prognostic significance of radial margins of clearance in rectal cancer. Br J Surg. 1996;83:781-785
15. Guillou PJ, Quirke P, Thorpe H, et al. Short-term endpoints of conventional vs. laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet. 2005;365:1718-1726
16. Tilney H, Tekkis P, Sains P, Constantinides V, Heriot A, on behalf of the Association of Coloproctology of Great Britain and Ireland. Factors affecting circumferential resection margin involvement after rectal cancer excision. Dis Colon Rectum. 2007; 50:29-36.
17. Nagtegaal ID, van de Velde CJH, van der Worp E, Kapiteijn E, Quirke P, van Krieken JHJM. Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol. 2002;20:1729-1734
18. Holm T, Ljung A, Häggmark T, Jurell G, Lagergren J. Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer. Br J Surg. 2007;94: 232-238
19. West NP, Finan PJ, Anderin C, Lindholm J, Holm T, Quirke P. Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer. J Clin Oncol. 2008;26: 3517-3522